JP2009543813A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2009543813A5 JP2009543813A5 JP2009519769A JP2009519769A JP2009543813A5 JP 2009543813 A5 JP2009543813 A5 JP 2009543813A5 JP 2009519769 A JP2009519769 A JP 2009519769A JP 2009519769 A JP2009519769 A JP 2009519769A JP 2009543813 A5 JP2009543813 A5 JP 2009543813A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- pharmaceutically acceptable
- acceptable salt
- acid
- nsaid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- JEECSZAPQXTBRX-UHFFFAOYSA-N CC(Oc1ccccc1C(Oc(cc1)ccc1C1=CC(S)SS1)=O)=O Chemical compound CC(Oc1ccccc1C(Oc(cc1)ccc1C1=CC(S)SS1)=O)=O JEECSZAPQXTBRX-UHFFFAOYSA-N 0.000 description 1
- QXYZSNGZMDVLKN-UHFFFAOYSA-N Cc(cc1)ccc1C(N)=S Chemical compound Cc(cc1)ccc1C(N)=S QXYZSNGZMDVLKN-UHFFFAOYSA-N 0.000 description 1
- VZVOTQGHDNUUFT-UHFFFAOYSA-N Cc(cc1)ccc1C(SS1)=CC1=S Chemical compound Cc(cc1)ccc1C(SS1)=CC1=S VZVOTQGHDNUUFT-UHFFFAOYSA-N 0.000 description 1
- HIPHYBWWZWRZOV-UHFFFAOYSA-N Oc(cc1)ccc1N=C=S Chemical compound Oc(cc1)ccc1N=C=S HIPHYBWWZWRZOV-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80763906P | 2006-07-18 | 2006-07-18 | |
| US60/807,639 | 2006-07-18 | ||
| US88718807P | 2007-01-30 | 2007-01-30 | |
| US60/887,188 | 2007-01-30 | ||
| PCT/CA2007/001289 WO2008009127A1 (en) | 2006-07-18 | 2007-07-18 | Hydrogen sulfide derivatives of non-steroidal anti-inflammatory drugs |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009543813A JP2009543813A (ja) | 2009-12-10 |
| JP2009543813A5 true JP2009543813A5 (https=) | 2010-08-19 |
| JP5408719B2 JP5408719B2 (ja) | 2014-02-05 |
Family
ID=38956479
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009519765A Expired - Fee Related JP5529534B2 (ja) | 2006-07-18 | 2007-07-18 | ４−ヒドロキシチオベンズアミド薬剤誘導体 |
| JP2009519769A Active JP5408719B2 (ja) | 2006-07-18 | 2007-07-18 | 非ステロイド系抗炎症薬の硫化水素誘導体 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009519765A Expired - Fee Related JP5529534B2 (ja) | 2006-07-18 | 2007-07-18 | ４−ヒドロキシチオベンズアミド薬剤誘導体 |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US8314140B2 (https=) |
| EP (2) | EP2041108B1 (https=) |
| JP (2) | JP5529534B2 (https=) |
| KR (2) | KR101450653B1 (https=) |
| AU (2) | AU2007276679B2 (https=) |
| BR (2) | BRPI0714330A2 (https=) |
| CA (2) | CA2658429A1 (https=) |
| DK (1) | DK2057139T3 (https=) |
| ES (1) | ES2437223T3 (https=) |
| IL (2) | IL196229A (https=) |
| MX (2) | MX2009000749A (https=) |
| NO (2) | NO20090764L (https=) |
| NZ (1) | NZ573996A (https=) |
| PL (1) | PL2057139T3 (https=) |
| PT (1) | PT2057139E (https=) |
| RU (2) | RU2468019C2 (https=) |
| WO (2) | WO2008009118A1 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7741359B2 (en) * | 2005-05-27 | 2010-06-22 | Antibe Therapeutics Inc. | Hydrogen sulfide derivatives of non-steroidal anti-inflammatory drugs |
| DK2057139T3 (da) * | 2006-07-18 | 2013-11-18 | Antibe Holdings Inc | Hydrogensulfidderivater af non-steroide anti-inflammatoriske lægemidler |
| ITMI20080382A1 (it) * | 2008-03-07 | 2009-09-08 | Ctg Pharma S R L | Composizioni farmaceutiche oculari |
| ITMI20081167A1 (it) * | 2008-06-26 | 2009-12-27 | Ctg Pharma S R L | Composizioni farmaceutiche per il trattamento di malattie neurodegenerative |
| US8541396B2 (en) | 2009-04-24 | 2013-09-24 | National University Of Singapore | Morpholin-4-ium 4 methoxyphenyl (morpholino) phosphinodithioate (GYY4137) as a novel vasodilator agent |
| WO2011053597A1 (en) * | 2009-10-26 | 2011-05-05 | The University Of Memphis Research Foundation | Pipemidic acid derivative autotaxin inhibitors |
| US9242009B2 (en) | 2012-07-17 | 2016-01-26 | The General Hospital Corporation | Compositions and methods to treat neurodegenerative diseases |
| AU2017263574B2 (en) | 2016-05-12 | 2022-11-17 | The Regents Of The University Of Michigan | ASH1L inhibitors and methods of treatment therewith |
| WO2019094772A1 (en) | 2017-11-10 | 2019-05-16 | The Regents Of The University Of Michigan | Ash1l degraders and methods of treatment therewith |
| JP2021066660A (ja) * | 2018-02-09 | 2021-04-30 | アピオン・ジャパン有限会社 | Ｔｉｒａｐ阻害剤 |
| WO2022115952A1 (en) * | 2020-12-03 | 2022-06-09 | Antibe Therapeutics Inc. | [1-(4-chloro-benzoyl)-5-methoxy-2-methyl-1h-indol-3-yl]-acetic acid 4-thiocarbamoyl-phenyl ester for the treatment of a viral infection |
| WO2023159296A1 (en) * | 2022-02-28 | 2023-08-31 | Antibe Therapeutics Inc. | 4-thiocarbamoylphenyl 2-(4-oxophenyl)-phenyl propanoate for the treatment of pain associated with urologic chronic pelvic pain syndrome |
| GR1010438B (el) * | 2022-03-21 | 2023-04-06 | UNI-PHARMA ΚΛΕΩΝ ΤΣΕΤΗΣ ΦΑΡΜΑΚΕΥΤΙΚΑ ΕΡΓΑΣΤΗΡΙΑ ΑΒΕΕ με δ.τ. "UNI-PHARMA ABEE", | Φαρμακευτικες ενωσεις που βασιζονται στο συνδυασμο ενος ανταγωνιστη της ισταμινης και ενος δοτη υδροθειου για χρηση στην αντιμετωπιση του κνησμου |
| WO2025076616A1 (en) * | 2023-10-11 | 2025-04-17 | Antibe Therapeutics Inc. | Polymorphic forms of otenaproxesul and compositions and uses thereof |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE612252A (https=) * | 1961-01-05 | |||
| US4170654A (en) * | 1976-02-13 | 1979-10-09 | Merck & Co., Inc. | Antihypertensive compositions containing N-heterocyclicalanines and α- |
| US4112095A (en) * | 1976-10-07 | 1978-09-05 | American Cyanamid Company | 6-Phenyl-1,2,4-triazolo[4,3-b]pyridazine hypotensive agents |
| US5214191A (en) * | 1990-05-22 | 1993-05-25 | Cortech, Inc. | Oxidant sensitive and insensitive aromatic esters as inhibitors of human neutrophil elastase |
| US5663416A (en) * | 1990-05-22 | 1997-09-02 | Cortech Inc. | Oxidant sensitive and insensitive aromatic esters as inhibitors of human neutrophil elastase |
| EP0937711A1 (de) | 1998-02-18 | 1999-08-25 | Roche Diagnostics GmbH | Neue Thiobenzamide, Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel |
| IT1311924B1 (it) * | 1999-04-13 | 2002-03-20 | Nicox Sa | Composti farmaceutici. |
| IT1314184B1 (it) * | 1999-08-12 | 2002-12-06 | Nicox Sa | Composizioni farmaceutiche per la terapia di condizioni di stressossidativo |
| US6429223B1 (en) * | 2000-06-23 | 2002-08-06 | Medinox, Inc. | Modified forms of pharmacologically active agents and uses therefor |
| US7638513B2 (en) * | 2004-06-02 | 2009-12-29 | Schering Corporation | Compounds for the treatment of inflammatory disorders |
| EP1630164A1 (en) * | 2004-08-31 | 2006-03-01 | Expotrend Company SA | Pyrazolopyrimidinones as phosphodiesterase inhibitors |
| EP1645288A1 (en) * | 2004-10-07 | 2006-04-12 | CTG Pharma S.r.l. | New nuclear transcription factors regulators |
| CN2757375Y (zh) * | 2004-11-25 | 2006-02-08 | 富士康(昆山)电脑接插件有限公司 | 电子卡连接器 |
| EP1836160A1 (en) * | 2004-12-24 | 2007-09-26 | CTG Pharma S.r.l. | Compounds for treating metabolic syndrome |
| CA2601381A1 (en) | 2005-03-24 | 2006-09-28 | Nycomed Gmbh | 6-thioamide substituted benzimidazoles |
| ITMI20050680A1 (it) * | 2005-04-18 | 2006-10-19 | Ctg Pharma S R L | Nuovi composti anti-infiammatori |
| US7498355B2 (en) | 2005-05-27 | 2009-03-03 | Antibe Therapeutics Inc. | Derivatives of 4- or 5-aminosalicylic acid |
| WO2006125293A1 (en) * | 2005-05-27 | 2006-11-30 | Antibe Therapeutics Inc. | Derivatives of 4- or 5-aminosalicylic acid |
| US20060270635A1 (en) | 2005-05-27 | 2006-11-30 | Wallace John L | Derivatives of 4- or 5-aminosalicylic acid |
| DK2057139T3 (da) * | 2006-07-18 | 2013-11-18 | Antibe Holdings Inc | Hydrogensulfidderivater af non-steroide anti-inflammatoriske lægemidler |
-
2007
- 2007-07-18 DK DK07763931.8T patent/DK2057139T3/da active
- 2007-07-18 BR BRPI0714330-3A patent/BRPI0714330A2/pt not_active IP Right Cessation
- 2007-07-18 JP JP2009519765A patent/JP5529534B2/ja not_active Expired - Fee Related
- 2007-07-18 RU RU2009105491/04A patent/RU2468019C2/ru active
- 2007-07-18 BR BRPI0714466A patent/BRPI0714466B8/pt active IP Right Grant
- 2007-07-18 KR KR1020097001029A patent/KR101450653B1/ko active Active
- 2007-07-18 NZ NZ573996A patent/NZ573996A/en not_active IP Right Cessation
- 2007-07-18 ES ES07763931.8T patent/ES2437223T3/es active Active
- 2007-07-18 CA CA002658429A patent/CA2658429A1/en not_active Abandoned
- 2007-07-18 JP JP2009519769A patent/JP5408719B2/ja active Active
- 2007-07-18 WO PCT/CA2007/001273 patent/WO2008009118A1/en not_active Ceased
- 2007-07-18 MX MX2009000749A patent/MX2009000749A/es active IP Right Grant
- 2007-07-18 US US12/374,273 patent/US8314140B2/en not_active Expired - Fee Related
- 2007-07-18 WO PCT/CA2007/001289 patent/WO2008009127A1/en not_active Ceased
- 2007-07-18 PL PL07763931T patent/PL2057139T3/pl unknown
- 2007-07-18 EP EP07763921.9A patent/EP2041108B1/en not_active Not-in-force
- 2007-07-18 AU AU2007276679A patent/AU2007276679B2/en not_active Ceased
- 2007-07-18 AU AU2007276621A patent/AU2007276621B2/en active Active
- 2007-07-18 KR KR1020097001128A patent/KR101495520B1/ko not_active Expired - Fee Related
- 2007-07-18 MX MX2009000750A patent/MX2009000750A/es active IP Right Grant
- 2007-07-18 EP EP07763931.8A patent/EP2057139B1/en active Active
- 2007-07-18 CA CA2658433A patent/CA2658433C/en active Active
- 2007-07-18 RU RU2009105498/04A patent/RU2465271C2/ru not_active IP Right Cessation
- 2007-07-18 PT PT77639318T patent/PT2057139E/pt unknown
-
2008
- 2008-12-28 IL IL196229A patent/IL196229A/en active IP Right Grant
- 2008-12-28 IL IL196228A patent/IL196228A0/en unknown
-
2009
- 2009-02-17 NO NO20090764A patent/NO20090764L/no not_active Application Discontinuation
- 2009-02-17 NO NO20090763A patent/NO342083B1/no unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2009543813A5 (https=) | ||
| JP2009543811A5 (https=) | ||
| JP5408719B2 (ja) | 非ステロイド系抗炎症薬の硫化水素誘導体 | |
| Li et al. | Anti-inflammatory and gastrointestinal effects of a novel diclofenac derivative | |
| JP5221341B2 (ja) | ４−または５−アミノサリチル酸誘導体 | |
| Zheng et al. | Hydrogen sulfide prodrugs—a review | |
| JP2008542209A5 (https=) | ||
| Wallace et al. | NSAID-induced gastrointestinal damage and the design of GI-sparing NSAIDs | |
| US20100210607A1 (en) | Hydrogen sulfide derivatives of non-steroidal anti-inflammatory drugs | |
| Tozkoparan et al. | Preparation of 5-aryl-3-alkylthio-l, 2, 4-triazoles and corresponding sulfones with antiinflammatory–analgesic activity | |
| CA2827887C (en) | No- and h2s-releasing compounds | |
| JP2009539777A5 (https=) | ||
| Chawla et al. | Chemical modifications of ketoprofen (NSAID) in search of better lead compounds: A Review of literature from 2004-2016 | |
| US7498355B2 (en) | Derivatives of 4- or 5-aminosalicylic acid | |
| US20080207751A1 (en) | Sulindac Derivatives for Treatment of Cancer | |
| WO2006018698A3 (en) | Use of cell-specific conjugates for treatment of inflammatory diseases of the gastrointestinal tract | |
| EP2847161A1 (en) | Compositions and methods for the treatment of diabetes | |
| Abdulhadi et al. | Synthesis of new conjugates of some NSAIDs with sulfonamide as possible mutual prodrugs using tyrosine spacer for colon targeted drug delivery | |
| Raut et al. | Anti-inflammatory, analgesic, ulcerogenic activities of some new non-acidic diclofenac and 1, 3, 4-oxadiazole derivatives in animal models | |
| WO2007093840A3 (en) | Use of cell-specific conjugates for treatment of inflammatory diseases of the gastrointestinal tract | |
| UA108412U (uk) | Спосіб зниження ульцерогенної дії нестероїдних протизапальних препаратів на експериментальних моделях у щурів |