JP2009543567A5 - - Google Patents
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- Publication number
- JP2009543567A5 JP2009543567A5 JP2009519869A JP2009519869A JP2009543567A5 JP 2009543567 A5 JP2009543567 A5 JP 2009543567A5 JP 2009519869 A JP2009519869 A JP 2009519869A JP 2009519869 A JP2009519869 A JP 2009519869A JP 2009543567 A5 JP2009543567 A5 JP 2009543567A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- acid molecule
- stretch
- nucleotides
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002773 nucleotide Substances 0.000 claims 75
- 125000003729 nucleotide group Chemical group 0.000 claims 74
- 150000007523 nucleic acids Chemical class 0.000 claims 73
- 108020004707 nucleic acids Proteins 0.000 claims 68
- 102000039446 nucleic acids Human genes 0.000 claims 68
- 101710088580 Stromal cell-derived factor 1 Proteins 0.000 claims 26
- 102100021669 Stromal cell-derived factor 1 Human genes 0.000 claims 26
- 239000005557 antagonist Substances 0.000 claims 12
- 239000000556 agonist Substances 0.000 claims 9
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 7
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 5
- 201000010099 disease Diseases 0.000 claims 5
- 238000000034 method Methods 0.000 claims 4
- 238000009396 hybridization Methods 0.000 claims 3
- 239000000470 constituent Substances 0.000 claims 2
- 208000035475 disorder Diseases 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 230000001404 mediated effect Effects 0.000 claims 2
- 238000012986 modification Methods 0.000 claims 2
- 230000004048 modification Effects 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 238000012216 screening Methods 0.000 claims 2
- 102100031650 C-X-C chemokine receptor type 4 Human genes 0.000 claims 1
- 101710082513 C-X-C chemokine receptor type 4 Proteins 0.000 claims 1
- 101000617130 Homo sapiens Stromal cell-derived factor 1 Proteins 0.000 claims 1
- 239000013543 active substance Substances 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 238000003745 diagnosis Methods 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 102000043525 human CXCL12 Human genes 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06014957.2 | 2006-07-18 | ||
| EP06014957 | 2006-07-18 | ||
| PCT/EP2007/006387 WO2008009437A2 (en) | 2006-07-18 | 2007-07-18 | Sdf-i binding nucleic acids |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009543567A JP2009543567A (ja) | 2009-12-10 |
| JP2009543567A5 true JP2009543567A5 (cg-RX-API-DMAC7.html) | 2010-09-02 |
| JP5380287B2 JP5380287B2 (ja) | 2014-01-08 |
Family
ID=38947372
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009519869A Active JP5380287B2 (ja) | 2006-07-18 | 2007-07-18 | Ｓｄｆ−１結合核酸 |
Country Status (16)
| Country | Link |
|---|---|
| US (5) | US8314223B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2041282B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP5380287B2 (cg-RX-API-DMAC7.html) |
| KR (2) | KR101561652B1 (cg-RX-API-DMAC7.html) |
| CN (2) | CN101506364B (cg-RX-API-DMAC7.html) |
| AR (1) | AR061929A1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2007276435C1 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0714844B8 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2658267C (cg-RX-API-DMAC7.html) |
| DK (1) | DK2041282T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2663404T3 (cg-RX-API-DMAC7.html) |
| MX (1) | MX2009000656A (cg-RX-API-DMAC7.html) |
| PL (1) | PL2041282T3 (cg-RX-API-DMAC7.html) |
| PT (1) | PT2041282T (cg-RX-API-DMAC7.html) |
| RU (1) | RU2590709C2 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2008009437A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2007276435C1 (en) | 2006-07-18 | 2013-06-13 | TME Pharma AG | SDF-I binding nucleic acids |
| LT2190991T (lt) * | 2007-08-06 | 2020-02-10 | Noxxon Pharma Ag | Sdf-1 surišančios nukleorūgštys ir jų panaudojimas |
| JP5463621B2 (ja) * | 2008-02-27 | 2014-04-09 | ソニー株式会社 | 標的物質の定量方法 |
| AU2009256906A1 (en) * | 2008-06-11 | 2009-12-17 | Bionucleon S.R.L. | Inhibition of HRP-3 using modified oligonucleotides |
| TWI578992B (zh) * | 2009-04-30 | 2017-04-21 | 諾克森製藥股份有限公司 | 與鐵調節激素（ｈｅｐｃｉｄｉｎ）結合之核酸類 |
| WO2012025251A1 (en) * | 2010-08-27 | 2012-03-01 | Noxxon Pharma Ag | Nucleic acids for treatment of chronic complications of diabetes |
| BR112013005664B8 (pt) | 2010-09-09 | 2023-04-25 | Noxxon Pharma Ag | Ácidos nucleicos que se ligam a sdf-1 e uso dos mesmos no tratamento de câncer |
| US20140057970A1 (en) * | 2010-10-29 | 2014-02-27 | Frank Schwobel | Use of Hepcidin Binding Nucleic Acids for Depletion of Hepcidin From the Body |
| ES2940887T3 (es) | 2012-07-13 | 2023-05-12 | Wave Life Sciences Ltd | Método de preparación de oligonucleótidos quirales |
| JP2018505144A (ja) * | 2014-12-17 | 2018-02-22 | キャンサー・リサーチ・テクノロジー・リミテッドＣａｎｃｅｒ Ｒｅｓｅａｒｃｈ Ｔｅｃｈｎｏｌｏｇｙ Ｌｉｍｉｔｅｄ | 抗ｃｘｃｌ１２抗体分子およびその使用 |
| EP3443095A1 (en) * | 2016-04-15 | 2019-02-20 | Noxxon Pharma AG | Method of modulating the number and the distribution of tumor-infiltrating leukocytes in tumors |
| US11221270B2 (en) * | 2018-02-27 | 2022-01-11 | Kevan M Evans | Method and apparatus for detecting slow leaks |
| WO2021178923A1 (en) | 2020-03-06 | 2021-09-10 | Drinksavvy, Inc. | Devices and methods for detecting a target analyte of interest |
| US20230301950A1 (en) | 2020-06-26 | 2023-09-28 | Raqualia Pharma Inc. | Method for selecting cancer patients for whom combination therapy with retinoid and cancer therapeutic agent is effective, and combination medicament with retinoid and cancer therapeutic agent |
| WO2023154452A1 (en) | 2022-02-11 | 2023-08-17 | Waypoint Bio, Inc. | Cellular staining probes for analyte detection |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5567588A (en) | 1990-06-11 | 1996-10-22 | University Research Corporation | Systematic evolution of ligands by exponential enrichment: Solution SELEX |
| US6011020A (en) | 1990-06-11 | 2000-01-04 | Nexstar Pharmaceuticals, Inc. | Nucleic acid ligand complexes |
| US5840867A (en) | 1991-02-21 | 1998-11-24 | Gilead Sciences, Inc. | Aptamer analogs specific for biomolecules |
| AU1435492A (en) * | 1991-02-21 | 1992-09-15 | Gilead Sciences, Inc. | Aptamer specific for biomolecules and method of making |
| US5582981A (en) | 1991-08-14 | 1996-12-10 | Gilead Sciences, Inc. | Method for identifying an oligonucleotide aptamer specific for a target |
| DE69932510T2 (de) * | 1998-03-24 | 2007-02-15 | Chugai Seiyaku K.K. | Vaskularisierungsinhibitoren |
| US6670149B1 (en) * | 1999-03-01 | 2003-12-30 | Millennium Pharmaceuticals, Inc. | TWIK-5 potassium channel nucleic acids and uses therefor |
| US6949243B1 (en) | 1999-11-24 | 2005-09-27 | Schering Corporation | Methods of inhibiting metastasis |
| EP1133988A1 (en) * | 2000-03-11 | 2001-09-19 | Biognostik Gesellschaft für biomolekulare Diagnostik mbH | Mixture comprising an inhibitor or suppressor of a gene and a molecule binding to an expression product of that gene |
| US7468253B2 (en) | 2001-06-07 | 2008-12-23 | Chemocentryx, Inc. | Method for multiple chemokine receptor screening for antagonists using RAM assay |
| DK1417488T3 (da) | 2001-06-07 | 2007-03-05 | Chemocentryx Inc | Cellemigrasionsassay |
| GB0225833D0 (en) | 2002-11-06 | 2002-12-11 | Univ Leeds | Nucleic acid ligands and uses therefor |
| TR201907874T4 (tr) | 2004-09-23 | 2019-06-21 | Arc Medical Devices Inc | Düşük sülfat fukanlar kullanarak fibröz yapışmaları ya da inflamatuar hastalıkları inhibe etmeye yönelik farmasötik kompozisyonlar ve yöntemler. |
| SG157417A1 (en) * | 2004-11-29 | 2009-12-29 | Noxxon Pharma Ag | Vasopressin-binding l-nucleic acids |
| EP2397148A3 (en) | 2006-02-02 | 2012-04-25 | Allergan, Inc. | Compositions and methods for the treatment of ophthalmic disease |
| AU2007276435C1 (en) | 2006-07-18 | 2013-06-13 | TME Pharma AG | SDF-I binding nucleic acids |
| HUE033630T2 (en) | 2006-10-02 | 2017-12-28 | Squibb & Sons Llc | CXCR4 binding human antibodies and their use |
| EP2100140B1 (en) | 2006-11-30 | 2015-05-06 | University Of Virginia Patent Foundation | Methods for diagnosing fibrotic lung diseases |
| LT2190991T (lt) | 2007-08-06 | 2020-02-10 | Noxxon Pharma Ag | Sdf-1 surišančios nukleorūgštys ir jų panaudojimas |
| US20090274687A1 (en) | 2008-05-02 | 2009-11-05 | University Of Miami | Attenuation of hypoxia induced cardiovascular disorders |
-
2007
- 2007-07-18 AU AU2007276435A patent/AU2007276435C1/en active Active
- 2007-07-18 DK DK07786160.7T patent/DK2041282T3/en active
- 2007-07-18 KR KR1020137020754A patent/KR101561652B1/ko active Active
- 2007-07-18 CN CN2007800305243A patent/CN101506364B/zh active Active
- 2007-07-18 AR ARP070103212A patent/AR061929A1/es active IP Right Grant
- 2007-07-18 CA CA2658267A patent/CA2658267C/en active Active
- 2007-07-18 CN CN201310486348.1A patent/CN103555725B/zh active Active
- 2007-07-18 RU RU2009105494/10A patent/RU2590709C2/ru active
- 2007-07-18 EP EP07786160.7A patent/EP2041282B1/en active Active
- 2007-07-18 WO PCT/EP2007/006387 patent/WO2008009437A2/en not_active Ceased
- 2007-07-18 MX MX2009000656A patent/MX2009000656A/es active IP Right Grant
- 2007-07-18 PT PT77861607T patent/PT2041282T/pt unknown
- 2007-07-18 ES ES07786160.7T patent/ES2663404T3/es active Active
- 2007-07-18 JP JP2009519869A patent/JP5380287B2/ja active Active
- 2007-07-18 KR KR1020097000923A patent/KR101466931B1/ko active Active
- 2007-07-18 BR BRPI0714844A patent/BRPI0714844B8/pt active IP Right Grant
- 2007-07-18 PL PL07786160T patent/PL2041282T3/pl unknown
-
2009
- 2009-01-18 US US12/374,311 patent/US8314223B2/en active Active
-
2012
- 2012-10-13 US US13/651,385 patent/US9035038B2/en active Active
-
2015
- 2015-05-06 US US14/705,809 patent/US9822369B2/en active Active
-
2017
- 2017-11-20 US US15/818,618 patent/US20180163207A1/en not_active Abandoned
-
2020
- 2020-11-09 US US17/092,390 patent/US20210139909A1/en not_active Abandoned
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