JP2009542785A5 - - Google Patents

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Publication number
JP2009542785A5
JP2009542785A5 JP2009518952A JP2009518952A JP2009542785A5 JP 2009542785 A5 JP2009542785 A5 JP 2009542785A5 JP 2009518952 A JP2009518952 A JP 2009518952A JP 2009518952 A JP2009518952 A JP 2009518952A JP 2009542785 A5 JP2009542785 A5 JP 2009542785A5
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JP
Japan
Prior art keywords
besylate
salt
salt according
formula
compound
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2009518952A
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English (en)
Japanese (ja)
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JP2009542785A (ja
JP5433413B2 (ja
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Priority claimed from GB0613692A external-priority patent/GB0613692D0/en
Priority claimed from GB0613694A external-priority patent/GB0613694D0/en
Application filed filed Critical
Priority claimed from PCT/GB2007/002565 external-priority patent/WO2008007071A1/en
Publication of JP2009542785A publication Critical patent/JP2009542785A/ja
Publication of JP2009542785A5 publication Critical patent/JP2009542785A5/ja
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Publication of JP5433413B2 publication Critical patent/JP5433413B2/ja
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JP2009518952A 2006-07-10 2007-07-10 短時間作用型ベンゾジアゼピンの塩およびそれらの多形形態 Active JP5433413B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0613692A GB0613692D0 (en) 2006-07-10 2006-07-10 Benzodiazepine salts
GB0613694A GB0613694D0 (en) 2006-07-10 2006-07-10 Benzodiazepine salts
GB0613694.9 2006-07-10
GB0613692.3 2006-07-10
PCT/GB2007/002565 WO2008007071A1 (en) 2006-07-10 2007-07-10 Short-acting benzodiazepine salts and their polymorphic forms

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2012235328A Division JP5785923B2 (ja) 2006-07-10 2012-10-25 短時間作用型ベンゾジアゼピンの塩およびそれらの多形形態

Publications (3)

Publication Number Publication Date
JP2009542785A JP2009542785A (ja) 2009-12-03
JP2009542785A5 true JP2009542785A5 (enExample) 2011-07-28
JP5433413B2 JP5433413B2 (ja) 2014-03-05

Family

ID=38535381

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2009518952A Active JP5433413B2 (ja) 2006-07-10 2007-07-10 短時間作用型ベンゾジアゼピンの塩およびそれらの多形形態
JP2012235328A Active JP5785923B2 (ja) 2006-07-10 2012-10-25 短時間作用型ベンゾジアゼピンの塩およびそれらの多形形態

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2012235328A Active JP5785923B2 (ja) 2006-07-10 2012-10-25 短時間作用型ベンゾジアゼピンの塩およびそれらの多形形態

Country Status (17)

Country Link
US (7) US9193730B2 (enExample)
EP (1) EP2081921B1 (enExample)
JP (2) JP5433413B2 (enExample)
KR (3) KR20150081370A (enExample)
CN (3) CN103288834B (enExample)
AT (1) ATE480532T1 (enExample)
AU (1) AU2007274054B2 (enExample)
BR (1) BRPI0714886B8 (enExample)
CA (1) CA2657347C (enExample)
DE (1) DE602007009128D1 (enExample)
DK (1) DK2081921T3 (enExample)
MX (1) MX2009000404A (enExample)
PL (1) PL2081921T3 (enExample)
PT (1) PT2081921E (enExample)
RU (1) RU2470935C2 (enExample)
SI (1) SI2081921T1 (enExample)
WO (1) WO2008007071A1 (enExample)

Families Citing this family (22)

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GB0613693D0 (en) 2006-07-10 2006-08-16 Cenes Ltd Benzodiazepine salts (3)
DK2081921T3 (da) 2006-07-10 2011-01-03 Paion Uk Ltd Korttidsvirkende benzodiazepinsalte og deres polymorfe former
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EP2450039A1 (en) 2010-11-08 2012-05-09 PAION UK Ltd. Dosing regimen for sedation with CNS 7056 (Remimazolam)
PT2852389T (pt) 2012-05-22 2017-12-13 Paion Uk Ltd Composições que compreendem benzodiazepinas de ação rápida
BR112015004477A8 (pt) * 2012-08-31 2019-08-27 Paion Uk Ltd uso de composto na preparação de um sedativo e composição farmacêutica
AR094963A1 (es) 2013-03-04 2015-09-09 Ono Pharmaceutical Co Reacción de oxidación excelente en el índice de conversión
PL3162804T3 (pl) * 2014-07-23 2020-04-30 Jiangsu Nhwaluokang Pharmaceutical Research And Development Co., Ltd. Nowa pochodna benzodiazepiny i jej zastosowanie
US20170081954A1 (en) * 2015-09-23 2017-03-23 Tesco Corporation Pipe joint location detection system and method
CN110511224A (zh) * 2016-04-08 2019-11-29 四川科伦药物研究院有限公司 苯并二氮杂*衍生物的盐及其晶体形式、制备方法和用途
WO2017178663A1 (en) * 2016-04-14 2017-10-19 Paion Uk Limited Orally inhaled and nasal benzodiazepines
CN108503644B (zh) * 2016-12-09 2019-06-14 成都倍特药业有限公司 一种苯并二氮杂*衍生物的氢溴酸盐及其制备方法和用途
EP3580219B1 (en) 2017-02-09 2022-04-13 Assia Chemical Industries Ltd. Process for the preparation of remimazolam and solid state forms of remimazolam salts
CN108948018B (zh) * 2017-05-17 2021-03-30 四川科伦博泰生物医药股份有限公司 苯并二氮*衍生物及其盐和相关晶体形式、制备方法和用途
US11708368B2 (en) 2018-02-13 2023-07-25 Jiangsu Nhwaluokang Pharmaceutical Research And Development Co., Ltd. Crystal form of ethyl (S)-3-(8-bromo-1-methyl-6-(pyridin-2-yl)-4H-benzo[f]imidazo[1,2-a][1,4]diazepin-4-yl)propanoate hydrochloride
CN110398514B (zh) * 2018-04-24 2023-04-28 恒天纤维集团有限公司 一种快速判断纤维素胶液中金属杂质含量的方法
ES2803099B2 (es) 2019-07-22 2021-11-08 Moehs Iberica Sl Procedimiento de obtención de besilato de remimazolam amorfo
CN114478535B (zh) * 2020-10-23 2024-02-09 成都苑东生物制药股份有限公司 一种苯磺酸瑞马唑仑ii晶型的制备方法
WO2023037237A1 (en) * 2021-09-09 2023-03-16 Wavelength Enterprises Ltd Process for the preparation of remimazolam
EP4504731A1 (en) 2022-04-08 2025-02-12 Fresenius Kabi Oncology Ltd An improved process for the preparation of remimazolam
CN115448927A (zh) * 2022-10-20 2022-12-09 重庆瑞泊莱医药科技有限公司 一种氢溴酸依匹斯汀晶型ii及其制备方法
WO2025052259A1 (en) 2023-09-05 2025-03-13 Reena Patel Ready to use compositions of remimazolam

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PT2852389T (pt) 2012-05-22 2017-12-13 Paion Uk Ltd Composições que compreendem benzodiazepinas de ação rápida
BR112015004477A8 (pt) 2012-08-31 2019-08-27 Paion Uk Ltd uso de composto na preparação de um sedativo e composição farmacêutica
CN107659350A (zh) 2012-09-28 2018-02-02 华为技术有限公司 信道状态信息进程处理方法、网络设备和用户设备
AR094963A1 (es) 2013-03-04 2015-09-09 Ono Pharmaceutical Co Reacción de oxidación excelente en el índice de conversión

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