JP2009541443A - 尿失禁及び関連疾患の治療のためのフリバンセリン - Google Patents
尿失禁及び関連疾患の治療のためのフリバンセリン Download PDFInfo
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- JP2009541443A JP2009541443A JP2009517186A JP2009517186A JP2009541443A JP 2009541443 A JP2009541443 A JP 2009541443A JP 2009517186 A JP2009517186 A JP 2009517186A JP 2009517186 A JP2009517186 A JP 2009517186A JP 2009541443 A JP2009541443 A JP 2009541443A
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- pharmaceutically acceptable
- solvate
- hydrate
- acid addition
- active ingredient
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Classifications
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/095—Oxytocins; Vasopressins; Related peptides
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
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- Bioinformatics & Cheminformatics (AREA)
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- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Endocrinology (AREA)
- Zoology (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06116393 | 2006-06-30 | ||
| PCT/EP2007/056400 WO2008000760A1 (en) | 2006-06-30 | 2007-06-27 | Flibanserin for the treatment of urinary incontinence and related diseases |
Publications (2)
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| JP2009541443A true JP2009541443A (ja) | 2009-11-26 |
| JP2009541443A5 JP2009541443A5 (https=) | 2010-08-12 |
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| JP (1) | JP2009541443A (https=) |
| AT (1) | ATE456369T1 (https=) |
| CA (1) | CA2654798C (https=) |
| DE (1) | DE602007004615D1 (https=) |
| ES (1) | ES2336719T3 (https=) |
| WO (1) | WO2008000760A1 (https=) |
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| US10675280B2 (en) | 2001-10-20 | 2020-06-09 | Sprout Pharmaceuticals, Inc. | Treating sexual desire disorders with flibanserin |
| UA78974C2 (en) | 2001-10-20 | 2007-05-10 | Boehringer Ingelheim Pharma | Use of flibanserin for treating disorders of sexual desire |
| US20040048877A1 (en) * | 2002-05-22 | 2004-03-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pharmaceutical compositions containing flibanserin |
| US20050239798A1 (en) * | 2004-04-22 | 2005-10-27 | Boehringer Ingelheim Pharmaceuticals, Inc. | Method for the treatment of premenstrual and other female sexual disorders |
| ES2646326T3 (es) * | 2005-08-03 | 2017-12-13 | Sprout Pharmaceuticals, Inc. | Uso de flibanserina en el tratamiento de la obesidad |
| CA2626134C (en) | 2005-10-29 | 2013-12-24 | Boehringer Ingelheim International Gmbh | Benzimidazolone derivatives for the treatment of premenstrual and other female sexual disorders |
| US20070105869A1 (en) * | 2005-11-08 | 2007-05-10 | Stephane Pollentier | Use of flibanserin for the treatment of pre-menopausal sexual desire disorders |
| BRPI0712039A2 (pt) * | 2006-05-09 | 2011-12-20 | Boehringer Ingelheim Int | uso de flibanserina para o tratamento de distúrbios de desejo sexual pós-menopausa |
| JP2009541443A (ja) | 2006-06-30 | 2009-11-26 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 尿失禁及び関連疾患の治療のためのフリバンセリン |
| CL2007002214A1 (es) | 2006-08-14 | 2008-03-07 | Boehringer Ingelheim Int | Composicion farmaceutica en la forma de comprimido, donde al menos la longitud del comprimido en el estado anterior de la aplicacion es al menos 7/12 del diametro pilorico del paciente y despues de ingerirlo en estado alimentado, la longitud del comp |
| EP2054041A2 (en) | 2006-08-14 | 2009-05-06 | Boehringer Ingelheim International GmbH | Formulations of flibanserin and method for manufacturing the same |
| IL197129A (en) | 2006-08-25 | 2014-08-31 | Boehringer Ingelheim Int | Controlled release system and method for production |
| JP2010513390A (ja) * | 2006-12-20 | 2010-04-30 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 混合セロトニン受容体親和性を有する硫酸化ベンズイミダゾロン誘導体 |
| WO2008090742A1 (ja) * | 2007-01-23 | 2008-07-31 | National University Corporation Hokkaido University | 眼疾患モデル用非ヒト動物 |
| CL2008002693A1 (es) * | 2007-09-12 | 2009-10-16 | Boehringer Ingelheim Int | Uso de flibanserina para el tratamiento de sintomas vasomotores seleccionados de sofocos, sudores nocturnos, cambios de estado de animo e irritabilidad |
| CA2686480A1 (en) | 2008-12-15 | 2010-06-15 | Boehringer Ingelheim International Gmbh | New salts |
| US8778998B2 (en) | 2009-04-10 | 2014-07-15 | Auspex Pharmaceuticals, Inc. | Biphenyl-3-carboxylic acid modulators of beta-3-adrenoreceptor |
| WO2010123999A2 (en) * | 2009-04-21 | 2010-10-28 | Auspex Pharmaceuticals, Inc. | 1-methylpyrazole modulators of substance p, calcitonin gene-related peptide, adrenergic receptor, and/or 5-ht receptor |
| EP4019634A4 (en) * | 2019-08-13 | 2024-04-03 | Universidade de Santiago de Compostela | COMPOUNDS AND METHODS FOR TREATING CANCER |
Citations (2)
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| WO2003035072A1 (en) * | 2001-10-20 | 2003-05-01 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Use of flibanserin in the treatment of sexual disorders |
| WO2003097058A1 (en) * | 2002-05-22 | 2003-11-27 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | New pharmaceutical compositions containing flibanserin polymorph a |
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- 2007-06-27 WO PCT/EP2007/056400 patent/WO2008000760A1/en not_active Ceased
- 2007-06-27 DE DE602007004615T patent/DE602007004615D1/de active Active
- 2007-06-27 AT AT07765655T patent/ATE456369T1/de active
- 2007-06-27 CA CA2654798A patent/CA2654798C/en not_active Expired - Fee Related
- 2007-06-27 ES ES07765655T patent/ES2336719T3/es active Active
- 2007-06-27 US US12/306,878 patent/US20090312242A1/en not_active Abandoned
- 2007-06-27 EP EP07765655A patent/EP2037927B1/en not_active Not-in-force
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2012
- 2012-11-19 US US13/680,722 patent/US20130203671A1/en not_active Abandoned
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2015
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Also Published As
| Publication number | Publication date |
|---|---|
| US20090312242A1 (en) | 2009-12-17 |
| EP2037927B1 (en) | 2010-01-27 |
| ES2336719T3 (es) | 2010-04-15 |
| US20180071282A1 (en) | 2018-03-15 |
| WO2008000760A1 (en) | 2008-01-03 |
| ATE456369T1 (de) | 2010-02-15 |
| CA2654798A1 (en) | 2008-01-03 |
| US9763936B2 (en) | 2017-09-19 |
| EP2037927A1 (en) | 2009-03-25 |
| US10004731B2 (en) | 2018-06-26 |
| US20130203671A1 (en) | 2013-08-08 |
| US20160051545A1 (en) | 2016-02-25 |
| CA2654798C (en) | 2015-01-13 |
| DE602007004615D1 (de) | 2010-03-18 |
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