JP2009540012A5 - - Google Patents

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Publication number
JP2009540012A5
JP2009540012A5 JP2009515619A JP2009515619A JP2009540012A5 JP 2009540012 A5 JP2009540012 A5 JP 2009540012A5 JP 2009515619 A JP2009515619 A JP 2009515619A JP 2009515619 A JP2009515619 A JP 2009515619A JP 2009540012 A5 JP2009540012 A5 JP 2009540012A5
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JP
Japan
Prior art keywords
diamine
pyrimidine
dimethylamino
propyl
ethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2009515619A
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English (en)
Japanese (ja)
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JP5306190B2 (ja
JP2009540012A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2007/071073 external-priority patent/WO2007146977A1/en
Publication of JP2009540012A publication Critical patent/JP2009540012A/ja
Publication of JP2009540012A5 publication Critical patent/JP2009540012A5/ja
Application granted granted Critical
Publication of JP5306190B2 publication Critical patent/JP5306190B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2009515619A 2006-06-15 2007-06-13 ２−アニリノ−４−アミノアルキレンアミノピリミジン Expired - Fee Related JP5306190B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US81387506P 2006-06-15 2006-06-15
US60/813,875 2006-06-15
PCT/US2007/071073 WO2007146977A1 (en) 2006-06-15 2007-06-13 2-anilino-4-aminoalkyleneaminopyrimidines

Publications (3)

Publication Number Publication Date
JP2009540012A JP2009540012A (ja) 2009-11-19
JP2009540012A5 true JP2009540012A5 (https=) 2010-07-29
JP5306190B2 JP5306190B2 (ja) 2013-10-02

Family

ID=38611102

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009515619A Expired - Fee Related JP5306190B2 (ja) 2006-06-15 2007-06-13 ２−アニリノ−４−アミノアルキレンアミノピリミジン

Country Status (15)

Country Link
US (2) US20070293525A1 (https=)
EP (1) EP2032543A1 (https=)
JP (1) JP5306190B2 (https=)
KR (1) KR20090023698A (https=)
CN (1) CN101506176A (https=)
AR (1) AR062822A1 (https=)
AU (1) AU2007257701A1 (https=)
CA (1) CA2655315A1 (https=)
CL (1) CL2007001748A1 (https=)
IL (1) IL195865A0 (https=)
MX (1) MX2008016007A (https=)
RU (1) RU2008152193A (https=)
TW (1) TW200815368A (https=)
WO (1) WO2007146977A1 (https=)
ZA (1) ZA200809945B (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2008152195A (ru) * 2006-06-15 2010-07-20 БЕРИНГЕР ИНГЕЛЬХАЙМ ИНТЕРНАЦИОНАЛЬ ГмбХ (DE) 2-анилино-4-(гетероциклил)аминопиримидины, как ингибиторы протеинкиназы с-альфа
PL2252300T3 (pl) 2008-02-22 2017-04-28 Rigel Pharmaceuticals, Inc. Zastosowanie 2,4-pirymidynodiamin do leczenia miażdżycy
EP2483406A2 (en) 2009-09-30 2012-08-08 President and Fellows of Harvard College Methods for modulation of autophagy through the modulation of autophagy-inhibiting gene products
US8735417B2 (en) * 2009-12-17 2014-05-27 Merck Sharp & Dohme Corp. Aminopyrimidines as Syk inhibitors
PT2576541T (pt) 2010-06-04 2016-07-08 Hoffmann La Roche Derivados de aminopirimidina como moduladores de lrrk2
HRP20172006T1 (hr) 2010-11-10 2018-02-09 Genentech, Inc. Derivati pirazol-aminopiridina kao lrrk2-modulatori
KR101664106B1 (ko) * 2014-09-11 2016-10-10 한국화학연구원 폴리믹신 b 화합물을 포함하는 심혈관 질환의 예방 및 치료용 약학적 조성물
JP2018527895A (ja) 2015-06-29 2018-09-27 リージェンツ オブ ザ ユニバーシティ オブ ミネソタ 抗−ａｐｏｂｅｃ３抗体並びにその製造及び使用方法
KR101876514B1 (ko) * 2016-11-08 2018-07-10 한국화학연구원 신규한 피리미딘화합물, 이의 제조방법 및 이를 유효성분으로 함유하는 암 및 염증질환의 예방 또는 치료용 약학적 조성물
CN109516959A (zh) * 2018-12-03 2019-03-26 陕西师范大学 2-芳氨基-4-取代嘧啶类衍生物及其在制备抗肿瘤药物中的应用

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DE833651C (de) 1943-11-02 1952-03-10 Ici Ltd Verfahren zur Herstellung von neuen Pyrimidinabkoemmlingen
GB587550A (en) 1944-09-25 1947-04-29 Francis Henry Swinden Curd New pyrimidine compounds
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FR2244520B1 (https=) 1973-07-06 1977-02-04 Ugine Kuhlmann
GB9523675D0 (en) 1995-11-20 1996-01-24 Celltech Therapeutics Ltd Chemical compounds
EP0945442A1 (en) 1998-03-27 1999-09-29 Janssen Pharmaceutica N.V. Trisubstituted pyrimidine derivatives
CZ299380B6 (cs) 1998-03-27 2008-07-09 Janssen Pharmaceutica N. V. Pyrimidinová sloucenina, použití této slouceniny pro prípravu léciva, farmaceutický prostredek tutoslouceninu obsahující, zpusob prípravy tohoto prostredku a uvedené slouceniny a kombinace a produktuvedenou slouceninu obsahující
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BRPI0413018B8 (pt) 2003-07-30 2021-05-25 Rigel Pharmaceuticals Inc composto, e, uso de um composto
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RU2008152195A (ru) * 2006-06-15 2010-07-20 БЕРИНГЕР ИНГЕЛЬХАЙМ ИНТЕРНАЦИОНАЛЬ ГмбХ (DE) 2-анилино-4-(гетероциклил)аминопиримидины, как ингибиторы протеинкиназы с-альфа

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