JP2009538832A5 - - Google Patents
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- JP2009538832A5 JP2009538832A5 JP2009511536A JP2009511536A JP2009538832A5 JP 2009538832 A5 JP2009538832 A5 JP 2009538832A5 JP 2009511536 A JP2009511536 A JP 2009511536A JP 2009511536 A JP2009511536 A JP 2009511536A JP 2009538832 A5 JP2009538832 A5 JP 2009538832A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- acetaldehyde
- cysteine
- stomach
- film
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000000203 mixture Substances 0.000 claims description 49
- IKHGUXGNUITLKF-UHFFFAOYSA-N Acetaldehyde Chemical compound CC=O IKHGUXGNUITLKF-UHFFFAOYSA-N 0.000 claims 44
- 150000001875 compounds Chemical class 0.000 claims 24
- 210000002784 stomach Anatomy 0.000 claims 13
- 229940078469 dl- cysteine Drugs 0.000 claims 6
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims 6
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims 6
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims 6
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims 6
- 210000002966 serum Anatomy 0.000 claims 6
- 238000011282 treatment Methods 0.000 claims 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 5
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims 4
- 108010047320 Pepsinogen A Proteins 0.000 claims 4
- 239000002775 capsule Substances 0.000 claims 4
- 239000003795 chemical substances by application Substances 0.000 claims 4
- 210000001072 colon Anatomy 0.000 claims 4
- 239000000945 filler Substances 0.000 claims 4
- 238000004519 manufacturing process Methods 0.000 claims 4
- 235000012054 meals Nutrition 0.000 claims 4
- 229920000642 polymer Polymers 0.000 claims 4
- VVNCNSJFMMFHPL-VKHMYHEASA-N D-penicillamine Chemical compound CC(C)(S)[C@@H](N)C(O)=O VVNCNSJFMMFHPL-VKHMYHEASA-N 0.000 claims 3
- 229960001639 penicillamine Drugs 0.000 claims 3
- 150000003839 salts Chemical class 0.000 claims 3
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims 2
- PWKSKIMOESPYIA-UHFFFAOYSA-N 2-acetamido-3-sulfanylpropanoic acid Chemical compound CC(=O)NC(CS)C(O)=O PWKSKIMOESPYIA-UHFFFAOYSA-N 0.000 claims 2
- 208000002310 Achlorhydria Diseases 0.000 claims 2
- NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonia chloride Chemical compound [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 claims 2
- XUJNEKJLAYXESH-UWTATZPHSA-N D-Cysteine Chemical compound SC[C@@H](N)C(O)=O XUJNEKJLAYXESH-UWTATZPHSA-N 0.000 claims 2
- 229930195710 D‐cysteine Natural products 0.000 claims 2
- 239000001856 Ethyl cellulose Substances 0.000 claims 2
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 claims 2
- 229920003152 Eudragit® RS polymer Polymers 0.000 claims 2
- 108090001072 Gastricsin Proteins 0.000 claims 2
- 208000007882 Gastritis Diseases 0.000 claims 2
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 claims 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims 2
- PWKSKIMOESPYIA-BYPYZUCNSA-N L-N-acetyl-Cysteine Chemical compound CC(=O)N[C@@H](CS)C(O)=O PWKSKIMOESPYIA-BYPYZUCNSA-N 0.000 claims 2
- ZUKPVRWZDMRIEO-VKHMYHEASA-N L-cysteinylglycine Chemical compound SC[C@H]([NH3+])C(=O)NCC([O-])=O ZUKPVRWZDMRIEO-VKHMYHEASA-N 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 102000034255 Pepsinogen C Human genes 0.000 claims 2
- 208000005718 Stomach Neoplasms Diseases 0.000 claims 2
- 229960004308 acetylcysteine Drugs 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 2
- 230000000112 colonic effect Effects 0.000 claims 2
- XVOYSCVBGLVSOL-UHFFFAOYSA-N cysteic acid Chemical compound OC(=O)C(N)CS(O)(=O)=O XVOYSCVBGLVSOL-UHFFFAOYSA-N 0.000 claims 2
- 230000007812 deficiency Effects 0.000 claims 2
- 238000003745 diagnosis Methods 0.000 claims 2
- 238000009792 diffusion process Methods 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 2
- 235000019325 ethyl cellulose Nutrition 0.000 claims 2
- 229920001249 ethyl cellulose Polymers 0.000 claims 2
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 claims 2
- 238000009472 formulation Methods 0.000 claims 2
- 210000004211 gastric acid Anatomy 0.000 claims 2
- 206010017758 gastric cancer Diseases 0.000 claims 2
- 230000002496 gastric effect Effects 0.000 claims 2
- 239000007903 gelatin capsule Substances 0.000 claims 2
- 239000008187 granular material Substances 0.000 claims 2
- 230000000968 intestinal effect Effects 0.000 claims 2
- 210000000936 intestine Anatomy 0.000 claims 2
- 239000000463 material Substances 0.000 claims 2
- 239000011159 matrix material Substances 0.000 claims 2
- 231100000252 nontoxic Toxicity 0.000 claims 2
- 230000003000 nontoxic effect Effects 0.000 claims 2
- 229920006254 polymer film Polymers 0.000 claims 2
- 201000011549 stomach cancer Diseases 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- 230000002459 sustained effect Effects 0.000 claims 2
- 125000003396 thiol group Chemical group [H]S* 0.000 claims 2
- 239000011782 vitamin Substances 0.000 claims 2
- 229940088594 vitamin Drugs 0.000 claims 2
- QIJRTFXNRTXDIP-UHFFFAOYSA-N (1-carboxy-2-sulfanylethyl)azanium;chloride;hydrate Chemical compound O.Cl.SCC(N)C(O)=O QIJRTFXNRTXDIP-UHFFFAOYSA-N 0.000 claims 1
- MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 claims 1
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 claims 1
- IAICFWDJMWEXAO-UHFFFAOYSA-N 2-(2-sulfanylethylamino)acetic acid Chemical compound OC(=O)CNCCS IAICFWDJMWEXAO-UHFFFAOYSA-N 0.000 claims 1
- 208000010444 Acidosis Diseases 0.000 claims 1
- 239000004475 Arginine Substances 0.000 claims 1
- 208000004300 Atrophic Gastritis Diseases 0.000 claims 1
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical class [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims 1
- VYZAMTAEIAYCRO-UHFFFAOYSA-N Chromium Chemical compound [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 claims 1
- OELDIVRKHTYFNG-WDSKDSINSA-N Cys-Val Chemical compound CC(C)[C@@H](C(O)=O)NC(=O)[C@@H](N)CS OELDIVRKHTYFNG-WDSKDSINSA-N 0.000 claims 1
- RWSOTUBLDIXVET-UHFFFAOYSA-N Dihydrogen sulfide Chemical class S RWSOTUBLDIXVET-UHFFFAOYSA-N 0.000 claims 1
- 108010016626 Dipeptides Proteins 0.000 claims 1
- 229920003136 Eudragit® L polymer Polymers 0.000 claims 1
- 229920003137 Eudragit® S polymer Polymers 0.000 claims 1
- 208000036495 Gastritis atrophic Diseases 0.000 claims 1
- 108010024636 Glutathione Proteins 0.000 claims 1
- 239000004471 Glycine Substances 0.000 claims 1
- FFFHZYDWPBMWHY-UHFFFAOYSA-N HOMOCYSTEINE Chemical compound OC(=O)C(N)CCS FFFHZYDWPBMWHY-UHFFFAOYSA-N 0.000 claims 1
- 206010019133 Hangover Diseases 0.000 claims 1
- 206010019375 Helicobacter infections Diseases 0.000 claims 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- XUJNEKJLAYXESH-REOHCLBHSA-N L-Cysteine Chemical compound SC[C@H](N)C(O)=O XUJNEKJLAYXESH-REOHCLBHSA-N 0.000 claims 1
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 claims 1
- LEVWYRKDKASIDU-IMJSIDKUSA-N L-cystine Chemical compound [O-]C(=O)[C@@H]([NH3+])CSSC[C@H]([NH3+])C([O-])=O LEVWYRKDKASIDU-IMJSIDKUSA-N 0.000 claims 1
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 claims 1
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 claims 1
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 claims 1
- 239000004472 Lysine Substances 0.000 claims 1
- 208000001145 Metabolic Syndrome Diseases 0.000 claims 1
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 claims 1
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 claims 1
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 claims 1
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 claims 1
- JZRWCGZRTZMZEH-UHFFFAOYSA-N Thiamine Natural products CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N JZRWCGZRTZMZEH-UHFFFAOYSA-N 0.000 claims 1
- 229930003779 Vitamin B12 Natural products 0.000 claims 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims 1
- 201000000690 abdominal obesity-metabolic syndrome Diseases 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 230000007950 acidosis Effects 0.000 claims 1
- 208000026545 acidosis disease Diseases 0.000 claims 1
- 125000002252 acyl group Chemical group 0.000 claims 1
- 125000003277 amino group Chemical group 0.000 claims 1
- 235000019270 ammonium chloride Nutrition 0.000 claims 1
- 229940069428 antacid Drugs 0.000 claims 1
- 239000003159 antacid agent Substances 0.000 claims 1
- 230000001458 anti-acid effect Effects 0.000 claims 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims 1
- 229960002685 biotin Drugs 0.000 claims 1
- 235000020958 biotin Nutrition 0.000 claims 1
- 239000011616 biotin Substances 0.000 claims 1
- 125000004432 carbon atom Chemical group C* 0.000 claims 1
- 229940107218 chromium Drugs 0.000 claims 1
- 229910052804 chromium Inorganic materials 0.000 claims 1
- 239000011651 chromium Substances 0.000 claims 1
- 208000016644 chronic atrophic gastritis Diseases 0.000 claims 1
- AGVAZMGAQJOSFJ-WZHZPDAFSA-M cobalt(2+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(1r,2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2 Chemical compound [Co+2].N#[C-].[N-]([C@@H]1[C@H](CC(N)=O)[C@@]2(C)CCC(=O)NC[C@@H](C)OP(O)(=O)O[C@H]3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)\C2=C(C)/C([C@H](C\2(C)C)CCC(N)=O)=N/C/2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O AGVAZMGAQJOSFJ-WZHZPDAFSA-M 0.000 claims 1
- UFULAYFCSOUIOV-UHFFFAOYSA-N cysteamine Chemical compound NCCS UFULAYFCSOUIOV-UHFFFAOYSA-N 0.000 claims 1
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 claims 1
- 229960002433 cysteine Drugs 0.000 claims 1
- 235000018417 cysteine Nutrition 0.000 claims 1
- 229960001305 cysteine hydrochloride Drugs 0.000 claims 1
- 108010016616 cysteinylglycine Proteins 0.000 claims 1
- 229960003067 cystine Drugs 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000035475 disorder Diseases 0.000 claims 1
- VHJLVAABSRFDPM-QWWZWVQMSA-N dithiothreitol Chemical compound SC[C@@H](O)[C@H](O)CS VHJLVAABSRFDPM-QWWZWVQMSA-N 0.000 claims 1
- FSXVSUSRJXIJHB-UHFFFAOYSA-M ethyl prop-2-enoate;methyl 2-methylprop-2-enoate;trimethyl-[2-(2-methylprop-2-enoyloxy)ethyl]azanium;chloride Chemical compound [Cl-].CCOC(=O)C=C.COC(=O)C(C)=C.CC(=C)C(=O)OCC[N+](C)(C)C FSXVSUSRJXIJHB-UHFFFAOYSA-M 0.000 claims 1
- 229960000304 folic acid Drugs 0.000 claims 1
- 239000011724 folic acid Substances 0.000 claims 1
- 235000019152 folic acid Nutrition 0.000 claims 1
- 208000021302 gastroesophageal reflux disease Diseases 0.000 claims 1
- 210000001035 gastrointestinal tract Anatomy 0.000 claims 1
- 229910052739 hydrogen Inorganic materials 0.000 claims 1
- 239000001257 hydrogen Substances 0.000 claims 1
- 229910052742 iron Inorganic materials 0.000 claims 1
- 235000010445 lecithin Nutrition 0.000 claims 1
- 239000000787 lecithin Substances 0.000 claims 1
- 229940067606 lecithin Drugs 0.000 claims 1
- WPBNNNQJVZRUHP-UHFFFAOYSA-L manganese(2+);methyl n-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate;n-[2-(sulfidocarbothioylamino)ethyl]carbamodithioate Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S.COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC WPBNNNQJVZRUHP-UHFFFAOYSA-L 0.000 claims 1
- 125000005395 methacrylic acid group Chemical group 0.000 claims 1
- 229930182817 methionine Natural products 0.000 claims 1
- 229960004452 methionine Drugs 0.000 claims 1
- 235000006109 methionine Nutrition 0.000 claims 1
- 229960003512 nicotinic acid Drugs 0.000 claims 1
- 239000011664 nicotinic acid Substances 0.000 claims 1
- 235000001968 nicotinic acid Nutrition 0.000 claims 1
- 239000011148 porous material Substances 0.000 claims 1
- 230000000291 postprandial effect Effects 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 239000011669 selenium Substances 0.000 claims 1
- 229910052711 selenium Inorganic materials 0.000 claims 1
- DUIOPKIIICUYRZ-UHFFFAOYSA-N semicarbazide Chemical compound NNC(N)=O DUIOPKIIICUYRZ-UHFFFAOYSA-N 0.000 claims 1
- 229960001153 serine Drugs 0.000 claims 1
- 235000004400 serine Nutrition 0.000 claims 1
- HRZFUMHJMZEROT-UHFFFAOYSA-L sodium disulfite Chemical compound [Na+].[Na+].[O-]S(=O)S([O-])(=O)=O HRZFUMHJMZEROT-UHFFFAOYSA-L 0.000 claims 1
- 229940001584 sodium metabisulfite Drugs 0.000 claims 1
- 235000010262 sodium metabisulphite Nutrition 0.000 claims 1
- 125000001174 sulfone group Chemical group 0.000 claims 1
- 238000013268 sustained release Methods 0.000 claims 1
- 239000012730 sustained-release form Substances 0.000 claims 1
- 239000011721 thiamine Substances 0.000 claims 1
- 235000019157 thiamine Nutrition 0.000 claims 1
- 229960003495 thiamine Drugs 0.000 claims 1
- KYMBYSLLVAOCFI-UHFFFAOYSA-N thiamine Chemical compound CC1=C(CCO)SCN1CC1=CN=C(C)N=C1N KYMBYSLLVAOCFI-UHFFFAOYSA-N 0.000 claims 1
- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 claims 1
- 229960000344 thiamine hydrochloride Drugs 0.000 claims 1
- 235000019190 thiamine hydrochloride Nutrition 0.000 claims 1
- 239000011747 thiamine hydrochloride Substances 0.000 claims 1
- 239000011715 vitamin B12 Substances 0.000 claims 1
- 235000019163 vitamin B12 Nutrition 0.000 claims 1
- 239000011701 zinc Substances 0.000 claims 1
- 229910052725 zinc Inorganic materials 0.000 claims 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 235000013361 beverage Nutrition 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80212006P | 2006-05-22 | 2006-05-22 | |
| FI20060501A FI20060501L (fi) | 2006-05-22 | 2006-05-22 | Koostumus ja menetelmä asetaldehydin sitomiseksi vatsassa |
| PCT/FI2007/050287 WO2007135241A2 (en) | 2006-05-22 | 2007-05-22 | Composition and method for binding acetaldehyde in stomach |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013161521A Division JP6178657B2 (ja) | 2006-05-22 | 2013-08-02 | 胃内でアセトアルデヒドを結合するための組成物および方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009538832A JP2009538832A (ja) | 2009-11-12 |
| JP2009538832A5 true JP2009538832A5 (enExample) | 2010-07-08 |
Family
ID=38436750
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009511537A Expired - Fee Related JP5394235B2 (ja) | 2006-05-22 | 2007-05-22 | アセトアルデヒドを結合するための食品用組成物 |
| JP2009511536A Withdrawn JP2009538832A (ja) | 2006-05-22 | 2007-05-22 | 胃内でアセトアルデヒドを結合するための組成物および方法 |
| JP2013098512A Withdrawn JP2013177413A (ja) | 2006-05-22 | 2013-05-08 | アセトアルデヒドを結合するための食品用組成物 |
| JP2013161521A Active JP6178657B2 (ja) | 2006-05-22 | 2013-08-02 | 胃内でアセトアルデヒドを結合するための組成物および方法 |
| JP2016147411A Withdrawn JP2016196500A (ja) | 2006-05-22 | 2016-07-27 | 胃内でアセトアルデヒドを結合するための組成物および方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009511537A Expired - Fee Related JP5394235B2 (ja) | 2006-05-22 | 2007-05-22 | アセトアルデヒドを結合するための食品用組成物 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013098512A Withdrawn JP2013177413A (ja) | 2006-05-22 | 2013-05-08 | アセトアルデヒドを結合するための食品用組成物 |
| JP2013161521A Active JP6178657B2 (ja) | 2006-05-22 | 2013-08-02 | 胃内でアセトアルデヒドを結合するための組成物および方法 |
| JP2016147411A Withdrawn JP2016196500A (ja) | 2006-05-22 | 2016-07-27 | 胃内でアセトアルデヒドを結合するための組成物および方法 |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US8758812B2 (enExample) |
| EP (2) | EP2049097B1 (enExample) |
| JP (5) | JP5394235B2 (enExample) |
| KR (4) | KR20130099217A (enExample) |
| CN (2) | CN101668522B (enExample) |
| CY (1) | CY1123875T1 (enExample) |
| DK (1) | DK2049097T3 (enExample) |
| EA (2) | EA019832B1 (enExample) |
| ES (1) | ES2845635T3 (enExample) |
| FI (1) | FI20060501L (enExample) |
| HU (1) | HUE052428T2 (enExample) |
| LT (1) | LT2049097T (enExample) |
| PL (1) | PL2049097T3 (enExample) |
| PT (1) | PT2049097T (enExample) |
| SI (1) | SI2049097T1 (enExample) |
| WO (2) | WO2007135242A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110171296A1 (en) * | 2000-10-30 | 2011-07-14 | Biohit Oyj | Method and preparation for binding acetaldehyde in saliva, the stomach and the large intestine |
| US20070077297A1 (en) | 2004-09-30 | 2007-04-05 | Scolr Pharma, Inc. | Modified release ibuprofen dosage form |
| FI20060501L (fi) * | 2006-05-22 | 2007-11-23 | Biohit Oyj | Koostumus ja menetelmä asetaldehydin sitomiseksi vatsassa |
| JP5496616B2 (ja) * | 2009-11-18 | 2014-05-21 | フロイント産業株式会社 | 大腸ドラッグデリバリーシステム製剤 |
| DE102011001768A1 (de) | 2011-04-04 | 2012-10-04 | Gunnar Frank | Präparat oder Nahrungsergänzungsmittel |
| FI20115377A7 (fi) * | 2011-04-18 | 2012-10-19 | Biohit Oyj | Ylempien hengitys- ja ruoansulatuselinten mikrobi-infektioihin liittyvissä tiloissa käytettäväksi tarkoitettuja lääketieteellisiä tuotteita |
| ITMI20120847A1 (it) * | 2012-05-16 | 2013-11-17 | Labomar S R L | Formulazione per sostanze a bassa biodisponibilità. |
| FI129157B (en) * | 2012-05-28 | 2021-08-13 | Biohit Oyj | Composition for use in reducing the incidence of or preventing severe headaches |
| US20160022621A1 (en) * | 2013-03-12 | 2016-01-28 | Biohit Oyj | Composition for oral administration for binding aldehydes in the gastrointestinal tract |
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2006
- 2006-05-22 FI FI20060501A patent/FI20060501L/fi not_active Application Discontinuation
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2007
- 2007-05-22 US US12/301,925 patent/US8758812B2/en active Active
- 2007-05-22 JP JP2009511537A patent/JP5394235B2/ja not_active Expired - Fee Related
- 2007-05-22 EA EA200802360A patent/EA019832B1/ru unknown
- 2007-05-22 EP EP07730774.2A patent/EP2049097B1/en active Active
- 2007-05-22 WO PCT/FI2007/050288 patent/WO2007135242A1/en not_active Ceased
- 2007-05-22 EA EA200802361A patent/EA021063B1/ru unknown
- 2007-05-22 HU HUE07730774A patent/HUE052428T2/hu unknown
- 2007-05-22 LT LTEP07730774.2T patent/LT2049097T/lt unknown
- 2007-05-22 US US12/301,906 patent/US20090253793A1/en not_active Abandoned
- 2007-05-22 DK DK07730774.2T patent/DK2049097T3/da active
- 2007-05-22 EP EP07730775A patent/EP2034982A1/en not_active Withdrawn
- 2007-05-22 KR KR1020137019534A patent/KR20130099217A/ko not_active Ceased
- 2007-05-22 PL PL07730774T patent/PL2049097T3/pl unknown
- 2007-05-22 KR KR1020087031178A patent/KR20090015986A/ko not_active Ceased
- 2007-05-22 PT PT77307742T patent/PT2049097T/pt unknown
- 2007-05-22 KR KR1020137002597A patent/KR20130020733A/ko not_active Ceased
- 2007-05-22 CN CN200780026340.XA patent/CN101668522B/zh active Active
- 2007-05-22 JP JP2009511536A patent/JP2009538832A/ja not_active Withdrawn
- 2007-05-22 KR KR1020087031142A patent/KR20090030272A/ko not_active Ceased
- 2007-05-22 SI SI200732169T patent/SI2049097T1/sl unknown
- 2007-05-22 CN CNA2007800273492A patent/CN101489545A/zh active Pending
- 2007-05-22 ES ES07730774T patent/ES2845635T3/es active Active
- 2007-05-22 WO PCT/FI2007/050287 patent/WO2007135241A2/en not_active Ceased
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2013
- 2013-05-08 JP JP2013098512A patent/JP2013177413A/ja not_active Withdrawn
- 2013-08-02 JP JP2013161521A patent/JP6178657B2/ja active Active
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2016
- 2016-07-27 JP JP2016147411A patent/JP2016196500A/ja not_active Withdrawn
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2021
- 2021-01-27 CY CY20211100066T patent/CY1123875T1/el unknown
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