JP2009538331A - 抑うつ障害のための治療 - Google Patents

抑うつ障害のための治療 Download PDF

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Publication number
JP2009538331A
JP2009538331A JP2009512244A JP2009512244A JP2009538331A JP 2009538331 A JP2009538331 A JP 2009538331A JP 2009512244 A JP2009512244 A JP 2009512244A JP 2009512244 A JP2009512244 A JP 2009512244A JP 2009538331 A JP2009538331 A JP 2009538331A
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JP
Japan
Prior art keywords
antagonist
disorder
antidepressant
way
iloperidone
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Pending
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JP2009512244A
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English (en)
Japanese (ja)
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JP2009538331A5 (https=
Inventor
カート， ディー． ウルフギャング，
マイケル， エイチ． ポリメロポラス，
Original Assignee
ヴァンダ ファーマシューティカルズ インコーポレイテッド
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Publication of JP2009538331A publication Critical patent/JP2009538331A/ja
Publication of JP2009538331A5 publication Critical patent/JP2009538331A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401—Proline; Derivatives thereof, e.g. captopril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP2009512244A 2006-05-22 2007-05-21 抑うつ障害のための治療 Pending JP2009538331A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US74786106P 2006-05-22 2006-05-22
PCT/US2007/069373 WO2007137227A1 (en) 2006-05-22 2007-05-21 Treatment for depressive disorders

Publications (2)

Publication Number Publication Date
JP2009538331A true JP2009538331A (ja) 2009-11-05
JP2009538331A5 JP2009538331A5 (https=) 2010-09-02

Family

ID=38723631

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009512244A Pending JP2009538331A (ja) 2006-05-22 2007-05-21 抑うつ障害のための治療

Country Status (11)

Country Link
US (1) US20090306137A1 (https=)
EP (1) EP2029136A4 (https=)
JP (1) JP2009538331A (https=)
KR (1) KR20090029200A (https=)
AU (1) AU2007253684A1 (https=)
BR (1) BRPI0711872A2 (https=)
CA (1) CA2652416A1 (https=)
MX (1) MX2008014843A (https=)
RU (1) RU2008150624A (https=)
WO (1) WO2007137227A1 (https=)
ZA (1) ZA200809528B (https=)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015510893A (ja) * 2012-03-14 2015-04-13 ヴァンダ ファーマシューティカルズ インコーポレイテッド 精神障害の治療における使用のためのイロペリドン代謝物
JP2015516979A (ja) * 2012-04-23 2015-06-18 ホルスボールマッシュマイヤー ニューロケミー ゲーエムベーハーＨｏｌｓｂｏｅｒｍａｓｃｈｍｅｙｅｒ Ｎｅｕｒｏｃｈｅｍｉｅ Ｇｍｂｈ Ｃｒｈ過剰活性を有する患者の治療に用いるためのｃｒｈｒ１アンタゴニスト
JP2015517569A (ja) * 2012-05-24 2015-06-22 エルティーディー“バレンタ−インテレクト”Ｌｔｄ Ｖａｌｅｎｔａ−Ｉｎｔｅｌｌｅｋｔ 精神的障害、行動障害および認知障害の予防および治療のための医薬組成物
JP2015522541A (ja) * 2012-05-18 2015-08-06 ヴァンダ ファーマシューティカルズ インコーポレイテッド （１Ｒ−ｔｒａｎｓ）−Ｎ−［［２−（２，３−ジヒドロ−４−ベンゾフラニル）シクロプロピル］メチル］プロパンアミドの代謝物
US10837062B2 (en) 2013-06-17 2020-11-17 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Method for predicting a treatment response to a CRHR1 antagonist and/or a V1B antagonist in a patient with depressive and/or anxiety symptoms
US10857129B2 (en) 2012-06-15 2020-12-08 B.R.A.H.M.S Gmbh V1B receptor antagonist for use in the treatment of patients having an elevated AVP level and/or an elevated copeptin level

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9162980B2 (en) 2009-01-09 2015-10-20 Board Of Regents Of The University Of Texas System Anti-depression compounds
US9962368B2 (en) 2009-01-09 2018-05-08 Board Of Regents Of The University Of Texas System Pro-neurogenic compounds
US8362277B2 (en) 2009-01-09 2013-01-29 Board Of Regents Of The University Of Texas System Pro-neurogenic compounds
US9095572B2 (en) 2009-01-09 2015-08-04 Board Of Regents Of The University Of Texas System Pro-neurogenic compounds
EP2385829B1 (en) 2009-01-09 2018-08-01 Board of Regents of the University of Texas System Pro-neurogenic compounds
MX2012007365A (es) * 2009-12-23 2012-08-15 Lupin Ltd Composiciones farmaceuticas de liberacion lenta de iloperidona.
FR2956031B1 (fr) * 2010-02-11 2012-03-02 Servier Lab Utilisation de l'agomelatine pour l'obtention de medicaments destines au traitement du trouble obsessionnel compulsif (toc)
UY33869A (es) 2011-01-17 2012-08-31 Takeda Pharmaceutical Comprimido dispersable por vía oral
US8426461B2 (en) 2011-01-17 2013-04-23 Takeda Pharmaceutical Company Limited Orally dispersible tablet
FR2978916B1 (fr) * 2011-08-10 2013-07-26 Servier Lab Composition pharmaceutique solide pour administration buccale d'agomelatine
RU2465895C1 (ru) * 2011-09-08 2012-11-10 Государственное образовательное учреждение высшего профессионального образования "Мордовский государственный университет им. Н.П. Огарева" Способ лечения депрессивного невроза
WO2013054582A1 (en) * 2011-10-14 2013-04-18 Takeda Pharmaceutical Company Limited Orally dispersible tablet
PE20141906A1 (es) * 2012-03-12 2014-12-05 Janssen Pharmaceutica Nv Esketamina para el tratamiento de la depresion refractaria al tratamiento o resistente al tratamiento
AU2013305591B2 (en) 2012-08-24 2017-04-13 Board Of Regents Of The University Of Texas System Pro-neurogenic compounds
UA107653U (uk) 2012-10-01 2016-06-24 Общєство С Огранічєнной Отвєтствєнностью "Валєнта-Інтєллєкт" Композиція лікарських засобів для лікування та профілактики поведінкових, психічних та когнітивних розладів
WO2014120936A2 (en) 2013-01-30 2014-08-07 Pharmorx Therapeutics, Inc. Treatments for depression and other diseases with a low dose agent
PE20200404A1 (es) 2013-03-15 2020-02-26 Janssen Pharmaceutica Nv Composicion farmaceutica de clorhidrato de s-ketamina
KR101484405B1 (ko) * 2013-08-14 2015-01-19 서울대학교산학협력단 Ｎｉｎｊｕｒｉｎ１ 결핍 유래의 강박증 예방 또는 치료용 약학적 조성물
WO2015070234A2 (en) 2013-11-11 2015-05-14 Board Of Regents Of The University Of Texas System Neuroprotective compounds and use thereof
WO2015070237A1 (en) 2013-11-11 2015-05-14 Board Of Regents Of The University Of Texas System Neuroprotective chemicals and methods for identifying and using same
WO2015112642A1 (en) 2014-01-21 2015-07-30 Neurocrine Biosciences, Inc. Crf1 receptor antagonists for the treatment of congenital adrenal hyperplasia
RU2571546C1 (ru) * 2014-07-14 2015-12-20 Государственное бюджетное образовательное учреждение высшего профессионального образования "Воронежский государственный медицинский университет имени Н.Н. Бурденко" Министерства здравоохранения Российской Федерации Способ дифференцированной диагностики и терапии синдрома ночной еды
CN106714789A (zh) 2014-08-13 2017-05-24 詹森药业有限公司 用于治疗抑郁症的方法
CN107208133A (zh) 2014-09-15 2017-09-26 詹森药业有限公司 用于治疗抑郁症的Val66Met (SNPrs6265)基因型特异性给药方案和方法
US9744209B2 (en) 2015-01-30 2017-08-29 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9750785B2 (en) 2015-01-30 2017-09-05 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9744239B2 (en) 2015-01-30 2017-08-29 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9687526B2 (en) 2015-01-30 2017-06-27 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9925233B2 (en) 2015-01-30 2018-03-27 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9937223B2 (en) 2015-01-30 2018-04-10 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US20160332962A1 (en) 2015-05-13 2016-11-17 Janssen Pharmaceutica Nv (s)-csa salt of s-ketamine, (r)-csa salt of s-ketamine and processes for the preparation of s-ketamine
US20200009081A1 (en) 2017-09-13 2020-01-09 Janssen Pharmaceutica N.V. Delivery Of Esketamine For The Treatment Of Depression
MX2020006650A (es) 2017-12-22 2020-11-06 Janssen Pharmaceuticals Inc Esketamina para el tratamiento de la depresión.
PL3505157T3 (pl) 2017-12-29 2022-04-11 Celon Pharma S.A. Kompozycja ketaminy w postaci suchego proszku do podawania dopłucnego w leczeniu depresji opornej na leczenie
CA3121920A1 (en) 2018-12-07 2020-06-11 Neurocrine Biosciences, Inc. Crf1 receptor antagonist, pharmaceutical formulations and solid forms thereof for the treatment of congenital adrenal hyperplasia
MX2021010683A (es) 2019-03-05 2021-12-10 Janssen Pharmaceuticals Inc Esketamina para el tratamiento de la depresión.
JP7623365B2 (ja) 2019-09-27 2025-01-28 ニューロクライン バイオサイエンシーズ，インコーポレイテッド Ｃｒｆ受容体アンタゴニストおよび使用方法
JP7541765B2 (ja) 2019-11-27 2024-08-29 諾羅瑞韋株式会社 うつ病を治療するためのシクロセリン及びリチウム併用療法
MX2022009528A (es) * 2020-02-04 2022-11-14 Mindset Pharma Inc Derivados de 3-pirrolidina-indol como agentes psicodélicos serotoninérgicos para el tratamiento de trastornos del snc.

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002308801A (ja) * 2001-03-01 2002-10-23 Pfizer Prod Inc うつ病、強迫疾患および精神病の組み合わせ治療
WO2004010932A2 (en) * 2002-07-30 2004-02-05 Peter Migaly Combination therapy for depression, prevention of suicide, and varous medical and psychiatric conditions
JP2004517112A (ja) * 2001-01-02 2004-06-10 ファルマシア・アンド・アップジョン・カンパニー 新規薬物コンビネーション
JP2004517959A (ja) * 2001-02-05 2004-06-17 ノバルティス アクチエンゲゼルシャフト イロペリドンの新規使用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4804663A (en) * 1985-03-27 1989-02-14 Janssen Pharmaceutica N.V. 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles
US5158952A (en) * 1988-11-07 1992-10-27 Janssen Pharmaceutica N.V. 3-[2-[4-(6-fluoro-1,2-benzisoxozol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9 tetrahydro-9-hydroxy-2-methyl-4H-pyrido [1,2-a]pyrimidin-4-one, compositions and method of use
US5776963A (en) 1989-05-19 1998-07-07 Hoechst Marion Roussel, Inc. 3-(heteroaryl)-1- (2,3-dihydro-1h-isoindol-2-yl)alkyl!pyrrolidines and 3-(heteroaryl)-1- (2,3-dihydro-1h-indol-1-yl)alkyl!pyrrolidines and related compounds and their therapeutic untility
US5364866A (en) * 1989-05-19 1994-11-15 Hoechst-Roussel Pharmaceuticals, Inc. Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analetics
AU2927392A (en) 1991-11-01 1993-06-07 National-Standard Company Age resistant solder coatings
DK1425272T3 (da) 2001-08-31 2011-11-21 Novartis Ag Optiske isomerer af en iloperidon-metabolit
ES2436439T3 (es) 2001-10-30 2014-01-02 Novartis Ag Formulaciones de medicamento de liberación lenta de iloperidona con un polímero
SI1458888T1 (sl) 2001-12-10 2011-07-29 Novartis Ag Metode zdravljenja psihoze in shizofrenije na osnovi polimorfizmov gena cntf
GB0216416D0 (en) 2002-07-15 2002-08-21 Novartis Ag Organic compounds
US6831077B2 (en) * 2002-07-25 2004-12-14 Comprehensive Neuroscience, Inc. Augmentation of atypical antipsychotic agent pharmacotherapy with chromium supplementation
US20050203130A1 (en) * 2003-12-02 2005-09-15 Erik Buntinx Use of D4 and 5-HT2A antagonists, inverse agonists or partial agonists
EP1799865B1 (en) * 2004-09-30 2012-06-06 Vanda Pharmaceuticals Inc. Methods for the administration of iloperidone

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004517112A (ja) * 2001-01-02 2004-06-10 ファルマシア・アンド・アップジョン・カンパニー 新規薬物コンビネーション
JP2004517959A (ja) * 2001-02-05 2004-06-17 ノバルティス アクチエンゲゼルシャフト イロペリドンの新規使用
JP2002308801A (ja) * 2001-03-01 2002-10-23 Pfizer Prod Inc うつ病、強迫疾患および精神病の組み合わせ治療
WO2004010932A2 (en) * 2002-07-30 2004-02-05 Peter Migaly Combination therapy for depression, prevention of suicide, and varous medical and psychiatric conditions

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
JPN6013034468; Ｋａｌｋｍａｎ　ＨＯ　ｅｔ　ａｌ．: 'Ｆｕｎｃｔｉｏｎａｌ　ｃｈａｒａｃｔｅｒｉｚａｔｉｏｎ　ｏｆ　ｔｈｅ　ｎｏｖｅｌ　ａｎｔｉｐｓｙｃｈｏｔｉｃ　ｉｌｏｐｅｒｉｄｏｎｅ　ａｔ　ｈｕｍａｎ　Ｄ２，　Ｄ３，　ａｌｐｈａ　２Ｃ，　５-ＨＴ６，' Ｌｉｆｅ　Ｓｃｉ． Ｖｏｌ．７３　Ｎｏ．９, 20030718, ｐｐ．１１５１-１１５９ *
JPN6013034469; Ｋａｌｋｍａｎ　ＨＯ　ｅｔ　ａｌ．: 'Ｅｘｔｅｎｄｅｄ　ｒａｄｉｏｌｉｇａｎｄ　ｂｉｎｄｉｎｇ　ｐｒｏｆｉｌｅ　ｏｆ　ｉｌｏｐｅｒｉｄｏｎｅ：　ａ　ｂｒｏａｄ　ｓｐｅｃｔｒｕｍ　ｄｏｐａｍｉｎｅ／ｓｅｒｏｔｏｎｉｎ／ｎｏｒｅｐｉｎｅｐｈｒ' Ｎｅｕｒｏｐｓｙｃｈｏｐｈａｒｍａｃｏｌｏｇｙ． Ｖｏｌ．２５　Ｎｏ．６, 200112, ｐｐ．９０４-９１４ *
JPN6013034472; Ｒｉｃｈｅｌｓｏｎ　Ｅ　ａｎｄ　Ｓｏｕｄｅｒ　Ｔ: 'Ｂｉｎｄｉｎｇ　ｏｆ　ａｎｔｉｐｓｙｃｈｏｔｉｃ　ｄｒｕｇｓ　ｔｏ　ｈｕｍａｎ　ｂｒａｉｎ　ｒｅｃｅｐｔｏｒｓ　ｆｏｃｕｓ　ｏｎ　ｎｅｗｅｒ　ｇｅｎｅｒａｔｉｏｎ　ｃｏｍｐｏｕｎｄｓ．' Ｌｉｆｅ　Ｓｃｉ． Ｖｏｌ．６８　Ｎｏ．１, 20001224, ｐｐ．２９-３９ *
JPN6013034474; Ｋｏｎｇｓａｍｕｔ　Ｓ　ｅｔ　ａｌ．: 'Ｉｌｏｐｅｒｉｄｏｎｅ　ｂｉｎｄｉｎｇ　ｔｏ　ｈｕｍａｎ　ａｎｄ　ｒａｔ　ｄｏｐａｍｉｎｅ　ａｎｄ　５-ＨＴ　ｒｅｃｅｐｔｏｒｓ．' Ｅｕｒ　Ｊ　Ｐｈａｒｍａｃｏｌ． Ｖｏｌ．３１７　Ｎｏ．２-３, 19961219, ｐｐ．４１７-４２３ *

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015510893A (ja) * 2012-03-14 2015-04-13 ヴァンダ ファーマシューティカルズ インコーポレイテッド 精神障害の治療における使用のためのイロペリドン代謝物
JP2017061506A (ja) * 2012-03-14 2017-03-30 ヴァンダ ファーマシューティカルズ インコーポレイテッド 精神障害の治療における使用のためのイロペリドン代謝物
US10874659B2 (en) 2012-03-14 2020-12-29 Vanda Pharmaceuticals Inc. Iloperidone metabolite for use in the treatment of psychiatric disorders
JP2015516979A (ja) * 2012-04-23 2015-06-18 ホルスボールマッシュマイヤー ニューロケミー ゲーエムベーハーＨｏｌｓｂｏｅｒｍａｓｃｈｍｅｙｅｒ Ｎｅｕｒｏｃｈｅｍｉｅ Ｇｍｂｈ Ｃｒｈ過剰活性を有する患者の治療に用いるためのｃｒｈｒ１アンタゴニスト
JP2015522541A (ja) * 2012-05-18 2015-08-06 ヴァンダ ファーマシューティカルズ インコーポレイテッド （１Ｒ−ｔｒａｎｓ）−Ｎ−［［２−（２，３−ジヒドロ−４−ベンゾフラニル）シクロプロピル］メチル］プロパンアミドの代謝物
JP2015517569A (ja) * 2012-05-24 2015-06-22 エルティーディー“バレンタ−インテレクト”Ｌｔｄ Ｖａｌｅｎｔａ−Ｉｎｔｅｌｌｅｋｔ 精神的障害、行動障害および認知障害の予防および治療のための医薬組成物
US10857129B2 (en) 2012-06-15 2020-12-08 B.R.A.H.M.S Gmbh V1B receptor antagonist for use in the treatment of patients having an elevated AVP level and/or an elevated copeptin level
US10837062B2 (en) 2013-06-17 2020-11-17 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Method for predicting a treatment response to a CRHR1 antagonist and/or a V1B antagonist in a patient with depressive and/or anxiety symptoms

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BRPI0711872A2 (pt) 2011-12-06
ZA200809528B (en) 2009-11-25
CA2652416A1 (en) 2007-11-29
WO2007137227A1 (en) 2007-11-29
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