JP2009536745A5 - - Google Patents
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- JP2009536745A5 JP2009536745A5 JP2009510116A JP2009510116A JP2009536745A5 JP 2009536745 A5 JP2009536745 A5 JP 2009536745A5 JP 2009510116 A JP2009510116 A JP 2009510116A JP 2009510116 A JP2009510116 A JP 2009510116A JP 2009536745 A5 JP2009536745 A5 JP 2009536745A5
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- activator compound
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- 150000001875 compounds Chemical class 0.000 claims description 40
- 125000004429 atom Chemical group 0.000 claims description 13
- 125000004435 hydrogen atom Chemical class [H]* 0.000 claims description 12
- 125000000217 alkyl group Chemical group 0.000 claims description 7
- 125000003277 amino group Chemical group 0.000 claims description 7
- 125000003118 aryl group Chemical group 0.000 claims description 7
- 125000004432 carbon atom Chemical group C* 0.000 claims description 7
- 125000005843 halogen group Chemical group 0.000 claims description 6
- 125000005647 linker group Chemical group 0.000 claims description 6
- 125000003342 alkenyl group Chemical group 0.000 claims description 5
- 125000000304 alkynyl group Chemical group 0.000 claims description 5
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims description 5
- 125000003710 aryl alkyl group Chemical group 0.000 claims description 4
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 claims description 4
- 125000003147 glycosyl group Chemical group 0.000 claims description 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 3
- 125000005496 phosphonium group Chemical group 0.000 claims description 3
- 125000001453 quaternary ammonium group Chemical group 0.000 claims description 3
- 229910052710 silicon Inorganic materials 0.000 claims description 3
- 125000003808 silyl group Chemical group [H][Si]([H])([H])[*] 0.000 claims description 3
- 125000003396 thiol group Chemical group [H]S* 0.000 claims description 3
- 239000012190 activator Substances 0.000 claims 24
- 230000009870 specific binding Effects 0.000 claims 19
- 239000012491 analyte Substances 0.000 claims 13
- 238000003556 assay Methods 0.000 claims 13
- 239000000463 material Substances 0.000 claims 13
- 239000007787 solid Substances 0.000 claims 13
- -1 peroxide compounds Chemical class 0.000 claims 9
- 102000039446 nucleic acids Human genes 0.000 claims 7
- 108020004707 nucleic acids Proteins 0.000 claims 7
- 150000007523 nucleic acids Chemical class 0.000 claims 7
- 239000002245 particle Substances 0.000 claims 6
- 102000004190 Enzymes Human genes 0.000 claims 4
- 108090000790 Enzymes Proteins 0.000 claims 4
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims 4
- 229910052739 hydrogen Inorganic materials 0.000 claims 4
- 239000001257 hydrogen Substances 0.000 claims 4
- 125000004433 nitrogen atom Chemical group N* 0.000 claims 4
- 125000004430 oxygen atom Chemical group O* 0.000 claims 4
- 102000013415 peroxidase activity proteins Human genes 0.000 claims 4
- 108040007629 peroxidase activity proteins Proteins 0.000 claims 4
- 125000004437 phosphorous atom Chemical group 0.000 claims 4
- 239000004033 plastic Substances 0.000 claims 4
- 125000004434 sulfur atom Chemical group 0.000 claims 4
- 230000027455 binding Effects 0.000 claims 3
- 125000001033 ether group Chemical group 0.000 claims 3
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 claims 2
- KXDHJXZQYSOELW-UHFFFAOYSA-N Carbamic acid Chemical group NC(O)=O KXDHJXZQYSOELW-UHFFFAOYSA-N 0.000 claims 2
- 102000014914 Carrier Proteins Human genes 0.000 claims 2
- HJCUTNIGJHJGCF-UHFFFAOYSA-N acridan acid Natural products C1=CC=C2CC3=CC=CC=C3NC2=C1 HJCUTNIGJHJGCF-UHFFFAOYSA-N 0.000 claims 2
- 125000004450 alkenylene group Chemical group 0.000 claims 2
- 125000004183 alkoxy alkyl group Chemical group 0.000 claims 2
- 125000003545 alkoxy group Chemical group 0.000 claims 2
- 125000002947 alkylene group Chemical group 0.000 claims 2
- 125000003368 amide group Chemical group 0.000 claims 2
- 125000000320 amidine group Chemical group 0.000 claims 2
- 125000000732 arylene group Chemical group 0.000 claims 2
- 125000004104 aryloxy group Chemical group 0.000 claims 2
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims 2
- 108091008324 binding proteins Proteins 0.000 claims 2
- VPKDCDLSJZCGKE-UHFFFAOYSA-N carbodiimide group Chemical group N=C=N VPKDCDLSJZCGKE-UHFFFAOYSA-N 0.000 claims 2
- 125000005392 carboxamide group Chemical group NC(=O)* 0.000 claims 2
- 125000004181 carboxyalkyl group Chemical group 0.000 claims 2
- 239000001913 cellulose Substances 0.000 claims 2
- 229920002678 cellulose Polymers 0.000 claims 2
- 239000000084 colloidal system Substances 0.000 claims 2
- 230000000295 complement effect Effects 0.000 claims 2
- 125000004093 cyano group Chemical group *C#N 0.000 claims 2
- 125000000664 diazo group Chemical group [N-]=[N+]=[*] 0.000 claims 2
- 125000002228 disulfide group Chemical group 0.000 claims 2
- 125000004185 ester group Chemical group 0.000 claims 2
- CEIPQQODRKXDSB-UHFFFAOYSA-N ethyl 3-(6-hydroxynaphthalen-2-yl)-1H-indazole-5-carboximidate dihydrochloride Chemical group Cl.Cl.C1=C(O)C=CC2=CC(C3=NNC4=CC=C(C=C43)C(=N)OCC)=CC=C21 CEIPQQODRKXDSB-UHFFFAOYSA-N 0.000 claims 2
- 229910052736 halogen Inorganic materials 0.000 claims 2
- 150000002367 halogens Chemical class 0.000 claims 2
- OAKJQQAXSVQMHS-UHFFFAOYSA-N hydrazine group Chemical group NN OAKJQQAXSVQMHS-UHFFFAOYSA-N 0.000 claims 2
- 125000005462 imide group Chemical group 0.000 claims 2
- 125000000879 imine group Chemical group 0.000 claims 2
- 239000004816 latex Substances 0.000 claims 2
- 229920000126 latex Polymers 0.000 claims 2
- 239000006249 magnetic particle Substances 0.000 claims 2
- 239000002184 metal Substances 0.000 claims 2
- 125000002081 peroxide group Chemical group 0.000 claims 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 2
- 229920000642 polymer Polymers 0.000 claims 2
- 229910052711 selenium Chemical group 0.000 claims 2
- 239000000377 silicon dioxide Substances 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- 125000001273 sulfonato group Chemical group [O-]S(*)(=O)=O 0.000 claims 2
- 125000001174 sulfone group Chemical group 0.000 claims 2
- 125000003375 sulfoxide group Chemical group 0.000 claims 2
- 150000007970 thio esters Chemical group 0.000 claims 2
- 125000000101 thioether group Chemical group 0.000 claims 2
- UMGDCJDMYOKAJW-UHFFFAOYSA-N thiourea group Chemical group NC(=S)N UMGDCJDMYOKAJW-UHFFFAOYSA-N 0.000 claims 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N urea group Chemical group NC(=O)N XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims 2
- DUMVSAKGDUQHMK-UHFFFAOYSA-N 9,10-dihydroacridine-1-sulfonamide Chemical compound N1C2=CC=CC=C2CC2=C1C=CC=C2S(=O)(=O)N DUMVSAKGDUQHMK-UHFFFAOYSA-N 0.000 claims 1
- 102000009027 Albumins Human genes 0.000 claims 1
- 108010088751 Albumins Proteins 0.000 claims 1
- 102000004506 Blood Proteins Human genes 0.000 claims 1
- 108010017384 Blood Proteins Proteins 0.000 claims 1
- 108010090804 Streptavidin Proteins 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 125000005227 alkyl sulfonate group Chemical group 0.000 claims 1
- 150000008064 anhydrides Chemical class 0.000 claims 1
- 150000004982 aromatic amines Chemical class 0.000 claims 1
- 150000001543 aryl boronic acids Chemical class 0.000 claims 1
- 230000000903 blocking effect Effects 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000003623 enhancer Substances 0.000 claims 1
- 150000002148 esters Chemical class 0.000 claims 1
- 125000000468 ketone group Chemical group 0.000 claims 1
- 150000002576 ketones Chemical class 0.000 claims 1
- 150000002978 peroxides Chemical class 0.000 claims 1
- 150000002989 phenols Chemical class 0.000 claims 1
- 150000004713 phosphodiesters Chemical group 0.000 claims 1
- 238000000159 protein binding assay Methods 0.000 claims 1
- 239000000758 substrate Substances 0.000 claims 1
- 230000005281 excited state Effects 0.000 description 2
- 0 C*(C([C@]12)=C(*)C(*)=C(*)C1N(*)c1c(*)c(*)c(*=[I-])c(*)c1C2=C(*)S=*)I Chemical compound C*(C([C@]12)=C(*)C(*)=C(*)C1N(*)c1c(*)c(*)c(*=[I-])c(*)c1C2=C(*)S=*)I 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- GPTXWRGISTZRIO-UHFFFAOYSA-N chlorquinaldol Chemical compound ClC1=CC(Cl)=C(O)C2=NC(C)=CC=C21 GPTXWRGISTZRIO-UHFFFAOYSA-N 0.000 description 1
- 230000005284 excitation Effects 0.000 description 1
- 239000000543 intermediate Substances 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 125000002347 octyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 125000000962 organic group Chemical group 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 125000001424 substituent group Chemical group 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US79883906P | 2006-05-09 | 2006-05-09 | |
| US11/799,895 US7732153B2 (en) | 2006-05-09 | 2007-05-03 | Nonseparation assay methods |
| PCT/US2007/068327 WO2007133988A1 (en) | 2006-05-09 | 2007-05-07 | Nonseparation assay methods |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009536745A JP2009536745A (ja) | 2009-10-15 |
| JP2009536745A5 true JP2009536745A5 (enExample) | 2013-05-02 |
Family
ID=38685587
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009510116A Pending JP2009536745A (ja) | 2006-05-09 | 2007-05-07 | 非分離アッセイ方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (4) | US7732153B2 (enExample) |
| EP (1) | EP2027453B1 (enExample) |
| JP (1) | JP2009536745A (enExample) |
| KR (2) | KR20090042203A (enExample) |
| CN (1) | CN102175851B (enExample) |
| AU (1) | AU2007249527B2 (enExample) |
| IL (1) | IL194892A (enExample) |
| MX (2) | MX338982B (enExample) |
| WO (1) | WO2007133988A1 (enExample) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7682839B2 (en) * | 2005-03-14 | 2010-03-23 | Lumigen, Inc. | Methods using novel chemiluminescent labels |
| US7732153B2 (en) * | 2006-05-09 | 2010-06-08 | Beckman Coulter, Inc. | Nonseparation assay methods |
| WO2009062027A1 (en) * | 2007-11-07 | 2009-05-14 | Beckman Coulter, Inc. | Nonseparation assay methods using peroxide generating enzymes |
| CN101470115A (zh) * | 2007-12-28 | 2009-07-01 | 万积成 | 同时检测10种食品微生物的装置及筛查诊断方法 |
| MX2011009019A (es) * | 2009-02-27 | 2011-09-29 | Beckman Coulter Inc | Ensayos homogeneos de fase de solucion. |
| MX2011009020A (es) * | 2009-02-27 | 2011-09-29 | Beckman Coulter Inc | Ensayo sin separacion con inhibidores de señal selectiva. |
| US20110097723A1 (en) * | 2009-09-19 | 2011-04-28 | Qun Liu | Methods and reagents for analyte detection |
| CN102081102B (zh) * | 2009-12-23 | 2013-09-18 | 刘萍 | 化学发光底物液 |
| CN103293303B (zh) * | 2012-03-01 | 2016-12-14 | 上海鑫谱生物科技有限公司 | 一种荧光分析方法和装置 |
| KR101580360B1 (ko) * | 2013-05-22 | 2015-12-28 | 김성천 | 연자성미세구조물을 이용한 리간드의 스크리닝 시스템 및 그 용도 |
| US20160033497A1 (en) * | 2014-08-02 | 2016-02-04 | Tianxin Wang | Luminescence methods and reagents for analyte detection |
| US10494665B2 (en) | 2014-08-20 | 2019-12-03 | Huawei Yang | Test kit and method for testing target nucleic acid in sample |
| CN104535560B (zh) * | 2015-01-13 | 2017-02-01 | 同昕生物技术（北京）有限公司 | 一种酶促化学发光底物液 |
| CN105067809A (zh) * | 2015-07-27 | 2015-11-18 | 青岛汉唐生物科技有限公司 | 用于快速检测病原体抗体的酶免渗滤法、检测用的试剂盒及其制备方法 |
| AU2016358205B2 (en) * | 2015-11-20 | 2022-01-06 | Anteo Technologies Pty Ltd | Method of controlled competitive exchange |
| EP3176580A1 (en) * | 2015-12-01 | 2017-06-07 | Roche Diagnostics GmbH | Method for reduction of interferences in immunoassays |
| CN106483293A (zh) * | 2016-10-13 | 2017-03-08 | 广州华弘生物科技有限公司 | He4a 临床免疫检测试剂盒及其制备方法 |
| CN107058584A (zh) * | 2017-06-07 | 2017-08-18 | 浙江殷欣生物技术有限公司 | 一种核酸杂交化学发光检测方法 |
| CN108414736B (zh) * | 2018-02-08 | 2020-11-17 | 江苏三联生物工程有限公司 | 一种利用化学发光增强子修饰的抗体检测目标物的方法 |
| GB2571763A (en) * | 2018-03-08 | 2019-09-11 | Sumitomo Chemical Co | Enzyme-amplified lateral flow device |
| CN112074739B (zh) * | 2018-05-02 | 2025-05-09 | 哈恩-席卡德应用研究学会 | 用于自动化系统的免疫测定 |
| WO2019221250A1 (ja) * | 2018-05-17 | 2019-11-21 | 株式会社テクノメデイカ | 競合イムノクロマト分析法及びイムノクロマトセンサ |
| CN109061176A (zh) * | 2018-06-29 | 2018-12-21 | 江南大学 | 一种检测血清总ⅰ型胶原氨基端延长肽的试剂盒及使用方法 |
| CN108872595A (zh) * | 2018-07-05 | 2018-11-23 | 潍坊市康华生物技术有限公司 | 一种癌胚抗原检测试剂盒及其制备方法 |
| CN112400113B (zh) | 2018-07-13 | 2022-04-15 | 3M创新有限公司 | 特异性结合化学发光测定法 |
| JP2021531458A (ja) | 2018-07-13 | 2021-11-18 | スリーエム イノベイティブ プロパティズ カンパニー | アッセイ |
| WO2020028619A1 (en) | 2018-08-01 | 2020-02-06 | Beckman Coulter, Inc. | Sparc based microorganism detection method |
| CN109142335A (zh) * | 2018-09-25 | 2019-01-04 | 无锡壹闪生物科技有限公司 | 空间邻近化学发光法检测降钙素原的试剂盒及其检测方法 |
| ES2942134T3 (es) * | 2018-09-25 | 2023-05-30 | Siemens Healthcare Diagnostics Inc | Composiciones, kits y métodos para ensayos multiplex para corregir la interferencia de biotina en mediciones de analitos diana |
| GB201909027D0 (en) * | 2019-06-24 | 2019-08-07 | Psyros Diagnostics Ltd | A method for detecting an analyte |
| CN119780445A (zh) * | 2024-12-31 | 2025-04-08 | 神州医疗生物科技(北京)有限公司 | 基于空间邻近化学发光的人磷酸化Tau-217蛋白检测方法及试剂盒 |
| CN119780444A (zh) * | 2024-12-31 | 2025-04-08 | 神州医疗生物科技(北京)有限公司 | 基于空间邻近化学发光的半乳糖凝集素3检测方法及试剂盒 |
| CN119780442A (zh) * | 2024-12-31 | 2025-04-08 | 神州医疗生物科技(北京)有限公司 | 基于空间邻近化学发光的超敏肌钙蛋白t检测方法及试剂盒 |
| CN119780443A (zh) * | 2024-12-31 | 2025-04-08 | 神州医疗生物科技(北京)有限公司 | 基于空间邻近化学发光的人磷酸化Tau-181蛋白检测方法、试剂盒及应用 |
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-
2007
- 2007-05-03 US US11/799,895 patent/US7732153B2/en active Active
- 2007-05-07 EP EP07761935.1A patent/EP2027453B1/en active Active
- 2007-05-07 WO PCT/US2007/068327 patent/WO2007133988A1/en not_active Ceased
- 2007-05-07 KR KR1020087027327A patent/KR20090042203A/ko not_active Ceased
- 2007-05-07 KR KR1020147036514A patent/KR20150006895A/ko not_active Ceased
- 2007-05-07 MX MX2011013319A patent/MX338982B/es unknown
- 2007-05-07 MX MX2008014293A patent/MX2008014293A/es active IP Right Grant
- 2007-05-07 AU AU2007249527A patent/AU2007249527B2/en not_active Ceased
- 2007-05-07 CN CN201010616899.1A patent/CN102175851B/zh active Active
- 2007-05-07 JP JP2009510116A patent/JP2009536745A/ja active Pending
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2008
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2010
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- 2011-09-02 US US13/224,702 patent/US8124362B2/en active Active
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