JP2009532189A - 可変量の薬剤を供給する吸入装置 - Google Patents

可変量の薬剤を供給する吸入装置 Download PDF

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Publication number
JP2009532189A
JP2009532189A JP2009504467A JP2009504467A JP2009532189A JP 2009532189 A JP2009532189 A JP 2009532189A JP 2009504467 A JP2009504467 A JP 2009504467A JP 2009504467 A JP2009504467 A JP 2009504467A JP 2009532189 A JP2009532189 A JP 2009532189A
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pack
drug
therapeutic agent
inhalation device
dose
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Japanese (ja)
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JP2009532189A5 (https=
Inventor
フレミング，スコット
グマステ，アナンド，ヴイ．
クリクスノフ，レオ，ビー．
アケルマン，アダン
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マイクロドース セラピューテクス，インコーポレイテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
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    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0003—Details of inhalators; Constructional features thereof with means for dispensing more than one drug
    • A—HUMAN NECESSITIES
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    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0005—Details of inhalators; Constructional features thereof with means for agitating the medicament
    • A61M15/001—Details of inhalators; Constructional features thereof with means for agitating the medicament using ultrasonic means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
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    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/0051—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged on a tape, e.g. strips
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    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B1/00—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means
    • B05B1/002—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means designed to reduce the generation or the transmission of noise or to produce a particular sound; associated with noise monitoring means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B12/00—Arrangements for controlling delivery; Arrangements for controlling the spray area
    • B05B12/08—Arrangements for controlling delivery; Arrangements for controlling the spray area responsive to condition of liquid or other fluent material to be discharged, of ambient medium or of target ; responsive to condition of spray devices or of supply means, e.g. pipes, pumps or their drive means
    • B05B12/081—Arrangements for controlling delivery; Arrangements for controlling the spray area responsive to condition of liquid or other fluent material to be discharged, of ambient medium or of target ; responsive to condition of spray devices or of supply means, e.g. pipes, pumps or their drive means responsive to the weight of a reservoir or container for liquid or other fluent material; responsive to level or volume of liquid or other fluent material in a reservoir or container
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B7/00—Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas
    • B05B7/14—Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas designed for spraying particulate materials
    • B05B7/1404—Arrangements for supplying particulate material
    • B05B7/144—Arrangements for supplying particulate material the means for supplying particulate material comprising moving mechanical means
    • B05B7/1445—Arrangements for supplying particulate material the means for supplying particulate material comprising moving mechanical means involving vibrations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/003—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter
    • A61M2016/0033—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical
    • A61M2016/0039—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical in the inspiratory circuit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
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    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3306—Optical measuring means
    • A—HUMAN NECESSITIES
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    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3375—Acoustical, e.g. ultrasonic, measuring means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/43—General characteristics of the apparatus making noise when used correctly
    • A—HUMAN NECESSITIES
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    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
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    • A61M2205/502—User interfaces, e.g. screens or keyboards
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    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/581—Means for facilitating use, e.g. by people with impaired vision by audible feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/583—Means for facilitating use, e.g. by people with impaired vision by visual feedback
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B7/00—Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas
    • B05B7/14—Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas designed for spraying particulate materials
    • B05B7/1404—Arrangements for supplying particulate material

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Anesthesiology (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mechanical Engineering (AREA)
  • Medicinal Preparation (AREA)
  • Eye Examination Apparatus (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Percussion Or Vibration Massage (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
JP2009504467A 2006-04-05 2007-04-04 可変量の薬剤を供給する吸入装置 Pending JP2009532189A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US78929006P 2006-04-05 2006-04-05
US11/696,683 US20070240712A1 (en) 2006-04-05 2007-04-04 Variable dose inhalation device
PCT/US2007/066005 WO2007121097A2 (en) 2006-04-05 2007-04-04 Variable dose inhalation device

Publications (2)

Publication Number Publication Date
JP2009532189A true JP2009532189A (ja) 2009-09-10
JP2009532189A5 JP2009532189A5 (https=) 2009-11-19

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US (1) US20070240712A1 (https=)
EP (1) EP2001537B1 (https=)
JP (1) JP2009532189A (https=)
KR (1) KR20090014155A (https=)
AT (1) ATE497800T1 (https=)
AU (1) AU2007238316A1 (https=)
BR (1) BRPI0710604A2 (https=)
CA (1) CA2648292A1 (https=)
CY (1) CY1111502T1 (https=)
DE (1) DE602007012420D1 (https=)
DK (1) DK2001537T3 (https=)
IL (1) IL194485A0 (https=)
MX (1) MX2008012784A (https=)
NZ (1) NZ572520A (https=)
PL (1) PL2001537T3 (https=)
PT (1) PT2001537E (https=)
RU (1) RU2427392C2 (https=)
SG (1) SG170835A1 (https=)
WO (1) WO2007121097A2 (https=)

Cited By (11)

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Publication number Priority date Publication date Assignee Title
JP2014513591A (ja) * 2011-03-15 2014-06-05 ノバルティス アーゲー 吸入器
JP2015037588A (ja) * 2010-01-05 2015-02-26 マイクロドース セラピューテクス，インコーポレイテッド 吸入デバイスおよび方法
JP2017523862A (ja) * 2014-08-13 2017-08-24 エルファー エルエルシー 吸入器の使用を促すシステム、方法、および装置
WO2018138788A1 (ja) * 2017-01-24 2018-08-02 大成化工株式会社 吸入判定装置および吸入器ユニット
JP2019529061A (ja) * 2016-10-11 2019-10-17 マイクロドース セラピューテクス，インコーポレイテッド 吸入器及びその使用方法
JP2020511243A (ja) * 2017-03-22 2020-04-16 マイクロドース セラピューテクス，インコーポレイテッド 光学的乾燥粉末吸入器用量センサ
JP2020520686A (ja) * 2017-05-26 2020-07-16 マイクロドース セラピューテクス，インコーポレイテッド 合成噴流を利用する吸入器
US10765817B2 (en) 2014-08-13 2020-09-08 Elwha, Llc Methods, systems, and devices related to delivery of alcohol with an inhaler
JP2022545519A (ja) * 2019-08-23 2022-10-27 イグンシェルト エセ．エレ． 吸入器における投与量測定デバイスおよび方法
JP2024517012A (ja) * 2021-05-17 2024-04-18 ヴェクトュラ・デリヴァリー・ディヴァイスィズ・リミテッド 乾燥粉末吸入器のためのアドヒアランスモニタ
JP2025523451A (ja) * 2022-08-23 2025-07-23 ケーティー アンド ジー コーポレイション 粉末吸入装置及びその制御方法

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WO2009067463A1 (en) 2007-11-19 2009-05-28 Proteus Biomedical, Inc. Body-associated fluid transport structure evaluation devices
EP2534957B1 (en) 2007-12-14 2015-05-27 AeroDesigns, Inc Delivering aerosolizable products
JP2009195669A (ja) * 2008-01-25 2009-09-03 Canon Inc 薬剤吐出装置及びその制御方法
KR101628410B1 (ko) * 2008-06-20 2016-06-08 맨카인드 코포레이션 흡입 활동에 관한 실시간 프로파일링을 위한 대화형 장치 및 방법
WO2010037058A2 (en) 2008-09-26 2010-04-01 Incube Labs, Llc Controlled inhaler for distributing inhalant according to inhalation velocity
JP5597646B2 (ja) * 2008-12-11 2014-10-01 コーニンクレッカ フィリップス エヌ ヴェ 薬剤の噴霧化を監視するシステム及び方法
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US20160367767A1 (en) * 2015-06-16 2016-12-22 Kathryn Cashman Inhalant device
WO2011073306A1 (en) * 2009-12-17 2011-06-23 Novartis Ag Inhaler device
EP2531099B1 (en) 2010-02-01 2018-12-12 Proteus Digital Health, Inc. Data gathering system
SG189763A1 (en) 2010-02-01 2013-05-31 Proteus Digital Health Inc Two-wrist data gathering system
MX339742B (es) * 2010-05-18 2016-06-07 Teva Pharma Ireland Contadores de dosis para inhaladores, inhaladores y flechas de los mismos.
FR2962925A1 (fr) 2010-07-20 2012-01-27 System Assistance Medical Nebuliseur et procede de fonctionnement d'un nebuliseur
US9308334B2 (en) 2010-09-30 2016-04-12 Novartis Ag Inhaler
CA2820554A1 (en) * 2010-11-29 2012-06-07 Sanofi-Aventis Deutschland Gmbh Medicated module for an inhaler
EP3834869B1 (en) 2010-12-22 2024-06-05 Syqe Medical Ltd. System for drug delivery
US10201673B2 (en) 2011-11-15 2019-02-12 Koninklijke Philips N.V. Nebulizer, a control unit for controlling the same and a method of operating a nebulizer
CA2856028C (en) * 2011-12-05 2020-01-07 Chiesi Farmaceutici S.P.A. Method and system for electronic mdi model
US11052202B2 (en) 2012-11-07 2021-07-06 Chiesi Farmaceutici S.P.A. Drug delivery device for the treatment of patients with respiratory diseases
CN105592935B (zh) 2013-07-24 2018-10-16 斯坦福设备有限公司 喷雾器振动孔板驱动频率控制及监测
US9427376B2 (en) * 2013-10-10 2016-08-30 Chiesi Farmaceutici S.P.A. Process for preparing pharmaceutical formulations for inhalation comprising a high-dosage strength active ingredient
PL3082484T3 (pl) * 2013-12-19 2020-05-18 Philip Morris Products S.A. Układ wytwarzania aerozolu
GB201401154D0 (en) * 2014-01-23 2014-03-12 Team Holdings Uk Ltd Medical apparatus and method
GB201410171D0 (en) 2014-06-09 2014-07-23 Nicoventures Holdings Ltd Electronic vapour provision system
US11298477B2 (en) 2014-06-30 2022-04-12 Syqe Medical Ltd. Methods, devices and systems for pulmonary delivery of active agents
CN113616883B (zh) 2014-06-30 2023-06-06 Syqe医药有限公司 向受试者肺部递送植物材料中的至少一药理活性剂的系统
RU2721064C2 (ru) 2014-06-30 2020-05-15 Сике Медикал Лтд. Ингалятор с регулированием потока
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RU2008143324A (ru) 2010-05-10
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