RU2427392C2 - Ингаляционное устройство с регулируемой дозой - Google Patents

Ингаляционное устройство с регулируемой дозой Download PDF

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Publication number
RU2427392C2
RU2427392C2 RU2008143324/14A RU2008143324A RU2427392C2 RU 2427392 C2 RU2427392 C2 RU 2427392C2 RU 2008143324/14 A RU2008143324/14 A RU 2008143324/14A RU 2008143324 A RU2008143324 A RU 2008143324A RU 2427392 C2 RU2427392 C2 RU 2427392C2
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Russia
Prior art keywords
drug
dose
packages
therapeutic agent
vibrator
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Application number
RU2008143324/14A
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English (en)
Russian (ru)
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RU2008143324A (ru
Inventor
Скотт ФЛЕМИНГ (US)
Скотт ФЛЕМИНГ
Ананд В. ГАМАСТ (US)
Ананд В. ГАМАСТ
Лео Б. КРИКСУНОВ (US)
Лео Б. КРИКСУНОВ
Адан ЭЙКЕРМАН (US)
Адан ЭЙКЕРМАН
Original Assignee
Майкродоуз Терапьютикс, Инк.
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0003Details of inhalators; Constructional features thereof with means for dispensing more than one drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0005Details of inhalators; Constructional features thereof with means for agitating the medicament
    • A61M15/001Details of inhalators; Constructional features thereof with means for agitating the medicament using ultrasonic means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
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    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033Details of the piercing or cutting means
    • A61M15/0035Piercing means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
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    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/005Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged on a cylindrical surface
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    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
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    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/0051Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged on a tape, e.g. strips
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • A61M15/0066Inhalators with dosage or measuring devices with means for varying the dose size
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • A61M15/0068Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/008Electronic counters
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B1/00Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means
    • B05B1/002Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means designed to reduce the generation or the transmission of noise or to produce a particular sound; associated with noise monitoring means
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B12/00Arrangements for controlling delivery; Arrangements for controlling the spray area
    • B05B12/08Arrangements for controlling delivery; Arrangements for controlling the spray area responsive to condition of liquid or other fluent material to be discharged, of ambient medium or of target ; responsive to condition of spray devices or of supply means, e.g. pipes, pumps or their drive means
    • B05B12/081Arrangements for controlling delivery; Arrangements for controlling the spray area responsive to condition of liquid or other fluent material to be discharged, of ambient medium or of target ; responsive to condition of spray devices or of supply means, e.g. pipes, pumps or their drive means responsive to the weight of a reservoir or container for liquid or other fluent material; responsive to level or volume of liquid or other fluent material in a reservoir or container
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B7/00Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas
    • B05B7/14Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas designed for spraying particulate materials
    • B05B7/1404Arrangements for supplying particulate material
    • B05B7/144Arrangements for supplying particulate material the means for supplying particulate material comprising moving mechanical means
    • B05B7/1445Arrangements for supplying particulate material the means for supplying particulate material comprising moving mechanical means involving vibrations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0003Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/003Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter
    • A61M2016/0033Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical
    • A61M2016/0039Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical in the inspiratory circuit
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/06Solids
    • A61M2202/064Powder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3306Optical measuring means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3375Acoustical, e.g. ultrasonic, measuring means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/43General characteristics of the apparatus making noise when used correctly
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/50General characteristics of the apparatus with microprocessors or computers
    • A61M2205/502User interfaces, e.g. screens or keyboards
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/58Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/581Means for facilitating use, e.g. by people with impaired vision by audible feedback
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/58Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/583Means for facilitating use, e.g. by people with impaired vision by visual feedback
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B7/00Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas
    • B05B7/14Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas designed for spraying particulate materials
    • B05B7/1404Arrangements for supplying particulate material

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Anesthesiology (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mechanical Engineering (AREA)
  • Medicinal Preparation (AREA)
  • Eye Examination Apparatus (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Percussion Or Vibration Massage (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
RU2008143324/14A 2006-04-05 2007-04-04 Ингаляционное устройство с регулируемой дозой RU2427392C2 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US78929006P 2006-04-05 2006-04-05
US60/789,290 2006-04-05
US11/696,683 2007-04-04
US11/696,683 US20070240712A1 (en) 2006-04-05 2007-04-04 Variable dose inhalation device

Publications (2)

Publication Number Publication Date
RU2008143324A RU2008143324A (ru) 2010-05-10
RU2427392C2 true RU2427392C2 (ru) 2011-08-27

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US (1) US20070240712A1 (https=)
EP (1) EP2001537B1 (https=)
JP (1) JP2009532189A (https=)
KR (1) KR20090014155A (https=)
AT (1) ATE497800T1 (https=)
AU (1) AU2007238316A1 (https=)
BR (1) BRPI0710604A2 (https=)
CA (1) CA2648292A1 (https=)
CY (1) CY1111502T1 (https=)
DE (1) DE602007012420D1 (https=)
DK (1) DK2001537T3 (https=)
IL (1) IL194485A0 (https=)
MX (1) MX2008012784A (https=)
NZ (1) NZ572520A (https=)
PL (1) PL2001537T3 (https=)
PT (1) PT2001537E (https=)
RU (1) RU2427392C2 (https=)
SG (1) SG170835A1 (https=)
WO (1) WO2007121097A2 (https=)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2633269C2 (ru) * 2011-12-05 2017-10-11 КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. Способ и система для электронной модели mdi (дозирующего ингалятора)
RU2728689C2 (ru) * 2014-06-30 2020-07-30 Сике Медикал Лтд. Способы, устройства и системы для легочной доставки активных средств
US10857313B2 (en) 2014-07-01 2020-12-08 Aerami Therapeutics, Inc. Liquid nebulization systems and methods
RU2827979C1 (ru) * 2019-12-23 2024-10-04 Филип Моррис Продактс С.А. Генератор аэрозоля, содержащий питающие элементы

Families Citing this family (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008008281A2 (en) 2006-07-07 2008-01-17 Proteus Biomedical, Inc. Smart parenteral administration system
US8528544B2 (en) * 2007-05-30 2013-09-10 Canon Kabushiki Kaisha Inhaler
AU2008317307A1 (en) * 2007-10-25 2009-04-30 Novartis Ag Powder conditioning of unit dose drug packages
WO2009055733A1 (en) 2007-10-25 2009-04-30 Proteus Biomedical, Inc. Fluid transfer port information system
WO2009067463A1 (en) 2007-11-19 2009-05-28 Proteus Biomedical, Inc. Body-associated fluid transport structure evaluation devices
EP2534957B1 (en) 2007-12-14 2015-05-27 AeroDesigns, Inc Delivering aerosolizable products
JP2009195669A (ja) * 2008-01-25 2009-09-03 Canon Inc 薬剤吐出装置及びその制御方法
KR101628410B1 (ko) * 2008-06-20 2016-06-08 맨카인드 코포레이션 흡입 활동에 관한 실시간 프로파일링을 위한 대화형 장치 및 방법
WO2010037058A2 (en) 2008-09-26 2010-04-01 Incube Labs, Llc Controlled inhaler for distributing inhalant according to inhalation velocity
JP5597646B2 (ja) * 2008-12-11 2014-10-01 コーニンクレッカ フィリップス エヌ ヴェ 薬剤の噴霧化を監視するシステム及び方法
AU2010249402B2 (en) * 2009-05-21 2014-08-21 Microdose Therapeutx, Inc. Rotary cassette system for dry powder inhaler
US20160367767A1 (en) * 2015-06-16 2016-12-22 Kathryn Cashman Inhalant device
WO2011073306A1 (en) * 2009-12-17 2011-06-23 Novartis Ag Inhaler device
CN105381524A (zh) * 2010-01-05 2016-03-09 微剂量治疗技术公司 吸入设备和方法
EP2531099B1 (en) 2010-02-01 2018-12-12 Proteus Digital Health, Inc. Data gathering system
SG189763A1 (en) 2010-02-01 2013-05-31 Proteus Digital Health Inc Two-wrist data gathering system
MX339742B (es) * 2010-05-18 2016-06-07 Teva Pharma Ireland Contadores de dosis para inhaladores, inhaladores y flechas de los mismos.
FR2962925A1 (fr) 2010-07-20 2012-01-27 System Assistance Medical Nebuliseur et procede de fonctionnement d'un nebuliseur
US9308334B2 (en) 2010-09-30 2016-04-12 Novartis Ag Inhaler
CA2820554A1 (en) * 2010-11-29 2012-06-07 Sanofi-Aventis Deutschland Gmbh Medicated module for an inhaler
EP3834869B1 (en) 2010-12-22 2024-06-05 Syqe Medical Ltd. System for drug delivery
EP2686049B1 (en) * 2011-03-15 2015-03-04 Novartis AG Inhaler
US10201673B2 (en) 2011-11-15 2019-02-12 Koninklijke Philips N.V. Nebulizer, a control unit for controlling the same and a method of operating a nebulizer
US11052202B2 (en) 2012-11-07 2021-07-06 Chiesi Farmaceutici S.P.A. Drug delivery device for the treatment of patients with respiratory diseases
CN105592935B (zh) 2013-07-24 2018-10-16 斯坦福设备有限公司 喷雾器振动孔板驱动频率控制及监测
US9427376B2 (en) * 2013-10-10 2016-08-30 Chiesi Farmaceutici S.P.A. Process for preparing pharmaceutical formulations for inhalation comprising a high-dosage strength active ingredient
PL3082484T3 (pl) * 2013-12-19 2020-05-18 Philip Morris Products S.A. Układ wytwarzania aerozolu
GB201401154D0 (en) * 2014-01-23 2014-03-12 Team Holdings Uk Ltd Medical apparatus and method
GB201410171D0 (en) 2014-06-09 2014-07-23 Nicoventures Holdings Ltd Electronic vapour provision system
US11298477B2 (en) 2014-06-30 2022-04-12 Syqe Medical Ltd. Methods, devices and systems for pulmonary delivery of active agents
CN113616883B (zh) 2014-06-30 2023-06-06 Syqe医药有限公司 向受试者肺部递送植物材料中的至少一药理活性剂的系统
RU2721064C2 (ru) 2014-06-30 2020-05-15 Сике Медикал Лтд. Ингалятор с регулированием потока
IL273507B2 (en) 2014-06-30 2024-06-01 Syqe Medical Ltd Methods, devices and systems for administering active substances through the lungs
AU2015283589B2 (en) 2014-06-30 2019-09-12 Syqe Medical Ltd. Method and device for vaporization and inhalation of isolated substances
RU2723335C2 (ru) 2014-06-30 2020-06-09 Сике Медикал Лтд. Дозовый картридж для ингалятора
US11273271B2 (en) * 2014-07-01 2022-03-15 Aerami Therapeutics, Inc. Aerosolization system with flow restrictor and feedback device
US10987048B2 (en) 2014-08-13 2021-04-27 Elwha Llc Systems, methods, and devices to incentivize inhaler use
US10765817B2 (en) 2014-08-13 2020-09-08 Elwha, Llc Methods, systems, and devices related to delivery of alcohol with an inhaler
US10245393B2 (en) 2014-08-13 2019-04-02 Elwha Llc Methods, systems, and devices related to a supplemental inhaler
MX2017013260A (es) * 2015-04-15 2019-03-28 Philip Morris Products Sa Inhalador de polvo seco de resistencia dual.
CA3009599A1 (en) 2016-01-06 2017-07-13 Syqe Medical Ltd. Low dose therapeutic treatment
WO2017201463A1 (en) 2016-05-19 2017-11-23 Mannkind Corporation Apparatus, system and method for detecting and monitoring inhalations
IT201600093878A1 (it) * 2016-09-19 2018-03-19 Hollycon Italy Pte Ltd S R L Inalatore monodose a perdere per medicinali in polvere
AU2017342012A1 (en) * 2016-10-11 2019-05-16 Microdose Therapeutx, Inc. Inhaler and methods of use thereof
WO2018071423A1 (en) * 2016-10-11 2018-04-19 Microdose Therapeutx, Inc. Inhaler and methods of use thereof
EA038716B1 (ru) * 2016-10-11 2021-10-08 Майкродоуз Терапьютикс, Инк. Ингалятор и способ его использования
US10238821B2 (en) 2016-10-11 2019-03-26 Microdose Therapeutx, Inc. Inhaler and methods of use thereof
US10677761B2 (en) 2016-12-01 2020-06-09 Avery Dennison Retail Information Services, Llc Systems and methods for monitoring blister pack compliance
KR20190092517A (ko) 2016-12-09 2019-08-07 마이크로도스 테라퓨특스, 인코포레이티드 흡입기
WO2018138788A1 (ja) * 2017-01-24 2018-08-02 大成化工株式会社 吸入判定装置および吸入器ユニット
CA3056897A1 (en) * 2017-03-22 2018-09-27 Microdose Therapeutx, Inc. Optical dry powder inhaler dose sensor
CA3059239A1 (en) * 2017-05-26 2018-11-29 Microdose Therapeutx, Inc. Inhaler with synthetic jetting
MX2019014016A (es) 2017-05-31 2020-02-17 Philip Morris Products Sa Articulo inhalador con elemento de flujo de aire ocluido.
AU2019221321B2 (en) * 2018-02-15 2025-01-23 Syqe Medical Ltd. Method and inhaler for providing two or more substances by inhalation
TR201803793A2 (tr) * 2018-03-16 2018-06-21 Inofab Saglik Teknolojileri Anonim Sirketi İnhalatör eklenti̇si̇
KR102032432B1 (ko) * 2018-06-08 2019-10-15 황기형 호흡기 온훈증 약탕기
US11090449B2 (en) * 2018-08-21 2021-08-17 Vivera Pharmaceuticals Inc. Smart inhaler device with automated dose delivery, measurement, and management
US11450420B2 (en) 2018-08-21 2022-09-20 Vivera Pharmaceuticals Inc. Secure smart dosing system with automated delivery, measurement, and management for pills
US11083850B2 (en) * 2018-08-21 2021-08-10 Vivera Pharmaceuticals Inc. Secure smart dosing system with automated delivery, measurement, and management
EP3693044A1 (en) 2019-02-07 2020-08-12 Koninklijke Philips N.V. Breath actuated inhalers
FR3096040B1 (fr) 2019-05-17 2021-09-24 Aptar France Sas Dispositif de distribution de produit fluide
ES2807698B2 (es) * 2019-08-23 2022-01-03 Igncyerto S L Dispositivo y metodo de medicion de dosis en inhaladores de polvo seco
US12427270B2 (en) 2019-11-18 2025-09-30 Vectura Delivery Devices Limited Inhaler for use with a compliance monitor
US20220395652A1 (en) * 2019-11-18 2022-12-15 Vectura Delivery Devices Limited Dry powder inhaler with an adherence/compliance monitor
KR102755135B1 (ko) * 2019-11-18 2025-01-14 벡투라 딜리버리 디바이시스 리미티드 엄수 모니터를 갖는 건조 분말 흡입기
US20240024594A1 (en) * 2020-08-10 2024-01-25 Hatchmore Labs GmbH Nasal applicator
MX2023013704A (es) * 2021-05-17 2024-01-16 Vectura Delivery Devices Ltd Monitor de adherencia para un inhalador de polvo seco.
US20250058059A1 (en) * 2021-12-17 2025-02-20 Stamford Devices Limited A nebulizer with plume detection
EP4197646A1 (en) * 2021-12-17 2023-06-21 Stamford Devices Limited A nebulizer with plume detection
KR20240027929A (ko) * 2022-08-23 2024-03-05 주식회사 케이티앤지 분말 흡입 장치 및 그 제어 방법

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1597195A1 (ru) * 1988-11-04 1990-10-07 Egin Nikolaj L Ингал тор
US5672581A (en) * 1993-01-29 1997-09-30 Aradigm Corporation Method of administration of insulin
RU2136322C1 (ru) * 1994-04-14 1999-09-10 Дьюра Фармасьютикалз, Инк. Ингалятор для сухого порошка
US6543443B1 (en) * 2000-07-12 2003-04-08 Aerogen, Inc. Methods and devices for nebulizing fluids
RU2207886C2 (ru) * 1997-12-12 2003-07-10 Астразенека Аб Устройство для ингаляции и способ ингаляции

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2517482A (en) * 1949-04-09 1950-08-01 Sharp & Dohme Inc Inhaler
US3507277A (en) * 1966-09-17 1970-04-21 Fisons Pharmaceuticals Ltd Inhalation device
GB1182779A (en) * 1966-09-17 1970-03-04 Fisons Pharmaceuticals Ltd Inhalation Device
GB1268051A (en) * 1968-06-07 1972-03-22 Fisons Pharmaceuticals Ltd Inhalation device
US3831606A (en) * 1971-02-19 1974-08-27 Alza Corp Auto inhaler
IT941426B (it) * 1971-07-17 1973-03-01 Isf Spa Inalatore a camera di turbinio per sostanze medicamentose polveriformi
US3795244A (en) * 1973-02-02 1974-03-05 Syntex Corp Inhalation device
US3948264A (en) * 1975-05-21 1976-04-06 Mead Johnson & Company Inhalation device
CA2058764A1 (en) * 1989-04-28 1990-10-29 Peter D. Hodson Dry powder inhalation device
DE69230613T2 (de) * 1991-07-02 2000-12-28 Inhale Inc Verfahren und vorrichtung zum abgeben von medikamenten in aerosolform
US5284133A (en) * 1992-07-23 1994-02-08 Armstrong Pharmaceuticals, Inc. Inhalation device with a dose-timer, an actuator mechanism, and patient compliance monitoring means
US5694920A (en) 1996-01-25 1997-12-09 Abrams; Andrew L. Inhalation device
US6142146A (en) 1998-06-12 2000-11-07 Microdose Technologies, Inc. Inhalation device
DE69928928T2 (de) * 1998-06-12 2006-08-03 Microdose Technologies Inc. Vorrichtung zur abgabe von arzneimitteln
US6152130A (en) * 1998-06-12 2000-11-28 Microdose Technologies, Inc. Inhalation device with acoustic control
GB2345010B (en) * 1998-12-17 2002-12-31 Electrosols Ltd A delivery device
US7080644B2 (en) * 2000-06-28 2006-07-25 Microdose Technologies, Inc. Packaging and delivery of pharmaceuticals and drugs
US6550472B2 (en) 2001-03-16 2003-04-22 Aerogen, Inc. Devices and methods for nebulizing fluids using flow directors
US20020138588A1 (en) * 2001-03-20 2002-09-26 Richard Leeds System and method for adaptive forums communication
US7305436B2 (en) * 2002-05-17 2007-12-04 Sap Aktiengesellschaft User collaboration through discussion forums
GB0217196D0 (en) * 2002-07-25 2002-09-04 Glaxo Group Ltd Medicament dispenser
US20070221218A1 (en) * 2003-10-27 2007-09-27 Warden Jeffrey A Dry Powder Drug Containment System Packages with Tabs, Inhalers and Associated Methods
EP1723489A4 (en) * 2004-02-06 2011-03-23 Microdose Therapeutx Inc BLISTER PACK FOR USE WITH AN INHALATION DEVICE
WO2005081833A2 (en) 2004-02-24 2005-09-09 Microdose Technologies, Inc. Synthetic jet based medicament delivery method and apparatus
MXPA06009516A (es) * 2004-02-24 2007-03-26 Microdose Technologies Inc Inhalador con sensor de flujo direccional.

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1597195A1 (ru) * 1988-11-04 1990-10-07 Egin Nikolaj L Ингал тор
US5672581A (en) * 1993-01-29 1997-09-30 Aradigm Corporation Method of administration of insulin
RU2136322C1 (ru) * 1994-04-14 1999-09-10 Дьюра Фармасьютикалз, Инк. Ингалятор для сухого порошка
RU2207886C2 (ru) * 1997-12-12 2003-07-10 Астразенека Аб Устройство для ингаляции и способ ингаляции
US6543443B1 (en) * 2000-07-12 2003-04-08 Aerogen, Inc. Methods and devices for nebulizing fluids

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2633269C2 (ru) * 2011-12-05 2017-10-11 КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. Способ и система для электронной модели mdi (дозирующего ингалятора)
RU2728689C2 (ru) * 2014-06-30 2020-07-30 Сике Медикал Лтд. Способы, устройства и системы для легочной доставки активных средств
US10857313B2 (en) 2014-07-01 2020-12-08 Aerami Therapeutics, Inc. Liquid nebulization systems and methods
RU2827979C1 (ru) * 2019-12-23 2024-10-04 Филип Моррис Продактс С.А. Генератор аэрозоля, содержащий питающие элементы
US12616242B2 (en) 2019-12-23 2026-05-05 Philip Morris Products S.A. Aerosol-generator comprising multiple supply elements

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CA2648292A1 (en) 2007-10-25
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CY1111502T1 (el) 2015-08-05
WO2007121097A3 (en) 2008-11-06
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EP2001537B1 (en) 2011-02-09
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RU2008143324A (ru) 2010-05-10
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