JP2009530423A - アミロイド生成性疾患を予防および処置するための方法 - Google Patents

アミロイド生成性疾患を予防および処置するための方法 Download PDF

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JP2009530423A
JP2009530423A JP2009501727A JP2009501727A JP2009530423A JP 2009530423 A JP2009530423 A JP 2009530423A JP 2009501727 A JP2009501727 A JP 2009501727A JP 2009501727 A JP2009501727 A JP 2009501727A JP 2009530423 A JP2009530423 A JP 2009530423A
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antibody
rage
human
binding
variable region
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ジャック スティーブン ジェイコブセン，
シャン−ヤン タン，
リウドミラ チスティアコバ，
スレクマー ラマン コダンガッティル，
アンジェラ ウィドム，
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Wyeth LLC
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • C07K2317/00—Immunoglobulins specific features
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
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    • C07—ORGANIC CHEMISTRY
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
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    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

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JP2009501727A 2006-03-21 2007-03-21 アミロイド生成性疾患を予防および処置するための方法 Withdrawn JP2009530423A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US78457506P 2006-03-21 2006-03-21
US89530307P 2007-03-16 2007-03-16
PCT/US2007/064571 WO2007109749A2 (en) 2006-03-21 2007-03-21 Methods for preventing and treating amyloidogenic diseases

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JP2009530423A true JP2009530423A (ja) 2009-08-27
JP2009530423A5 JP2009530423A5 (https=) 2011-05-26

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JP2009501727A Withdrawn JP2009530423A (ja) 2006-03-21 2007-03-21 アミロイド生成性疾患を予防および処置するための方法
JP2009501725A Pending JP2009529920A (ja) 2006-03-21 2007-03-21 Ｒａｇｅの拮抗作用のための方法および組成物

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US (2) US20070253950A1 (https=)
EP (2) EP2004694A2 (https=)
JP (2) JP2009530423A (https=)
KR (2) KR20080110833A (https=)
AU (2) AU2007226861A1 (https=)
BR (2) BRPI0708998A2 (https=)
CA (2) CA2638755A1 (https=)
CR (2) CR10298A (https=)
EC (1) ECSP088750A (https=)
MX (2) MX2008012023A (https=)
NO (2) NO20083720L (https=)
RU (2) RU2008134135A (https=)
WO (2) WO2007109747A2 (https=)

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