|
US20100168034A1
(en)
|
2006-02-20 |
2010-07-01 |
Ewha University-Industry Collaboration Foundation |
Peptide having cell membrane penetrating activity
|
|
KR101169030B1
(ko)
*
|
2009-01-21 |
2012-07-26 |
애니젠 주식회사 |
신규한 세포막 투과 도메인 및 이를 포함하는 세포내 전달 시스템
|
|
CA2807552A1
(en)
|
2010-08-06 |
2012-02-09 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
|
EP3431485B2
(en)
|
2010-10-01 |
2024-09-04 |
ModernaTX, Inc. |
Engineered nucleic acids and methods of use thereof
|
|
WO2012135805A2
(en)
|
2011-03-31 |
2012-10-04 |
modeRNA Therapeutics |
Delivery and formulation of engineered nucleic acids
|
|
US9464124B2
(en)
|
2011-09-12 |
2016-10-11 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
|
EP2763701B1
(en)
|
2011-10-03 |
2018-12-19 |
Moderna Therapeutics, Inc. |
Modified nucleosides, nucleotides, and nucleic acids, and uses thereof
|
|
KR20140102759A
(ko)
|
2011-12-16 |
2014-08-22 |
모더나 세라퓨틱스, 인코포레이티드 |
변형된 뉴클레오사이드, 뉴클레오타이드 및 핵산 조성물
|
|
DE18200782T1
(de)
|
2012-04-02 |
2021-10-21 |
Modernatx, Inc. |
Modifizierte polynukleotide zur herstellung von proteinen im zusammenhang mit erkrankungen beim menschen
|
|
US9283287B2
(en)
|
2012-04-02 |
2016-03-15 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of nuclear proteins
|
|
US9878056B2
(en)
|
2012-04-02 |
2018-01-30 |
Modernatx, Inc. |
Modified polynucleotides for the production of cosmetic proteins and peptides
|
|
US9572897B2
(en)
|
2012-04-02 |
2017-02-21 |
Modernatx, Inc. |
Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
|
|
CN108841802B
(zh)
|
2012-05-11 |
2023-06-09 |
珍白斯凯尔有限公司 |
抗炎性肽及包含其的组合物
|
|
KR101873773B1
(ko)
|
2012-05-11 |
2018-08-02 |
주식회사 젬백스앤카엘 |
류마티즘 관절염 예방 또는 치료 조성물
|
|
JP6272853B2
(ja)
*
|
2012-07-11 |
2018-01-31 |
ジェムバックス アンド カエル カンパニー，リミティド |
細胞透過性ペプチド、それを含んだコンジュゲート、及びそれを含んだ組成物
|
|
CN110028554B
(zh)
|
2012-09-19 |
2023-04-07 |
珍白斯凯尔有限公司 |
细胞穿透性肽、包含该肽的缀合物、及包含该缀合物的组合物
|
|
JP6517692B2
(ja)
|
2012-09-19 |
2019-05-22 |
ジェムバックス アンド カエル カンパニー，リミティド |
細胞透過性ペプチド、それを含んだコンジュゲート、及びそれを含んだ組成物
|
|
CA2892529C
(en)
|
2012-11-26 |
2023-04-25 |
Moderna Therapeutics, Inc. |
Terminally modified rna
|
|
KR101495417B1
(ko)
*
|
2013-01-31 |
2015-02-26 |
이화여자대학교 산학협력단 |
인슐린 점막 투과 개선용 조성물
|
|
WO2014152211A1
(en)
|
2013-03-14 |
2014-09-25 |
Moderna Therapeutics, Inc. |
Formulation and delivery of modified nucleoside, nucleotide, and nucleic acid compositions
|
|
US8980864B2
(en)
|
2013-03-15 |
2015-03-17 |
Moderna Therapeutics, Inc. |
Compositions and methods of altering cholesterol levels
|
|
KR101595152B1
(ko)
*
|
2013-04-10 |
2016-02-17 |
이화여자대학교 산학협력단 |
Ｔｃｔｐ-ｐｔｄ를 포함하는 유전자 전달체
|
|
WO2014171792A1
(ko)
|
2013-04-19 |
2014-10-23 |
주식회사 카엘젬백스 |
허혈성 손상 치료 및 예방용 조성물
|
|
KR101491016B1
(ko)
*
|
2013-05-31 |
2015-02-10 |
건국대학교 산학협력단 |
배반포 및 생식기관 암 세포 특이적인 단백질 운반 방법 및 그 조성물
|
|
EP4063863A1
(en)
|
2013-06-07 |
2022-09-28 |
Gemvax & Kael Co., Ltd. |
Gv1001, gemcitabine and capecitabine for use in the treatment of pancreatic cancer in high eotaxin baseline level patients
|
|
CN105324123B
(zh)
|
2013-06-21 |
2022-02-08 |
珍白斯凯尔有限公司 |
激素分泌调节剂、包含该调节剂的组合物、和利用其控制激素分泌的方法
|
|
US20160194368A1
(en)
|
2013-09-03 |
2016-07-07 |
Moderna Therapeutics, Inc. |
Circular polynucleotides
|
|
EP3041934A1
(en)
|
2013-09-03 |
2016-07-13 |
Moderna Therapeutics, Inc. |
Chimeric polynucleotides
|
|
US10023626B2
(en)
|
2013-09-30 |
2018-07-17 |
Modernatx, Inc. |
Polynucleotides encoding immune modulating polypeptides
|
|
EA201690675A1
(ru)
|
2013-10-03 |
2016-08-31 |
Модерна Терапьютикс, Инк. |
Полинуклеотиды, кодирующие рецептор липопротеинов низкой плотности
|
|
CN110755599A
(zh)
|
2013-10-23 |
2020-02-07 |
珍白斯凯尔有限公司 |
用于治疗和预防良性前列腺增生的组合物
|
|
GB201318954D0
(en)
*
|
2013-10-28 |
2013-12-11 |
Cupid Peptide Company Ltd |
Cell transport
|
|
EP3072519B1
(en)
|
2013-11-22 |
2020-08-19 |
Gemvax & Kael Co., Ltd. |
Peptide having angiogenesis inhibitory activity and composition containing same
|
|
EP3080273A4
(en)
|
2013-12-13 |
2017-11-08 |
Basf Se |
Recombinant microorganism for improved production of fine chemicals
|
|
US11058744B2
(en)
|
2013-12-17 |
2021-07-13 |
Gemvax & Kael Co., Ltd. |
Composition for treating prostate cancer
|
|
ES2908096T3
(es)
|
2014-04-11 |
2022-04-27 |
Gemvax & Kael Co Ltd |
Péptido con actividad inhibidora de la fibrosis y composición que lo contiene
|
|
WO2015167067A1
(ko)
|
2014-04-30 |
2015-11-05 |
주식회사 카엘젬백스 |
장기, 조직 또는 세포 이식용 조성물, 키트 및 이식 방법
|
|
PL3149025T3
(pl)
*
|
2014-05-21 |
2019-11-29 |
Entrada Therapeutics Inc |
Peptydy penetrujące komórkę i sposoby ich wytwarzania i stosowania
|
|
EP3156063B1
(en)
|
2014-06-16 |
2019-12-25 |
Ewha University-Industry Collaboration Foundation |
Binding inhibitor between tctp dimer type ige-dependent histamine releasing factor and receptor thereof, and use thereof
|
|
US20170210788A1
(en)
|
2014-07-23 |
2017-07-27 |
Modernatx, Inc. |
Modified polynucleotides for the production of intrabodies
|
|
KR102413243B1
(ko)
|
2014-12-23 |
2022-06-27 |
주식회사 젬백스앤카엘 |
안질환 치료 펩티드 및 이를 포함하는 안질환 치료용 조성물
|
|
CN107405380B
(zh)
|
2015-02-27 |
2021-04-20 |
珍白斯凯尔有限公司 |
用于预防听觉损伤的肽及其包含该肽的组合物
|
|
KR20180004752A
(ko)
|
2015-05-26 |
2018-01-12 |
주식회사 젬백스앤카엘 |
신규 펩티드 및 이를 포함한 조성물
|
|
JP6923453B2
(ja)
|
2015-07-02 |
2021-08-18 |
ジェムバックス アンド カエル カンパニー，リミティド |
抗ウイルス活性効能を有するペプチド及びこれを含む組成物
|
|
CN108350030B
(zh)
*
|
2015-09-10 |
2022-12-13 |
汉阳大学校产学协力团 |
皮肤可渗透肽及其使用方法
|
|
WO2017079725A1
(en)
|
2015-11-06 |
2017-05-11 |
The Board Of Trustees Of The University Of Illinois |
Peptides and method for treatment of cardiac arrest
|
|
CN116082457A
(zh)
|
2016-02-01 |
2023-05-09 |
堪培拉大学 |
蛋白化合物及其用途
|
|
WO2017176076A1
(en)
|
2016-04-06 |
2017-10-12 |
Ewha University - Industry Collaboration Foundation |
A peptide with ability to penetrate cell membrane
|
|
JP6795679B2
(ja)
*
|
2016-04-06 |
2020-12-02 |
アイキュア ビーエヌピー カンパニー リミテッド |
細胞膜に浸透する能力を有するペプチド
|
|
WO2017176087A1
(ko)
|
2016-04-07 |
2017-10-12 |
주식회사 젬백스앤카엘 |
텔로머라제 활성 증가 및 텔로미어 연장 효능을 가지는 펩티드 및 이를 포함하는 조성물
|
|
MA50213A
(fr)
*
|
2016-12-16 |
2020-07-22 |
Avixgen Inc |
Peptide de transduction cytoplasmique et messager intracellulaire le comprenant
|
|
WO2018213731A1
(en)
|
2017-05-18 |
2018-11-22 |
Modernatx, Inc. |
Polynucleotides encoding tethered interleukin-12 (il12) polypeptides and uses thereof
|
|
EP3625345B1
(en)
|
2017-05-18 |
2023-05-24 |
ModernaTX, Inc. |
Modified messenger rna comprising functional rna elements
|
|
EP3638292A1
(en)
|
2017-06-14 |
2020-04-22 |
ModernaTX, Inc. |
Polynucleotides encoding coagulation factor viii
|
|
US10781435B2
(en)
|
2017-06-22 |
2020-09-22 |
Catalyst Biosciences, Inc. |
Modified membrane type serine protease 1 (MTSP-1) polypeptides and methods of use
|
|
SG11202004167XA
(en)
|
2017-11-08 |
2020-06-29 |
Epiaxis Therapeutics Pty Ltd |
Immunogenic compositions and uses therefor
|
|
EP3714045A1
(en)
|
2017-11-22 |
2020-09-30 |
Modernatx, Inc. |
Polynucleotides encoding propionyl-coa carboxylase alpha and beta subunits for the treatment of propionic acidemia
|
|
US11939601B2
(en)
|
2017-11-22 |
2024-03-26 |
Modernatx, Inc. |
Polynucleotides encoding phenylalanine hydroxylase for the treatment of phenylketonuria
|
|
WO2019104152A1
(en)
|
2017-11-22 |
2019-05-31 |
Modernatx, Inc. |
Polynucleotides encoding ornithine transcarbamylase for the treatment of urea cycle disorders
|
|
KR101933217B1
(ko)
|
2017-12-28 |
2018-12-27 |
(주) 에빅스젠 |
피부 염증 억제용 펩티드 및 이를 포함하는 피부 염증 예방 또는 치료용 조성물
|
|
US11802146B2
(en)
|
2018-01-05 |
2023-10-31 |
Modernatx, Inc. |
Polynucleotides encoding anti-chikungunya virus antibodies
|
|
EP3790890A4
(en)
|
2018-05-09 |
2022-03-02 |
Ohio State Innovation Foundation |
CYCLIC PEPTIDES OF CELL PENETRATION WITH ONE OR MORE HYDROPHOBIC RESIDUES
|
|
EP3796893A1
(en)
|
2018-05-23 |
2021-03-31 |
Modernatx, Inc. |
Delivery of dna
|
|
US20220184185A1
(en)
|
2018-07-25 |
2022-06-16 |
Modernatx, Inc. |
Mrna based enzyme replacement therapy combined with a pharmacological chaperone for the treatment of lysosomal storage disorders
|
|
US10842827B2
(en)
*
|
2018-08-22 |
2020-11-24 |
José Manuel Aguilar Yáñez |
Treatment and compound for epithelial wounds
|
|
US20220110966A1
(en)
|
2018-09-02 |
2022-04-14 |
Modernatx, Inc. |
Polynucleotides encoding very long-chain acyl-coa dehydrogenase for the treatment of very long-chain acyl-coa dehydrogenase deficiency
|
|
WO2020056147A2
(en)
|
2018-09-13 |
2020-03-19 |
Modernatx, Inc. |
Polynucleotides encoding glucose-6-phosphatase for the treatment of glycogen storage disease
|
|
MA53608A
(fr)
|
2018-09-13 |
2021-07-21 |
Modernatx Inc |
Polynucléotides codant pour les sous-unités e1-alpha, e1-beta et e2 du complexe alpha-cétoacide déshydrogénase à chaîne ramifiée pour le traitement de la leucinose
|
|
CA3112398A1
(en)
|
2018-09-14 |
2020-03-19 |
Modernatx, Inc. |
Polynucleotides encoding uridine diphosphate glycosyltransferase 1 family, polypeptide a1 for the treatment of crigler-najjar syndrome
|
|
US20220152225A1
(en)
|
2018-09-27 |
2022-05-19 |
Modernatx, Inc. |
Polynucleotides encoding arginase 1 for the treatment of arginase deficiency
|
|
US11613744B2
(en)
|
2018-12-28 |
2023-03-28 |
Vertex Pharmaceuticals Incorporated |
Modified urokinase-type plasminogen activator polypeptides and methods of use
|
|
PE20211664A1
(es)
|
2018-12-28 |
2021-08-26 |
Catalyst Biosciences Inc |
Polipeptidos de activador de plasminogeno, tipo urocinasa, modificados y metodos de uso
|
|
KR20210134716A
(ko)
|
2019-03-01 |
2021-11-10 |
플래그쉽 파이어니어링 이노베이션스 브이아이, 엘엘씨 |
폴리리보뉴클레오티드의 전달을 위한 조성물, 방법, 및 키트
|
|
AU2020232238B2
(en)
|
2019-03-01 |
2025-10-30 |
Flagship Pioneering Innovations Vi, Llc |
Polyribonucleotides and cosmetic uses thereof
|
|
EP3965797A1
(en)
|
2019-05-08 |
2022-03-16 |
AstraZeneca AB |
Compositions for skin and wounds and methods of use thereof
|
|
CN112694522B
(zh)
*
|
2020-03-11 |
2022-06-14 |
浙江大学 |
一种基于GluN2A亚基的细胞穿膜肽及其应用
|
|
KR102274999B1
(ko)
*
|
2020-04-23 |
2021-07-08 |
주식회사 아임뉴런바이오사이언스 |
신규한 세포 투과성 펩타이드 및 이의 용도
|
|
AU2021275213A1
(en)
|
2020-05-20 |
2023-02-02 |
Flagship Pioneering Innovations Vi, Llc |
Immunogenic compositions and uses thereof
|
|
US20230235298A1
(en)
|
2020-06-01 |
2023-07-27 |
Modernatx, Inc. |
Phenylalanine hydroxylase variants and uses thereof
|
|
WO2022051629A1
(en)
|
2020-09-03 |
2022-03-10 |
Flagship Pioneering Innovations Vi, Llc |
Immunogenic compositions and uses thereof
|
|
AU2021377895A1
(en)
|
2020-11-13 |
2023-06-15 |
Modernatx, Inc. |
Polynucleotides encoding cystic fibrosis transmembrane conductance regulator for the treatment of cystic fibrosis
|
|
KR20220085522A
(ko)
*
|
2020-12-15 |
2022-06-22 |
주식회사 아이큐어비앤피 |
세포막 투과성을 갖는 신규 펩타이드
|
|
WO2022204380A1
(en)
|
2021-03-24 |
2022-09-29 |
Modernatx, Inc. |
Lipid nanoparticles containing polynucleotides encoding propionyl-coa carboxylase alpha and beta subunits and uses thereof
|
|
JP2024512026A
(ja)
|
2021-03-24 |
2024-03-18 |
モデルナティエックス インコーポレイテッド |
オルニチントランスカルバミラーゼ欠損症の治療を目的とした脂質ナノ粒子及びオルニチントランスカルバミラーゼをコードするポリヌクレオチド
|
|
WO2022204369A1
(en)
|
2021-03-24 |
2022-09-29 |
Modernatx, Inc. |
Polynucleotides encoding methylmalonyl-coa mutase for the treatment of methylmalonic acidemia
|
|
WO2022204390A1
(en)
|
2021-03-24 |
2022-09-29 |
Modernatx, Inc. |
Lipid nanoparticles containing polynucleotides encoding phenylalanine hydroxylase and uses thereof
|
|
US20240207374A1
(en)
|
2021-03-24 |
2024-06-27 |
Modernatx, Inc. |
Lipid nanoparticles containing polynucleotides encoding glucose-6-phosphatase and uses thereof
|
|
KR20220157778A
(ko)
*
|
2021-05-21 |
2022-11-29 |
원큐어젠 주식회사 |
세포 투과성 펩타이드 및 글루카곤 유사 펩타이드-1 수용체 작용제를 포함하는 복합체
|
|
EP4355882A2
(en)
|
2021-06-15 |
2024-04-24 |
Modernatx, Inc. |
Engineered polynucleotides for cell-type or microenvironment-specific expression
|
|
US20240376445A1
(en)
|
2021-06-22 |
2024-11-14 |
Modernatx, Inc. |
Polynucleotides encoding uridine diphosphate glycosyltransferase 1 family, polypeptide a1 for the treatment of crigler-najjar syndrome
|
|
US20250017867A1
(en)
|
2021-10-01 |
2025-01-16 |
Modernatx, Inc. |
Polynucleotides encoding relaxin for the treatment of fibrosis and/or cardiovascular disease
|
|
US20250282819A1
(en)
*
|
2021-10-13 |
2025-09-11 |
Camp Therapeutics Inc. |
Mitochondria-specific peptide that can be intracellularly delivered at nanomolar concentration, and use thereof
|
|
KR20230061895A
(ko)
*
|
2021-10-29 |
2023-05-09 |
주식회사 아이큐어비앤피 |
지질 나노입자 및 세포 투과성을 갖는 신규 펩타이드의 복합체
|
|
WO2023183909A2
(en)
|
2022-03-25 |
2023-09-28 |
Modernatx, Inc. |
Polynucleotides encoding fanconi anemia, complementation group proteins for the treatment of fanconi anemia
|
|
TW202412818A
(zh)
|
2022-07-26 |
2024-04-01 |
美商現代公司 |
用於暫時控制表現之經工程化多核苷酸
|
|
WO2024117321A1
(ko)
*
|
2022-12-01 |
2024-06-06 |
㈜에빅스젠 |
세포막 투과 펩티드 및 이를 포함하는 세포내 전달체
|
|
WO2024197033A1
(en)
|
2023-03-21 |
2024-09-26 |
Modernatx, Inc. |
Polynucleotides encoding relaxin for the treatment of heart failure
|
|
WO2024229321A1
(en)
|
2023-05-03 |
2024-11-07 |
Modernatx, Inc. |
Polynucleotides encoding cystic fibrosis transmembrane conductance regulator for the treatment of cystic fibrosis
|
|
JP7723457B2
(ja)
*
|
2023-07-03 |
2025-08-14 |
メスキュージェナシス株式会社 |
細胞膜透過性を有するペプチドおよびそのスクリーニング方法
|
|
WO2025072482A1
(en)
|
2023-09-27 |
2025-04-03 |
Modernatx, Inc. |
Immunoglobulin a protease polypeptides, polynucleotides, and uses thereof
|