ATE536187T1 - Hla-klasse-i- und -klasse-ii-bindende peptide und ihre verwendungen - Google Patents
Hla-klasse-i- und -klasse-ii-bindende peptide und ihre verwendungenInfo
- Publication number
- ATE536187T1 ATE536187T1 AT07023116T AT07023116T ATE536187T1 AT E536187 T1 ATE536187 T1 AT E536187T1 AT 07023116 T AT07023116 T AT 07023116T AT 07023116 T AT07023116 T AT 07023116T AT E536187 T1 ATE536187 T1 AT E536187T1
- Authority
- AT
- Austria
- Prior art keywords
- class
- binding peptides
- peptides
- hla
- hla class
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- 108700028369 Alleles Proteins 0.000 abstract 2
- 230000002163 immunogen Effects 0.000 abstract 2
- 102000003886 Glycoproteins Human genes 0.000 abstract 1
- 108090000288 Glycoproteins Proteins 0.000 abstract 1
- 230000006044 T cell activation Effects 0.000 abstract 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5158—Antigen-pulsed cells, e.g. T-cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/605—MHC molecules or ligands thereof
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US24235000P | 2000-10-19 | 2000-10-19 | |
US28562401P | 2001-04-20 | 2001-04-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE536187T1 true ATE536187T1 (de) | 2011-12-15 |
Family
ID=26935024
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT07023116T ATE536187T1 (de) | 2000-10-19 | 2001-10-18 | Hla-klasse-i- und -klasse-ii-bindende peptide und ihre verwendungen |
Country Status (5)
Country | Link |
---|---|
EP (2) | EP1455816A4 (de) |
AT (1) | ATE536187T1 (de) |
AU (1) | AU2001298049A1 (de) |
CA (1) | CA2425648A1 (de) |
WO (1) | WO2003040165A2 (de) |
Families Citing this family (67)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002048175A2 (en) * | 2000-12-13 | 2002-06-20 | Argonex Pharmaceuticals | Mhc class i associated peptides for prevention and treatment of tuberculosis |
WO2003008537A2 (en) * | 2001-04-06 | 2003-01-30 | Mannkind Corporation | Epitope sequences |
US20060222656A1 (en) | 2005-04-01 | 2006-10-05 | University Of Maryland, Baltimore | MAGE-A3/HPV 16 peptide vaccines for head and neck cancer |
US7049413B2 (en) * | 2001-05-18 | 2006-05-23 | Ludwig Institute For Cancer Research | MAGE-A3 peptides presented by HLA class II molecules |
WO2002094994A2 (en) | 2001-05-18 | 2002-11-28 | Mayo Foundation For Medical Education And Research | Chimeric antigen-specific t cell-activating polypeptides |
EP3184539A3 (de) | 2001-10-23 | 2017-09-13 | PSMA Development Company L.L.C. | Psma antikörper |
US20050215472A1 (en) | 2001-10-23 | 2005-09-29 | Psma Development Company, Llc | PSMA formulations and uses thereof |
JP5097400B2 (ja) * | 2003-09-03 | 2012-12-12 | デンドリセラピューティクス、インク. | 複合ワクチン |
IL157772A (en) * | 2003-09-04 | 2016-06-30 | Bmr Solutions Ltd | Compounds containing oligopeptide derived from turtle larvae and their use to encourage mammalian hemophysis |
WO2005037855A2 (en) * | 2003-10-17 | 2005-04-28 | Pecos Labs, Inc. | T cell epitopes useful in a yersinia pestis vaccine and as diagnostic tools and methods for identifying same |
EP1732598A4 (de) * | 2003-12-31 | 2009-08-26 | Pharmexa Inc | Auslösung von zellulären immunantworten gegen den humanen papillovirus unter verwendung von peptid und nucleinsäure-zusammensetzungen |
GB0406054D0 (en) * | 2004-03-17 | 2004-04-21 | Univ Nottingham Trent | Prostatic acid phosphatase antigens |
GB0716992D0 (en) | 2007-08-31 | 2007-10-10 | Immune Targeting Systems Its L | Influenza antigen delivery vectors and constructs |
GB0408164D0 (en) | 2004-04-13 | 2004-05-19 | Immune Targeting Systems Ltd | Antigen delivery vectors and constructs |
JP4761311B2 (ja) * | 2004-04-30 | 2011-08-31 | 日本電気株式会社 | Hla結合性ペプチド、それをコードするdna断片および組み換えベクター |
JP4731867B2 (ja) | 2004-10-01 | 2011-07-27 | 国立大学法人三重大学 | Cd8陽性の細胞傷害性tリンパ球の誘導方法 |
DE102004049223A1 (de) | 2004-10-08 | 2006-04-20 | Johannes-Gutenberg-Universität Mainz | Zubereitung zum Impfen, Impfverfahren und Verwendung einer Impf-Zubereitung |
EP1709971A1 (de) * | 2005-04-06 | 2006-10-11 | Ganymed Pharmaceuticals AG | Peptidantigene zur Verwendung in Prophylaxe, Behandlung und Diagnose von Poxvirusinfektionen |
AU2006259307B2 (en) * | 2005-06-17 | 2012-12-20 | Mannkind Corporation | Epitope analogues |
BRPI0504117A (pt) | 2005-09-05 | 2007-05-22 | Fundacao De Amparo A Pesquisa | epìtopos, combinação de epìtopos, usos de epìtopos ou sua combinação, composição, usos da composição, vacinas profiláticas anti-hiv-1, vacinas terapêuticas, método para a identificação de epìtopos e métodos para o tratamento ou prevenção |
DE602007005354D1 (de) * | 2006-01-25 | 2010-04-29 | Viro Pharmaceuticals Gmbh & Co | Humaner verstärker der viralen infektion (sevi) und seine anwendung |
US20100168034A1 (en) * | 2006-02-20 | 2010-07-01 | Ewha University-Industry Collaboration Foundation | Peptide having cell membrane penetrating activity |
EP1840133A1 (de) * | 2006-03-29 | 2007-10-03 | Global Biotech Development Corp. Ltd. | Neue immunomodulierende Oligopeptide |
US20080107668A1 (en) * | 2006-08-30 | 2008-05-08 | Immunotope, Inc. | Cytotoxic t-lymphocyte-inducing immunogens for prevention, treatment, and diagnosis of cancer |
EP2476697B1 (de) | 2006-10-17 | 2015-06-17 | Oncotherapy Science, Inc. | Peptidvakzinen für MPHOSPH1-Polypeptide exprimierenden Krebs |
US20090117140A1 (en) * | 2007-09-26 | 2009-05-07 | Mayumi Nakagawa | Human papilloma virus dominant CD4 T cell epitopes and uses thereof |
ES2627306T3 (es) * | 2007-11-20 | 2017-07-27 | Vianex S.A. | Análogos de péptido y conjugados de los mismos |
WO2009067584A1 (en) * | 2007-11-20 | 2009-05-28 | Duke University | Methods and compositions for modulating drug-polymer architecture, pharmacokinetics and biodistribution |
DK2234635T3 (en) * | 2007-12-19 | 2017-05-01 | Rhovac Aps | RhoC-based immunotherapy |
US20100166782A1 (en) * | 2008-07-25 | 2010-07-01 | Martha Karen Newell | Clip inhibitors and methods of modulating immune function |
US8975086B2 (en) | 2008-08-28 | 2015-03-10 | Oncotherapy Science, Inc. | Method for treating or preventing bladder cancer using the DEPDC1 polypeptide |
ES2574988T3 (es) | 2008-10-06 | 2016-06-23 | Yissum Research Development Company Of The Herbrew University Of Jerusalem Ltd. | Péptidos derivados de estimulantes de la VIH-1 integrasa que interfieren con la proteína Rev-integrasa |
JP5792630B2 (ja) | 2009-01-28 | 2015-10-14 | エピミューン,インコーポレイティド | Pan−dr結合ポリペプチドおよびその使用 |
JP5317336B2 (ja) * | 2009-02-23 | 2013-10-16 | 国立大学法人東北大学 | 質量分析装置を用いたタンパク質定量のための評価用ペプチド、人工標準タンパク質、及びタンパク質の定量方法 |
CA2756238A1 (en) * | 2009-04-02 | 2010-10-07 | Vaxon Biotech | Identification, optimization and use of cryptic hla-a24 epitopes for immunotherapy |
US8431530B2 (en) * | 2009-06-12 | 2013-04-30 | Morehouse School Of Medicine | Compositions and methods for treating aids or cancer by inhibiting the secretion of microparticles |
US9023802B2 (en) * | 2009-12-14 | 2015-05-05 | Immatics Biotechnologies Gmbh | HLA-binding peptides derived from prostate-associated antigenic molecules and methods of use thereof |
CN103732743B (zh) | 2011-08-12 | 2017-03-15 | 肿瘤疗法科学股份有限公司 | Mphosph1肽及包含它们的疫苗 |
GB201300683D0 (en) * | 2013-01-15 | 2013-02-27 | Apitope Int Nv | Peptide |
US10392611B2 (en) | 2013-05-30 | 2019-08-27 | Duke University | Polymer conjugates having reduced antigenicity and methods of using the same |
US10364451B2 (en) | 2013-05-30 | 2019-07-30 | Duke University | Polymer conjugates having reduced antigenicity and methods of using the same |
JP6692294B2 (ja) | 2013-07-31 | 2020-05-13 | バイオベンチャーズ・リミテッド・ライアビリティ・カンパニーBioVentures, LLC | 腫瘍関連糖鎖抗原を標的として癌を治療及び予防するための組成物及び方法 |
EP3140317B1 (de) | 2014-05-09 | 2020-04-15 | University Of Southampton | Peptidinduzierte nk-zellen-aktivierung |
US10385115B2 (en) | 2015-03-26 | 2019-08-20 | Duke University | Fibronectin type III domain-based fusion proteins |
GB201505305D0 (en) | 2015-03-27 | 2015-05-13 | Immatics Biotechnologies Gmbh | Novel Peptides and combination of peptides for use in immunotherapy against various tumors |
DK3273986T3 (da) | 2015-03-27 | 2024-02-12 | Immatics Biotechnologies Gmbh | Hidtil ukendte peptider og kombination af peptider til anvendelse ved immunterapi mod forskellige tumorer |
EP3319630A1 (de) | 2015-07-09 | 2018-05-16 | Intervacc AB | Impfstoff gegen s. suis-infektion |
JP6882782B2 (ja) | 2015-08-04 | 2021-06-02 | デューク ユニバーシティ | 遺伝子コードされた本質的に無秩序な送達用ステルスポリマーおよびその使用方法 |
GB201513921D0 (en) | 2015-08-05 | 2015-09-23 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against prostate cancer and other cancers |
EP3336186A4 (de) | 2015-08-12 | 2019-03-06 | OncoTherapy Science, Inc. | Depdc1-abgeleitetes peptid und impfstoff damit |
EP3360885A4 (de) | 2015-10-08 | 2019-04-24 | Oncotherapy Science, Inc. | Von mphosph1 abgeleitetes peptid und impfstoff damit |
GB201520570D0 (en) * | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
US11752213B2 (en) | 2015-12-21 | 2023-09-12 | Duke University | Surfaces having reduced non-specific binding and antigenicity |
US11467156B2 (en) | 2016-06-01 | 2022-10-11 | Duke University | Nonfouling biosensors |
RU2019110848A (ru) | 2016-09-14 | 2020-10-15 | Дьюк Юниверсити | Наночастицы на основе триблочных полипептидов для доставки гидрофильных лекарственных средств |
WO2018057847A1 (en) | 2016-09-23 | 2018-03-29 | Duke University | Unstructured non-repetitive polypeptides having lcst behavior |
WO2018085751A1 (en) * | 2016-11-07 | 2018-05-11 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Development of agonist epitopes of the human papillomavirus |
WO2018132732A1 (en) | 2017-01-12 | 2018-07-19 | Duke University | Genetically encoded lipid-polypeptide hybrid biomaterials that exhibit temperature triggered hierarchical self-assembly |
US20230241207A1 (en) * | 2017-04-03 | 2023-08-03 | Neon Therapeutics, Inc. | Protein antigens and uses thereof |
WO2018213320A1 (en) | 2017-05-15 | 2018-11-22 | Duke University | Recombinant production of hybrid lipid-biopolymer materials that self-assemble and encapsulate agents |
WO2019006374A1 (en) | 2017-06-30 | 2019-01-03 | Duke University | ORDER AND DISORDER AS A DESIGN PRINCIPLE FOR STIMULI-SENSITIVE BIOPOLYMER NETWORKS |
TW202019955A (zh) * | 2018-07-31 | 2020-06-01 | 德商英麥提克生物技術股份有限公司 | B*07 限制肽和肽組合的抗癌免疫治療和相關方法 |
EP3829622A4 (de) | 2018-08-02 | 2022-05-11 | Duke University | Doppel-agonisten-fusionsproteine |
US11512314B2 (en) | 2019-07-12 | 2022-11-29 | Duke University | Amphiphilic polynucleotides |
JP2022542119A (ja) * | 2019-07-24 | 2022-09-29 | アジェナス インコーポレイテッド | 抗原性ポリペプチドおよびその使用方法 |
NL2030990B1 (en) * | 2022-02-17 | 2023-09-01 | Academisch Ziekenhuis Leiden | T cell receptors directed against jchain and uses thereof |
CN117285597B (zh) * | 2023-11-27 | 2024-01-26 | 中国科学院烟台海岸带研究所 | 一种具有降尿酸功能的五肽kk5及其应用 |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4235871A (en) | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
US4722848A (en) | 1982-12-08 | 1988-02-02 | Health Research, Incorporated | Method for immunizing animals with synthetically modified vaccinia virus |
US4501728A (en) | 1983-01-06 | 1985-02-26 | Technology Unlimited, Inc. | Masking of liposomes from RES recognition |
US5019369A (en) | 1984-10-22 | 1991-05-28 | Vestar, Inc. | Method of targeting tumors in humans |
US4690915A (en) | 1985-08-08 | 1987-09-01 | The United States Of America As Represented By The Department Of Health And Human Services | Adoptive immunotherapy as a treatment modality in humans |
US4844893A (en) | 1986-10-07 | 1989-07-04 | Scripps Clinic And Research Foundation | EX vivo effector cell activation for target cell killing |
US4837028A (en) | 1986-12-24 | 1989-06-06 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
ATE342730T1 (de) | 1992-08-07 | 2006-11-15 | Pharmexa Inc | Hla bindepeptide und ihre verwendungen |
AU6359494A (en) | 1993-03-05 | 1994-09-26 | Epimmune, Inc. | Hla-a2.1 binding peptides and their uses |
US5679647A (en) | 1993-08-26 | 1997-10-21 | The Regents Of The University Of California | Methods and devices for immunizing a host against tumor-associated antigens through administration of naked polynucleotides which encode tumor-associated antigenic peptides |
US5804566A (en) | 1993-08-26 | 1998-09-08 | The Regents Of The University Of California | Methods and devices for immunizing a host through administration of naked polynucleotides with encode allergenic peptides |
DK0735893T3 (da) | 1993-09-14 | 2009-03-09 | Pharmexa Inc | PAN DR-bindende peptider til styrkelse af immunsvaret |
US5739118A (en) | 1994-04-01 | 1998-04-14 | Apollon, Inc. | Compositions and methods for delivery of genetic material |
US5736524A (en) | 1994-11-14 | 1998-04-07 | Merck & Co.,. Inc. | Polynucleotide tuberculosis vaccine |
US5922687A (en) | 1995-05-04 | 1999-07-13 | Board Of Trustees Of The Leland Stanford Junior University | Intracellular delivery of nucleic acids using pressure |
US6019974A (en) | 1996-01-26 | 2000-02-01 | Emory University | SPE-4 peptides |
EP0960204A4 (de) | 1996-07-26 | 2002-01-23 | Sloan Kettering Inst Cancer | Methoden und reagenzien zur genetischen immunisierung |
US6128946A (en) | 1997-06-26 | 2000-10-10 | Crane Nuclear, Inc. | Method and apparatus for on-line detection of leaky emergency shut down or other valves |
FR2771640B1 (fr) * | 1997-12-03 | 2000-02-11 | Inst Nat Sante Rech Med | Micelles mixtes de lipopeptides pour l'induction d'une reponse immunitaire et leurs utilisations a des fins therapeutiques |
AU6226100A (en) | 1999-07-19 | 2001-04-24 | Epimmune, Inc. | Inducing cellular immune responses to hepatitis c virus using peptide and nucleic acid compositions |
US7026443B1 (en) | 1999-12-10 | 2006-04-11 | Epimmune Inc. | Inducing cellular immune responses to human Papillomavirus using peptide and nucleic acid compositions |
-
2001
- 2001-10-18 CA CA002425648A patent/CA2425648A1/en not_active Abandoned
- 2001-10-18 AT AT07023116T patent/ATE536187T1/de active
- 2001-10-18 AU AU2001298049A patent/AU2001298049A1/en not_active Abandoned
- 2001-10-18 EP EP01274676A patent/EP1455816A4/de not_active Withdrawn
- 2001-10-18 WO PCT/US2001/051650 patent/WO2003040165A2/en active Search and Examination
- 2001-10-18 EP EP07023116A patent/EP1911461B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP1455816A2 (de) | 2004-09-15 |
EP1911461B1 (de) | 2011-12-07 |
AU2001298049A1 (en) | 2003-05-19 |
WO2003040165A3 (en) | 2004-06-24 |
EP1455816A4 (de) | 2007-03-28 |
WO2003040165A2 (en) | 2003-05-15 |
EP1911461A2 (de) | 2008-04-16 |
EP1911461A3 (de) | 2008-07-16 |
AU2001298049A8 (en) | 2005-11-03 |
CA2425648A1 (en) | 2002-04-19 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE536187T1 (de) | Hla-klasse-i- und -klasse-ii-bindende peptide und ihre verwendungen | |
ATE512666T1 (de) | Hla-bindende peptide und ihre verwendungen | |
DE69334076D1 (de) | Hla bindepeptide und ihre verwendungen | |
BR9406652A (pt) | Composição | |
DE69733352D1 (de) | Hla-a2.1 bindende peptide und deren verwendung | |
DK0941478T3 (da) | Assaymetode for peptidspecifikke T-celler | |
DE60142689D1 (de) | Verwendung prokariotischer pest-ähnlicher peptide zur verstärkung der immunogenität von antigenen | |
ATE493186T1 (de) | Zelltrennungszusammensetzungen und -verfahren | |
DK1553832T3 (da) | Præparater og fremgangsmåder til celleseparering | |
BR0017136A (pt) | Peptìdeos de ligação ao hla e seus usos. | |
ATE429247T1 (de) | Hla-bindende peptide und ihre verwendungen | |
DK1530637T3 (da) | Carlsberg-subtilisin-proteiner med nedsat immunogenitet | |
ATE551069T1 (de) | Mucin-fusionspolypeptid-vakzine, zusammensetzungen und ihre verwendung | |
DE60045776D1 (de) | Hla-bindungspeptide und ihre anwendungszwecke | |
WO2004007528A3 (en) | Novel compositions and methods for the generation of mhc class ii compounds by peptide exchange | |
WO2003091383A3 (fr) | Epitopes t de l'antigene epha2. | |
ATE399176T1 (de) | Nonapeptidische ny-eso-1 derivate und deren verwendung | |
WO2004011483A3 (en) | Isolated, ssx-2 and ssx-2 related peptides useful as hla binders and ctl epitopes, and uses thereof | |
EP1605039A4 (de) | Dendritische zelle mit alpha-glycosylceramid-derivat und antigen zur verwendung bei der unterdrückung von immunreaktionen | |
IL165674A0 (en) | Membrane-anchored B2 microglobulin covalently linked to MHC class I peptide epitopes |