ATE536187T1 - Hla-klasse-i- und -klasse-ii-bindende peptide und ihre verwendungen - Google Patents
Hla-klasse-i- und -klasse-ii-bindende peptide und ihre verwendungenInfo
- Publication number
- ATE536187T1 ATE536187T1 AT07023116T AT07023116T ATE536187T1 AT E536187 T1 ATE536187 T1 AT E536187T1 AT 07023116 T AT07023116 T AT 07023116T AT 07023116 T AT07023116 T AT 07023116T AT E536187 T1 ATE536187 T1 AT E536187T1
- Authority
- AT
- Austria
- Prior art keywords
- class
- binding peptides
- peptides
- hla
- hla class
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- 108700028369 Alleles Proteins 0.000 abstract 2
- 230000002163 immunogen Effects 0.000 abstract 2
- 102000003886 Glycoproteins Human genes 0.000 abstract 1
- 108090000288 Glycoproteins Proteins 0.000 abstract 1
- 230000006044 T cell activation Effects 0.000 abstract 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5158—Antigen-pulsed cells, e.g. T-cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/605—MHC molecules or ligands thereof
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24235000P | 2000-10-19 | 2000-10-19 | |
| US28562401P | 2001-04-20 | 2001-04-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE536187T1 true ATE536187T1 (de) | 2011-12-15 |
Family
ID=26935024
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07023116T ATE536187T1 (de) | 2000-10-19 | 2001-10-18 | Hla-klasse-i- und -klasse-ii-bindende peptide und ihre verwendungen |
Country Status (5)
| Country | Link |
|---|---|
| EP (2) | EP1455816A4 (de) |
| AT (1) | ATE536187T1 (de) |
| AU (1) | AU2001298049A1 (de) |
| CA (1) | CA2425648A1 (de) |
| WO (1) | WO2003040165A2 (de) |
Families Citing this family (70)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002048175A2 (en) * | 2000-12-13 | 2002-06-20 | Argonex Pharmaceuticals | Mhc class i associated peptides for prevention and treatment of tuberculosis |
| WO2003008537A2 (en) * | 2001-04-06 | 2003-01-30 | Mannkind Corporation | Epitope sequences |
| US20060222656A1 (en) | 2005-04-01 | 2006-10-05 | University Of Maryland, Baltimore | MAGE-A3/HPV 16 peptide vaccines for head and neck cancer |
| US7842480B2 (en) | 2001-05-18 | 2010-11-30 | Mayo Foundation For Medical Education And Research | Chimeric antigen-specific t cell-activating polypeptides |
| US7049413B2 (en) | 2001-05-18 | 2006-05-23 | Ludwig Institute For Cancer Research | MAGE-A3 peptides presented by HLA class II molecules |
| US20050215472A1 (en) | 2001-10-23 | 2005-09-29 | Psma Development Company, Llc | PSMA formulations and uses thereof |
| ES2559002T3 (es) | 2001-10-23 | 2016-02-10 | Psma Development Company, L.L.C. | Anticuerpos contra PSMA |
| JP5097400B2 (ja) * | 2003-09-03 | 2012-12-12 | デンドリセラピューティクス、インク. | 複合ワクチン |
| IL157772A (en) | 2003-09-04 | 2016-06-30 | Bmr Solutions Ltd | Compounds containing oligopeptide derived from turtle larvae and their use to encourage mammalian hemophysis |
| WO2005037855A2 (en) * | 2003-10-17 | 2005-04-28 | Pecos Labs, Inc. | T cell epitopes useful in a yersinia pestis vaccine and as diagnostic tools and methods for identifying same |
| AU2005222776A1 (en) * | 2003-12-31 | 2005-09-29 | Genimmune N.V. | Inducing cellular immune responses to human papillomavirus using peptide and nucleic acid compositions |
| GB0406054D0 (en) * | 2004-03-17 | 2004-04-21 | Univ Nottingham Trent | Prostatic acid phosphatase antigens |
| GB0408164D0 (en) | 2004-04-13 | 2004-05-19 | Immune Targeting Systems Ltd | Antigen delivery vectors and constructs |
| GB0716992D0 (en) | 2007-08-31 | 2007-10-10 | Immune Targeting Systems Its L | Influenza antigen delivery vectors and constructs |
| EP2559763B1 (de) * | 2004-04-30 | 2017-02-15 | NEC Corporation | HLA bindendes Peptid, dessen vorstufe, dafür codierendes DNA-Fragment und rekombinanter Vektor |
| JP4731867B2 (ja) | 2004-10-01 | 2011-07-27 | 国立大学法人三重大学 | Cd8陽性の細胞傷害性tリンパ球の誘導方法 |
| DE102004049223A1 (de) | 2004-10-08 | 2006-04-20 | Johannes-Gutenberg-Universität Mainz | Zubereitung zum Impfen, Impfverfahren und Verwendung einer Impf-Zubereitung |
| EP1709971A1 (de) * | 2005-04-06 | 2006-10-11 | Ganymed Pharmaceuticals AG | Peptidantigene zur Verwendung in Prophylaxe, Behandlung und Diagnose von Poxvirusinfektionen |
| EP2371850A3 (de) * | 2005-06-17 | 2012-08-01 | Mannkind Corporation | Epitopanaloge |
| BRPI0504117A (pt) * | 2005-09-05 | 2007-05-22 | Fundacao De Amparo A Pesquisa | epìtopos, combinação de epìtopos, usos de epìtopos ou sua combinação, composição, usos da composição, vacinas profiláticas anti-hiv-1, vacinas terapêuticas, método para a identificação de epìtopos e métodos para o tratamento ou prevenção |
| US8299031B2 (en) * | 2006-01-25 | 2012-10-30 | Viro Pharmaceuticals Gmbh & Co. Kg | Human semen enhancer of viral infection peptides (SEVI) and their use |
| WO2007097561A1 (en) * | 2006-02-20 | 2007-08-30 | Ewha University - Industry Collaboration Foundation | Peptide having cell membrane penetrating activity |
| EP1840133A1 (de) * | 2006-03-29 | 2007-10-03 | Global Biotech Development Corp. Ltd. | Neue immunomodulierende Oligopeptide |
| US20080107668A1 (en) * | 2006-08-30 | 2008-05-08 | Immunotope, Inc. | Cytotoxic t-lymphocyte-inducing immunogens for prevention, treatment, and diagnosis of cancer |
| BRPI0717651A2 (pt) | 2006-10-17 | 2013-12-24 | Oncotherapy Science Inc | Vacinas de peptídeo para cânceres que expressam polipeptídeos mphosph1 ou depdc1 |
| US20090117140A1 (en) * | 2007-09-26 | 2009-05-07 | Mayumi Nakagawa | Human papilloma virus dominant CD4 T cell epitopes and uses thereof |
| WO2009067584A1 (en) * | 2007-11-20 | 2009-05-28 | Duke University | Methods and compositions for modulating drug-polymer architecture, pharmacokinetics and biodistribution |
| PL2227486T3 (pl) * | 2007-11-20 | 2017-09-29 | Vianex S.A. | Analogi peptydowe i ich koniugaty |
| DK2234635T3 (en) * | 2007-12-19 | 2017-05-01 | Rhovac Aps | RhoC-based immunotherapy |
| US20100166782A1 (en) * | 2008-07-25 | 2010-07-01 | Martha Karen Newell | Clip inhibitors and methods of modulating immune function |
| EP2362904B1 (de) | 2008-08-28 | 2016-11-16 | Oncotherapy Science, Inc. | Verfahren zum screenen von verbindungen zur verwendung bei der hemmung der depdc1 - znf224 bindung |
| EP2334318B1 (de) | 2008-10-06 | 2016-02-10 | Yissum Research Development Company of The Hebrew University of Jerusalem Ltd. | Hiv-1 integrase abgeleitete, stimulatorische peptide, die mit der bindung von integrase - rev protein interferieren |
| US9249187B2 (en) | 2009-01-28 | 2016-02-02 | Epimmune Inc. | Pan-DR binding polypeptides and uses thereof |
| JP5317336B2 (ja) * | 2009-02-23 | 2013-10-16 | 国立大学法人東北大学 | 質量分析装置を用いたタンパク質定量のための評価用ペプチド、人工標準タンパク質、及びタンパク質の定量方法 |
| ES2608715T3 (es) * | 2009-04-02 | 2017-04-12 | Vaxon Biotech | Identificación, optimización y uso de epítopos HLA-A24 crípticos para inmunoterapia |
| US8431530B2 (en) * | 2009-06-12 | 2013-04-30 | Morehouse School Of Medicine | Compositions and methods for treating aids or cancer by inhibiting the secretion of microparticles |
| US9023802B2 (en) * | 2009-12-14 | 2015-05-05 | Immatics Biotechnologies Gmbh | HLA-binding peptides derived from prostate-associated antigenic molecules and methods of use thereof |
| JP5564730B2 (ja) | 2011-08-12 | 2014-08-06 | オンコセラピー・サイエンス株式会社 | Mphosph1ペプチドおよびそれを含むワクチン |
| GB201300683D0 (en) * | 2013-01-15 | 2013-02-27 | Apitope Int Nv | Peptide |
| US10364451B2 (en) | 2013-05-30 | 2019-07-30 | Duke University | Polymer conjugates having reduced antigenicity and methods of using the same |
| US10392611B2 (en) | 2013-05-30 | 2019-08-27 | Duke University | Polymer conjugates having reduced antigenicity and methods of using the same |
| US10272144B2 (en) | 2013-07-31 | 2019-04-30 | Bioventures, Llc | Compositions for and methods of treating and preventing targeting tumor associated carbohydrate antigens |
| US10995116B2 (en) | 2014-05-09 | 2021-05-04 | University Of Southampton | Peptide-induced NK cell activation |
| US10385115B2 (en) | 2015-03-26 | 2019-08-20 | Duke University | Fibronectin type III domain-based fusion proteins |
| DK3388075T5 (da) | 2015-03-27 | 2024-09-23 | Immatics Biotechnologies Gmbh | Hidtil ukendte peptider og kombination af peptider til anvendelse ved immunterapi mod forskellige tumorer |
| GB201505305D0 (en) | 2015-03-27 | 2015-05-13 | Immatics Biotechnologies Gmbh | Novel Peptides and combination of peptides for use in immunotherapy against various tumors |
| US11155585B2 (en) * | 2015-07-09 | 2021-10-26 | Intervacc Ab | Vaccine against S. suis infection |
| CA2994279A1 (en) | 2015-08-04 | 2017-02-09 | Duke University | Genetically encoded intrinsically disordered stealth polymers for delivery and methods of using same |
| GB201513921D0 (en) | 2015-08-05 | 2015-09-23 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against prostate cancer and other cancers |
| WO2017026503A1 (ja) | 2015-08-12 | 2017-02-16 | オンコセラピー・サイエンス株式会社 | Depdc1由来ペプチドおよびそれを含むワクチン |
| US10793599B2 (en) | 2015-10-08 | 2020-10-06 | Oncotherapy Science, Inc. | MPHOSPH1-derived peptide, and vaccine including same |
| GB201520570D0 (en) * | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
| US11752213B2 (en) | 2015-12-21 | 2023-09-12 | Duke University | Surfaces having reduced non-specific binding and antigenicity |
| WO2017210476A1 (en) | 2016-06-01 | 2017-12-07 | Duke University | Nonfouling biosensors |
| WO2018053201A1 (en) | 2016-09-14 | 2018-03-22 | Duke University | Triblock polypeptide-based nanoparticles for the delivery of hydrophilic drugs |
| JP2020500150A (ja) | 2016-09-23 | 2020-01-09 | デューク ユニバーシティ | 下限臨界溶液温度挙動を有する非反復かつ非構造的ポリペプチド |
| WO2018085751A1 (en) * | 2016-11-07 | 2018-05-11 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Development of agonist epitopes of the human papillomavirus |
| US11648200B2 (en) | 2017-01-12 | 2023-05-16 | Duke University | Genetically encoded lipid-polypeptide hybrid biomaterials that exhibit temperature triggered hierarchical self-assembly |
| CN118370809A (zh) * | 2017-04-03 | 2024-07-23 | 百欧恩泰美国公司 | 蛋白质抗原及其用途 |
| WO2018213320A1 (en) | 2017-05-15 | 2018-11-22 | Duke University | Recombinant production of hybrid lipid-biopolymer materials that self-assemble and encapsulate agents |
| US11680083B2 (en) | 2017-06-30 | 2023-06-20 | Duke University | Order and disorder as a design principle for stimuli-responsive biopolymer networks |
| WO2019147954A1 (en) | 2018-01-26 | 2019-08-01 | Duke University | Albumin binding peptide-drug (aibiped) conjugates and methods of making and using same |
| US12257308B2 (en) | 2018-04-30 | 2025-03-25 | Duke University | Stimuli-responsive PEG-like polymer-based drug delivery platform |
| TW202019955A (zh) | 2018-07-31 | 2020-06-01 | 德商英麥提克生物技術股份有限公司 | B*07 限制肽和肽組合的抗癌免疫治療和相關方法 |
| US11649275B2 (en) | 2018-08-02 | 2023-05-16 | Duke University | Dual agonist fusion proteins |
| US11512314B2 (en) | 2019-07-12 | 2022-11-29 | Duke University | Amphiphilic polynucleotides |
| CA3148253A1 (en) * | 2019-07-24 | 2021-01-28 | Agenus Inc. | Antigenic polypeptides and methods of use thereof |
| NL2030990B1 (en) * | 2022-02-17 | 2023-09-01 | Academisch Ziekenhuis Leiden | T cell receptors directed against jchain and uses thereof |
| EP4486768A4 (de) * | 2022-03-02 | 2026-03-04 | Univ California | Menschliche t-zell-rezeptorpaare, die mit hla-a*02:01-beschränkten epitopen der humanen prostatasäurephosphatase (pap) reagieren |
| CN117285597B (zh) * | 2023-11-27 | 2024-01-26 | 中国科学院烟台海岸带研究所 | 一种具有降尿酸功能的五肽kk5及其应用 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4235871A (en) | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
| US4722848A (en) | 1982-12-08 | 1988-02-02 | Health Research, Incorporated | Method for immunizing animals with synthetically modified vaccinia virus |
| US4501728A (en) | 1983-01-06 | 1985-02-26 | Technology Unlimited, Inc. | Masking of liposomes from RES recognition |
| US5019369A (en) | 1984-10-22 | 1991-05-28 | Vestar, Inc. | Method of targeting tumors in humans |
| US4690915A (en) | 1985-08-08 | 1987-09-01 | The United States Of America As Represented By The Department Of Health And Human Services | Adoptive immunotherapy as a treatment modality in humans |
| US4844893A (en) | 1986-10-07 | 1989-07-04 | Scripps Clinic And Research Foundation | EX vivo effector cell activation for target cell killing |
| US4837028A (en) | 1986-12-24 | 1989-06-06 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
| EP1704868A1 (de) | 1992-08-07 | 2006-09-27 | Pharmexa Inc. | HLA Bindepeptide und ihre Verwendungen |
| JP3908271B2 (ja) | 1993-03-05 | 2007-04-25 | エピミューン,インコーポレイティド | Hla−a2.1結合ペプチドおよびそれらの使用 |
| US5804566A (en) | 1993-08-26 | 1998-09-08 | The Regents Of The University Of California | Methods and devices for immunizing a host through administration of naked polynucleotides with encode allergenic peptides |
| US5679647A (en) | 1993-08-26 | 1997-10-21 | The Regents Of The University Of California | Methods and devices for immunizing a host against tumor-associated antigens through administration of naked polynucleotides which encode tumor-associated antigenic peptides |
| PT735893E (pt) | 1993-09-14 | 2009-03-06 | Pharmexa Inc | Péptidos que se ligam aos alelos pan dr para aumentar a resposta imunitária |
| US5739118A (en) | 1994-04-01 | 1998-04-14 | Apollon, Inc. | Compositions and methods for delivery of genetic material |
| US5736524A (en) | 1994-11-14 | 1998-04-07 | Merck & Co.,. Inc. | Polynucleotide tuberculosis vaccine |
| US5922687A (en) | 1995-05-04 | 1999-07-13 | Board Of Trustees Of The Leland Stanford Junior University | Intracellular delivery of nucleic acids using pressure |
| US6019974A (en) | 1996-01-26 | 2000-02-01 | Emory University | SPE-4 peptides |
| CA2262006A1 (en) | 1996-07-26 | 1998-02-05 | Sloan-Kettering Institute For Cancer Research | Method and reagents for genetic immunization |
| US6128946A (en) | 1997-06-26 | 2000-10-10 | Crane Nuclear, Inc. | Method and apparatus for on-line detection of leaky emergency shut down or other valves |
| FR2771640B1 (fr) * | 1997-12-03 | 2000-02-11 | Inst Nat Sante Rech Med | Micelles mixtes de lipopeptides pour l'induction d'une reponse immunitaire et leurs utilisations a des fins therapeutiques |
| CA2377525A1 (en) | 1999-07-19 | 2001-03-29 | Epimmune Inc. | Inducing cellular immune responses to hepatitis c virus using peptide and nucleic acid compositions |
| US7026443B1 (en) | 1999-12-10 | 2006-04-11 | Epimmune Inc. | Inducing cellular immune responses to human Papillomavirus using peptide and nucleic acid compositions |
-
2001
- 2001-10-18 EP EP01274676A patent/EP1455816A4/de not_active Withdrawn
- 2001-10-18 CA CA002425648A patent/CA2425648A1/en not_active Abandoned
- 2001-10-18 AT AT07023116T patent/ATE536187T1/de active
- 2001-10-18 WO PCT/US2001/051650 patent/WO2003040165A2/en not_active Ceased
- 2001-10-18 AU AU2001298049A patent/AU2001298049A1/en not_active Abandoned
- 2001-10-18 EP EP07023116A patent/EP1911461B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU2001298049A8 (en) | 2005-11-03 |
| AU2001298049A1 (en) | 2003-05-19 |
| CA2425648A1 (en) | 2002-04-19 |
| EP1455816A2 (de) | 2004-09-15 |
| WO2003040165A2 (en) | 2003-05-15 |
| EP1911461B1 (de) | 2011-12-07 |
| WO2003040165A3 (en) | 2004-06-24 |
| EP1455816A4 (de) | 2007-03-28 |
| EP1911461A2 (de) | 2008-04-16 |
| EP1911461A3 (de) | 2008-07-16 |
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