ATE429247T1 - Hla-bindende peptide und ihre verwendungen - Google Patents
Hla-bindende peptide und ihre verwendungenInfo
- Publication number
- ATE429247T1 ATE429247T1 AT99928792T AT99928792T ATE429247T1 AT E429247 T1 ATE429247 T1 AT E429247T1 AT 99928792 T AT99928792 T AT 99928792T AT 99928792 T AT99928792 T AT 99928792T AT E429247 T1 ATE429247 T1 AT E429247T1
- Authority
- AT
- Austria
- Prior art keywords
- hla
- peptides
- binding peptides
- immunogenic
- allele
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- 108700028369 Alleles Proteins 0.000 abstract 2
- 230000002163 immunogen Effects 0.000 abstract 2
- 102000003886 Glycoproteins Human genes 0.000 abstract 1
- 108090000288 Glycoproteins Proteins 0.000 abstract 1
- 230000006044 T cell activation Effects 0.000 abstract 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70539—MHC-molecules, e.g. HLA-molecules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9858498A | 1998-06-17 | 1998-06-17 | |
| PCT/US1999/013789 WO1999065522A1 (en) | 1998-06-17 | 1999-06-17 | Hla binding peptides and their uses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE429247T1 true ATE429247T1 (de) | 2009-05-15 |
Family
ID=22269985
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99928792T ATE429247T1 (de) | 1998-06-17 | 1999-06-17 | Hla-bindende peptide und ihre verwendungen |
Country Status (8)
| Country | Link |
|---|---|
| EP (2) | EP1089757B1 (de) |
| JP (2) | JP2002518346A (de) |
| AT (1) | ATE429247T1 (de) |
| AU (1) | AU4577899A (de) |
| CA (1) | CA2330824A1 (de) |
| DE (1) | DE69940774D1 (de) |
| ES (1) | ES2326146T3 (de) |
| WO (1) | WO1999065522A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9340577B2 (en) | 1992-08-07 | 2016-05-17 | Epimmune Inc. | HLA binding motifs and peptides and their uses |
| DE19925199A1 (de) | 1999-06-01 | 2000-12-07 | Medigene Ag | Zytotoxische T-Zellepitope des Papillomavirus L1-Proteins und ihre Verwendung in Diagnostik und Therapie |
| DE19925235A1 (de) | 1999-06-01 | 2000-12-07 | Medigene Ag | Zytotoxische T-Zellepitope des Papillomavirus L1-Proteins und ihre Verwendung in Diagnostik und Therapie |
| GB9923309D0 (en) * | 1999-10-01 | 1999-12-08 | Glaxo Group Ltd | Assay |
| EP1237564A4 (de) * | 1999-12-10 | 2005-05-04 | Epimmune Inc | Induktion zellulärer immunantworten gegen p53 mittels peptid und nukleinsäure-verbindungen |
| US7462354B2 (en) | 1999-12-28 | 2008-12-09 | Pharmexa Inc. | Method and system for optimizing minigenes and peptides encoded thereby |
| EP1766393A4 (de) * | 2004-05-07 | 2008-06-18 | Beckman Coulter Inc | Mhc-brückensystem zum nachweis der ctl-vermittelten lyse antigenpräsentierender zellen |
| EP2391635B1 (de) | 2009-01-28 | 2017-04-26 | Epimmune Inc. | Pan-dr-bindende polypeptide und verwendungen davon |
| CA2919835A1 (en) | 2013-07-31 | 2015-02-05 | Board Of Trustees Of The University Of Arkansas | Compositions for and methods of treating and preventing cancer targeting tumor associated carbohydrate antigens |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4235871A (en) | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
| US4722848A (en) | 1982-12-08 | 1988-02-02 | Health Research, Incorporated | Method for immunizing animals with synthetically modified vaccinia virus |
| US4501728A (en) | 1983-01-06 | 1985-02-26 | Technology Unlimited, Inc. | Masking of liposomes from RES recognition |
| US5019369A (en) | 1984-10-22 | 1991-05-28 | Vestar, Inc. | Method of targeting tumors in humans |
| US4690915A (en) | 1985-08-08 | 1987-09-01 | The United States Of America As Represented By The Department Of Health And Human Services | Adoptive immunotherapy as a treatment modality in humans |
| US4844893A (en) | 1986-10-07 | 1989-07-04 | Scripps Clinic And Research Foundation | EX vivo effector cell activation for target cell killing |
| US4837028A (en) | 1986-12-24 | 1989-06-06 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
| DE69031305T2 (de) | 1989-11-03 | 1998-03-26 | Univ Vanderbilt | Verfahren zur in vivo-verabreichung von funktionsfähigen fremden genen |
| US5279833A (en) | 1990-04-04 | 1994-01-18 | Yale University | Liposomal transfection of nucleic acids into animal cells |
| US5204253A (en) | 1990-05-29 | 1993-04-20 | E. I. Du Pont De Nemours And Company | Method and apparatus for introducing biological substances into living cells |
| US5972351A (en) * | 1992-04-03 | 1999-10-26 | Isis Innovation Limited | Plasmodium falciparum MHC class I-restricted CTL epitopes derived from pre-erythrocytic stage antigens |
| ES2139012T3 (es) * | 1992-05-26 | 2000-02-01 | Univ Leiden | Peptidos de la proteina p53 humana destinados para ser utilizados en composiciones que inducen una reaccion en los linfocitos t humanos, y linfocitos t citotoxicos especificos de la proteina p53 humana. |
| AU4528493A (en) | 1992-06-04 | 1994-01-04 | Regents Of The University Of California, The | In vivo gene therapy with intron-free sequence of interest |
| ATE342730T1 (de) * | 1992-08-07 | 2006-11-15 | Pharmexa Inc | Hla bindepeptide und ihre verwendungen |
| WO1994020127A1 (en) * | 1993-03-05 | 1994-09-15 | Cytel Corporation | Hla-a2.1 binding peptides and their uses |
| EP0735893B1 (de) | 1993-09-14 | 2008-11-26 | Pharmexa Inc. | Pan dr-bindeproteinen zur erhöhung der immunantwort |
| US5686068A (en) * | 1994-03-24 | 1997-11-11 | Ludwig Institute For Cancer Research | Isolated peptides derived from MAGE-2, cytolytic T cells specific to complexes of peptide and HLA-A2 molecules, and uses thereof |
| US6071890A (en) | 1994-12-09 | 2000-06-06 | Genzyme Corporation | Organ-specific targeting of cationic amphiphile/DNA complexes for gene therapy |
| JPH10510988A (ja) * | 1994-12-14 | 1998-10-27 | ザ スクリップス リサーチ インスティテュート | 腫瘍−特異的細胞毒性t細胞のインビボ活性化 |
| US5840839A (en) * | 1996-02-09 | 1998-11-24 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Alternative open reading frame DNA of a normal gene and a novel human cancer antigen encoded therein |
| DK0900380T3 (da) * | 1996-04-26 | 2003-11-03 | Seed Capital Investments | Fremgangsmåde til udvælgelse og fremstilling af T-celle-peptid-epitoper og vacciner indeholdende disse udvalgte epitoper |
-
1999
- 1999-06-17 DE DE69940774T patent/DE69940774D1/de not_active Expired - Lifetime
- 1999-06-17 EP EP99928792A patent/EP1089757B1/de not_active Expired - Lifetime
- 1999-06-17 EP EP08018213A patent/EP2036573A1/de not_active Withdrawn
- 1999-06-17 CA CA002330824A patent/CA2330824A1/en not_active Abandoned
- 1999-06-17 ES ES99928792T patent/ES2326146T3/es not_active Expired - Lifetime
- 1999-06-17 WO PCT/US1999/013789 patent/WO1999065522A1/en not_active Ceased
- 1999-06-17 AU AU45778/99A patent/AU4577899A/en not_active Abandoned
- 1999-06-17 AT AT99928792T patent/ATE429247T1/de not_active IP Right Cessation
- 1999-06-17 JP JP2000554400A patent/JP2002518346A/ja active Pending
-
2010
- 2010-01-12 JP JP2010004446A patent/JP2010090167A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP1089757A4 (de) | 2002-10-30 |
| AU4577899A (en) | 2000-01-05 |
| EP1089757B1 (de) | 2009-04-22 |
| ES2326146T3 (es) | 2009-10-01 |
| CA2330824A1 (en) | 1999-12-23 |
| EP1089757A1 (de) | 2001-04-11 |
| EP2036573A1 (de) | 2009-03-18 |
| JP2002518346A (ja) | 2002-06-25 |
| DE69940774D1 (de) | 2009-06-04 |
| WO1999065522A1 (en) | 1999-12-23 |
| JP2010090167A (ja) | 2010-04-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |