BR0017136A - Peptìdeos de ligação ao hla e seus usos. - Google Patents
Peptìdeos de ligação ao hla e seus usos.Info
- Publication number
- BR0017136A BR0017136A BR0017136-0A BR0017136A BR0017136A BR 0017136 A BR0017136 A BR 0017136A BR 0017136 A BR0017136 A BR 0017136A BR 0017136 A BR0017136 A BR 0017136A
- Authority
- BR
- Brazil
- Prior art keywords
- hla
- peptides
- binding peptides
- allele
- binding
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 5
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 4
- 230000002163 immunogen Effects 0.000 abstract 2
- 102000003886 Glycoproteins Human genes 0.000 abstract 1
- 108090000288 Glycoproteins Proteins 0.000 abstract 1
- 230000006044 T cell activation Effects 0.000 abstract 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
"PEPTìDEOS DE LIGAçãO AO HLA E SEUS USOS". A presente invenção proporciona os meios e os métodos para selecionar peptídeos imunogênicos e as composições de peptídeos imunogênicos capazes de ligar especificamente glicoproteínas codificadas por alelos de HLA e induzir a ativação das células T em células T restringidas pelo alelo. Os peptídeos são úteis para fazer surgir uma resposta imunológica contra um antígeno desejado.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US2000/004655 WO2001062776A1 (en) | 2000-02-23 | 2000-02-23 | Hla binding peptides and their uses |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0017136A true BR0017136A (pt) | 2003-02-25 |
Family
ID=21741082
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0017136-0A BR0017136A (pt) | 2000-02-23 | 2000-02-23 | Peptìdeos de ligação ao hla e seus usos. |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP1263775A4 (pt) |
JP (1) | JP2003524016A (pt) |
CN (1) | CN1452634A (pt) |
AU (1) | AU2000232427A1 (pt) |
BR (1) | BR0017136A (pt) |
CA (1) | CA2400215A1 (pt) |
MX (1) | MXPA02008219A (pt) |
WO (1) | WO2001062776A1 (pt) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001000225A1 (en) * | 1999-06-29 | 2001-01-04 | Epimmune Inc. | Hla binding peptides and their uses |
AU2001242190A1 (en) * | 2000-03-31 | 2001-10-15 | Aventis Pasteur Limited | Immunogenic peptides derived from prostate-specific membrane antigen (psma) and uses thereof |
US20030113919A1 (en) * | 2001-08-17 | 2003-06-19 | Aventis Pasteur, Ltd. | Immunogenic targets for melanoma |
US8354380B2 (en) | 2004-06-17 | 2013-01-15 | Mannkind Corporation | NY-ESO-1 peptide analogs |
JP4475469B2 (ja) * | 2005-01-25 | 2010-06-09 | 日本電気株式会社 | Hla結合性ペプチド、それをコードするdna断片および組み換えベクター |
KR20080026181A (ko) * | 2005-06-17 | 2008-03-24 | 맨카인드 코포레이션 | 암세포 및 종양 기질에 발현된 우성 및 준우성 에피토프에대한 다가 면역반응을 유발하기 위한 방법 및 조성물 |
US7511118B2 (en) | 2005-06-17 | 2009-03-31 | Mannkind Corporation | PSMA peptide analogues |
CN1948333B (zh) * | 2005-10-14 | 2010-12-08 | 中国人民解放军第二军医大学 | 一种新的hPEBP4蛋白来源的HLA-A2限制性表位多肽及其应用 |
WO2008031064A1 (en) * | 2006-09-07 | 2008-03-13 | University Of South Florida | Hyd1 peptides as anti-cancer agents |
TW201008574A (en) | 2008-08-19 | 2010-03-01 | Oncotherapy Science Inc | INHBB epitope peptides and vaccines containing the same |
US9249187B2 (en) | 2009-01-28 | 2016-02-02 | Epimmune Inc. | Pan-DR binding polypeptides and uses thereof |
CA2793838C (en) | 2010-03-19 | 2019-09-17 | H. Lee Moffitt Cancer Center & Research Institute, Inc. | Integrin interaction inhibitors for the treatment of cancer |
US20130183376A1 (en) * | 2010-09-08 | 2013-07-18 | Saitama Medical University | Hepatitis c virus liposome vaccine |
WO2015048477A1 (en) | 2013-09-27 | 2015-04-02 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Cyclic peptide conjugates and methods of use |
CN110049774A (zh) | 2016-10-07 | 2019-07-23 | 恩特罗姆公司 | 肿瘤相关抗原表位的小型生物群序列变体 |
EP3522916A2 (en) | 2016-10-07 | 2019-08-14 | Enterome S.A. | Immunogenic compounds for cancer therapy |
EP3522915A2 (en) | 2016-10-07 | 2019-08-14 | Enterome S.A. | Immunogenic compounds for cancer therapy |
SG11201901979SA (en) | 2016-11-30 | 2019-04-29 | Advaxis Inc | Immunogenic compositions targeting recurrent cancer mutations and methods of use thereof |
CA3081710A1 (en) * | 2017-11-08 | 2019-05-16 | Advaxis, Inc. | Immunogenic heteroclitic peptides from cancer-associated proteins and methods of use thereof |
EP3773689B1 (en) | 2018-04-11 | 2022-11-09 | Enterome S.A. | Antigenic peptides for prevention and treatment of cancer |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE466869T1 (de) * | 1993-03-05 | 2010-05-15 | Epimmune Inc | Verfahren zur herstellung von immunogenen hla- a2.1-bindenden peptiden |
EP0907370B1 (en) * | 1996-03-21 | 2005-05-25 | Epimmune Inc. | Hla-a2.1 binding peptides and their uses |
AU3672597A (en) * | 1996-07-25 | 1998-02-20 | Johns Hopkins University, The | Novel genes of kaposi's sarcoma associated herpesvirus |
US5783567A (en) * | 1997-01-22 | 1998-07-21 | Pangaea Pharmaceuticals, Inc. | Microparticles for delivery of nucleic acid |
-
2000
- 2000-02-23 CA CA002400215A patent/CA2400215A1/en not_active Abandoned
- 2000-02-23 MX MXPA02008219A patent/MXPA02008219A/es unknown
- 2000-02-23 CN CN00819410A patent/CN1452634A/zh active Pending
- 2000-02-23 WO PCT/US2000/004655 patent/WO2001062776A1/en not_active Application Discontinuation
- 2000-02-23 JP JP2001562557A patent/JP2003524016A/ja active Pending
- 2000-02-23 EP EP00910314A patent/EP1263775A4/en not_active Withdrawn
- 2000-02-23 AU AU2000232427A patent/AU2000232427A1/en not_active Abandoned
- 2000-02-23 BR BR0017136-0A patent/BR0017136A/pt not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
JP2003524016A (ja) | 2003-08-12 |
WO2001062776A1 (en) | 2001-08-30 |
AU2000232427A1 (en) | 2001-09-03 |
MXPA02008219A (es) | 2005-06-30 |
CA2400215A1 (en) | 2001-08-30 |
CN1452634A (zh) | 2003-10-29 |
EP1263775A4 (en) | 2004-10-06 |
EP1263775A1 (en) | 2002-12-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR0017136A (pt) | Peptìdeos de ligação ao hla e seus usos. | |
BR9708220A (pt) | Peptìdios de ligação hla-a2.1 e seus usos | |
BR9406652A (pt) | Composição | |
AU2001298049A1 (en) | Hla class i and ii binding peptides and their uses | |
ATE512666T1 (de) | Hla-bindende peptide und ihre verwendungen | |
DK0941478T3 (da) | Assaymetode for peptidspecifikke T-celler | |
TR200101256T2 (tr) | DNA ile aşılamada geliştirmeler | |
ES2184769T3 (es) | Metodos y composiciones para microencapsulacion de antigenos para utilizar como vacunas. | |
BR9610802A (pt) | Método para melhoria da resposta imunológica método de preparo de células t de antígeno específico método para induzir tolerância de tecido de enxerto auxiliar de vacina meio de expansão e preparação de células dentríticas população de células dentríticas e respectivo método de preparo método para direcionar células-tronco hematopoiéticas ou células progenitoras a uma linhagem de células dentríticas | |
ES2177927T3 (es) | Composicion para provocar una reaccion inmunologica a un determinante antigenico no proteinico. | |
DK1267924T3 (da) | Immunterapeutiske metoder og sammensætninger | |
PT1272633E (pt) | Composições e métodos para imunoterapia baseada em células dendríticas | |
DE69720065D1 (de) | Therapeutische anwendungen von antigenen oder epitopen assoziert mit unvollständiger zellulärer peptidprozesierung , z.b.: exprimiert in rma-s zellen transfiziert mit b7-1 gen | |
DE69940774D1 (de) | Hla-bindende peptide und ihre verwendungen | |
AP2368A (en) | Novel expression vectors and uses thereof. | |
ES2308850T3 (es) | Anticuerpos para antigenos de celulas de langerhans de mamiferos y sus usos. | |
AU2000273396A1 (en) | Hla binding peptides and their uses | |
WO1999047102A3 (en) | Methods for enhanced antigen presentation on antigen-presenting cells and compositions produced thereby | |
ATE353226T1 (de) | Adjuvanszusammensetzung enthaltend fha oder ein fha-fragment in freier form | |
WO2002044205A3 (en) | Peptides from ag85 of mycobacterium and uses thereof | |
BR0016740A (pt) | Antìgenos de esporozoìto de cryptosporidium |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA10 | Dismissal: dismissal - article 33 of industrial property law | ||
B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |