JP2009526859A5 - - Google Patents
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- Publication number
- JP2009526859A5 JP2009526859A5 JP2008555361A JP2008555361A JP2009526859A5 JP 2009526859 A5 JP2009526859 A5 JP 2009526859A5 JP 2008555361 A JP2008555361 A JP 2008555361A JP 2008555361 A JP2008555361 A JP 2008555361A JP 2009526859 A5 JP2009526859 A5 JP 2009526859A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- amino
- ethyl
- dihydro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 CC(C)C(CC=C(C)C1)C1C(N(*)C1=C(**N*)*C=B*1)=O Chemical compound CC(C)C(CC=C(C)C1)C1C(N(*)C1=C(**N*)*C=B*1)=O 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77343506P | 2006-02-15 | 2006-02-15 | |
| US60/773,435 | 2006-02-15 | ||
| PCT/US2007/004053 WO2007095340A2 (en) | 2006-02-15 | 2007-02-15 | Small-molecule modulators of trp-p8 activity |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013006063A Division JP2013100325A (ja) | 2006-02-15 | 2013-01-17 | Ｔｒｐ−ｐ８活性の低分子モジュレーター |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009526859A JP2009526859A (ja) | 2009-07-23 |
| JP2009526859A5 true JP2009526859A5 (https=) | 2011-03-31 |
| JP5376957B2 JP5376957B2 (ja) | 2013-12-25 |
Family
ID=38372142
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008555361A Expired - Fee Related JP5376957B2 (ja) | 2006-02-15 | 2007-02-15 | Ｔｒｐ−ｐ８活性の低分子モジュレーター |
| JP2013006063A Pending JP2013100325A (ja) | 2006-02-15 | 2013-01-17 | Ｔｒｐ−ｐ８活性の低分子モジュレーター |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013006063A Pending JP2013100325A (ja) | 2006-02-15 | 2013-01-17 | Ｔｒｐ−ｐ８活性の低分子モジュレーター |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US7741355B2 (https=) |
| EP (2) | EP1986622B1 (https=) |
| JP (2) | JP5376957B2 (https=) |
| KR (1) | KR101457361B1 (https=) |
| CN (1) | CN101420942B (https=) |
| AU (1) | AU2007215015B2 (https=) |
| BR (1) | BRPI0707821A2 (https=) |
| CA (1) | CA2642297A1 (https=) |
| DK (1) | DK1986622T3 (https=) |
| ES (2) | ES2592959T3 (https=) |
| HR (1) | HRP20131224T1 (https=) |
| HU (1) | HUE029650T2 (https=) |
| MX (1) | MX2008010434A (https=) |
| PL (2) | PL2510925T3 (https=) |
| PT (1) | PT1986622E (https=) |
| RS (1) | RS53088B (https=) |
| RU (1) | RU2509079C2 (https=) |
| SI (1) | SI1986622T1 (https=) |
| TW (1) | TWI401248B (https=) |
| WO (1) | WO2007095340A2 (https=) |
| ZA (1) | ZA200807680B (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1663962A4 (en) * | 2003-08-22 | 2007-08-22 | Dendreon Corp | COMPOSITIONS AND METHODS FOR TREATING A DISEASE ASSOCIATED WITH TRP-P8 EXPRESSION |
| ES2592959T3 (es) | 2006-02-15 | 2016-12-02 | Dendreon Pharmaceuticals, Inc. | Moduladores de pequeñas moléculas de la actividad de TRP-P8 |
| US7772266B2 (en) * | 2006-02-15 | 2010-08-10 | Dendreon Corporation | Small-molecule modulators of TRP-P8 activity |
| EP3115045B1 (de) * | 2008-08-26 | 2020-08-12 | Basf Se | Nachweis und verwendung niedermolekularer modulatoren des kälte-menthol-rezeptors trpm8 |
| TWI692469B (zh) | 2012-11-09 | 2020-05-01 | 南韓商Ｌｇ化學股份有限公司 | Ｇｐｒ４０受體促效劑，製造該促效劑的方法以及含有該促效劑作爲活性劑的醫藥組成物 |
| JP2017518963A (ja) * | 2014-04-23 | 2017-07-13 | ザ プロクター アンド ギャンブル カンパニー | 生体表面付着組成物 |
| JP2018533567A (ja) * | 2015-10-22 | 2018-11-15 | ザ プロクター アンド ギャンブル カンパニー | クロマトグラフィー分離方法 |
| EP3365324A1 (en) * | 2015-10-22 | 2018-08-29 | The Procter and Gamble Company | Synthesis of cyclohexane carboxamide derivatives useful as sensates in consumer products |
| WO2020113094A1 (en) | 2018-11-30 | 2020-06-04 | Nuvation Bio Inc. | Pyrrole and pyrazole compounds and methods of use thereof |
| CN113677334B (zh) * | 2019-02-01 | 2024-04-09 | 马歇尔大学科研协会 | 瞬时受体电位melastatin 8(trpm8)拮抗剂和相关方法 |
| WO2021174475A1 (en) * | 2020-03-05 | 2021-09-10 | Givaudan Sa | Organic compounds |
| CN118829416A (zh) | 2022-02-02 | 2024-10-22 | 西姆莱斯股份公司 | 组合物(iii) |
| CN118695860A (zh) * | 2022-02-23 | 2024-09-24 | 拜奥海芬治疗学有限公司 | 作为kv7通道激活剂的吡唑基化合物 |
| CN115160184A (zh) * | 2022-08-08 | 2022-10-11 | 安徽丰乐香料有限责任公司 | N-对苯乙腈基薄荷烷基甲酰胺的制备方法 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3821221A (en) * | 1970-08-25 | 1974-06-28 | Delmar Chem | 1,2,3,6-tetrahydropyrimidine-2-one compounds and processes for makingthem |
| US4150052A (en) * | 1971-02-04 | 1979-04-17 | Wilkinson Sword Limited | N-substituted paramenthane carboxamides |
| US4153679A (en) * | 1972-04-18 | 1979-05-08 | Wilkinson Sword Limited | Acyclic carboxamides having a physiological cooling effect |
| BE802469A (fr) * | 1972-07-20 | 1974-01-18 | Wilkinson Sword Ltd | Perfectionnements apportes et/ou relatifs a des composes exercant un effet refrigerant physiologique et compositions contenant ceux-ci |
| US4296093A (en) * | 1973-04-16 | 1981-10-20 | Wilkinson Sword Limited | Cyclic carboxamides having a physiological cooling effect |
| GB1471894A (en) * | 1973-12-12 | 1977-04-27 | Wilkinson Sword Ltd | Compositions for application to or consumption by the body and containing a compound having a physiological cooling effect |
| JPS5888334A (ja) * | 1981-11-20 | 1983-05-26 | Takasago Corp | ３−ｌ−メントキシプロパン−１、２−ジオ−ル |
| DE4110973A1 (de) * | 1991-04-05 | 1992-10-08 | Haarmann & Reimer Gmbh | Mittel mit physiologischem kuehleffekt und fuer diese mittel geeignete wirksame verbindungen |
| FI945411L (fi) | 1992-05-18 | 1994-11-17 | Procter & Gamble | Viilentäviä koostumuksia |
| AU4530493A (en) | 1992-06-17 | 1994-01-04 | Procter & Gamble Company, The | Coolant compositions with reduced stinging |
| ES2105338T3 (es) * | 1992-10-29 | 1997-10-16 | Hisamitsu Pharmaceutical Co | Derivado de ciclohexanol, agente y composicion que contiene el mismo para impartir sensacion agradable de frio, procedimiento para la fabricacion del derivado e intermediario para su produccion. |
| IL135177A0 (en) * | 1997-10-02 | 2001-05-20 | Sankyo Co | Amidocarboxylic acid derivatives and pharmaceutical compositions containing the same |
| JP4017758B2 (ja) * | 1998-08-04 | 2007-12-05 | 高砂香料工業株式会社 | 冷感剤組成物 |
| JP2000247910A (ja) | 1999-02-26 | 2000-09-12 | Lion Corp | 外用剤組成物 |
| AU6453501A (en) * | 1999-02-26 | 2001-09-03 | Arena Pharmaceuticals, Inc. | Small molecule modulators of G protein-coupled receptor six |
| US6497659B1 (en) * | 1999-04-09 | 2002-12-24 | Spacelabs Medical, Inc. | System for identifying a cable transmitting a signal from a sensor to an electronic instrument |
| US6780443B1 (en) | 2000-02-04 | 2004-08-24 | Takasago International Corporation | Sensate composition imparting initial sensation upon contact |
| US6683192B2 (en) * | 2000-03-30 | 2004-01-27 | Curis, Inc. | Small organic molecule regulators of cell proliferation |
| EP1157617B1 (en) | 2000-05-23 | 2007-12-12 | Nestle Sa | Use of alpha-ketoenamine derivatives as cooling agents |
| US6497859B1 (en) * | 2000-11-17 | 2002-12-24 | Noville Inc. | Cooling agents, pharmaceutical compositions having cooling agents and processes for making and using same |
| KR20040004642A (ko) | 2001-05-23 | 2004-01-13 | 덴드레온 샌 디에고 엘엘씨 | 세포 표면 프로테아제에 의해 활성화되는 접합체 및 이의치료학적 용도 |
| US20040001801A1 (en) * | 2002-05-23 | 2004-01-01 | Corvas International, Inc. | Conjugates activated by cell surface proteases and therapeutic uses thereof |
| DE10259619A1 (de) * | 2002-12-18 | 2004-07-08 | Metagen Pharmaceuticals Gmbh | Verwendung einer TRPM8 aktivierenden Substanz zur Tumorbehandlung |
| WO2005002582A2 (en) * | 2003-07-02 | 2005-01-13 | Genentech, Inc. | Trp-p8 active compounds and therapeutic treatment methods |
| EP1663962A4 (en) * | 2003-08-22 | 2007-08-22 | Dendreon Corp | COMPOSITIONS AND METHODS FOR TREATING A DISEASE ASSOCIATED WITH TRP-P8 EXPRESSION |
| DE20313976U1 (de) * | 2003-09-09 | 2003-12-11 | Saueressig Gmbh + Co. | Walzenanordnung für das Prägen von bahnförmigen Materialien |
| US7169377B2 (en) * | 2003-10-15 | 2007-01-30 | Wei Edward T | Radioligands for the TRP-M8 receptor and methods therewith |
| US20050165025A1 (en) | 2004-01-22 | 2005-07-28 | Recordati Ireland Ltd. | Combination therapy with 5HT 1A and 5HT 1B-receptor antagonists |
| US20050187211A1 (en) * | 2004-02-23 | 2005-08-25 | Wei Edward T. | N-arylsalkyl-carboxamide compositions and methods |
| US20090105237A1 (en) * | 2005-05-27 | 2009-04-23 | Karen Ann Bell | Cooling compounds |
| ES2592959T3 (es) | 2006-02-15 | 2016-12-02 | Dendreon Pharmaceuticals, Inc. | Moduladores de pequeñas moléculas de la actividad de TRP-P8 |
-
2007
- 2007-02-15 ES ES12001852.8T patent/ES2592959T3/es active Active
- 2007-02-15 PT PT77508612T patent/PT1986622E/pt unknown
- 2007-02-15 ES ES07750861.2T patent/ES2441249T3/es active Active
- 2007-02-15 CA CA002642297A patent/CA2642297A1/en not_active Abandoned
- 2007-02-15 PL PL12001852T patent/PL2510925T3/pl unknown
- 2007-02-15 US US11/707,546 patent/US7741355B2/en not_active Expired - Fee Related
- 2007-02-15 CN CN200780013155.7A patent/CN101420942B/zh not_active Expired - Fee Related
- 2007-02-15 EP EP07750861.2A patent/EP1986622B1/en active Active
- 2007-02-15 PL PL07750861T patent/PL1986622T3/pl unknown
- 2007-02-15 RU RU2008136859/04A patent/RU2509079C2/ru not_active IP Right Cessation
- 2007-02-15 WO PCT/US2007/004053 patent/WO2007095340A2/en not_active Ceased
- 2007-02-15 DK DK07750861.2T patent/DK1986622T3/da active
- 2007-02-15 BR BRPI0707821-8A patent/BRPI0707821A2/pt not_active IP Right Cessation
- 2007-02-15 KR KR1020087022583A patent/KR101457361B1/ko not_active Expired - Fee Related
- 2007-02-15 RS RS20130579A patent/RS53088B/sr unknown
- 2007-02-15 HU HUE12001852A patent/HUE029650T2/en unknown
- 2007-02-15 HR HRP20131224TT patent/HRP20131224T1/hr unknown
- 2007-02-15 EP EP12001852.8A patent/EP2510925B8/en active Active
- 2007-02-15 AU AU2007215015A patent/AU2007215015B2/en not_active Ceased
- 2007-02-15 TW TW096105713A patent/TWI401248B/zh not_active IP Right Cessation
- 2007-02-15 MX MX2008010434A patent/MX2008010434A/es active IP Right Grant
- 2007-02-15 SI SI200731377T patent/SI1986622T1/sl unknown
- 2007-02-15 JP JP2008555361A patent/JP5376957B2/ja not_active Expired - Fee Related
-
2008
- 2008-09-05 ZA ZA2008/07680A patent/ZA200807680B/en unknown
-
2010
- 2010-06-08 US US12/796,587 patent/US8614243B2/en not_active Expired - Fee Related
-
2013
- 2013-01-17 JP JP2013006063A patent/JP2013100325A/ja active Pending
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