|
US4196265A
(en)
*
|
1977-06-15 |
1980-04-01 |
The Wistar Institute |
Method of producing antibodies
|
|
US4270537A
(en)
*
|
1979-11-19 |
1981-06-02 |
Romaine Richard A |
Automatic hypodermic syringe
|
|
US4816567A
(en)
*
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
JPS61134325A
(ja)
*
|
1984-12-04 |
1986-06-21 |
Teijin Ltd |
ハイブリツド抗体遺伝子の発現方法
|
|
JPS61176721A
(ja)
*
|
1985-01-31 |
1986-08-08 |
Mochizuki Motor Kk |
マンホ−ル蓋の開閉運搬装置
|
|
CA1288073C
(en)
*
|
1985-03-07 |
1991-08-27 |
Paul G. Ahlquist |
Rna transformation vector
|
|
US4596556A
(en)
*
|
1985-03-25 |
1986-06-24 |
Bioject, Inc. |
Hypodermic injection apparatus
|
|
US5618920A
(en)
*
|
1985-11-01 |
1997-04-08 |
Xoma Corporation |
Modular assembly of antibody genes, antibodies prepared thereby and use
|
|
CA1283827C
(en)
*
|
1986-12-18 |
1991-05-07 |
Giorgio Cirelli |
Appliance for injection of liquid formulations
|
|
GB8704027D0
(en)
*
|
1987-02-20 |
1987-03-25 |
Owen Mumford Ltd |
Syringe needle combination
|
|
US4790824A
(en)
*
|
1987-06-19 |
1988-12-13 |
Bioject, Inc. |
Non-invasive hypodermic injection device
|
|
US4941880A
(en)
*
|
1987-06-19 |
1990-07-17 |
Bioject, Inc. |
Pre-filled ampule and non-invasive hypodermic injection device assembly
|
|
US4940460A
(en)
*
|
1987-06-19 |
1990-07-10 |
Bioject, Inc. |
Patient-fillable and non-invasive hypodermic injection device assembly
|
|
US5316931A
(en)
*
|
1988-02-26 |
1994-05-31 |
Biosource Genetics Corp. |
Plant viral vectors having heterologous subgenomic promoters for systemic expression of foreign genes
|
|
US5339163A
(en)
*
|
1988-03-16 |
1994-08-16 |
Canon Kabushiki Kaisha |
Automatic exposure control device using plural image plane detection areas
|
|
US5223409A
(en)
*
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
|
GB8823869D0
(en)
*
|
1988-10-12 |
1988-11-16 |
Medical Res Council |
Production of antibodies
|
|
FR2638359A1
(fr)
*
|
1988-11-03 |
1990-05-04 |
Tino Dalto |
Guide de seringue avec reglage de la profondeur de penetration de l'aiguille dans la peau
|
|
US5530101A
(en)
*
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
DE3920358A1
(de)
*
|
1989-06-22 |
1991-01-17 |
Behringwerke Ag |
Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
|
|
US5064413A
(en)
*
|
1989-11-09 |
1991-11-12 |
Bioject, Inc. |
Needleless hypodermic injection device
|
|
US5312335A
(en)
*
|
1989-11-09 |
1994-05-17 |
Bioject Inc. |
Needleless hypodermic injection device
|
|
US5427908A
(en)
*
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
|
US5190521A
(en)
*
|
1990-08-22 |
1993-03-02 |
Tecnol Medical Products, Inc. |
Apparatus and method for raising a skin wheal and anesthetizing skin
|
|
US5633425A
(en)
*
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5545806A
(en)
*
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
|
US5770429A
(en)
*
|
1990-08-29 |
1998-06-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5661016A
(en)
*
|
1990-08-29 |
1997-08-26 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
US5625126A
(en)
*
|
1990-08-29 |
1997-04-29 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
ES2108048T3
(es)
*
|
1990-08-29 |
1997-12-16 |
Genpharm Int |
Produccion y utilizacion de animales inferiores transgenicos capaces de producir anticuerpos heterologos.
|
|
US5698426A
(en)
*
|
1990-09-28 |
1997-12-16 |
Ixsys, Incorporated |
Surface expression libraries of heteromeric receptors
|
|
US5527288A
(en)
*
|
1990-12-13 |
1996-06-18 |
Elan Medical Technologies Limited |
Intradermal drug delivery device and method for intradermal delivery of drugs
|
|
KR100240308B1
(ko)
*
|
1991-03-06 |
2000-01-15 |
플레믹 크리스티안 |
인간화된단클론성항체및혼성단클론성항체
|
|
ATE414768T1
(de)
*
|
1991-04-10 |
2008-12-15 |
Scripps Research Inst |
Bibliotheken heterodimerer rezeptoren mittels phagemiden
|
|
MX9204374A
(es)
*
|
1991-07-25 |
1993-03-01 |
Idec Pharma Corp |
Anticuerpo recombinante y metodo para su produccion.
|
|
GB9118204D0
(en)
*
|
1991-08-23 |
1991-10-09 |
Weston Terence E |
Needle-less injector
|
|
SE9102652D0
(sv)
*
|
1991-09-13 |
1991-09-13 |
Kabi Pharmacia Ab |
Injection needle arrangement
|
|
CA2078539C
(en)
*
|
1991-09-18 |
2005-08-02 |
Kenya Shitara |
Process for producing humanized chimera antibody
|
|
ES2136092T3
(es)
*
|
1991-09-23 |
1999-11-16 |
Medical Res Council |
Procedimientos para la produccion de anticuerpos humanizados.
|
|
GB9125979D0
(en)
*
|
1991-12-06 |
1992-02-05 |
Wellcome Found |
Antibody
|
|
US5667988A
(en)
*
|
1992-01-27 |
1997-09-16 |
The Scripps Research Institute |
Methods for producing antibody libraries using universal or randomized immunoglobulin light chains
|
|
NZ249677A
(en)
*
|
1992-02-19 |
1996-08-27 |
Schering Corp |
Monoclonal antibodies and compositions useful for treating il-4 diseases and intermediates for making such antibodies
|
|
US5328483A
(en)
*
|
1992-02-27 |
1994-07-12 |
Jacoby Richard M |
Intradermal injection device with medication and needle guard
|
|
US5965132A
(en)
*
|
1992-03-05 |
1999-10-12 |
Board Of Regents, The University Of Texas System |
Methods and compositions for targeting the vasculature of solid tumors
|
|
EP0627940B1
(en)
*
|
1992-03-05 |
2003-05-07 |
Board of Regents, The University of Texas System |
Use of immunoconjugates for the diagnosis and/or therapy of vascularized tumors
|
|
US6093399A
(en)
*
|
1992-03-05 |
2000-07-25 |
Board Of Regents, The University Of Texas System |
Methods and compositions for the specific coagulation of vasculature
|
|
US5877289A
(en)
*
|
1992-03-05 |
1999-03-02 |
The Scripps Research Institute |
Tissue factor compositions and ligands for the specific coagulation of vasculature
|
|
US5733743A
(en)
*
|
1992-03-24 |
1998-03-31 |
Cambridge Antibody Technology Limited |
Methods for producing members of specific binding pairs
|
|
US5383851A
(en)
*
|
1992-07-24 |
1995-01-24 |
Bioject Inc. |
Needleless hypodermic injection device
|
|
US5639641A
(en)
*
|
1992-09-09 |
1997-06-17 |
Immunogen Inc. |
Resurfacing of rodent antibodies
|
|
US5569189A
(en)
*
|
1992-09-28 |
1996-10-29 |
Equidyne Systems, Inc. |
hypodermic jet injector
|
|
US5334144A
(en)
*
|
1992-10-30 |
1994-08-02 |
Becton, Dickinson And Company |
Single use disposable needleless injector
|
|
US5693506A
(en)
*
|
1993-11-16 |
1997-12-02 |
The Regents Of The University Of California |
Process for protein production in plants
|
|
WO1995024176A1
(en)
*
|
1994-03-07 |
1995-09-14 |
Bioject, Inc. |
Ampule filling device
|
|
US5466220A
(en)
*
|
1994-03-08 |
1995-11-14 |
Bioject, Inc. |
Drug vial mixing and transfer device
|
|
US5599302A
(en)
*
|
1995-01-09 |
1997-02-04 |
Medi-Ject Corporation |
Medical injection system and method, gas spring thereof and launching device using gas spring
|
|
US5705154A
(en)
*
|
1995-03-08 |
1998-01-06 |
Schering Corporation |
Humanized monoclonal antibodies against human interleukin-4
|
|
US5702892A
(en)
*
|
1995-05-09 |
1997-12-30 |
The United States Of America As Represented By The Department Of Health And Human Services |
Phage-display of immunoglobulin heavy chain libraries
|
|
US5893397A
(en)
*
|
1996-01-12 |
1999-04-13 |
Bioject Inc. |
Medication vial/syringe liquid-transfer apparatus
|
|
US6042832A
(en)
*
|
1996-08-28 |
2000-03-28 |
Thomas Jefferson University |
Polypeptides fused with alfalfa mosaic virus or ilarvirus capsid proteins
|
|
US6103511A
(en)
*
|
1996-10-04 |
2000-08-15 |
University Of Georgia Research Foundation, Inc. |
Lichenase and coding sequences
|
|
US5993412A
(en)
*
|
1997-05-19 |
1999-11-30 |
Bioject, Inc. |
Injection apparatus
|
|
BR9812272A
(pt)
*
|
1997-08-05 |
2000-07-18 |
Stressgen Biotechnologies Corp |
Respostas imunológicas contra antìgenos de hpv, eliciadas por composições que compreendem um antìgeno de hpv e uma proteìna de tensão ou um vetor de expressão capaz de expressar essas proteìnas
|
|
US6037456A
(en)
*
|
1998-03-10 |
2000-03-14 |
Biosource Technologies, Inc. |
Process for isolating and purifying viruses, soluble proteins and peptides from plant sources
|
|
US6044555A
(en)
*
|
1998-05-04 |
2000-04-04 |
Keystone Powered Metal Company |
Method for producing fully dense powdered metal helical gear
|
|
KR20010072372A
(ko)
*
|
1998-08-11 |
2001-07-31 |
맥기 데이비드 알 |
식물조직의 간질액으로부터 단백질을 추출하는 방법
|
|
CN1248631A
(zh)
*
|
1998-09-24 |
2000-03-29 |
周国庆 |
一种免疫预防和免疫治疗性病和癌症的融合蛋白
|
|
US6734173B1
(en)
*
|
1999-10-20 |
2004-05-11 |
Johns Hopkins University |
HSP DNA vaccines
|
|
WO2001070663A2
(en)
*
|
2000-03-17 |
2001-09-27 |
Corixa Corporation |
Novel amphipathic aldehydes and their use as adjuvants and immunoeffectors
|
|
BRPI0111830B8
(pt)
*
|
2000-06-23 |
2021-05-25 |
American Cyanamid Co |
método de produção de partículas semelhantes ao vírus da influenza (vlps), vlps da influenza, vlps quiméricas, composições imunogênica e farmacêutica, e, usos de vlps da influenza e de vlps quiméricas
|
|
US20030104570A1
(en)
*
|
2000-06-26 |
2003-06-05 |
Cabezon Silva Teresa Elisa Virginia |
Triple fusion proteins comprising ubiquitin fused between thioredoxin and a polypeptide of interest
|
|
HRP20021015A2
(en)
*
|
2000-06-26 |
2004-02-29 |
Stressgen Biotechnologies Corp |
Human papilloma virus treatment
|
|
EP1363938B1
(en)
*
|
2000-08-03 |
2013-12-11 |
Johns Hopkins University |
Molecular vaccine linking an endoplasmic reticulum chaperone polypeptide to an antigen
|
|
CN1198840C
(zh)
*
|
2000-11-03 |
2005-04-27 |
浙江大学医学院附属第二医院 |
人类乳头瘤病毒11l1-e7重组蛋白及其应用
|
|
US20040170606A1
(en)
*
|
2002-06-07 |
2004-09-02 |
Palmer Kenneth E. |
Production of peptides in plants as viral coat protein fusions
|
|
EP1629090B1
(en)
*
|
2002-11-06 |
2014-03-05 |
iBio, Inc. |
Expression of foreign sequences in plants using trans-activation system
|
|
US7683238B2
(en)
*
|
2002-11-12 |
2010-03-23 |
iBio, Inc. and Fraunhofer USA, Inc. |
Production of pharmaceutically active proteins in sprouted seedlings
|
|
WO2004070016A2
(en)
*
|
2003-02-03 |
2004-08-19 |
Fraunhofer Usa Inc. |
System for expression of genes in plants
|
|
CN100393870C
(zh)
*
|
2003-05-05 |
2008-06-11 |
波依斯汤普森植物研究所 |
用于制备免疫保护性组合物的载体和来源于转基因植物的细胞
|
|
NZ542933A
(en)
*
|
2003-05-05 |
2009-08-28 |
Dow Agrosciences Llc |
Stable immunoprophylactic and therapeutic compositions derived from transgenic plant cells and methods for production
|
|
BRPI0410562B8
(pt)
*
|
2003-05-22 |
2021-05-25 |
Fralunhofer Usa Inc |
proteína de veículo e seu método de produção em uma planta, ácido nucleico isolado, vetor de expressão e célula hospedeira
|
|
US7566458B2
(en)
*
|
2003-06-16 |
2009-07-28 |
Medimmune, Llc |
Influenza hemagglutinin and neuraminidase variants
|
|
CZ297389B6
(cs)
*
|
2003-07-03 |
2006-11-15 |
Ústav Molekulární Biologie Rostlin Av Cr |
Fúzní protein pro vakcinaci proti lidskému papillomaviru a zpusob jeho produkce
|
|
JP5096743B2
(ja)
*
|
2003-11-10 |
2012-12-12 |
アイコン・ジェネティクス・ゲーエムベーハー |
Rnaウイルス由来植物発現システム
|
|
EP1769068B1
(en)
*
|
2004-02-20 |
2014-12-31 |
iBio, Inc. |
Systems and methods for clonal expression in plants
|
|
EP1749212A2
(en)
*
|
2004-04-23 |
2007-02-07 |
The University Of Georgia Research Foundation, Inc. |
Diagnostic assay for trypanosoma cruzi infection
|
|
EP1766059B1
(en)
*
|
2004-05-25 |
2012-07-11 |
MedImmune Vaccines, Inc. |
Influenza hemagglutinin and neuraminidase variants
|
|
EP1616959A1
(en)
*
|
2004-07-07 |
2006-01-18 |
Icon Genetics AG |
Biological safe transient protein expression in plants
|
|
JP2009526526A
(ja)
*
|
2006-02-13 |
2009-07-23 |
フラウンホーファー ユーエスエー, インコーポレイテッド |
インフルエンザ抗原、ワクチン組成物、および関連する方法
|
|
WO2008048344A2
(en)
*
|
2006-02-13 |
2008-04-24 |
Fraunhofer Usa, Inc. |
Bacillus anthracis antigens, vaccine compositions, and related methods
|
|
WO2009009759A2
(en)
*
|
2007-07-11 |
2009-01-15 |
Fraunhofer Usa, Inc. |
Yersinia pestis antigens, vaccine compositions, and related methods
|
|
BRPI0815662A2
(pt)
*
|
2007-08-20 |
2016-09-27 |
Fraunhofer Usa Inc |
vacinas, antígenos, composições, e métodos profilácticos e terapêuticos para gripe
|