JP2009524675A5 - - Google Patents

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Publication number
JP2009524675A5
JP2009524675A5 JP2008552415A JP2008552415A JP2009524675A5 JP 2009524675 A5 JP2009524675 A5 JP 2009524675A5 JP 2008552415 A JP2008552415 A JP 2008552415A JP 2008552415 A JP2008552415 A JP 2008552415A JP 2009524675 A5 JP2009524675 A5 JP 2009524675A5
Authority
JP
Japan
Prior art keywords
bioavailability
tetracycline compound
hydrogen
use according
enhancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2008552415A
Other languages
English (en)
Japanese (ja)
Other versions
JP2009524675A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2007/002081 external-priority patent/WO2007087416A2/en
Publication of JP2009524675A publication Critical patent/JP2009524675A/ja
Publication of JP2009524675A5 publication Critical patent/JP2009524675A5/ja
Pending legal-status Critical Current

Links

JP2008552415A 2006-01-24 2007-01-24 テトラサイクリンの経口バイオアベイラビリティーを増加する方法 Pending JP2009524675A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US76181906P 2006-01-24 2006-01-24
PCT/US2007/002081 WO2007087416A2 (en) 2006-01-24 2007-01-24 Methods of increasing oral bioavailability of tetracyclines

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2010013625A Division JP2010106043A (ja) 2006-01-24 2010-01-25 テトラサイクリンの経口バイオアベイラビリティーを増加する方法

Publications (2)

Publication Number Publication Date
JP2009524675A JP2009524675A (ja) 2009-07-02
JP2009524675A5 true JP2009524675A5 (enExample) 2010-03-18

Family

ID=38181071

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2008552415A Pending JP2009524675A (ja) 2006-01-24 2007-01-24 テトラサイクリンの経口バイオアベイラビリティーを増加する方法
JP2010013625A Pending JP2010106043A (ja) 2006-01-24 2010-01-25 テトラサイクリンの経口バイオアベイラビリティーを増加する方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2010013625A Pending JP2010106043A (ja) 2006-01-24 2010-01-25 テトラサイクリンの経口バイオアベイラビリティーを増加する方法

Country Status (6)

Country Link
US (2) US9078811B2 (enExample)
EP (2) EP2298324A1 (enExample)
JP (2) JP2009524675A (enExample)
AU (2) AU2007208214B2 (enExample)
CA (1) CA2639406A1 (enExample)
WO (1) WO2007087416A2 (enExample)

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US7094806B2 (en) 2000-07-07 2006-08-22 Trustees Of Tufts College 7, 8 and 9-substituted tetracycline compounds
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EP1648859B1 (en) 2003-07-09 2013-02-27 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
US20060287283A1 (en) * 2003-07-09 2006-12-21 Paratek Pharmaceuticals, Inc. Prodrugs of 9-aminomethyl tetracycline compounds
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CN101128206A (zh) * 2005-01-21 2008-02-20 沃纳奇尔科特公司 固体剂型形式的四环素类金属络合物
WO2006084265A1 (en) * 2005-02-04 2006-08-10 Paratek Pharmaceuticals, Inc. 11a, 12-DERIVATIVES OF TETRACYCLINE COMPOUNDS
JP2009502809A (ja) * 2005-07-21 2009-01-29 パラテック ファーマシューティカルズ インコーポレイテッド １０−置換テトラサイクリンおよびその使用方法
CA2652347A1 (en) * 2006-05-15 2007-11-22 Paratek Pharmaceuticals, Inc. Methods of regulating expression of genes or of gene products using substituted tetracycline compounds
EP2450347B1 (en) 2006-12-21 2015-06-24 Paratek Pharmaceuticals, Inc. Tetracycline derivatives for the treatment of bacterial, viral and parasitic infections
PT2120963T (pt) 2006-12-21 2018-12-17 Paratek Pharm Innc Compostos tetraciclina substituídos para tratamento de distúrbios inflamatórios da pele
WO2008127722A1 (en) 2007-04-12 2008-10-23 Paratek Pharmaceuticals, Inc. Methods for treating spinal muscular atrophy using tetracycline compounds
US20090253660A1 (en) 2008-03-05 2009-10-08 Paratek Pharmaceuticals, Inc. Minocycline Compounds and Methods of Use Thereof
PT2271348T (pt) * 2008-03-28 2018-04-16 Paratek Pharm Innc Formulação de comprimido oral de composto de tetraciclina
JP2011517697A (ja) * 2008-04-14 2011-06-16 パラテック ファーマシューティカルズ インコーポレイテッド 置換テトラサイクリン化合物
TWI680117B (zh) * 2008-05-19 2019-12-21 派洛泰克藥物股份有限公司 四環素化合物之甲苯磺酸鹽及同素異形體
ES2558512T3 (es) 2008-08-08 2016-02-04 Tetraphase Pharmaceuticals, Inc. Compuestos de tetraciclina sustituida con C7-fluoro
US20100190755A1 (en) * 2008-09-19 2010-07-29 Paul Abato Tetracycline compounds for the treatment of rheumatoid arthritis and related methods of treatment
WO2010129057A2 (en) 2009-05-08 2010-11-11 Tetraphase Pharmaceuticals, Inc. Tetracycline compounds
HUE037852T2 (hu) 2009-08-28 2018-09-28 Tetraphase Pharmaceuticals Inc Tetraciklin-vegyületek
US9119793B1 (en) 2011-06-28 2015-09-01 Medicis Pharmaceutical Corporation Gastroretentive dosage forms for doxycycline
WO2013088255A1 (en) * 2011-12-15 2013-06-20 Alkermes Pharma Ireland Limited Prodrugs of secondary amine compounds
SMT201900096T1 (it) 2012-08-31 2019-02-28 Tetraphase Pharmaceuticals Inc Composti di tetracicline
US10842802B2 (en) 2013-03-15 2020-11-24 Medicis Pharmaceutical Corporation Controlled release pharmaceutical dosage forms
MX2018011413A (es) * 2016-03-24 2019-01-10 Paratek Pharm Innc Metodos para tratar y prevenir infeccion por c. difficile.
MA46567A (fr) 2016-10-19 2019-08-28 Tetraphase Pharmaceuticals Inc Formes cristallines de l'éravacycline
SG10201913599RA (en) 2016-11-01 2020-02-27 Paratek Pharm Innc 9-aminomethyl minocycline compounds and use thereof in treating community-acquired bacterial pneumonia (cabp)
PT117254B (pt) 2021-05-26 2024-04-18 Hovione Farm S A Método de síntese de compostos 9-aminometil tetraciclinas
WO2023238143A1 (en) * 2022-06-11 2023-12-14 Gufic Biosciences Limited A freeze dried parenteral composition of omadacycline tosylate with improved stability

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SI1301467T1 (sl) * 2000-07-07 2007-02-28 Tufts College 9-substituirane minociklinske spojine
KR100863146B1 (ko) * 2000-07-17 2008-10-14 아스텔라스세이야쿠 가부시키가이샤 경구 흡수 개선 의약 조성물
EP1368305B1 (en) 2001-03-13 2008-08-13 Paratek Pharmaceuticals, Inc. 7, 9-substituted tetracycline compounds
WO2002072031A2 (en) 2001-03-14 2002-09-19 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds as synergistic antifungal agents
ITMI20011756A1 (it) 2001-08-09 2003-02-09 Remedia S R L Composizione farmaceutica comprendente una microemulsione doppia acqua/olio/acqua incorporata in un supporto solido
ES2551708T3 (es) 2002-01-08 2015-11-23 Paratek Pharmaceuticals, Inc. Compuestos de 4-desdimetilamino tetraciclina
WO2003079984A2 (en) 2002-03-21 2003-10-02 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
CA2503446C (en) * 2002-10-24 2012-12-18 Paratek Pharmaceuticals, Inc. Methods of using substituted tetracycline compounds to modulate rna
US6841547B2 (en) * 2003-02-28 2005-01-11 Albert Einstein College Of Medicine Of Yeshevia University Method for decreasing low density lipoprotein
WO2004091513A2 (en) * 2003-04-10 2004-10-28 Paratek Pharmaceuticals, Inc. 9-aminomethyl substituted minocycline compounds
JP4738333B2 (ja) 2003-07-09 2011-08-03 パラテック ファーマシューティカルズ インコーポレイテッド ９−アミノメチルテトラサイクリン化合物のプロドラッグ
EP1648859B1 (en) 2003-07-09 2013-02-27 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
WO2005016311A1 (en) * 2003-08-11 2005-02-24 Advancis Pharmaceutical Corporation Robust pellet
WO2005046651A1 (en) 2003-11-12 2005-05-26 Ranbaxy Laboratories Limited Liquid filled capsules of doxycycline
GB2414668B (en) * 2004-06-03 2009-07-29 Dexcel Ltd Tetracycline modified release delivery system

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