JP2009523411A5 - - Google Patents

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Publication number
JP2009523411A5
JP2009523411A5 JP2008545095A JP2008545095A JP2009523411A5 JP 2009523411 A5 JP2009523411 A5 JP 2009523411A5 JP 2008545095 A JP2008545095 A JP 2008545095A JP 2008545095 A JP2008545095 A JP 2008545095A JP 2009523411 A5 JP2009523411 A5 JP 2009523411A5
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JP
Japan
Prior art keywords
flg
mutation
repeat
gene
filaggrin
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JP2008545095A
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English (en)
Japanese (ja)
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JP5305921B2 (ja
JP2009523411A (ja
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Priority claimed from GBGB0525492.5A external-priority patent/GB0525492D0/en
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Publication of JP2009523411A publication Critical patent/JP2009523411A/ja
Publication of JP2009523411A5 publication Critical patent/JP2009523411A5/ja
Application granted granted Critical
Publication of JP5305921B2 publication Critical patent/JP5305921B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2008545095A 2005-12-15 2006-12-15 フィラグリン Expired - Fee Related JP5305921B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0525492.5A GB0525492D0 (en) 2005-12-15 2005-12-15 Filaggrin
GB0525492.5 2005-12-15
PCT/GB2006/004707 WO2007068946A2 (en) 2005-12-15 2006-12-15 Identification of loss-of-function mutations in filaggrin causing ichthyosis vulgaris and predisposing to other diseases

Publications (3)

Publication Number Publication Date
JP2009523411A JP2009523411A (ja) 2009-06-25
JP2009523411A5 true JP2009523411A5 (https=) 2010-02-12
JP5305921B2 JP5305921B2 (ja) 2013-10-02

Family

ID=35736147

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008545095A Expired - Fee Related JP5305921B2 (ja) 2005-12-15 2006-12-15 フィラグリン

Country Status (5)

Country Link
US (1) US8999635B2 (https=)
EP (1) EP1960539B1 (https=)
JP (1) JP5305921B2 (https=)
GB (2) GB0525492D0 (https=)
WO (1) WO2007068946A2 (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0600948D0 (en) 2006-01-18 2006-02-22 Univ Dundee Prevention/Treatment Of Ichthyosis Vulgaris, Atopy And Other Disorders
WO2009002170A1 (en) * 2007-06-28 2008-12-31 Erasmus University Medical Center Rotterdam Method for determination of a potential mutation
EP2322656A1 (en) * 2009-11-17 2011-05-18 Centre National de la Recherche Scientifique (C.N.R.S) Methods for diagnosing skin diseases
AU2010321784B2 (en) 2009-11-23 2014-04-24 Research Development Foundation Recombinant filaggrin polypeptides for cell importation
JP5771123B2 (ja) * 2011-11-09 2015-08-26 株式会社 資生堂 プロフィラグリンｃ末端ドメイン特異的抗体及びその用途
GB201222881D0 (en) * 2012-12-19 2013-01-30 Univ Dundee Animal model
JP5943945B2 (ja) * 2014-01-29 2016-07-05 株式会社 資生堂 プロフィラグリンｃ末端ドメイン特異的抗体及びその用途
JP6803113B2 (ja) * 2016-07-01 2020-12-23 共栄化学工業株式会社 評価方法及び皮膚外用剤
RU2673804C1 (ru) * 2018-01-25 2018-11-30 ФЕДЕРАЛЬНОЕ ГОСУДАРСТВЕННОЕ БЮДЖЕТНОЕ НАУЧНОЕ УЧРЕЖДЕНИЕ "ФЕДЕРАЛЬНЫЙ ИССЛЕДОВАТЕЛЬСКИЙ ЦЕНТР ИНСТИТУТ ЦИТОЛОГИИ И ГЕНЕТИКИ СИБИРСКОГО ОТДЕЛЕНИЯ РОССИЙСКОЙ АКАДЕМИИ НАУК" (ИЦиГ СО РАН) Способ выявления мутаций 2282del4, R501X, R2447X в гене филаггрина (FLG) при вульгарном ихтиозе и атопическом дерматите
WO2019195714A1 (en) 2018-04-05 2019-10-10 Azitra Inc Methods and compositions for treating skin disease with recombinant microorganisms
WO2020076770A1 (en) * 2018-10-08 2020-04-16 Yale University Selective binding and aggregation of human keratin in the skin barrier using human filaggrin subdomains sd67 and sd150
CN113092768A (zh) * 2019-12-23 2021-07-09 首都医科大学附属北京世纪坛医院 尿液角蛋白,ii型细胞骨架1及其多肽片段在过敏性疾病中的应用
CN116874576B (zh) * 2023-06-28 2024-03-12 胡荣洋 一种重组人源化丝聚蛋白及其制备方法和应用
CN118460707B (zh) * 2024-07-15 2024-09-17 山东大学 检测寻常鱼鳞病相关flg基因突变的引物组、试剂盒及方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ20001963A3 (cs) * 1997-11-28 2002-04-17 Innogenetics N. V. Peptidy obsahující citrulin rozeznaný sérem revmatické artritidy jako prostředky pro diagnózu a léčbu
US6143502A (en) 1999-03-31 2000-11-07 University Of Utah Research Foundation Dual-luciferase reporter system
US6458538B1 (en) 1999-12-14 2002-10-01 Ptc Therapeutics, Inc. Methods of assaying for compounds that inhibit premature translation termination and nonsense-mediated RNA decay
GB0111324D0 (en) * 2001-05-09 2001-07-04 Unilever Plc Ambient stable beverage
IL159311A0 (en) 2001-06-13 2004-06-01 Remedies for diseases caused by nonsense mutation
US7927791B2 (en) 2002-07-24 2011-04-19 Ptc Therapeutics, Inc. Methods for identifying small molecules that modulate premature translation termination and nonsense mediated mRNA decay
FI20031927A0 (fi) 2003-12-31 2003-12-31 Faron Pharmaceuticals Oy Terapeuttisesti vaikuttavia aineita ja niiden käyttö
GB0600948D0 (en) 2006-01-18 2006-02-22 Univ Dundee Prevention/Treatment Of Ichthyosis Vulgaris, Atopy And Other Disorders

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