JP2009520692A - 改良されたジャスモネート誘導体、医薬組成物及びそれらの使用方法 - Google Patents

改良されたジャスモネート誘導体、医薬組成物及びそれらの使用方法 Download PDF

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JP2009520692A
JP2009520692A JP2008544003A JP2008544003A JP2009520692A JP 2009520692 A JP2009520692 A JP 2009520692A JP 2008544003 A JP2008544003 A JP 2008544003A JP 2008544003 A JP2008544003 A JP 2008544003A JP 2009520692 A JP2009520692 A JP 2009520692A
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cancer
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leukemia
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JP2009520692A5 (enExample
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ハーツバーグ、マックス
ハレル、エイドリアン
マング、クリスチャン
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セパル ファーマ リミテッド
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
JP2008544003A 2005-12-07 2006-12-07 改良されたジャスモネート誘導体、医薬組成物及びそれらの使用方法 Pending JP2009520692A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US74287505P 2005-12-07 2005-12-07
US77258206P 2006-02-13 2006-02-13
US83066606P 2006-07-14 2006-07-14
PCT/IL2006/001409 WO2007066337A2 (en) 2005-12-07 2006-12-07 Jasmonate derivatives, pharmaceutical compositions and methods of use thereof

Publications (2)

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JP2009520692A true JP2009520692A (ja) 2009-05-28
JP2009520692A5 JP2009520692A5 (enExample) 2010-01-28

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Family Applications (1)

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JP2008544003A Pending JP2009520692A (ja) 2005-12-07 2006-12-07 改良されたジャスモネート誘導体、医薬組成物及びそれらの使用方法

Country Status (7)

Country Link
US (1) US8247439B2 (enExample)
EP (1) EP1968959A2 (enExample)
JP (1) JP2009520692A (enExample)
AU (1) AU2006322845A1 (enExample)
BR (1) BRPI0619551A2 (enExample)
CA (1) CA2630666A1 (enExample)
WO (1) WO2007066337A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018502855A (ja) * 2014-12-31 2018-02-01 ナノケア テクノロジーズ，インコーポレイティド ジャスモネート誘導体及びそれらの組成物

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9284274B2 (en) 2005-12-07 2016-03-15 Ramot At Tel-Aviv University Ltd. Chemical derivatives of jasmonate, pharmaceutical compositions and methods of use thereof
CN101511351A (zh) * 2006-07-10 2009-08-19 雷蒙特亚特特拉维夫大学有限公司 治疗癌症的组合方法
JP2010521149A (ja) 2007-03-15 2010-06-24 ラモット アット テル−アヴィヴ ユニヴァーシティ リミテッド ミトコンドリア結合ヘキソキナーゼを選択的に阻害する化合物の同定のためのジャスモン酸エステルに基づくアッセイ
WO2009120826A1 (en) * 2008-03-27 2009-10-01 Wyeth 2-aryl- and 2-heteroarylthiazolyl compounds, methods for their preparation and use thereof
US9284252B2 (en) 2009-06-09 2016-03-15 Sepal Pharma Ltd. Use of jasmonate ester derivatives for treating benign hyperproliferative skin disorders
AU2012221877A1 (en) 2011-02-25 2013-09-19 Nanocare Technologies, Inc. Pharmaceutical formulation comprising compounds of the jasmonate family
US8883220B2 (en) 2011-09-16 2014-11-11 Nanocare Technologies, Inc. Compositions of jasmonate compounds
US20200297620A1 (en) 2016-03-28 2020-09-24 Vidac Pharma Ltd Stable pharmaceutical compositions for topical administration and uses thereof
WO2018083704A1 (en) 2016-11-07 2018-05-11 Vidac Pharma Ltd. Use of hexokinase 2/mitochondria-detaching compounds for activating immune responses
WO2018083705A1 (en) 2016-11-07 2018-05-11 Vidac Pharma Ltd. Use of hexokinase 2/mitochondria-detaching compounds for treating hexokinase-2 (hk2)-expressing cancers
WO2019135243A1 (en) * 2018-01-07 2019-07-11 Vidac Pharma Ltd Methods for preparation of jasmonate compounds

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63122669A (ja) * 1986-10-25 1988-05-26 メルク・パテント・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング 複素環状液晶化合物
JPH07308196A (ja) * 1994-05-18 1995-11-28 Mitsui Petrochem Ind Ltd タキサン型ジテルペンの製造方法
WO2004063155A1 (en) * 2003-01-06 2004-07-29 Eli Lilly And Company Fused heterocyclic derivatives as ppar modulators
JP2004525163A (ja) * 2001-04-04 2004-08-19 ラモット アット テル アヴィヴ ユニヴァーシティ リミテッド 癌治療のためのジャスモネート医薬組成物
WO2005054172A2 (en) * 2003-12-02 2005-06-16 Ramot At Tel-Aviv University Ltd. Jasmonate derivative compounds, pharmaceuticals compositions and methods of use thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5476945A (en) * 1992-11-17 1995-12-19 Fuji Photo Film Co., Ltd. Water-soluble methine derivatives of thiazole
EP1348764A1 (en) * 1993-11-15 2003-10-01 Mitsui Chemicals, Inc. A Method of Producing a Taxane-Type Diterpene and Method of Obtaining Cultured Cells which Produce the Taxane-Type Diterpene at a High Rate
AU2002254342A1 (en) * 2001-03-23 2002-10-08 The Board Of Trustees Of The University Of Illinois Compounds capable of modulating the activity of multidrug transporters and therapeutic use of the same
FR2825926A1 (fr) * 2001-06-14 2002-12-20 Sod Conseils Rech Applic Derives d'imidazoles modulant les canaux sodiques

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63122669A (ja) * 1986-10-25 1988-05-26 メルク・パテント・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング 複素環状液晶化合物
JPH07308196A (ja) * 1994-05-18 1995-11-28 Mitsui Petrochem Ind Ltd タキサン型ジテルペンの製造方法
JP2004525163A (ja) * 2001-04-04 2004-08-19 ラモット アット テル アヴィヴ ユニヴァーシティ リミテッド 癌治療のためのジャスモネート医薬組成物
WO2004063155A1 (en) * 2003-01-06 2004-07-29 Eli Lilly And Company Fused heterocyclic derivatives as ppar modulators
WO2005054172A2 (en) * 2003-12-02 2005-06-16 Ramot At Tel-Aviv University Ltd. Jasmonate derivative compounds, pharmaceuticals compositions and methods of use thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018502855A (ja) * 2014-12-31 2018-02-01 ナノケア テクノロジーズ，インコーポレイティド ジャスモネート誘導体及びそれらの組成物

Also Published As

Publication number Publication date
EP1968959A2 (en) 2008-09-17
US8247439B2 (en) 2012-08-21
BRPI0619551A2 (pt) 2011-10-04
AU2006322845A1 (en) 2007-06-14
WO2007066337A2 (en) 2007-06-14
US20090197927A1 (en) 2009-08-06
CA2630666A1 (en) 2007-06-14
WO2007066337A3 (en) 2007-11-15

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