JP2009520682A5 - - Google Patents

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Publication number
JP2009520682A5
JP2009520682A5 JP2008529406A JP2008529406A JP2009520682A5 JP 2009520682 A5 JP2009520682 A5 JP 2009520682A5 JP 2008529406 A JP2008529406 A JP 2008529406A JP 2008529406 A JP2008529406 A JP 2008529406A JP 2009520682 A5 JP2009520682 A5 JP 2009520682A5
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JP
Japan
Prior art keywords
tyr
compound
azagly
asn
trp
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2008529406A
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English (en)
Japanese (ja)
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JP4653840B2 (ja
JP2009520682A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/JP2006/326176 external-priority patent/WO2007072997A1/en
Publication of JP2009520682A publication Critical patent/JP2009520682A/ja
Publication of JP2009520682A5 publication Critical patent/JP2009520682A5/ja
Application granted granted Critical
Publication of JP4653840B2 publication Critical patent/JP4653840B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2008529406A 2005-12-22 2006-12-21 メタスチン誘導体およびその用途 Expired - Fee Related JP4653840B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2005370388 2005-12-22
JP2006275843 2006-10-06
PCT/JP2006/326176 WO2007072997A1 (en) 2005-12-22 2006-12-21 Metastin derivatives and use thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2010182482A Division JP5298087B2 (ja) 2005-12-22 2010-08-17 メタスチン誘導体およびその用途

Publications (3)

Publication Number Publication Date
JP2009520682A JP2009520682A (ja) 2009-05-28
JP2009520682A5 true JP2009520682A5 (enExample) 2010-10-07
JP4653840B2 JP4653840B2 (ja) 2011-03-16

Family

ID=37846230

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2008529406A Expired - Fee Related JP4653840B2 (ja) 2005-12-22 2006-12-21 メタスチン誘導体およびその用途
JP2010182482A Active JP5298087B2 (ja) 2005-12-22 2010-08-17 メタスチン誘導体およびその用途

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2010182482A Active JP5298087B2 (ja) 2005-12-22 2010-08-17 メタスチン誘導体およびその用途

Country Status (29)

Country Link
US (1) US7960348B2 (enExample)
EP (1) EP1963362B1 (enExample)
JP (2) JP4653840B2 (enExample)
KR (1) KR101368607B1 (enExample)
AR (1) AR058584A1 (enExample)
AU (1) AU2006328333B2 (enExample)
BR (1) BRPI0619399B8 (enExample)
CA (1) CA2634647C (enExample)
CR (1) CR10019A (enExample)
CY (1) CY1112353T1 (enExample)
DK (1) DK1963362T3 (enExample)
ES (1) ES2375038T3 (enExample)
GE (1) GEP20115356B (enExample)
HR (1) HRP20110851T1 (enExample)
IL (1) IL190888A (enExample)
JO (1) JO2799B1 (enExample)
MA (1) MA30060B1 (enExample)
ME (1) ME01015B (enExample)
MY (1) MY151967A (enExample)
NO (1) NO341879B1 (enExample)
NZ (1) NZ568322A (enExample)
PE (1) PE20071141A1 (enExample)
PL (1) PL1963362T3 (enExample)
PT (1) PT1963362E (enExample)
RS (1) RS52007B (enExample)
RU (1) RU2430107C2 (enExample)
SI (1) SI1963362T1 (enExample)
TW (1) TWI386417B (enExample)
WO (1) WO2007072997A1 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2511858A1 (en) 2002-12-26 2004-07-29 Takeda Pharmaceutical Company Limited Metastin derivative and use thereof
US7754220B2 (en) 2003-03-12 2010-07-13 Takeda Pharmaceutical Company Limited Methods of inhibiting secretion of follicle-stimulating hormone and testosterone
US7625869B2 (en) 2004-06-25 2009-12-01 Takeda Pharmaceutical Company Limited Metastin derivatives and use thereof
US20090093615A1 (en) * 2005-12-22 2009-04-09 Takeda Pharmaceutical Company Limited Metastin derivatives and use thereof
AR058584A1 (es) 2005-12-22 2008-02-13 Takeda Pharmaceutical Derivados de metastina y uso de los mismos
US8404643B2 (en) 2005-12-22 2013-03-26 Takeda Pharmaceutical Company Limited Metastin derivatives and use thereof
JO3048B1 (ar) 2006-10-25 2016-09-05 Takeda Pharmaceuticals Co مشتقات متاستين واستخدامها
EP2277900A4 (en) * 2008-04-24 2011-08-03 Takeda Pharmaceutical METASTINE DERIVATIVE AND ITS USE
WO2010013762A1 (ja) 2008-07-30 2010-02-04 武田薬品工業株式会社 メタスチン誘導体およびその用途
PE20110939A1 (es) * 2008-12-29 2012-01-19 Takeda Pharmaceutical Agente preventivo/terapeutico contra el cancer
MA33910B1 (fr) * 2009-12-22 2013-01-02 Takeda Pharmaceutcal Company Ltd Formulation à libération prolongée
TW201204378A (en) * 2010-06-25 2012-02-01 Takeda Pharmaceutical Sustained-release formulation
EP2755690B1 (en) 2011-08-04 2020-04-01 Merck Sharp & Dohme B.V. Kisspeptide-pentasaccharide conjugates
EP2873455B1 (en) 2012-07-12 2021-07-07 Takeda Pharmaceutical Company Limited Method for manufacturing microcapsule powder
WO2015112703A1 (en) * 2014-01-22 2015-07-30 The Johns Hopkins University Compositions and methods for treating diabetes
JP6253146B2 (ja) * 2014-02-04 2017-12-27 国立大学法人山口大学 新規なペプチド誘導体及びこれを含有する医薬
MA46353A (fr) 2016-09-30 2019-08-07 Myovant Sciences Gmbh Méthodes de traitement de l'infertilité féminine
SI3518933T2 (sl) 2016-09-30 2025-05-30 Sumitomo Pharma Switzerland Gmbh Metode zdravljenja materničnih miom in endometrioze
US11427615B2 (en) 2017-07-05 2022-08-30 Xdcexplorer (Shanghai) Co., Ltd. Peptide compound and application thereof, and composition containing peptide compound
WO2025217074A1 (en) 2024-04-08 2025-10-16 Radionetics Oncology, Inc. Kisspeptin receptor (kiss1r) targeted therapeutics and uses thereof

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MX9100717A (es) 1990-08-24 1992-04-01 Syntex Inc Antagonistas de la bradiquinina
DE69623655T2 (de) 1995-10-19 2003-04-24 Takeda Chemical Industries, Ltd. Chinolinderivate als gnrh antagonisten
JPH09169735A (ja) 1995-10-19 1997-06-30 Takeda Chem Ind Ltd キノリン誘導体、その製造法および用途
WO1997040071A1 (en) 1996-04-19 1997-10-30 Novo Nordisk A/S Compounds with growth hormone releasing properties
CA2283299A1 (en) 1997-03-07 1998-09-11 Human Genome Sciences, Inc. 186 human secreted proteins
JP4486187B2 (ja) 1998-10-27 2010-06-23 武田薬品工業株式会社 新規ｇ蛋白質共役型レセプター蛋白質、そのｄｎａおよびそのリガンド
US6528054B1 (en) 1998-12-28 2003-03-04 Corixa Corporation Compositions and methods for the therapy and diagnosis of breast cancer
MXPA01013367A (es) 1999-06-28 2002-07-02 Basf Ag Metodo para la prevencion del crecimiento tumoral.
DE60042552D1 (de) 1999-08-02 2009-08-27 Archer Daniels Midland Co Metabolische manipulation der produktion von aminosäuren
US6838259B2 (en) * 1999-12-17 2005-01-04 Takeda Chemical Industries, Ltd. Process for producing kiss-1 peptide
CA2404233A1 (en) 2000-03-29 2001-10-04 Corixa Corporation Compositions and methods for the therapy and diagnosis of lung cancer
EP1273658A4 (en) 2000-03-30 2004-08-11 Takeda Chemical Industries Ltd NEW PROTEIN, THEIR DNA AND METHOD FOR THE PRODUCTION THEREOF
US7834141B1 (en) 2000-03-31 2010-11-16 Theresa Siler-Khodr Non-mammalian GnRH analogs and uses thereof in tumor cell growth regulation and cancer therapy
RU2311920C2 (ru) 2000-09-20 2007-12-10 Корикса Корпорейшн Композиции и способы для лечения и диагностики рака легких
JP2003026601A (ja) 2000-11-29 2003-01-29 Takeda Chem Ind Ltd 医薬組成物およびその製造法
JP2002320496A (ja) 2001-02-26 2002-11-05 Takeda Chem Ind Ltd 新規マウス型ＫｉＳＳ−１レセプタータンパク質およびそのＤＮＡ
WO2002085399A1 (fr) 2001-04-20 2002-10-31 Takeda Chemical Industries, Ltd. Preparations contenant un peptide
US20040185525A1 (en) * 2001-05-17 2004-09-23 Osamu Nishimura Process for producing peptide
EP1428835B1 (en) * 2001-09-19 2007-04-18 Takeda Pharmaceutical Company Limited Antibody against metastin and use of the same in the diagnosis of pregnancy
EP1466976A4 (en) 2002-01-11 2005-11-09 Takeda Pharmaceutical PROCESS FOR PREPARING KISS-1 PEPTIDES
JP2003300906A (ja) 2002-04-12 2003-10-21 Daiichi Fine Chemical Co Ltd がん転移抑制因子の安定化
WO2004038021A1 (en) 2002-10-25 2004-05-06 Paradigm Therapeutics Limited Gpr54 knock-out mammals and screening methods using them
CA2511858A1 (en) * 2002-12-26 2004-07-29 Takeda Pharmaceutical Company Limited Metastin derivative and use thereof
JP4804714B2 (ja) * 2002-12-26 2011-11-02 武田薬品工業株式会社 メタスチン誘導体およびその用途
US6800611B2 (en) * 2003-01-06 2004-10-05 Takeda Chemical Industries, Ltd. Metastin derivatives and their use
KR100595364B1 (ko) 2003-02-20 2006-07-03 재단법인 목암생명공학연구소 Ｌｋ8 단백질을 유효성분으로 포함하는 항암제
US7754220B2 (en) * 2003-03-12 2010-07-13 Takeda Pharmaceutical Company Limited Methods of inhibiting secretion of follicle-stimulating hormone and testosterone
EP1464652A1 (en) 2003-04-02 2004-10-06 Institut National De La Sante Et De La Recherche Medicale (Inserm) GPR54 receptor agonist and antagonist useful for the treatment of gonadotropin related diseases
US20050002935A1 (en) 2003-04-17 2005-01-06 Vincent Ling Use of B7-H3 as an immunoregulatory agent
US20050026224A1 (en) 2003-04-28 2005-02-03 Follettie Maximillian T. Methods and compositions for modulating G-protein coupled receptor 54
WO2004101747A2 (en) 2003-05-07 2004-11-25 The General Hospital Corporation Identification and use of gpr54 and its ligands for reproductive disorders and contraception
WO2004106289A1 (en) * 2003-05-30 2004-12-09 Prozymex A/S Protease inhibitors
BRPI0318594B8 (pt) 2003-11-03 2021-05-25 Beijing Sunbio Biotech Co Ltd proteína recombinante que possui um efeito anticâncer, seu gene de codificação, seu uso, medicamento para tratar cânceres, vetor de expressão e microrganismo transgênico
RU2333221C2 (ru) 2003-11-03 2008-09-10 Бейцзин Санбио Байотек Ко., Лтд. Рекомбинантный белок, обладающий противораковым действием, кодирующий его ген и его применение
WO2005095973A2 (en) 2004-03-25 2005-10-13 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with g-protein coupled receptor 54 (gpr54)
US7625869B2 (en) * 2004-06-25 2009-12-01 Takeda Pharmaceutical Company Limited Metastin derivatives and use thereof
US7725869B1 (en) * 2005-04-07 2010-05-25 Xilinx, Inc. Method and apparatus for modeling multiple instances of an electronic circuit using an imperative programming language description
WO2007084211A2 (en) 2005-11-11 2007-07-26 The General Hospital Corporation Use of gpr54 ligands for treatment of reproductive disorders, proliferative disorders, and for contraception
US8404643B2 (en) * 2005-12-22 2013-03-26 Takeda Pharmaceutical Company Limited Metastin derivatives and use thereof
AR058584A1 (es) 2005-12-22 2008-02-13 Takeda Pharmaceutical Derivados de metastina y uso de los mismos
US20090093615A1 (en) * 2005-12-22 2009-04-09 Takeda Pharmaceutical Company Limited Metastin derivatives and use thereof
US20090099334A1 (en) * 2005-12-22 2009-04-16 Takeda Pharmaceutical Company Limited Metastin derivatives and use thereof
JO3048B1 (ar) 2006-10-25 2016-09-05 Takeda Pharmaceuticals Co مشتقات متاستين واستخدامها

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