JP2009520682A5 - - Google Patents

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Publication number
JP2009520682A5
JP2009520682A5 JP2008529406A JP2008529406A JP2009520682A5 JP 2009520682 A5 JP2009520682 A5 JP 2009520682A5 JP 2008529406 A JP2008529406 A JP 2008529406A JP 2008529406 A JP2008529406 A JP 2008529406A JP 2009520682 A5 JP2009520682 A5 JP 2009520682A5
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JP
Japan
Prior art keywords
tyr
compound
azagly
asn
trp
Prior art date
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JP2008529406A
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English (en)
Japanese (ja)
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JP2009520682A (ja
JP4653840B2 (ja
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Publication date
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Priority claimed from PCT/JP2006/326176 external-priority patent/WO2007072997A1/en
Publication of JP2009520682A publication Critical patent/JP2009520682A/ja
Publication of JP2009520682A5 publication Critical patent/JP2009520682A5/ja
Application granted granted Critical
Publication of JP4653840B2 publication Critical patent/JP4653840B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2008529406A 2005-12-22 2006-12-21 メタスチン誘導体およびその用途 Expired - Fee Related JP4653840B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2005370388 2005-12-22
JP2006275843 2006-10-06
PCT/JP2006/326176 WO2007072997A1 (en) 2005-12-22 2006-12-21 Metastin derivatives and use thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2010182482A Division JP5298087B2 (ja) 2005-12-22 2010-08-17 メタスチン誘導体およびその用途

Publications (3)

Publication Number Publication Date
JP2009520682A JP2009520682A (ja) 2009-05-28
JP2009520682A5 true JP2009520682A5 (enExample) 2010-10-07
JP4653840B2 JP4653840B2 (ja) 2011-03-16

Family

ID=37846230

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2008529406A Expired - Fee Related JP4653840B2 (ja) 2005-12-22 2006-12-21 メタスチン誘導体およびその用途
JP2010182482A Expired - Fee Related JP5298087B2 (ja) 2005-12-22 2010-08-17 メタスチン誘導体およびその用途

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2010182482A Expired - Fee Related JP5298087B2 (ja) 2005-12-22 2010-08-17 メタスチン誘導体およびその用途

Country Status (29)

Country Link
US (1) US7960348B2 (enExample)
EP (1) EP1963362B1 (enExample)
JP (2) JP4653840B2 (enExample)
KR (1) KR101368607B1 (enExample)
AR (1) AR058584A1 (enExample)
AU (1) AU2006328333B2 (enExample)
BR (1) BRPI0619399B8 (enExample)
CA (1) CA2634647C (enExample)
CR (1) CR10019A (enExample)
CY (1) CY1112353T1 (enExample)
DK (1) DK1963362T3 (enExample)
ES (1) ES2375038T3 (enExample)
GE (1) GEP20115356B (enExample)
HR (1) HRP20110851T1 (enExample)
IL (1) IL190888A (enExample)
JO (1) JO2799B1 (enExample)
MA (1) MA30060B1 (enExample)
ME (1) ME01015B (enExample)
MY (1) MY151967A (enExample)
NO (1) NO341879B1 (enExample)
NZ (1) NZ568322A (enExample)
PE (1) PE20071141A1 (enExample)
PL (1) PL1963362T3 (enExample)
PT (1) PT1963362E (enExample)
RS (1) RS52007B (enExample)
RU (1) RU2430107C2 (enExample)
SI (1) SI1963362T1 (enExample)
TW (1) TWI386417B (enExample)
WO (1) WO2007072997A1 (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003292696A1 (en) 2002-12-26 2004-08-10 Takeda Pharmaceutical Company Limited Metastin derivative and use thereof
EP1604682A4 (en) 2003-03-12 2009-06-24 Takeda Chemical Industries Ltd AGENTS IMPROVING GONADIC FUNCTION
MXPA06014206A (es) 2004-06-25 2007-02-14 Takeda Pharmaceutical Derivados de metastina y uso de los mismos.
TWI386417B (zh) 2005-12-22 2013-02-21 Takeda Pharmaceutical 轉移抑素衍生物及其用途
US8404643B2 (en) 2005-12-22 2013-03-26 Takeda Pharmaceutical Company Limited Metastin derivatives and use thereof
US20090093615A1 (en) * 2005-12-22 2009-04-09 Takeda Pharmaceutical Company Limited Metastin derivatives and use thereof
TWI404726B (zh) 2006-10-25 2013-08-11 Takeda Pharmaceutical 腫瘤轉移抑制素衍生物及其用途
EP2277900A4 (en) * 2008-04-24 2011-08-03 Takeda Pharmaceutical METASTINE DERIVATIVE AND ITS USE
US20110212890A1 (en) * 2008-07-30 2011-09-01 Takeda Pharmaceutical Company Limited Metastin derivative and use thereof
CA2748517A1 (en) * 2008-12-29 2010-07-08 Takeda Pharmaceutical Company Limited Prophylactic/therapeutic agent for cancer
UY33127A (es) * 2009-12-22 2011-07-29 Takeda Pharmaceutical Formulación de liberación sostenida
BR112012032544A2 (pt) * 2010-06-25 2016-10-11 Takeda Pharmaceutical formulação de liberação prolongada, uso de um composto, e, método para produzir a formulação de liberação prolongada.
US9127038B2 (en) 2011-08-04 2015-09-08 Merck Sharp & Dohme Corp. Kisspeptide-pentasaccharide conjugates
WO2014010614A1 (ja) 2012-07-12 2014-01-16 武田薬品工業株式会社 マイクロカプセル粉末の製造方法
US10220069B2 (en) * 2014-01-22 2019-03-05 The Johns Hopkins University Compositions and methods for treating diabetes
JP6253146B2 (ja) * 2014-02-04 2017-12-27 国立大学法人山口大学 新規なペプチド誘導体及びこれを含有する医薬
MA46353A (fr) * 2016-09-30 2019-08-07 Myovant Sciences Gmbh Méthodes de traitement de l'infertilité féminine
ES2912929T5 (en) 2016-09-30 2025-05-09 Sumitomo Pharma Switzerland Gmbh Methods of treating uterine fibroids and endometriosis
CN109206481B (zh) * 2017-07-05 2023-08-18 尚华医药科技(江西)有限公司 一种肽类化合物、其应用及含其的组合物
CA3185151A1 (en) 2020-05-29 2021-12-02 Myovant Sciences Gmbh Combination solid oral dosage forms of gonadotropin-releasing hormone antagonists
WO2025217074A1 (en) * 2024-04-08 2025-10-16 Radionetics Oncology, Inc. Kisspeptin receptor (kiss1r) targeted therapeutics and uses thereof

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Publication number Priority date Publication date Assignee Title
IL74827A (en) 1984-05-21 1989-06-30 Salk Inst For Biological Studi Peptides active as gnrh antagonists and pharmaceutical compositions containing them
MX9100717A (es) 1990-08-24 1992-04-01 Syntex Inc Antagonistas de la bradiquinina
JPH09169735A (ja) 1995-10-19 1997-06-30 Takeda Chem Ind Ltd キノリン誘導体、その製造法および用途
AU7333496A (en) 1995-10-19 1997-05-07 Takeda Chemical Industries Ltd. Quinoline derivatives as gnrh antagonists
AU2382097A (en) 1996-04-19 1997-11-12 Novo Nordisk A/S Compounds with growth hormone releasing properties
CA2283299A1 (en) 1997-03-07 1998-09-11 Human Genome Sciences, Inc. 186 human secreted proteins
JP4486187B2 (ja) * 1998-10-27 2010-06-23 武田薬品工業株式会社 新規ｇ蛋白質共役型レセプター蛋白質、そのｄｎａおよびそのリガンド
US6528054B1 (en) 1998-12-28 2003-03-04 Corixa Corporation Compositions and methods for the therapy and diagnosis of breast cancer
HK1047045A1 (zh) 1999-06-28 2003-02-07 Abbott Gmbh & Co. Kg 預防腫瘤生長的方法
CA2380613C (en) 1999-08-02 2014-03-25 Archer-Daniels-Midland Company Production of l-lysine by corynebacterium strain having mutation in ilvbn operon
WO2001044469A1 (fr) 1999-12-17 2001-06-21 Takeda Chemical Industries, Ltd. PROCEDE DE PRODUCTION DE PEPTIDE KiSS-1
HUP0500345A2 (hu) 2000-03-29 2005-07-28 Corixa Corporation Készítmények és alkalmazások tüdőrák kezelésére és diagnosztizálására
CA2404257A1 (en) 2000-03-30 2001-10-11 Takeda Chemical Industries, Ltd. Novel protein, dna thereof and process for producing the same
US7834141B1 (en) 2000-03-31 2010-11-16 Theresa Siler-Khodr Non-mammalian GnRH analogs and uses thereof in tumor cell growth regulation and cancer therapy
RU2311920C2 (ru) 2000-09-20 2007-12-10 Корикса Корпорейшн Композиции и способы для лечения и диагностики рака легких
JP2003026601A (ja) 2000-11-29 2003-01-29 Takeda Chem Ind Ltd 医薬組成物およびその製造法
JP2002320496A (ja) 2001-02-26 2002-11-05 Takeda Chem Ind Ltd 新規マウス型ＫｉＳＳ−１レセプタータンパク質およびそのＤＮＡ
WO2002085399A1 (fr) 2001-04-20 2002-10-31 Takeda Chemical Industries, Ltd. Preparations contenant un peptide
US20040185525A1 (en) * 2001-05-17 2004-09-23 Osamu Nishimura Process for producing peptide
ATE360034T1 (de) * 2001-09-19 2007-05-15 Takeda Pharmaceutical Antikörper gegen metastin und dessen verwendung zur diagnose von schwangerschaft
EP1466976A4 (en) 2002-01-11 2005-11-09 Takeda Pharmaceutical PROCESS FOR PREPARING KISS-1 PEPTIDES
JP2003300906A (ja) 2002-04-12 2003-10-21 Daiichi Fine Chemical Co Ltd がん転移抑制因子の安定化
CA2503164A1 (en) 2002-10-25 2004-05-06 Paradigm Therapeutics Limited Gpr54 knock-out mammals and screening methods using them
AU2003292696A1 (en) * 2002-12-26 2004-08-10 Takeda Pharmaceutical Company Limited Metastin derivative and use thereof
JP4804714B2 (ja) * 2002-12-26 2011-11-02 武田薬品工業株式会社 メタスチン誘導体およびその用途
US6800611B2 (en) * 2003-01-06 2004-10-05 Takeda Chemical Industries, Ltd. Metastin derivatives and their use
KR100595364B1 (ko) 2003-02-20 2006-07-03 재단법인 목암생명공학연구소 Ｌｋ8 단백질을 유효성분으로 포함하는 항암제
EP1604682A4 (en) * 2003-03-12 2009-06-24 Takeda Chemical Industries Ltd AGENTS IMPROVING GONADIC FUNCTION
EP1464652A1 (en) 2003-04-02 2004-10-06 Institut National De La Sante Et De La Recherche Medicale (Inserm) GPR54 receptor agonist and antagonist useful for the treatment of gonadotropin related diseases
US20050002935A1 (en) 2003-04-17 2005-01-06 Vincent Ling Use of B7-H3 as an immunoregulatory agent
CA2523600A1 (en) 2003-04-28 2004-11-11 Wyeth Methods utilising g-protein coupled receptor 54
WO2004101747A2 (en) 2003-05-07 2004-11-25 The General Hospital Corporation Identification and use of gpr54 and its ligands for reproductive disorders and contraception
US20070155803A1 (en) * 2003-05-30 2007-07-05 Prozymex A/S Protease inhibitors
JP4688678B2 (ja) 2003-11-03 2011-05-25 北京沙東生物技術有限公司 抗癌作用を有する組換えタンパク質、それをコードする遺伝子、及びそれらの使用
RU2333221C2 (ru) 2003-11-03 2008-09-10 Бейцзин Санбио Байотек Ко., Лтд. Рекомбинантный белок, обладающий противораковым действием, кодирующий его ген и его применение
WO2005095973A2 (en) 2004-03-25 2005-10-13 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with g-protein coupled receptor 54 (gpr54)
MXPA06014206A (es) * 2004-06-25 2007-02-14 Takeda Pharmaceutical Derivados de metastina y uso de los mismos.
US7725869B1 (en) * 2005-04-07 2010-05-25 Xilinx, Inc. Method and apparatus for modeling multiple instances of an electronic circuit using an imperative programming language description
WO2007084211A2 (en) 2005-11-11 2007-07-26 The General Hospital Corporation Use of gpr54 ligands for treatment of reproductive disorders, proliferative disorders, and for contraception
US20090093615A1 (en) * 2005-12-22 2009-04-09 Takeda Pharmaceutical Company Limited Metastin derivatives and use thereof
US20090099334A1 (en) * 2005-12-22 2009-04-16 Takeda Pharmaceutical Company Limited Metastin derivatives and use thereof
US8404643B2 (en) * 2005-12-22 2013-03-26 Takeda Pharmaceutical Company Limited Metastin derivatives and use thereof
TWI386417B (zh) 2005-12-22 2013-02-21 Takeda Pharmaceutical 轉移抑素衍生物及其用途
TWI404726B (zh) 2006-10-25 2013-08-11 Takeda Pharmaceutical 腫瘤轉移抑制素衍生物及其用途

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