JP2009520682A5 - - Google Patents

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Publication number
JP2009520682A5
JP2009520682A5 JP2008529406A JP2008529406A JP2009520682A5 JP 2009520682 A5 JP2009520682 A5 JP 2009520682A5 JP 2008529406 A JP2008529406 A JP 2008529406A JP 2008529406 A JP2008529406 A JP 2008529406A JP 2009520682 A5 JP2009520682 A5 JP 2009520682A5
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JP
Japan
Prior art keywords
tyr
compound
azagly
asn
trp
Prior art date
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Application number
JP2008529406A
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English (en)
Japanese (ja)
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JP2009520682A (ja
JP4653840B2 (ja
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Publication date
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Priority claimed from PCT/JP2006/326176 external-priority patent/WO2007072997A1/en
Publication of JP2009520682A publication Critical patent/JP2009520682A/ja
Publication of JP2009520682A5 publication Critical patent/JP2009520682A5/ja
Application granted granted Critical
Publication of JP4653840B2 publication Critical patent/JP4653840B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2008529406A 2005-12-22 2006-12-21 メタスチン誘導体およびその用途 Expired - Fee Related JP4653840B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2005370388 2005-12-22
JP2006275843 2006-10-06
PCT/JP2006/326176 WO2007072997A1 (en) 2005-12-22 2006-12-21 Metastin derivatives and use thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2010182482A Division JP5298087B2 (ja) 2005-12-22 2010-08-17 メタスチン誘導体およびその用途

Publications (3)

Publication Number Publication Date
JP2009520682A JP2009520682A (ja) 2009-05-28
JP2009520682A5 true JP2009520682A5 (enExample) 2010-10-07
JP4653840B2 JP4653840B2 (ja) 2011-03-16

Family

ID=37846230

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2008529406A Expired - Fee Related JP4653840B2 (ja) 2005-12-22 2006-12-21 メタスチン誘導体およびその用途
JP2010182482A Active JP5298087B2 (ja) 2005-12-22 2010-08-17 メタスチン誘導体およびその用途

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2010182482A Active JP5298087B2 (ja) 2005-12-22 2010-08-17 メタスチン誘導体およびその用途

Country Status (29)

Country Link
US (1) US7960348B2 (enExample)
EP (1) EP1963362B1 (enExample)
JP (2) JP4653840B2 (enExample)
KR (1) KR101368607B1 (enExample)
AR (1) AR058584A1 (enExample)
AU (1) AU2006328333B2 (enExample)
BR (1) BRPI0619399B8 (enExample)
CA (1) CA2634647C (enExample)
CR (1) CR10019A (enExample)
CY (1) CY1112353T1 (enExample)
DK (1) DK1963362T3 (enExample)
ES (1) ES2375038T3 (enExample)
GE (1) GEP20115356B (enExample)
HR (1) HRP20110851T1 (enExample)
IL (1) IL190888A (enExample)
JO (1) JO2799B1 (enExample)
MA (1) MA30060B1 (enExample)
ME (1) ME01015B (enExample)
MY (1) MY151967A (enExample)
NO (1) NO341879B1 (enExample)
NZ (1) NZ568322A (enExample)
PE (1) PE20071141A1 (enExample)
PL (1) PL1963362T3 (enExample)
PT (1) PT1963362E (enExample)
RS (1) RS52007B (enExample)
RU (1) RU2430107C2 (enExample)
SI (1) SI1963362T1 (enExample)
TW (1) TWI386417B (enExample)
WO (1) WO2007072997A1 (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20050090420A (ko) 2002-12-26 2005-09-13 다케다 야쿠힌 고교 가부시키가이샤 메타스틴 유도체 및 이의 용도
CA2518541C (en) 2003-03-12 2013-05-21 Takeda Pharmaceutical Company Limited Gonadal function improving agents
WO2006001499A2 (en) * 2004-06-25 2006-01-05 Takeda Pharmaceutical Company Limited Metastin derivatives and use thereof
US8404643B2 (en) 2005-12-22 2013-03-26 Takeda Pharmaceutical Company Limited Metastin derivatives and use thereof
TWI386417B (zh) 2005-12-22 2013-02-21 Takeda Pharmaceutical 轉移抑素衍生物及其用途
US20090093615A1 (en) * 2005-12-22 2009-04-09 Takeda Pharmaceutical Company Limited Metastin derivatives and use thereof
JO3048B1 (ar) 2006-10-25 2016-09-05 Takeda Pharmaceuticals Co مشتقات متاستين واستخدامها
EP2277900A4 (en) * 2008-04-24 2011-08-03 Takeda Pharmaceutical METASTINE DERIVATIVE AND ITS USE
JP5698977B2 (ja) 2008-07-30 2015-04-08 武田薬品工業株式会社 メタスチン誘導体およびその用途
UY32367A (es) * 2008-12-29 2010-07-30 Takeda Pharmaceutical Agente preventivo/terapéutico contra el cáncer
MA33910B1 (fr) * 2009-12-22 2013-01-02 Takeda Pharmaceutcal Company Ltd Formulation à libération prolongée
EA021663B1 (ru) * 2010-06-25 2015-08-31 Такеда Фармасьютикал Компани Лимитед Композиция с замедленным высвобождением, способ ее получения и способ лечения рака
EP2755690B1 (en) 2011-08-04 2020-04-01 Merck Sharp & Dohme B.V. Kisspeptide-pentasaccharide conjugates
WO2014010614A1 (ja) 2012-07-12 2014-01-16 武田薬品工業株式会社 マイクロカプセル粉末の製造方法
WO2015112703A1 (en) * 2014-01-22 2015-07-30 The Johns Hopkins University Compositions and methods for treating diabetes
JP6253146B2 (ja) * 2014-02-04 2017-12-27 国立大学法人山口大学 新規なペプチド誘導体及びこれを含有する医薬
WO2018060501A2 (en) 2016-09-30 2018-04-05 Myovant Sciences Gmbh Methods of treating uterine fibroids and endometriosis
IL311335A (en) 2016-09-30 2024-05-01 Sumitomo Pharma Switzerland Gmbh Methods for treating female infertility
WO2019007383A1 (zh) 2017-07-05 2019-01-10 凯惠科技发展(上海)有限公司 一种肽类化合物、其应用及含其的组合物

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IL74827A (en) 1984-05-21 1989-06-30 Salk Inst For Biological Studi Peptides active as gnrh antagonists and pharmaceutical compositions containing them
MX9100717A (es) 1990-08-24 1992-04-01 Syntex Inc Antagonistas de la bradiquinina
JPH09169735A (ja) 1995-10-19 1997-06-30 Takeda Chem Ind Ltd キノリン誘導体、その製造法および用途
AU7333496A (en) 1995-10-19 1997-05-07 Takeda Chemical Industries Ltd. Quinoline derivatives as gnrh antagonists
JP2000510453A (ja) 1996-04-19 2000-08-15 ノボ ノルディスク アクティーゼルスカブ 成長ホルモン遊離特性を有する化合物
CA2283299A1 (en) 1997-03-07 1998-09-11 Human Genome Sciences, Inc. 186 human secreted proteins
JP4486187B2 (ja) 1998-10-27 2010-06-23 武田薬品工業株式会社 新規ｇ蛋白質共役型レセプター蛋白質、そのｄｎａおよびそのリガンド
US6528054B1 (en) 1998-12-28 2003-03-04 Corixa Corporation Compositions and methods for the therapy and diagnosis of breast cancer
WO2001000228A1 (de) 1999-06-28 2001-01-04 Basf Aktiengesellschaft Verfahren zur verhinderung von tumorwachstum
AU779019B2 (en) 1999-08-02 2005-01-06 Archer-Daniels-Midland Company Metabolic engineering of amino acid production
AU1889101A (en) 1999-12-17 2001-06-25 Takeda Chemical Industries Ltd. Process for producing kiss-1 peptide
CZ20023567A3 (cs) 2000-03-29 2003-11-12 Corixa Corporation Sloučeniny a způsoby pro terapii a diagnostiku karcinomu plic
EP1273658A4 (en) * 2000-03-30 2004-08-11 Takeda Chemical Industries Ltd NEW PROTEIN, THEIR DNA AND METHOD FOR THE PRODUCTION THEREOF
US7834141B1 (en) 2000-03-31 2010-11-16 Theresa Siler-Khodr Non-mammalian GnRH analogs and uses thereof in tumor cell growth regulation and cancer therapy
RU2311920C2 (ru) 2000-09-20 2007-12-10 Корикса Корпорейшн Композиции и способы для лечения и диагностики рака легких
JP2003026601A (ja) 2000-11-29 2003-01-29 Takeda Chem Ind Ltd 医薬組成物およびその製造法
JP2002320496A (ja) 2001-02-26 2002-11-05 Takeda Chem Ind Ltd 新規マウス型ＫｉＳＳ−１レセプタータンパク質およびそのＤＮＡ
WO2002085399A1 (fr) 2001-04-20 2002-10-31 Takeda Chemical Industries, Ltd. Preparations contenant un peptide
CN1509336A (zh) 2001-05-17 2004-06-30 株式会社岛津制作所 肽的制备方法
ATE360034T1 (de) * 2001-09-19 2007-05-15 Takeda Pharmaceutical Antikörper gegen metastin und dessen verwendung zur diagnose von schwangerschaft
CA2472423A1 (en) 2002-01-11 2003-07-24 Takeda Chemical Industries, Ltd. Process for producing kiss-1 peptide
JP2003300906A (ja) 2002-04-12 2003-10-21 Daiichi Fine Chemical Co Ltd がん転移抑制因子の安定化
MXPA05004380A (es) 2002-10-25 2005-11-23 Paradigm Therapeutics Ltd Mamiferos gpr54 knock out y metodos de investigacion que los utilizan.
JP4804714B2 (ja) 2002-12-26 2011-11-02 武田薬品工業株式会社 メタスチン誘導体およびその用途
KR20050090420A (ko) * 2002-12-26 2005-09-13 다케다 야쿠힌 고교 가부시키가이샤 메타스틴 유도체 및 이의 용도
US6800611B2 (en) * 2003-01-06 2004-10-05 Takeda Chemical Industries, Ltd. Metastin derivatives and their use
KR100595364B1 (ko) 2003-02-20 2006-07-03 재단법인 목암생명공학연구소 Ｌｋ8 단백질을 유효성분으로 포함하는 항암제
CA2518541C (en) * 2003-03-12 2013-05-21 Takeda Pharmaceutical Company Limited Gonadal function improving agents
EP1464652A1 (en) 2003-04-02 2004-10-06 Institut National De La Sante Et De La Recherche Medicale (Inserm) GPR54 receptor agonist and antagonist useful for the treatment of gonadotropin related diseases
US20050002935A1 (en) 2003-04-17 2005-01-06 Vincent Ling Use of B7-H3 as an immunoregulatory agent
US20050026224A1 (en) 2003-04-28 2005-02-03 Follettie Maximillian T. Methods and compositions for modulating G-protein coupled receptor 54
WO2004101747A2 (en) 2003-05-07 2004-11-25 The General Hospital Corporation Identification and use of gpr54 and its ligands for reproductive disorders and contraception
WO2004106289A1 (en) 2003-05-30 2004-12-09 Prozymex A/S Protease inhibitors
RU2333221C2 (ru) 2003-11-03 2008-09-10 Бейцзин Санбио Байотек Ко., Лтд. Рекомбинантный белок, обладающий противораковым действием, кодирующий его ген и его применение
CA2544473C (en) 2003-11-03 2013-08-13 Beijing Sunbio Biotech Co., Ltd. A recombinant protein having an anti-cancer effect, its encoding gene and uses thereof
WO2005095973A2 (en) 2004-03-25 2005-10-13 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with g-protein coupled receptor 54 (gpr54)
WO2006001499A2 (en) * 2004-06-25 2006-01-05 Takeda Pharmaceutical Company Limited Metastin derivatives and use thereof
US7725869B1 (en) * 2005-04-07 2010-05-25 Xilinx, Inc. Method and apparatus for modeling multiple instances of an electronic circuit using an imperative programming language description
WO2007084211A2 (en) 2005-11-11 2007-07-26 The General Hospital Corporation Use of gpr54 ligands for treatment of reproductive disorders, proliferative disorders, and for contraception
TWI386417B (zh) 2005-12-22 2013-02-21 Takeda Pharmaceutical 轉移抑素衍生物及其用途
US20090099334A1 (en) * 2005-12-22 2009-04-16 Takeda Pharmaceutical Company Limited Metastin derivatives and use thereof
US8404643B2 (en) * 2005-12-22 2013-03-26 Takeda Pharmaceutical Company Limited Metastin derivatives and use thereof
US20090093615A1 (en) * 2005-12-22 2009-04-09 Takeda Pharmaceutical Company Limited Metastin derivatives and use thereof
JO3048B1 (ar) 2006-10-25 2016-09-05 Takeda Pharmaceuticals Co مشتقات متاستين واستخدامها

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