JP2009518421A5 - - Google Patents

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Publication number
JP2009518421A5
JP2009518421A5 JP2008544466A JP2008544466A JP2009518421A5 JP 2009518421 A5 JP2009518421 A5 JP 2009518421A5 JP 2008544466 A JP2008544466 A JP 2008544466A JP 2008544466 A JP2008544466 A JP 2008544466A JP 2009518421 A5 JP2009518421 A5 JP 2009518421A5
Authority
JP
Japan
Prior art keywords
hydroxy
thiadiazolidin
dioxo
phenyl
trioxo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2008544466A
Other languages
English (en)
Japanese (ja)
Other versions
JP2009518421A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2006/046544 external-priority patent/WO2007067614A1/en
Publication of JP2009518421A publication Critical patent/JP2009518421A/ja
Publication of JP2009518421A5 publication Critical patent/JP2009518421A5/ja
Pending legal-status Critical Current

Links

JP2008544466A 2005-12-08 2006-12-06 １，１，３−トリオキソ−１，２，５−チアジアゾリジンおよびＰＴＰａｓｅ阻害剤としてのそれらの使用 Pending JP2009518421A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US74849305P 2005-12-08 2005-12-08
PCT/US2006/046544 WO2007067614A1 (en) 2005-12-08 2006-12-06 l, l, 3-TRI0X0-l, 2, 5-THIADIAZ0LIDINES AND THEIR USE AS PTP-ASES INHIBITORS

Publications (2)

Publication Number Publication Date
JP2009518421A JP2009518421A (ja) 2009-05-07
JP2009518421A5 true JP2009518421A5 (https=) 2010-01-21

Family

ID=37807759

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008544466A Pending JP2009518421A (ja) 2005-12-08 2006-12-06 １，１，３−トリオキソ−１，２，５−チアジアゾリジンおよびＰＴＰａｓｅ阻害剤としてのそれらの使用

Country Status (10)

Country Link
US (1) US20080293782A1 (https=)
EP (1) EP1960377A1 (https=)
JP (1) JP2009518421A (https=)
KR (1) KR20080074966A (https=)
CN (1) CN101321743A (https=)
AU (1) AU2006321904A1 (https=)
BR (1) BRPI0619547A2 (https=)
CA (1) CA2630448A1 (https=)
RU (1) RU2008127253A (https=)
WO (1) WO2007067614A1 (https=)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA94724C2 (en) * 2005-12-08 2011-06-10 Новартис Аг Thiadiazolidinone derivatives as antidiabetic agents
CA2629819A1 (en) * 2005-12-08 2007-06-14 Novartis Ag 1,2,5-thiazolidine derivatives useful for treating conditions mediated by protein tyrosine phosphatases (ptpase)
UA94921C2 (en) 2005-12-08 2011-06-25 Новартис Аг 1-orthofluorophenyl substituted 1, 2, 5-thiazolidinedione derivatives as ptp-as inhibitors
NZ569329A (en) * 2006-01-30 2011-09-30 Transtech Pharma Inc Substituted imidazole derivatives and their use as PTPase inhibitors
CA2647472A1 (en) 2006-03-31 2007-10-11 Novartis Ag Organic compounds
WO2008067527A1 (en) * 2006-12-01 2008-06-05 Novartis Ag Inhibitors of protein tyrosine phosphatase for the treatment of muscle atrophy and related disorders
JP2011504505A (ja) * 2007-11-21 2011-02-10 デコード ジェネティクス イーエイチエフ 肺および心血管障害を治療するためのビアリールｐｄｅ４抑制剤
JP5809157B2 (ja) 2010-10-08 2015-11-10 持田製薬株式会社 環状アミド誘導体
EP2703393A4 (en) * 2011-04-28 2014-09-24 Mochida Pharm Co Ltd CYCLIC AMIDE DERIVATIVE
JPWO2012147516A1 (ja) 2011-04-28 2014-07-28 持田製薬株式会社 環状アミド誘導体
CN107337635A (zh) * 2017-07-21 2017-11-10 张家港威胜生物医药有限公司 一种酰胺类神经再生药物的制备方法
BR112020026086A2 (pt) * 2018-06-21 2021-03-23 Calico Life Sciences Llc inibidores da proteína tirosina fosfatase e métodos de uso destes
EP4073242A4 (en) 2019-12-12 2024-01-03 Kumquat Biosciences Inc. Compositions and methods for potentiating immune activity
PE20241474A1 (es) * 2021-11-23 2024-07-17 Kumquat Biosciences Inc Compuestos que contienen heteroatomos y usos de estos
JP2025513882A (ja) * 2022-04-14 2025-04-30 ネリオ セラピューティクス，インク． タンパク質チロシンホスファターゼ阻害剤およびその使用
CN117658947B (zh) * 2022-09-06 2026-03-06 杭州中美华东制药有限公司 蛋白酪氨酸磷酸酶抑制作用的5-(取代芳基)-1,2,5-噻二唑啉-3-酮类化合物
AR131413A1 (es) * 2022-12-21 2025-03-19 Bristol Myers Squibb Co Inhibidores de la proteína tirosina fosfatasa, composiciones y métodos de uso
PE20252789A1 (es) 2023-05-24 2025-12-22 Kumquat Biosciences Inc Compuestos heterociclicos y usos de estos
KR20260040037A (ko) * 2023-07-14 2026-03-23 카톨리에케 유니버시테이트 루벤 암 및 대사 질병의 치료를 위한 신규 화합물

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2062558A1 (en) * 1991-03-08 1992-09-09 Prasun K. Chakravarty Heterocyclic compounds bearing acidic functional groups as angiotensin ii antagonists
CA2109524A1 (en) * 1991-05-10 1992-11-11 Prasun K. Chakravarty Acidic aralkyl triazole derivatives active as angiotensin ii antagonists
US5162340A (en) * 1991-05-10 1992-11-10 Merck & Co., Inc. Substituted 1-(2h)-isoquinolinones bearing acidic functional groups as angiotensin ii antagonists
US5958957A (en) * 1996-04-19 1999-09-28 Novo Nordisk A/S Modulators of molecules with phosphotyrosine recognition units
EP1119614B1 (en) * 1998-07-24 2009-12-09 Merck Frosst Canada Ltd. Protein tyrosine phosphatase-1b (ptp-1b) deficient mice and uses thereof
KR100868587B1 (ko) * 2002-04-03 2008-11-12 노파르티스 아게 Ｐｔｐａｓｅ 1ｂ 억제제로서의 5-치환된1,1-디옥소-1,2,5-티아졸리딘-3-온 유도체
GB0225986D0 (en) * 2002-11-07 2002-12-11 Astrazeneca Ab Chemical compounds
GB0227813D0 (en) * 2002-11-29 2003-01-08 Astrazeneca Ab Chemical compounds
EP1594497B1 (en) * 2002-12-30 2009-05-27 Vertex Pharmaceuticals Incorporated Sulfhydantoins as phosphate isosteres for use as phosphatase inhibitors in the treatment of cancer and autoimmune disorders
US7141596B2 (en) * 2003-10-08 2006-11-28 Incyte Corporation Inhibitors of proteins that bind phosphorylated molecules
UA94724C2 (en) * 2005-12-08 2011-06-10 Новартис Аг Thiadiazolidinone derivatives as antidiabetic agents
CA2629819A1 (en) * 2005-12-08 2007-06-14 Novartis Ag 1,2,5-thiazolidine derivatives useful for treating conditions mediated by protein tyrosine phosphatases (ptpase)
UA94921C2 (en) * 2005-12-08 2011-06-25 Новартис Аг 1-orthofluorophenyl substituted 1, 2, 5-thiazolidinedione derivatives as ptp-as inhibitors
CA2647472A1 (en) * 2006-03-31 2007-10-11 Novartis Ag Organic compounds
CA2670491A1 (en) * 2006-12-01 2008-06-12 Novartis Ag Inhibitors of protein tyrosine phosphatase for the promotion of physiological cardiac hypertrophy
AR066820A1 (es) * 2007-06-04 2009-09-16 Novartis Ag Compuestos de tiadiazolidin-3 ona

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