JP2009518005A5 - - Google Patents
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- JP2009518005A5 JP2009518005A5 JP2008542473A JP2008542473A JP2009518005A5 JP 2009518005 A5 JP2009518005 A5 JP 2009518005A5 JP 2008542473 A JP2008542473 A JP 2008542473A JP 2008542473 A JP2008542473 A JP 2008542473A JP 2009518005 A5 JP2009518005 A5 JP 2009518005A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- hybridoma cell
- produced
- cell line
- binding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 102100022153 Tumor necrosis factor receptor superfamily member 4 Human genes 0.000 claims 10
- 101710165473 Tumor necrosis factor receptor superfamily member 4 Proteins 0.000 claims 10
- 210000004408 hybridoma Anatomy 0.000 claims 8
- 125000003275 alpha amino acid group Chemical group 0.000 claims 4
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims 3
- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims 3
- 238000012286 ELISA Assay Methods 0.000 claims 2
- 102000004473 OX40 Ligand Human genes 0.000 claims 2
- 108010042215 OX40 Ligand Proteins 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 2
- 239000005557 antagonist Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 230000005764 inhibitory process Effects 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 230000011664 signaling Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73965905P | 2005-11-25 | 2005-11-25 | |
| US60/739,659 | 2005-11-25 | ||
| PCT/US2006/045522 WO2007062245A2 (en) | 2005-11-25 | 2006-11-27 | Human monoclonal antibody human cd134 (ox40) and methods of making and using same |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013161779A Division JP5802245B2 (ja) | 2005-11-25 | 2013-08-02 | ヒトモノクローナル抗体ヒトｃｄ１３４（ｏｘ４０）ならびにその作製および使用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009518005A JP2009518005A (ja) | 2009-05-07 |
| JP2009518005A5 true JP2009518005A5 (cg-RX-API-DMAC7.html) | 2010-01-14 |
| JP5476517B2 JP5476517B2 (ja) | 2014-04-23 |
Family
ID=38067974
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008542473A Active JP5476517B2 (ja) | 2005-11-25 | 2006-11-27 | ヒトモノクローナル抗体ヒトｃｄ１３４（ｏｘ４０）ならびにその作製および使用方法 |
| JP2013161779A Active JP5802245B2 (ja) | 2005-11-25 | 2013-08-02 | ヒトモノクローナル抗体ヒトｃｄ１３４（ｏｘ４０）ならびにその作製および使用方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013161779A Active JP5802245B2 (ja) | 2005-11-25 | 2013-08-02 | ヒトモノクローナル抗体ヒトｃｄ１３４（ｏｘ４０）ならびにその作製および使用方法 |
Country Status (17)
| Country | Link |
|---|---|
| US (5) | US8283450B2 (cg-RX-API-DMAC7.html) |
| EP (4) | EP3098238B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP5476517B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR101340699B1 (cg-RX-API-DMAC7.html) |
| CN (1) | CN101331150B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2006318329B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2631015C (cg-RX-API-DMAC7.html) |
| DK (1) | DK3345927T5 (cg-RX-API-DMAC7.html) |
| ES (3) | ES2938625T3 (cg-RX-API-DMAC7.html) |
| FI (1) | FI3345927T3 (cg-RX-API-DMAC7.html) |
| HU (3) | HUE037642T2 (cg-RX-API-DMAC7.html) |
| LT (1) | LT3345927T (cg-RX-API-DMAC7.html) |
| PL (3) | PL3098238T3 (cg-RX-API-DMAC7.html) |
| PT (3) | PT3345927T (cg-RX-API-DMAC7.html) |
| SI (1) | SI3345927T1 (cg-RX-API-DMAC7.html) |
| TW (1) | TWI461436B (cg-RX-API-DMAC7.html) |
| WO (1) | WO2007062245A2 (cg-RX-API-DMAC7.html) |
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| US20100136030A1 (en) * | 2007-02-27 | 2010-06-03 | Lamhamedi-Cherradi Salah-Eddine | Antagonist ox40 antibodies and their use in the treatment of inflammatory and autoimmune diseases |
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| AU2016203429B2 (en) * | 2007-12-14 | 2018-01-25 | Bristol-Myers Squibb Company | Binding Molecules to the Human OX40 Receptor |
| EP3239178A1 (en) * | 2007-12-14 | 2017-11-01 | Bristol-Myers Squibb Company | Binding molecules to the human ox40 receptor |
| AU2014202213B2 (en) * | 2007-12-14 | 2016-05-12 | Bristol-Myers Squibb Company | Binding Molecules to the Human OX40 Receptor |
| PT2398498T (pt) | 2009-02-17 | 2018-12-03 | Ucb Biopharma Sprl | Moléculas de anticorpo tendo especificidade para ox40 humano |
| ES2630328T3 (es) * | 2010-08-23 | 2017-08-21 | Board Of Regents, The University Of Texas System | Anticuerpos anti-OX40 y procedimientos de uso de los mismos |
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| CN107915775B (zh) * | 2011-07-11 | 2022-07-12 | 伊克诺斯科学公司 | 结合ox40的抗体及其用途 |
| EP2748199B1 (en) * | 2011-08-23 | 2019-08-28 | Board of Regents, The University of Texas System | Anti-ox40 antibodies and methods of using the same |
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| UA112203C2 (uk) | 2011-11-11 | 2016-08-10 | Юсб Фарма С.А. | Злитий білок біоспецифічного антитіла, який зв'язується з ox40 людини та сироватковим альбуміном людини |
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| JP2016515544A (ja) | 2013-03-18 | 2016-05-30 | バイオセルオーエックス プロダクツ ビー．ブイ． | ヒト化抗ｃｄ１３４（ｏｘ４０）抗体およびその使用 |
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