JP2009510046A5 - - Google Patents
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- JP2009510046A5 JP2009510046A5 JP2008532878A JP2008532878A JP2009510046A5 JP 2009510046 A5 JP2009510046 A5 JP 2009510046A5 JP 2008532878 A JP2008532878 A JP 2008532878A JP 2008532878 A JP2008532878 A JP 2008532878A JP 2009510046 A5 JP2009510046 A5 JP 2009510046A5
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- 239000000499 gel Substances 0.000 description 5
- 238000004458 analytical method Methods 0.000 description 3
- 238000002415 sodium dodecyl sulfate polyacrylamide gel electrophoresis Methods 0.000 description 3
- 238000003556 assay Methods 0.000 description 2
- OWMVSZAMULFTJU-UHFFFAOYSA-N bis-tris Chemical compound OCCN(CCO)C(CO)(CO)CO OWMVSZAMULFTJU-UHFFFAOYSA-N 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000004128 high performance liquid chromatography Methods 0.000 description 1
- 230000010287 polarization Effects 0.000 description 1
- 239000012146 running buffer Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72197405P | 2005-09-30 | 2005-09-30 | |
| GBGB0519923.7A GB0519923D0 (en) | 2005-09-30 | 2005-09-30 | Interleukin-13 antibody composition |
| PCT/GB2006/003650 WO2007036745A2 (en) | 2005-09-30 | 2006-09-29 | Interleukin-13 antibody composition |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013212846A Division JP5820450B2 (ja) | 2005-09-30 | 2013-10-10 | インターロイキン−13抗体組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009510046A JP2009510046A (ja) | 2009-03-12 |
| JP2009510046A5 true JP2009510046A5 (https=) | 2009-07-09 |
Family
ID=37434894
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008532878A Pending JP2009510046A (ja) | 2005-09-30 | 2006-09-29 | インターロイキン−13抗体組成物 |
| JP2013212846A Active JP5820450B2 (ja) | 2005-09-30 | 2013-10-10 | インターロイキン−13抗体組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013212846A Active JP5820450B2 (ja) | 2005-09-30 | 2013-10-10 | インターロイキン−13抗体組成物 |
Country Status (21)
| Country | Link |
|---|---|
| US (3) | US20080248048A1 (https=) |
| EP (1) | EP1942939B2 (https=) |
| JP (2) | JP2009510046A (https=) |
| KR (1) | KR101363777B1 (https=) |
| AU (1) | AU2006296399B2 (https=) |
| BE (1) | BE2021C552I2 (https=) |
| BR (1) | BRPI0616359B8 (https=) |
| CA (1) | CA2623429C (https=) |
| CY (2) | CY1120874T1 (https=) |
| FI (1) | FIC20210042I1 (https=) |
| FR (1) | FR21C1055I2 (https=) |
| GB (1) | GB2430883B (https=) |
| HU (1) | HUS2100053I1 (https=) |
| IL (3) | IL189983A (https=) |
| LT (1) | LTC1942939I2 (https=) |
| LU (1) | LUC00239I2 (https=) |
| NL (1) | NL301143I2 (https=) |
| NO (2) | NO344859B1 (https=) |
| PL (1) | PL1942939T5 (https=) |
| SI (1) | SI1942939T2 (https=) |
| WO (1) | WO2007036745A2 (https=) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8420086B2 (en) * | 2002-12-13 | 2013-04-16 | Immunomedics, Inc. | Camptothecin conjugates of anti-CD22 antibodies for treatment of B cell diseases |
| PL3718564T3 (pl) | 2003-12-23 | 2024-03-18 | Genentech, Inc. | Nowe przeciwciała anty-IL 13 i ich zastosowania |
| WO2007045477A2 (en) | 2005-10-21 | 2007-04-26 | Novartis Ag | Human antibodies against il-13 and therapeutic uses |
| CN102887955A (zh) | 2006-04-05 | 2013-01-23 | 艾博特生物技术有限公司 | 抗体纯化 |
| CA2674608A1 (en) * | 2007-01-09 | 2008-07-17 | Wyeth | Anti-il-13 antibody formulations and uses thereof |
| EP2170268A2 (en) | 2007-06-25 | 2010-04-07 | Amgen, Inc. | Compositions of specific binding agents to hepatocyte growth factor |
| EP2173163A4 (en) * | 2007-07-06 | 2010-12-08 | Glaxosmithkline Llc | ANTIBODY FORMULATIONS |
| UA107557C2 (xx) * | 2007-07-06 | 2015-01-26 | Композиція антитіла офатумумабу | |
| EP2050764A1 (en) | 2007-10-15 | 2009-04-22 | sanofi-aventis | Novel polyvalent bispecific antibody format and uses thereof |
| BRPI0906261A2 (pt) | 2008-03-31 | 2015-07-07 | Genentech Inc | "métodos de diagnóstico de um subtipo de asma em uma amostra de paciente, usos de um agente terapêutico e kits de diagnóstico de um subtipo de asma em uma amostra de paciente" |
| GB0904214D0 (en) | 2009-03-11 | 2009-04-22 | Ucb Pharma Sa | Biological products |
| ES2813398T3 (es) | 2009-10-20 | 2021-03-23 | Abbvie Inc | Aislamiento y purificación de anticuerpos anti-IL-13 usando cromatografía de afinidad a Proteína A |
| RU2578468C2 (ru) | 2010-12-16 | 2016-03-27 | Дженентек, Инк. | Способы диагностики и лечения, связанные с ингибированием th2 |
| TWI719112B (zh) | 2011-03-16 | 2021-02-21 | 賽諾菲公司 | 雙重v區類抗體蛋白質之用途 |
| EA201391489A1 (ru) * | 2011-04-07 | 2014-02-28 | ГЛЭКСОСМИТКЛАЙН ЭлЭлСи | Композиции со сниженной вязкостью |
| SG10201505454SA (en) * | 2011-07-13 | 2015-09-29 | Abbvie Inc | Methods and compositions for treating asthma using anti-il-13 antibodies |
| ES2936387T3 (es) | 2011-10-31 | 2023-03-16 | Hoffmann La Roche | Formulaciones de anticuerpos anti-il13 |
| CN107099581B (zh) | 2012-03-27 | 2021-07-13 | 弗·哈夫曼-拉罗切有限公司 | 预测、诊断和治疗特发性肺纤维化的方法 |
| UA117466C2 (uk) | 2012-12-13 | 2018-08-10 | Мерк Шарп Енд Доме Корп. | СТАБІЛЬНИЙ СКЛАД У ВИГЛЯДІ РОЗЧИНУ АНТИТІЛА ДО IL-23p19 |
| US10023608B1 (en) | 2013-03-13 | 2018-07-17 | Amgen Inc. | Protein purification methods to remove impurities |
| RU2016107435A (ru) | 2013-09-13 | 2017-10-18 | Дженентек, Инк. | Композиции и способы обнаружения и количественного определения белка клеток-хозяев в клеточных линиях и рекомбинантные полипептидные продукты |
| CN120904322A (zh) | 2013-09-13 | 2025-11-07 | 豪夫迈·罗氏有限公司 | 包含纯化的重组多肽的方法和组合物 |
| AR098155A1 (es) | 2013-10-23 | 2016-05-04 | Genentech Inc | Métodos para diagnosticar y tratar trastornos eosinofílicos |
| JP2014062100A (ja) * | 2013-11-05 | 2014-04-10 | Glaxosmithkline Llc | 抗体処方 |
| UA117608C2 (uk) | 2014-02-21 | 2018-08-27 | Дженентек, Інк. | Спосіб лікування еозинофільного захворювання у пацієнта шляхом застосування біспецифічного анти-il-13/il-17 антитіла |
| CN106030304B (zh) * | 2014-02-27 | 2018-02-06 | 得克萨斯大学体系董事会 | 用于分离外来体的方法和组合物 |
| CA2943326A1 (en) | 2014-04-11 | 2015-10-15 | Novartis Ag | Methods of selectively treating asthma using il-13 antagonists |
| AR103173A1 (es) | 2014-12-22 | 2017-04-19 | Novarits Ag | Productos farmacéuticos y composiciones líquidas estables de anticuerpos il-17 |
| JP6247241B2 (ja) * | 2015-02-27 | 2017-12-13 | ノバルティス アーゲー | 抗体処方 |
| MX2017011486A (es) | 2015-03-16 | 2018-06-15 | Genentech Inc | Métodos de detección y cuantificación de il-13 y sus usos en el diagnóstico y tratamiento de enfermedades asociadas a th2. |
| WO2017139290A1 (en) * | 2016-02-10 | 2017-08-17 | Medimmune, Llc | Tralokinumab delivery device |
| JP6871948B2 (ja) | 2016-04-27 | 2021-05-19 | アッヴィ・インコーポレイテッド | 抗il−13抗体を使用する、il−13活性が有害である疾患の治療方法 |
| PT3528838T (pt) | 2016-09-23 | 2023-09-04 | Hoffmann La Roche | Utilizações de antagonistas de il-13 para tratamento de dermatite atópica |
| JOP20190260A1 (ar) | 2017-05-02 | 2019-10-31 | Merck Sharp & Dohme | صيغ ثابتة لأجسام مضادة لمستقبل الموت المبرمج 1 (pd-1) وطرق استخدامها |
| JP7382232B2 (ja) | 2017-05-02 | 2023-11-16 | メルク・シャープ・アンド・ドーム・エルエルシー | 抗lag3抗体の製剤および抗lag3抗体と抗pd-1抗体との共製剤 |
| KR20220098056A (ko) | 2018-02-09 | 2022-07-08 | 제넨테크, 인크. | 비만 세포 매개 염증성 질환에 대한 치료 및 진단 방법 |
| WO2020081408A1 (en) | 2018-10-18 | 2020-04-23 | Merck Sharp & Dohme Corp. | Formulations of anti-rsv antibodies and methods of use thereof |
| MX2021004928A (es) | 2018-10-31 | 2021-06-08 | Merck Sharp & Dohme Llc | Cristales de anticuerpo anti-pd-1 humano y metodos de uso de los mismos. |
| WO2020092015A1 (en) | 2018-11-02 | 2020-05-07 | University Of Rochester | Therapeutic mitigation of epithelial infection |
| EP3876990A4 (en) | 2018-11-07 | 2023-09-06 | Merck Sharp & Dohme LLC | CO-FORMULATIONS OF ANTI-LAG3 ANTIBODIES AND ANTI-PD-1 ANTIBODIES |
| KR20230004489A (ko) | 2020-03-23 | 2023-01-06 | 메디뮨 리미티드 | 아토피 피부염 및 관련 장애의 치료 방법 |
| JP2021147383A (ja) | 2020-03-23 | 2021-09-27 | メドイミューン・リミテッドMedImmune Limited | アトピー性皮膚炎及び関連障害を処置するための方法 |
| GB202108379D0 (en) | 2021-06-11 | 2021-07-28 | Medlmmune Ltd | Methods for treating a topic dermatitis and related disorders |
| TW202325731A (zh) | 2021-08-16 | 2023-07-01 | 美商麥迪紐有限責任公司 | 抗il—13抗體調配物 |
| AU2022345969A1 (en) | 2021-09-15 | 2024-03-07 | Dermira, Inc. | Il-13 inhibitors for the treatment of prurigo nodularis |
| WO2023052408A1 (en) | 2021-09-28 | 2023-04-06 | Medimmune Limited | Methods for treating atopic dermatitis and related disorders |
| WO2025128990A1 (en) | 2023-12-14 | 2025-06-19 | Dermira, Inc. | Il-13 antibodies for the treatment of perennial allergic rhinitis |
| WO2025128984A1 (en) | 2023-12-14 | 2025-06-19 | Dermira, Inc. | Il-13 antibodies for the treatment of chronic rhinosinusitis with nasal polyps |
| TW202600591A (zh) | 2024-03-01 | 2026-01-01 | 美商德米拉股份有限公司 | 用於治療發炎後皮膚色素過多或色素過少之il—13抗體 |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0506574B1 (fr) * | 1991-03-29 | 1995-11-29 | Sanofi | Protéine à activité de type cytokine, ADN recombinant codant pour cette protéine, cellules et microorganismes transformés |
| FR2685919B1 (fr) * | 1992-01-08 | 1994-04-08 | Elf Sanofi | Proteine a activite de type cytokine, adn recombinant codant pour cette proteine, cellules animales transformees. |
| US5596072A (en) * | 1992-08-21 | 1997-01-21 | Schering Corporation | Method of refolding human IL-13 |
| JPH07267994A (ja) * | 1994-03-31 | 1995-10-17 | Snow Brand Milk Prod Co Ltd | 新規蛋白質及びその製造法 |
| JP3414856B2 (ja) * | 1994-08-09 | 2003-06-09 | 株式会社ヤトロン | ジフェニルエーテル化合物の免疫学的測定方法 |
| US5866154A (en) † | 1994-10-07 | 1999-02-02 | The Dupont Merck Pharmaceutical Company | Stabilized naloxone formulations |
| US6428788B1 (en) * | 1995-03-15 | 2002-08-06 | Penn State University | Compositions and methods for specifically targeting tumors |
| AU719513B2 (en) † | 1996-05-04 | 2000-05-11 | Astrazeneca Ab | Monoclonal antibody to CEA, conjugates comprising said antibody, and their therapeutic use in an adept system |
| GB9610992D0 (en) * | 1996-05-24 | 1996-07-31 | Glaxo Group Ltd | Concentrated antibody preparation |
| US6991790B1 (en) * | 1997-06-13 | 2006-01-31 | Genentech, Inc. | Antibody formulation |
| CA2635352C (en) | 1997-06-13 | 2012-09-11 | Genentech, Inc. | Stabilized antibody formulation |
| IL140155A (en) † | 1998-06-09 | 2005-12-18 | Statens Seruminstitut | Process for producing immunoglobulins for intravenous administration and other immunoglobulin products |
| JP3537331B2 (ja) * | 1998-11-17 | 2004-06-14 | 積水化学工業株式会社 | Iv型コラーゲンの免疫測定法及び試薬 |
| ATE414151T1 (de) † | 2000-03-03 | 2008-11-15 | Cambridge Antibody Tech | Antikörper gegen eotaxin und deren verwendung |
| EP1175931A1 (en) † | 2000-07-25 | 2002-01-30 | Computer Cell Culture Center S.A. | Integration of high cell density bioreactor operation with ultra fast on-line downstream processing |
| AU2002355285A1 (en) † | 2001-07-23 | 2003-02-17 | Accurate Polymers, Inc. | High-speed, solid-liquid separation |
| US20040248260A1 (en) | 2001-10-26 | 2004-12-09 | Heavner George A. | IL-13 mutein proteins, antibodies, compositions, methods and uses |
| US20040234499A1 (en) * | 2001-10-26 | 2004-11-25 | David Shealy | Asthma-related anti-IL-13 immunoglobulin derived proteins, compositions, methods and uses |
| CA2464695A1 (en) * | 2001-10-26 | 2003-05-01 | Centocor, Inc. | Il-13 mutein proteins, antibodies, compositions, methods and uses |
| AU2003223497A1 (en) | 2002-04-05 | 2003-10-27 | Centocor, Inc. | Asthma-related anti-il-13 immunoglobulin derived proteins, compositions, methods and uses |
| CN1671741A (zh) * | 2002-06-21 | 2005-09-21 | 拜奥根Idec公司 | 浓缩抗体的缓冲剂制剂及其使用方法 |
| CA2516518A1 (en) † | 2003-02-28 | 2004-09-10 | Lonza Biologics Plc. | Antibody purification by protein a and ion exchange chromatography |
| JPWO2004087761A1 (ja) † | 2003-03-31 | 2006-07-27 | 麒麟麦酒株式会社 | ヒトモノクローナル抗体およびヒトポリクローナル抗体の精製 |
| MXPA05010555A (es) * | 2003-04-04 | 2006-03-09 | Genentech Inc | Formulaciones de proteina y anticuerpo de alta concentracion. |
| GB0407315D0 (en) * | 2003-07-15 | 2004-05-05 | Cambridge Antibody Tech | Human antibody molecules |
| TW200530269A (en) * | 2003-12-12 | 2005-09-16 | Chugai Pharmaceutical Co Ltd | Anti-Mpl antibodies |
| PL3718564T3 (pl) † | 2003-12-23 | 2024-03-18 | Genentech, Inc. | Nowe przeciwciała anty-IL 13 i ich zastosowania |
| CN1234725C (zh) † | 2004-04-07 | 2006-01-04 | 陈志南 | 一种高效快速纯化制备片段抗体的方法 |
| AR049390A1 (es) † | 2004-06-09 | 2006-07-26 | Wyeth Corp | Anticuerpos contra la interleuquina-13 humana y usos de los mismos |
| TWI307630B (en) | 2004-07-01 | 2009-03-21 | Glaxo Group Ltd | Immunoglobulins |
| EP1793856A2 (en) * | 2004-08-20 | 2007-06-13 | Amgen Inc. | Methods and compositions for treating allergic inflammation |
| EP1824886B1 (en) * | 2004-11-17 | 2010-12-22 | Amgen Inc. | Fully human monoclonal antibodies to il-13 |
| US20060171943A1 (en) * | 2005-02-01 | 2006-08-03 | Amgen Inc. | Compositions and methods of treating fibrotic disorders |
| US20130323451A1 (en) † | 2010-10-14 | 2013-12-05 | Ticona Gmbh | Plasticized Polyoxymethylene |
-
2006
- 2006-09-29 AU AU2006296399A patent/AU2006296399B2/en active Active
- 2006-09-29 KR KR1020087010374A patent/KR101363777B1/ko active Active
- 2006-09-29 SI SI200632277T patent/SI1942939T2/sl unknown
- 2006-09-29 PL PL06794604T patent/PL1942939T5/pl unknown
- 2006-09-29 WO PCT/GB2006/003650 patent/WO2007036745A2/en not_active Ceased
- 2006-09-29 CA CA2623429A patent/CA2623429C/en not_active Expired - Fee Related
- 2006-09-29 US US12/067,120 patent/US20080248048A1/en not_active Abandoned
- 2006-09-29 JP JP2008532878A patent/JP2009510046A/ja active Pending
- 2006-09-29 GB GB0619204A patent/GB2430883B/en active Active
- 2006-09-29 BR BRPI0616359A patent/BRPI0616359B8/pt active IP Right Grant
- 2006-09-29 EP EP06794604.6A patent/EP1942939B2/en active Active
-
2008
- 2008-03-06 IL IL189983A patent/IL189983A/en active IP Right Grant
- 2008-04-23 NO NO20081946A patent/NO344859B1/no active Protection Beyond IP Right Term
-
2010
- 2010-12-13 US US12/966,377 patent/US9107945B2/en active Active
-
2013
- 2013-10-10 JP JP2013212846A patent/JP5820450B2/ja active Active
- 2013-12-17 IL IL230005A patent/IL230005A/en active IP Right Grant
-
2015
- 2015-07-14 US US14/798,685 patent/US10358488B2/en active Active
-
2016
- 2016-07-10 IL IL246674A patent/IL246674B/en active IP Right Grant
-
2018
- 2018-07-20 CY CY181100758T patent/CY1120874T1/el unknown
-
2021
- 2021-11-03 NL NL301143C patent/NL301143I2/nl unknown
- 2021-11-05 CY CY2021033C patent/CY2021033I1/el unknown
- 2021-11-09 LU LU00239C patent/LUC00239I2/fr unknown
- 2021-11-12 NO NO2021050C patent/NO2021050I1/no unknown
- 2021-11-16 FR FR21C1055C patent/FR21C1055I2/fr active Active
- 2021-11-17 LT LTPA2021528C patent/LTC1942939I2/lt unknown
- 2021-11-22 BE BE2021C552C patent/BE2021C552I2/nl unknown
- 2021-11-23 FI FIC20210042C patent/FIC20210042I1/fi unknown
- 2021-12-02 HU HUS2100053C patent/HUS2100053I1/hu unknown
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