JP2009506117A5 - - Google Patents
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- JP2009506117A5 JP2009506117A5 JP2008529132A JP2008529132A JP2009506117A5 JP 2009506117 A5 JP2009506117 A5 JP 2009506117A5 JP 2008529132 A JP2008529132 A JP 2008529132A JP 2008529132 A JP2008529132 A JP 2008529132A JP 2009506117 A5 JP2009506117 A5 JP 2009506117A5
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- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 10
- 208000035475 disorder Diseases 0.000 claims 8
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 201000010099 disease Diseases 0.000 claims 2
- 201000001320 Atherosclerosis Diseases 0.000 claims 1
- 208000018565 Hemochromatosis Diseases 0.000 claims 1
- 206010061598 Immunodeficiency Diseases 0.000 claims 1
- 208000029462 Immunodeficiency disease Diseases 0.000 claims 1
- 208000019693 Lung disease Diseases 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 208000002193 Pain Diseases 0.000 claims 1
- 208000030852 Parasitic disease Diseases 0.000 claims 1
- 108060008682 Tumor Necrosis Factor Proteins 0.000 claims 1
- 102000000852 Tumor Necrosis Factor-alpha Human genes 0.000 claims 1
- 208000027418 Wounds and injury Diseases 0.000 claims 1
- 230000002159 abnormal effect Effects 0.000 claims 1
- 239000013543 active substance Substances 0.000 claims 1
- 230000033115 angiogenesis Effects 0.000 claims 1
- 239000010425 asbestos Substances 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 208000015114 central nervous system disease Diseases 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 230000006378 damage Effects 0.000 claims 1
- 230000004064 dysfunction Effects 0.000 claims 1
- 230000007813 immunodeficiency Effects 0.000 claims 1
- 208000014674 injury Diseases 0.000 claims 1
- 208000002780 macular degeneration Diseases 0.000 claims 1
- 238000007911 parenteral administration Methods 0.000 claims 1
- 229910052895 riebeckite Inorganic materials 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 208000017520 skin disease Diseases 0.000 claims 1
- 239000012453 solvate Substances 0.000 claims 1
- 208000011580 syndromic disease Diseases 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71238705P | 2005-08-31 | 2005-08-31 | |
| US60/712,387 | 2005-08-31 | ||
| PCT/US2006/033278 WO2007027527A2 (en) | 2005-08-31 | 2006-08-25 | Isoindole-imide compounds and compositions comprising and methods of using the same |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009506117A JP2009506117A (ja) | 2009-02-12 |
| JP2009506117A5 true JP2009506117A5 (enExample) | 2009-10-08 |
| JP5578785B2 JP5578785B2 (ja) | 2014-08-27 |
Family
ID=37758733
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008529132A Active JP5578785B2 (ja) | 2005-08-31 | 2006-08-25 | イソインドール−イミド化合物及びそれを含有する組成物及びそれの使用法 |
Country Status (24)
| Country | Link |
|---|---|
| US (2) | US20070049618A1 (enExample) |
| EP (1) | EP1919892B1 (enExample) |
| JP (1) | JP5578785B2 (enExample) |
| KR (1) | KR20080042158A (enExample) |
| CN (1) | CN101291924A (enExample) |
| AR (1) | AR055150A1 (enExample) |
| AU (1) | AU2006285144A1 (enExample) |
| BR (1) | BRPI0614995A2 (enExample) |
| CA (3) | CA2620085C (enExample) |
| CR (1) | CR9772A (enExample) |
| DO (1) | DOP2006000193A (enExample) |
| EC (1) | ECSP088332A (enExample) |
| ES (1) | ES2434946T3 (enExample) |
| GT (1) | GT200600398A (enExample) |
| IL (1) | IL189795A0 (enExample) |
| MX (1) | MX2008002765A (enExample) |
| NO (1) | NO20081554L (enExample) |
| PA (1) | PA8693101A1 (enExample) |
| PE (1) | PE20070541A1 (enExample) |
| RU (1) | RU2008112221A (enExample) |
| TW (1) | TW200745078A (enExample) |
| UA (1) | UA91560C2 (enExample) |
| WO (1) | WO2007027527A2 (enExample) |
| ZA (1) | ZA200802490B (enExample) |
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| RS52704B (sr) | 2005-06-30 | 2013-08-30 | Celgene Corporation | Postupci za dobijanje 4-amino-2-(2,6-dioksopiperidin-3-il) izoindolin-1,3-dionskih jedinjenja |
| BRPI0614995A2 (pt) * | 2005-08-31 | 2010-01-12 | Celgene Corp | composto ou um sal, solvato ou estereoisemero farmaceuticamente aceitável do mesmo, composição farmacêutica, uso de uma quantidade terapêutica ou profilaticamente eficaz de um composto ou um sal, solvato ou estereoisemero farmaceuticamente aceitável do mesmo, e, forma de dosagem unitária única |
| US8877780B2 (en) * | 2006-08-30 | 2014-11-04 | Celgene Corporation | 5-substituted isoindoline compounds |
| JP5637852B2 (ja) | 2007-09-26 | 2014-12-10 | セルジーン コーポレイション | ６、７又は８置換キナゾリノン誘導体並びにそれらを含有する組成物及びそれらを使用する方法 |
| US20090148853A1 (en) * | 2007-12-07 | 2009-06-11 | Schafer Peter H | Biomarkers for predicting the sensitivity of cells to immunomodulatory compounds during treatment of non-hodgkin's lymphoma |
| US7964354B2 (en) * | 2007-12-20 | 2011-06-21 | Celgene Corporation | Use of micro-RNA as a biomarker of immunomodulatory drug activity |
| WO2009105256A2 (en) * | 2008-02-20 | 2009-08-27 | Celgene Corporation | Method of treating cancer by administering an immunomodulatory compound in combination with a cd40 antibody or cd40 ligand |
| MX361467B (es) * | 2008-10-29 | 2018-12-06 | Celgene Corp | Compuestos de isoindolina para uso en el tratamiento de cancer. |
| CA3110964A1 (en) | 2009-03-25 | 2010-09-30 | Xiaokui Zhang | Preventing a symptom of graft-versus-host disease using human placenta-derived intermediate natural killer cells |
| EP2436387B1 (en) | 2009-05-25 | 2018-07-25 | Celgene Corporation | Pharmaceutical composition comprising crbn for use in treating a disease of the cerebral cortex |
| CA2786266A1 (en) | 2010-01-05 | 2011-07-14 | Celgene Corporation | A combination of an immunomodulatory compound and an artemisinin or a derivative thereof for treating cancer |
| PL2536706T3 (pl) | 2010-02-11 | 2017-10-31 | Celgene Corp | Pochodne arylometoksyizoindoliny i zawierające je kompozycje oraz sposoby ich zastosowania |
| WO2012135299A1 (en) | 2011-03-28 | 2012-10-04 | Deuteria Pharmaceuticals Inc | 2',6'-dioxo-3'-deutero-piperdin-3-yl-isoindoline compounds |
| EP2699909A1 (en) | 2011-04-18 | 2014-02-26 | Celgene Corporation | Biomarkers for the treatment of multiple myeloma |
| MX353482B (es) | 2011-04-29 | 2018-01-16 | Celgene Corp | Metodos para el tratamiento del cancer y enfermedades inflamatorias utilizando cereblon como predictor. |
| CA3136093C (en) | 2012-06-29 | 2025-07-08 | Celgene Corporation | METHODS FOR DETERMINING THE EFFICACY OF A DRUG USING PROTEINS ASSOCIATED WITH CEREBLON |
| US9587281B2 (en) | 2012-08-14 | 2017-03-07 | Celgene Corporation | Cereblon isoforms and their use as biomarkers for therapeutic treatment |
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- 2006-08-25 BR BRPI0614995-2A patent/BRPI0614995A2/pt not_active IP Right Cessation
- 2006-08-25 CA CA2620085A patent/CA2620085C/en active Active
- 2006-08-25 KR KR1020087007833A patent/KR20080042158A/ko not_active Withdrawn
- 2006-08-25 RU RU2008112221/04A patent/RU2008112221A/ru not_active Application Discontinuation
- 2006-08-25 MX MX2008002765A patent/MX2008002765A/es not_active Application Discontinuation
- 2006-08-25 EP EP06813767.8A patent/EP1919892B1/en active Active
- 2006-08-25 AU AU2006285144A patent/AU2006285144A1/en not_active Abandoned
- 2006-08-25 WO PCT/US2006/033278 patent/WO2007027527A2/en not_active Ceased
- 2006-08-25 CA CA2899923A patent/CA2899923A1/en not_active Abandoned
- 2006-08-25 ES ES06813767T patent/ES2434946T3/es active Active
- 2006-08-25 JP JP2008529132A patent/JP5578785B2/ja active Active
- 2006-08-25 CA CA2822094A patent/CA2822094C/en active Active
- 2006-08-25 CN CNA2006800393786A patent/CN101291924A/zh active Pending
- 2006-08-25 UA UAA200803946A patent/UA91560C2/ru unknown
- 2006-08-25 ZA ZA200802490A patent/ZA200802490B/xx unknown
- 2006-08-30 PA PA20068693101A patent/PA8693101A1/es unknown
- 2006-08-30 TW TW095132015A patent/TW200745078A/zh unknown
- 2006-08-30 US US11/513,563 patent/US20070049618A1/en not_active Abandoned
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