JP2009501233A5 - - Google Patents
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- Publication number
- JP2009501233A5 JP2009501233A5 JP2008521581A JP2008521581A JP2009501233A5 JP 2009501233 A5 JP2009501233 A5 JP 2009501233A5 JP 2008521581 A JP2008521581 A JP 2008521581A JP 2008521581 A JP2008521581 A JP 2008521581A JP 2009501233 A5 JP2009501233 A5 JP 2009501233A5
- Authority
- JP
- Japan
- Prior art keywords
- dvs
- dosage unit
- oral dosage
- super
- bioavailable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000000203 mixture Substances 0.000 claims 25
- 238000013270 controlled release Methods 0.000 claims 8
- 239000000454 talc Substances 0.000 claims 4
- 229910052623 talc Inorganic materials 0.000 claims 4
- 229920000168 Microcrystalline cellulose Polymers 0.000 claims 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims 3
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims 3
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims 3
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims 3
- 229960003943 hypromellose Drugs 0.000 claims 3
- 235000019813 microcrystalline cellulose Nutrition 0.000 claims 3
- 239000008108 microcrystalline cellulose Substances 0.000 claims 3
- 229940016286 microcrystalline cellulose Drugs 0.000 claims 3
- 239000001856 Ethyl cellulose Substances 0.000 claims 2
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 claims 2
- DOOTYTYQINUNNV-UHFFFAOYSA-N Triethyl citrate Chemical compound CCOC(=O)CC(O)(C(=O)OCC)CC(=O)OCC DOOTYTYQINUNNV-UHFFFAOYSA-N 0.000 claims 2
- 230000003111 delayed effect Effects 0.000 claims 2
- 235000019325 ethyl cellulose Nutrition 0.000 claims 2
- 229920001249 ethyl cellulose Polymers 0.000 claims 2
- 229920000642 polymer Polymers 0.000 claims 2
- 238000013268 sustained release Methods 0.000 claims 2
- 239000012730 sustained-release form Substances 0.000 claims 2
- 239000001069 triethyl citrate Substances 0.000 claims 2
- VMYFZRTXGLUXMZ-UHFFFAOYSA-N triethyl citrate Natural products CCOC(=O)C(O)(C(=O)OCC)C(=O)OCC VMYFZRTXGLUXMZ-UHFFFAOYSA-N 0.000 claims 2
- 235000013769 triethyl citrate Nutrition 0.000 claims 2
- 229920003138 Eudragit® L 30 D-55 Polymers 0.000 claims 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims 1
- ORUUBRMVQCKYHB-UHFFFAOYSA-N butanedioic acid;4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol Chemical compound OC(=O)CCC(O)=O.C1CCCCC1(O)C(CN(C)C)C1=CC=C(O)C=C1 ORUUBRMVQCKYHB-UHFFFAOYSA-N 0.000 claims 1
- 239000006185 dispersion Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- GDCRSXZBSIRSFR-UHFFFAOYSA-N ethyl prop-2-enoate;2-methylprop-2-enoic acid Chemical compound CC(=C)C(O)=O.CCOC(=O)C=C GDCRSXZBSIRSFR-UHFFFAOYSA-N 0.000 claims 1
- 239000000945 filler Substances 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical compound [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 claims 1
- 239000000314 lubricant Substances 0.000 claims 1
- 229920003145 methacrylic acid copolymer Polymers 0.000 claims 1
- 229940117841 methacrylic acid copolymer Drugs 0.000 claims 1
- 229910052708 sodium Inorganic materials 0.000 claims 1
- 239000011734 sodium Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US69962305P | 2005-07-15 | 2005-07-15 | |
| PCT/US2006/027106 WO2007011619A2 (en) | 2005-07-15 | 2006-07-13 | Highly bioavailable oral delayed release dosage forms of o-desmethylvenlafaxine succinate |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009501233A JP2009501233A (ja) | 2009-01-15 |
| JP2009501233A5 true JP2009501233A5 (enExample) | 2009-08-27 |
Family
ID=37669348
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008521581A Withdrawn JP2009501233A (ja) | 2005-07-15 | 2006-07-13 | バイオアベイラビリティーの高いｏ−デスメチルベンラファキシンスクシネートの経口用遅延放出投薬形態 |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US20070014859A1 (enExample) |
| EP (1) | EP1904040A2 (enExample) |
| JP (1) | JP2009501233A (enExample) |
| KR (1) | KR20080025405A (enExample) |
| CN (1) | CN101247791A (enExample) |
| AR (1) | AR054833A1 (enExample) |
| AU (1) | AU2006270315A1 (enExample) |
| BR (1) | BRPI0613484A2 (enExample) |
| CA (1) | CA2612960A1 (enExample) |
| CR (1) | CR9626A (enExample) |
| EC (1) | ECSP088106A (enExample) |
| GT (1) | GT200600307A (enExample) |
| IL (1) | IL188313A0 (enExample) |
| MX (1) | MX2008000666A (enExample) |
| NO (1) | NO20080088L (enExample) |
| PE (1) | PE20070192A1 (enExample) |
| RU (1) | RU2007148195A (enExample) |
| SV (1) | SV2008002612A (enExample) |
| TW (1) | TW200740427A (enExample) |
| WO (1) | WO2007011619A2 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ556673A (en) | 2005-02-03 | 2010-03-26 | Gen Hospital Corp | Method for treating gefitinib and/or erlotinib resistant cancer with an EGFR inhibitor |
| ES2335919T3 (es) * | 2005-03-31 | 2010-04-06 | Wyeth | Producto de combinacion de o-desmetilvenlafaxina y bazedosifeno, y sus usos. |
| US20080175873A1 (en) * | 2005-06-02 | 2008-07-24 | Biovail Laboratories International S.R.L. | Modified release composition of at least one form of venlafaxine |
| EP3488866A1 (en) | 2005-11-04 | 2019-05-29 | Wyeth LLC | Antineoplastic combinations with mtor inhibitor, herceptin, and/or hki-272 |
| WO2007067501A1 (en) * | 2005-12-05 | 2007-06-14 | Wyeth | Process for selective synthesis of enantiomers of substituted 1-(2-amino-1-phenyl-ethyl)-cyclohexanols |
| TW200806282A (en) * | 2006-05-05 | 2008-02-01 | Wyeth Corp | Solid dosage formulations |
| US20100210719A1 (en) * | 2007-07-12 | 2010-08-19 | Dr. Reddy's Laboratories Ltd. | O-desmethylvenlafaxine |
| US20100330172A1 (en) * | 2007-10-16 | 2010-12-30 | Alphapharm Pty Ltd | Controlled-release pharmaceutical formulation |
| US8022216B2 (en) | 2007-10-17 | 2011-09-20 | Wyeth Llc | Maleate salts of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide and crystalline forms thereof |
| US20110027324A1 (en) * | 2007-12-10 | 2011-02-03 | Wyeth Llc | O-desmethyl-venlafaxine for treating major depressive disorder |
| ES2531322T3 (es) | 2008-06-17 | 2015-03-13 | Wyeth Llc | Combinaciones antineoplásicas que contienen HKI-272 y vinorelbina |
| EP3175853B1 (en) | 2008-08-04 | 2023-11-01 | Wyeth LLC | Antineoplastic combinations of neratinib and capecitabine |
| CN101716168B (zh) * | 2008-10-09 | 2014-09-17 | 北京德众万全医药科技有限公司 | 一种含有去甲文拉法新的盐的药物组合物及其制备方法 |
| EP2191822A1 (en) * | 2008-11-26 | 2010-06-02 | LEK Pharmaceuticals d.d. | Controlled release pharmaceutical compositions comprising O-desmethyl-venlafaxine |
| PT3000467T (pt) | 2009-04-06 | 2023-03-30 | Wyeth Llc | Regime de tratamento utilizando neratinib para o cancro de mama |
| EP2498751B1 (en) * | 2009-11-09 | 2019-04-03 | Wyeth LLC | Coated drug spheroids and uses thereof for eliminating or reducing conditions such as emesis and diarrhea |
| EP2552419A2 (en) * | 2010-03-31 | 2013-02-06 | Wockhardt Limited | Modified release dosage form comprising desvenlafaxine or salts thereof |
| CN102085197B (zh) * | 2010-12-14 | 2013-08-14 | 北京万生药业有限责任公司 | 一种文拉法辛缓释制剂及其制备方法 |
| WO2012140577A1 (en) | 2011-04-12 | 2012-10-18 | Lupin Limited | Modified release pharmaceutical compositions of desvenlafaxine |
| CN111008356B (zh) * | 2019-11-13 | 2023-06-16 | 成都理工大学 | 一种基于WTSVD算法扣除背景的γ能谱集分析方法 |
| CN114288273B (zh) * | 2022-02-11 | 2022-10-18 | 桂林华信制药有限公司 | 一种盐酸文拉法辛缓释胶囊及其生产工艺 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6274171B1 (en) * | 1996-03-25 | 2001-08-14 | American Home Products Corporation | Extended release formulation of venlafaxine hydrochloride |
| AU5738700A (en) * | 1999-06-15 | 2001-01-02 | American Home Products Corporation | Enantiomers of o-desmethyl venlafaxine |
| AR021347A1 (es) * | 1999-10-20 | 2002-07-17 | Cipla Ltd | Una composicion farmaceutica que contiene acido(s) bisfosfoncio o sal(es) del mismo y un proceso de preparacion de la misma |
| US20030191347A1 (en) * | 2002-03-28 | 2003-10-09 | Rolf Keltjens | Venlafaxine base |
| US6703044B1 (en) * | 2002-10-25 | 2004-03-09 | Dexcel Pharma Tech, Ltd | Venlafaxine formulations |
| ES2277030T3 (es) * | 2003-05-02 | 2007-07-01 | Dexcel Ltd. | Formulacion en comprimidos de venlafaxina de liberacion prolongada. |
| WO2005077340A1 (en) * | 2004-02-06 | 2005-08-25 | Wyeth | Multiparticulate o-desmethylvenlafaxine salts and uses thereof |
| US8394409B2 (en) * | 2004-07-01 | 2013-03-12 | Intellipharmaceutics Corp. | Controlled extended drug release technology |
-
2006
- 2006-07-13 TW TW095125660A patent/TW200740427A/zh unknown
- 2006-07-13 KR KR1020087001067A patent/KR20080025405A/ko not_active Withdrawn
- 2006-07-13 GT GT200600307A patent/GT200600307A/es unknown
- 2006-07-13 SV SV2006002612A patent/SV2008002612A/es unknown
- 2006-07-13 PE PE2006000833A patent/PE20070192A1/es not_active Application Discontinuation
- 2006-07-13 BR BRPI0613484A patent/BRPI0613484A2/pt not_active IP Right Cessation
- 2006-07-13 MX MX2008000666A patent/MX2008000666A/es not_active Application Discontinuation
- 2006-07-13 WO PCT/US2006/027106 patent/WO2007011619A2/en not_active Ceased
- 2006-07-13 AR ARP060103012A patent/AR054833A1/es unknown
- 2006-07-13 US US11/486,324 patent/US20070014859A1/en not_active Abandoned
- 2006-07-13 AU AU2006270315A patent/AU2006270315A1/en not_active Abandoned
- 2006-07-13 CA CA002612960A patent/CA2612960A1/en not_active Abandoned
- 2006-07-13 CN CNA2006800258002A patent/CN101247791A/zh active Pending
- 2006-07-13 EP EP06787061A patent/EP1904040A2/en not_active Withdrawn
- 2006-07-13 JP JP2008521581A patent/JP2009501233A/ja not_active Withdrawn
- 2006-07-13 RU RU2007148195/15A patent/RU2007148195A/ru unknown
-
2007
- 2007-12-20 CR CR9626A patent/CR9626A/es not_active Application Discontinuation
- 2007-12-20 IL IL188313A patent/IL188313A0/en unknown
-
2008
- 2008-01-07 NO NO20080088A patent/NO20080088L/no not_active Application Discontinuation
- 2008-01-14 EC EC2008008106A patent/ECSP088106A/es unknown
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