CN101247791A - O-去甲基文拉法辛琥珀酸盐的高生物可利用的口服缓释剂型 - Google Patents

O-去甲基文拉法辛琥珀酸盐的高生物可利用的口服缓释剂型 Download PDF

Info

Publication number
CN101247791A
CN101247791A CNA2006800258002A CN200680025800A CN101247791A CN 101247791 A CN101247791 A CN 101247791A CN A2006800258002 A CNA2006800258002 A CN A2006800258002A CN 200680025800 A CN200680025800 A CN 200680025800A CN 101247791 A CN101247791 A CN 101247791A
Authority
CN
China
Prior art keywords
dvs
hyperbioavailable
composition according
dosage unit
oral dosage
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2006800258002A
Other languages
English (en)
Chinese (zh)
Inventor
S·M·沙
M·B·法齐
C·R·迪奥里奥
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
Wyeth LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth LLC filed Critical Wyeth LLC
Publication of CN101247791A publication Critical patent/CN101247791A/zh
Pending legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CNA2006800258002A 2005-07-15 2006-07-13 O-去甲基文拉法辛琥珀酸盐的高生物可利用的口服缓释剂型 Pending CN101247791A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69962305P 2005-07-15 2005-07-15
US60/699,623 2005-07-15

Publications (1)

Publication Number Publication Date
CN101247791A true CN101247791A (zh) 2008-08-20

Family

ID=37669348

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2006800258002A Pending CN101247791A (zh) 2005-07-15 2006-07-13 O-去甲基文拉法辛琥珀酸盐的高生物可利用的口服缓释剂型

Country Status (20)

Country Link
US (1) US20070014859A1 (enExample)
EP (1) EP1904040A2 (enExample)
JP (1) JP2009501233A (enExample)
KR (1) KR20080025405A (enExample)
CN (1) CN101247791A (enExample)
AR (1) AR054833A1 (enExample)
AU (1) AU2006270315A1 (enExample)
BR (1) BRPI0613484A2 (enExample)
CA (1) CA2612960A1 (enExample)
CR (1) CR9626A (enExample)
EC (1) ECSP088106A (enExample)
GT (1) GT200600307A (enExample)
IL (1) IL188313A0 (enExample)
MX (1) MX2008000666A (enExample)
NO (1) NO20080088L (enExample)
PE (1) PE20070192A1 (enExample)
RU (1) RU2007148195A (enExample)
SV (1) SV2008002612A (enExample)
TW (1) TW200740427A (enExample)
WO (1) WO2007011619A2 (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101716168A (zh) * 2008-10-09 2010-06-02 北京德众万全医药科技有限公司 一种含有去甲文拉法新的盐的药物组合物及其制备方法
CN102085197A (zh) * 2010-12-14 2011-06-08 北京万生药业有限责任公司 一种文拉法辛缓释制剂及其制备方法
CN102724962A (zh) * 2009-11-09 2012-10-10 惠氏有限责任公司 包衣药物球状体及其用于消除或减少病症比如呕吐和腹泻的用途
CN114288273A (zh) * 2022-02-11 2022-04-08 桂林华信制药有限公司 一种盐酸文拉法辛缓释胶囊及其生产工艺

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA200706804B (en) 2005-02-03 2008-10-29 Gen Hospital Corp Method for treating gefitinib resistant cancer
ES2335919T3 (es) * 2005-03-31 2010-04-06 Wyeth Producto de combinacion de o-desmetilvenlafaxina y bazedosifeno, y sus usos.
US20080175873A1 (en) * 2005-06-02 2008-07-24 Biovail Laboratories International S.R.L. Modified release composition of at least one form of venlafaxine
CA2626326C (en) 2005-11-04 2021-02-16 Wyeth Antineoplastic combinations with mtor inhibitor, herceptin, and/or hki-272
JP2009518407A (ja) * 2005-12-05 2009-05-07 ワイス 置換１−（２−アミノ−１−フェニル−エチル）−シクロヘキサノールのエナンチオマーを選択的に合成するための方法
TW200806282A (en) * 2006-05-05 2008-02-01 Wyeth Corp Solid dosage formulations
BRPI0812501A2 (pt) * 2007-07-12 2015-06-16 Reddys Lab Ltd Dr O-desmetil venlafaxina
CA2702664A1 (en) * 2007-10-16 2009-04-23 Alphapharm Pty Ltd Controlled-release pharmaceutical formulation
US8022216B2 (en) 2007-10-17 2011-09-20 Wyeth Llc Maleate salts of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide and crystalline forms thereof
US20110027324A1 (en) * 2007-12-10 2011-02-03 Wyeth Llc O-desmethyl-venlafaxine for treating major depressive disorder
DK2310011T3 (da) 2008-06-17 2013-10-14 Wyeth Llc Antineoplastiske kombinationer indeholdende hki-272 og vinorelbin
CA2730715C (en) 2008-08-04 2013-10-01 Wyeth Llc Antineoplastic combinations of 4-anilino-3-cyanoquinolines and capecitabine
EP2191822A1 (en) * 2008-11-26 2010-06-02 LEK Pharmaceuticals d.d. Controlled release pharmaceutical compositions comprising O-desmethyl-venlafaxine
KR20140036332A (ko) 2009-04-06 2014-03-25 와이어쓰 엘엘씨 네라티닙을 이용한 유방암의 치료법
BR112012024576A2 (pt) * 2010-03-31 2016-05-31 Wockhardt Ltd composição farmacêutica de liberação modificada compreendendo desvenlafaxina ou sais da mesma e processo para preparação da dita composição
WO2012140577A1 (en) 2011-04-12 2012-10-18 Lupin Limited Modified release pharmaceutical compositions of desvenlafaxine
CN111008356B (zh) * 2019-11-13 2023-06-16 成都理工大学 一种基于WTSVD算法扣除背景的γ能谱集分析方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6274171B1 (en) * 1996-03-25 2001-08-14 American Home Products Corporation Extended release formulation of venlafaxine hydrochloride
WO2000076955A1 (en) * 1999-06-15 2000-12-21 American Home Products Corporation Enantiomers of o-desmethyl venlafaxine
AR021347A1 (es) * 1999-10-20 2002-07-17 Cipla Ltd Una composicion farmaceutica que contiene acido(s) bisfosfoncio o sal(es) del mismo y un proceso de preparacion de la misma
AU2003226752A1 (en) * 2002-03-28 2003-10-13 Synthon B.V. Venlafaxine base
US6703044B1 (en) * 2002-10-25 2004-03-09 Dexcel Pharma Tech, Ltd Venlafaxine formulations
ES2277030T3 (es) * 2003-05-02 2007-07-01 Dexcel Ltd. Formulacion en comprimidos de venlafaxina de liberacion prolongada.
EP1711167A1 (en) * 2004-02-06 2006-10-18 Wyeth Multiparticulate o-desmethylvenlafaxine salts and uses thereof
US8394409B2 (en) * 2004-07-01 2013-03-12 Intellipharmaceutics Corp. Controlled extended drug release technology

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101716168B (zh) * 2008-10-09 2014-09-17 北京德众万全医药科技有限公司 一种含有去甲文拉法新的盐的药物组合物及其制备方法
CN101716168A (zh) * 2008-10-09 2010-06-02 北京德众万全医药科技有限公司 一种含有去甲文拉法新的盐的药物组合物及其制备方法
CN106074445B (zh) * 2009-11-09 2018-12-21 惠氏有限责任公司 包衣药物球状体及其制备消除或减少病症的药物的用途
CN102724962A (zh) * 2009-11-09 2012-10-10 惠氏有限责任公司 包衣药物球状体及其用于消除或减少病症比如呕吐和腹泻的用途
CN106074445A (zh) * 2009-11-09 2016-11-09 惠氏有限责任公司 包衣药物球状体及其用于消除或减少病症比如呕吐和腹泻的用途
CN102724962B (zh) * 2009-11-09 2017-05-17 惠氏有限责任公司 包衣药物球状体及其用于消除或减少病症比如呕吐和腹泻的用途
CN107308130A (zh) * 2009-11-09 2017-11-03 惠氏有限责任公司 包衣药物球状体及消除或减少病症如呕吐和腹泻的用途
CN107441058A (zh) * 2009-11-09 2017-12-08 惠氏有限责任公司 包衣药物球状体及消除或减少病症如呕吐和腹泻的用途
CN107308130B (zh) * 2009-11-09 2021-06-15 惠氏有限责任公司 包衣药物球状体及消除或减少病症如呕吐和腹泻的用途
CN102085197B (zh) * 2010-12-14 2013-08-14 北京万生药业有限责任公司 一种文拉法辛缓释制剂及其制备方法
CN102085197A (zh) * 2010-12-14 2011-06-08 北京万生药业有限责任公司 一种文拉法辛缓释制剂及其制备方法
CN114288273A (zh) * 2022-02-11 2022-04-08 桂林华信制药有限公司 一种盐酸文拉法辛缓释胶囊及其生产工艺
CN114288273B (zh) * 2022-02-11 2022-10-18 桂林华信制药有限公司 一种盐酸文拉法辛缓释胶囊及其生产工艺

Also Published As

Publication number Publication date
PE20070192A1 (es) 2007-03-16
MX2008000666A (es) 2008-03-13
TW200740427A (en) 2007-11-01
AU2006270315A1 (en) 2007-01-25
NO20080088L (no) 2008-04-02
AR054833A1 (es) 2007-07-18
WO2007011619A2 (en) 2007-01-25
US20070014859A1 (en) 2007-01-18
GT200600307A (es) 2008-04-24
EP1904040A2 (en) 2008-04-02
ECSP088106A (es) 2008-02-20
CA2612960A1 (en) 2007-01-25
IL188313A0 (en) 2008-04-13
KR20080025405A (ko) 2008-03-20
CR9626A (es) 2008-04-10
RU2007148195A (ru) 2009-08-20
JP2009501233A (ja) 2009-01-15
SV2008002612A (es) 2008-08-29
BRPI0613484A2 (pt) 2016-11-16
WO2007011619A3 (en) 2007-06-21

Similar Documents

Publication Publication Date Title
CN101247791A (zh) O-去甲基文拉法辛琥珀酸盐的高生物可利用的口服缓释剂型
US8895618B1 (en) Composition and method for treating neurological disease
CA2453263C (en) Pharmaceutical compositions containing terbinafine and use thereof
US20050175698A1 (en) Multiparticulate O-desmethylvenlafaxine salts and uses thereof
AU2002321249A1 (en) Pharmaceutical compositions containing terbinafin and use thereof
WO2007133203A1 (en) Controlled dose drug delivery system
RU2435573C2 (ru) Фармацевтические составы на основе гуанфацина, подходящие для ежедневного введения в виде единичной дозированной формы
WO2014096982A1 (en) Stable pharmaceutical compositions of saxagliptin or salts thereof
US20240299307A1 (en) Extended-release compositions comprising atomoxetine
US20240315962A1 (en) Extended release compositions comprising pyridostigmine
MXPA06008933A (en) Multiparticulate o-desmethylvenlafaxine salts and uses thereof

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication

Open date: 20080820