JP2008546376A5 - - Google Patents
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- Publication number
- JP2008546376A5 JP2008546376A5 JP2008516076A JP2008516076A JP2008546376A5 JP 2008546376 A5 JP2008546376 A5 JP 2008546376A5 JP 2008516076 A JP2008516076 A JP 2008516076A JP 2008516076 A JP2008516076 A JP 2008516076A JP 2008546376 A5 JP2008546376 A5 JP 2008546376A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- nucleic acid
- acid molecule
- change
- epilepsy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2005903146A AU2005903146A0 (en) | 2005-06-16 | Methods for the diagnosis and treatment of epilepsy | |
| PCT/AU2006/000841 WO2006133508A1 (en) | 2005-06-16 | 2006-06-16 | Methods of treatment, and diagnosis of epilepsy by detecting mutations in the scn1a gene |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008546376A JP2008546376A (ja) | 2008-12-25 |
| JP2008546376A5 true JP2008546376A5 (enExample) | 2009-07-30 |
Family
ID=37531886
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008516076A Pending JP2008546376A (ja) | 2005-06-16 | 2006-06-16 | Ｓｃｎ１ａ遺伝子における変異を検出することによっててんかんを診断および処置するための方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20100088778A1 (enExample) |
| EP (1) | EP1904630A4 (enExample) |
| JP (1) | JP2008546376A (enExample) |
| CA (1) | CA2612180A1 (enExample) |
| NZ (1) | NZ564892A (enExample) |
| WO (1) | WO2006133508A1 (enExample) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003904154A0 (en) | 2003-08-07 | 2003-08-21 | Bionomics Limited | Mutations in ion channels |
| NZ530258A (en) * | 2001-07-18 | 2006-01-27 | Bionomics Ltd | Mutations in SCN1A SCN2A SCN3A SCN8A sodium ion channels and their use in diagnosing epilepsy |
| AU2003901425A0 (en) * | 2003-03-27 | 2003-04-10 | Bionomics Limited | A diagnostic method for epilepsy |
| JP5540343B2 (ja) * | 2007-11-06 | 2014-07-02 | 国立大学法人 岡山大学 | 小児てんかん患者における急性脳炎または急性脳症の罹患リスク判定データの取得方法およびその利用 |
| JP5608863B2 (ja) * | 2007-12-28 | 2014-10-15 | 公立大学法人横浜市立大学 | 新生児期〜乳児期発症の難治性てんかんの検出方法 |
| ES2904911T3 (es) | 2009-08-20 | 2022-04-06 | Biosceptre Aust Pty Ltd | Anticuerpos anti-receptor P2X7 y fragmentos de los mismos |
| JP5846372B2 (ja) * | 2010-01-29 | 2016-01-20 | 国立大学法人 岡山大学 | Ｄｒａｖｅｔ症候群の発症可能性の判定方法およびその利用 |
| JP2011188837A (ja) * | 2010-03-16 | 2011-09-29 | Hirosaki Univ | リーシークエンスｄｎａチップおよび最適抗てんかん薬決定方法 |
| JP6023705B2 (ja) * | 2010-06-23 | 2016-11-09 | カッパーアールエヌエー，インコーポレイテッド | ナトリウムチャネル、電位依存性、αサブユニット（ＳＣＮＡ）に対する天然アンチセンス転写物の阻害によるＳＣＮＡ関連疾患の治療 |
| TWI734935B (zh) * | 2011-06-24 | 2021-08-01 | 美商可娜公司 | 上調電壓門控鈉離子通道第Ｉ型α次單元(ＳＣＮ１Ａ)之表現及/或功能之反義寡核苷酸及其用途 |
| US9549909B2 (en) | 2013-05-03 | 2017-01-24 | The Katholieke Universiteit Leuven | Method for the treatment of dravet syndrome |
| KR102245345B1 (ko) * | 2014-09-29 | 2021-04-28 | 조게닉스 인터내셔널 리미티드 | 의약품 배포 제어를 위한 제어 시스템 |
| TW201729807A (zh) * | 2015-10-30 | 2017-09-01 | Ｐｔｃ治療公司 | 用於治療癲癇的方法 |
| KR102604132B1 (ko) * | 2015-12-14 | 2023-11-17 | 콜드스프링하버러보러토리 | 상염색체 우성 정신 지체 5 및 드라베 증후군의 치료를 위한 안티센스 올리고머 |
| KR102688278B1 (ko) | 2015-12-22 | 2024-07-26 | 조게닉스 인터내셔널 리미티드 | 펜플루라민 조성물 및 그 제조 방법 |
| JP2019507111A (ja) | 2015-12-22 | 2019-03-14 | ゾゲニクス インターナショナル リミテッド | 代謝抵抗性フェンフルラミン類縁体およびその使用法 |
| CA3032996C (en) | 2016-08-24 | 2025-05-06 | Zogenix International Ltd | Formulation for inhibiting formation of 5-ht 2b agonists and methods of using same |
| US20210188839A1 (en) * | 2016-11-28 | 2021-06-24 | Praxis Precision Medicines, Inc. | Compounds and their methods of use |
| DK3548033T3 (da) | 2016-11-28 | 2024-07-15 | Praxis Prec Medicines Inc | Forbindelser og deres fremgangsmåde til anvendelse |
| US11261188B2 (en) | 2016-11-28 | 2022-03-01 | Praxis Precision Medicines, Inc. | Fused heteroaryl compounds, and methods thereof for treating diseases, disorders, and conditions relating to aberrant function of a sodium channel |
| CN106719436A (zh) * | 2016-12-20 | 2017-05-31 | 郑州伊美诺生物技术有限公司 | 一种制备单克隆抗体的小鼠模型建立方法 |
| WO2018148745A1 (en) | 2017-02-13 | 2018-08-16 | Praxis Precision Medicines , Inc. | Compounds and their methods of use |
| US11731966B2 (en) | 2017-04-04 | 2023-08-22 | Praxis Precision Medicines, Inc. | Compounds and their methods of use |
| US20200085838A1 (en) * | 2017-05-16 | 2020-03-19 | Praxis Precision Medicines, Inc. | Methods of treating epilepsy and neurodevelopmental disorders |
| WO2019035951A1 (en) | 2017-08-15 | 2019-02-21 | Praxis Precision Medicines, Inc. | COMPOUNDS AND THEIR METHODS OF USE |
| SI3673080T1 (sl) | 2017-08-25 | 2024-03-29 | Stoke Therapeutics, Inc. | Protismiselni oligomeri za zdravljenje bolezenskih stanj in bolezni |
| US10682317B2 (en) | 2017-09-26 | 2020-06-16 | Zogenix International Limited | Ketogenic diet compatible fenfluramine formulation |
| CA3085576A1 (en) | 2017-12-13 | 2019-06-20 | The Research Foundation For The State University Of New York | Peptides and other agents for treating pain and increasing pain sensitivity |
| CA3097335A1 (en) | 2018-05-11 | 2019-11-14 | Zogenix International Limited | Compositions and methods for treating seizure-induced sudden death |
| US12259378B2 (en) | 2018-05-25 | 2025-03-25 | Praxis Precision Medicines, Inc. | Dynamic clamps and methods of use thereof |
| EP3801596A4 (en) * | 2018-05-29 | 2023-01-04 | Evogen, Inc. | BIOMARKERS AND METHODS FOR EVALUATION AND TREATMENT OF EPILEPTIC VS NON-EPILEPTIC SEIZURES / NON-SEIZURES / PSYCHOGENIC NON-EPILEPTIC SEIZURES |
| EP3801535A4 (en) | 2018-05-30 | 2022-03-02 | Praxis Precision Medicines, Inc. | ION CHANNEL MODULATORS |
| CA3110211A1 (en) | 2018-08-20 | 2020-02-27 | Rogcon, Inc. | Antisense oligonucleotides targeting scn2a for the treatment of scn1a encephalopathies |
| EA202092908A1 (ru) | 2018-09-28 | 2021-05-14 | Праксис Пресижн Медсинз, Инк. | Модуляторы ионных каналов |
| AU2019384963B2 (en) | 2018-11-19 | 2022-05-26 | Zogenix International Limited | Methods of treating Rett syndrome using fenfluramine |
| EP3931329A4 (en) * | 2019-02-27 | 2023-12-13 | Stoke Therapeutics, Inc. | Antisense oligomers for treatment of conditions and diseases |
| US11773099B2 (en) | 2019-05-28 | 2023-10-03 | Praxis Precision Medicines, Inc. | Compounds and their methods of use |
| US11505554B2 (en) | 2019-05-31 | 2022-11-22 | Praxis Precision Medicines, Inc. | Substituted pyridines as ion channel modulators |
| US11279700B2 (en) | 2019-05-31 | 2022-03-22 | Praxis Precision Medicines, Inc. | Ion channel modulators |
| US11767325B2 (en) | 2019-11-26 | 2023-09-26 | Praxis Precision Medicines, Inc. | Substituted [1,2,4]triazolo[4,3-a]pyrazines as ion channel modulators |
| AU2021270720A1 (en) | 2020-05-11 | 2022-12-08 | Stoke Therapeutics, Inc. | OPA1 antisense oligomers for treatment of conditions and diseases |
| US11612574B2 (en) | 2020-07-17 | 2023-03-28 | Zogenix International Limited | Method of treating patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) |
| CN116024222B (zh) * | 2022-11-30 | 2023-12-22 | 湖南家辉生物技术有限公司 | 一种导致婴儿严重肌阵挛性癫痫的nac1基因突变体及其应用 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4016043A (en) * | 1975-09-04 | 1977-04-05 | Akzona Incorporated | Enzymatic immunological method for the determination of antigens and antibodies |
| US4172124A (en) * | 1978-04-28 | 1979-10-23 | The Wistar Institute | Method of producing tumor antibodies |
| US4474893A (en) * | 1981-07-01 | 1984-10-02 | The University of Texas System Cancer Center | Recombinant monoclonal antibodies |
| US4971903A (en) * | 1988-03-25 | 1990-11-20 | Edward Hyman | Pyrophosphate-based method and apparatus for sequencing nucleic acids |
| US5331573A (en) * | 1990-12-14 | 1994-07-19 | Balaji Vitukudi N | Method of design of compounds that mimic conformational features of selected peptides |
| US6331614B1 (en) * | 1998-12-23 | 2001-12-18 | Myriad Genetics, Inc. | Human CDC14A gene |
| WO2001038564A2 (en) * | 1999-11-26 | 2001-05-31 | Mcgill University | Loci for idiopathic generalized epilepsy, mutations thereof and method using same to assess, diagnose, prognose or treat epilepsy |
| US6703439B2 (en) * | 2000-02-09 | 2004-03-09 | Mitsui Chemicals, Inc. | Polyolefin resin composition and polyolefin film prepared from the same |
| AUPQ882600A0 (en) * | 2000-07-18 | 2000-08-10 | Bionomics Limited | Mutations in ion channels |
| AUPR220300A0 (en) * | 2000-12-20 | 2001-01-25 | Bionomics Limited | New epilepsy gene |
| NZ530258A (en) * | 2001-07-18 | 2006-01-27 | Bionomics Ltd | Mutations in SCN1A SCN2A SCN3A SCN8A sodium ion channels and their use in diagnosing epilepsy |
| AU2003904154A0 (en) * | 2003-08-07 | 2003-08-21 | Bionomics Limited | Mutations in ion channels |
| US7282336B2 (en) * | 2001-07-18 | 2007-10-16 | Bionomics Limited | Method of diagnosing epilepsy |
| US7709225B2 (en) * | 2001-07-18 | 2010-05-04 | Bionomics Limited | Nucleic acids encoding mutations in sodium channels related to epilepsy |
| AU2002351175A1 (en) * | 2001-11-26 | 2003-06-10 | Bristol-Myers Squibb Company | Novel human g-protein coupled receptor, hgprbmy31, and variants and methods of use thereof |
| AU2003901425A0 (en) * | 2003-03-27 | 2003-04-10 | Bionomics Limited | A diagnostic method for epilepsy |
-
2006
- 2006-06-16 NZ NZ564892A patent/NZ564892A/en not_active IP Right Cessation
- 2006-06-16 CA CA002612180A patent/CA2612180A1/en not_active Abandoned
- 2006-06-16 EP EP06741247A patent/EP1904630A4/en not_active Ceased
- 2006-06-16 WO PCT/AU2006/000841 patent/WO2006133508A1/en not_active Ceased
- 2006-06-16 JP JP2008516076A patent/JP2008546376A/ja active Pending
- 2006-06-16 US US11/922,377 patent/US20100088778A1/en not_active Abandoned
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