JP2008540563A5 - - Google Patents
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- Publication number
- JP2008540563A5 JP2008540563A5 JP2008511366A JP2008511366A JP2008540563A5 JP 2008540563 A5 JP2008540563 A5 JP 2008540563A5 JP 2008511366 A JP2008511366 A JP 2008511366A JP 2008511366 A JP2008511366 A JP 2008511366A JP 2008540563 A5 JP2008540563 A5 JP 2008540563A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- composition
- nebulizer
- mutated
- lung
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/127,438 US20050271660A1 (en) | 2002-09-06 | 2005-05-11 | Nebulization of monoclonal antibodies for treating pulmonary diseases |
| PCT/US2006/018269 WO2006122257A2 (en) | 2005-05-11 | 2006-05-10 | Nebulization of monoclonal antibodies for treating pulmonary diseases |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012193985A Division JP2012233013A (ja) | 2005-05-11 | 2012-09-04 | 肺疾患を処置するためのモノクローナル抗体の霧状化 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008540563A JP2008540563A (ja) | 2008-11-20 |
| JP2008540563A5 true JP2008540563A5 (https=) | 2009-06-04 |
Family
ID=37054603
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008511366A Withdrawn JP2008540563A (ja) | 2005-05-11 | 2006-05-10 | 肺疾患を処置するためのモノクローナル抗体の霧状化 |
| JP2012193985A Pending JP2012233013A (ja) | 2005-05-11 | 2012-09-04 | 肺疾患を処置するためのモノクローナル抗体の霧状化 |
| JP2014125985A Pending JP2014169332A (ja) | 2005-05-11 | 2014-06-19 | 肺疾患を処置するためのモノクローナル抗体の霧状化 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012193985A Pending JP2012233013A (ja) | 2005-05-11 | 2012-09-04 | 肺疾患を処置するためのモノクローナル抗体の霧状化 |
| JP2014125985A Pending JP2014169332A (ja) | 2005-05-11 | 2014-06-19 | 肺疾患を処置するためのモノクローナル抗体の霧状化 |
Country Status (7)
| Country | Link |
|---|---|
| US (5) | US20050271660A1 (https=) |
| EP (1) | EP1881993A2 (https=) |
| JP (3) | JP2008540563A (https=) |
| AU (1) | AU2006243994B2 (https=) |
| CA (1) | CA2608195A1 (https=) |
| NZ (2) | NZ563509A (https=) |
| WO (1) | WO2006122257A2 (https=) |
Families Citing this family (70)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050271660A1 (en) * | 2002-09-06 | 2005-12-08 | Alexion Pharmaceuticals, Inc. | Nebulization of monoclonal antibodies for treating pulmonary diseases |
| US9415102B2 (en) | 2002-09-06 | 2016-08-16 | Alexion Pharmaceuticals, Inc. | High concentration formulations of anti-C5 antibodies |
| JP4601426B2 (ja) * | 2002-09-06 | 2010-12-22 | アレクシオン ファーマシューティカルズ， インコーポレイテッド | 補体成分ｃ５に対する抗体を使用する喘息の処置の方法 |
| US9320792B2 (en) | 2002-11-08 | 2016-04-26 | Ablynx N.V. | Pulmonary administration of immunoglobulin single variable domains and constructs thereof |
| WO2005048982A2 (en) * | 2003-11-17 | 2005-06-02 | Nektar Therapeutics | Efficient introduction of an aerosol into a ventilator circuit |
| BRPI0506629A (pt) | 2004-02-10 | 2007-05-02 | Univ Colorado | inibição do fator b, a via alternativa do sistema complemento e métodos relacionados |
| AU2005304624B2 (en) | 2004-11-12 | 2010-10-07 | Xencor, Inc. | Fc variants with altered binding to FcRn |
| WO2006128006A1 (en) | 2005-05-26 | 2006-11-30 | The Regents Of The University Of Colorado | Inhibition of the alternative complement pathway for treatment of traumatic brain injury, spinal cord injury and related conditions |
| US20070191262A1 (en) * | 2005-11-15 | 2007-08-16 | University Of Iowa Research Foundation | Cancer Therapy and Prevention Based on Modulation of Complement activity |
| US20090220508A1 (en) | 2006-03-15 | 2009-09-03 | Alexion Pharmaceuticals, Inc. | Treatment Of Paroxysmal Nocturnal Hemoglobinuria Patients By An Inhibitor Of Complement |
| PL2061501T3 (pl) * | 2006-09-08 | 2016-01-29 | Volution Immuno Pharmaceuticals Sa | Sposób leczenia zaburzeń oddechowych |
| US8312879B2 (en) * | 2006-10-16 | 2012-11-20 | General Electric Company | Method and apparatus for airway compensation control |
| CN101668773B (zh) | 2007-03-14 | 2016-08-31 | 亚力史制药公司 | 人工程化抗b因子抗体 |
| HRP20150279T1 (hr) * | 2007-12-26 | 2015-05-08 | Xencor, Inc. | Fc inaäśice s promijenjenim vezanjem na fcrn |
| AU2009215846B2 (en) * | 2008-02-19 | 2014-08-14 | The Trustees Of The University Of Pennsylvania | Complement inhibitors as therapeutic agents for treatment of cancer |
| US20220281964A1 (en) * | 2008-02-25 | 2022-09-08 | Xencor, Inc. | Fc VARIANTS WITH ALTERED BINDING TO FcRn |
| US12492253B1 (en) | 2008-02-25 | 2025-12-09 | Xencor, Inc. | Anti-human C5 antibodies |
| CA2742802C (en) | 2008-11-10 | 2019-11-26 | Alexion Pharmaceuticals, Inc. | Methods and compositions for treating complement-associated disorders |
| PT2387583T (pt) * | 2009-01-14 | 2018-12-24 | Ablynx Nv | Administração pulmonar de domínios de variável única de imunoglobulina e construtos dos mesmos |
| GB0904214D0 (en) * | 2009-03-11 | 2009-04-22 | Ucb Pharma Sa | Biological products |
| EP2427497B1 (fr) * | 2009-05-07 | 2016-12-07 | Stallergenes | Utilisation d'immunoglobulines igg1 et/ou de ligands du récepteur cd32 pour le traitement de maladies et manifestations inflammatoires par voie mucosale |
| KR20100123240A (ko) * | 2009-05-15 | 2010-11-24 | 포항공과대학교 산학협력단 | 호흡기 염증성 질환의 치료 또는 예방을 위한 호흡기내 투여용 약학 제제 및 상기 질환의 치료 또는 예방 방법 |
| CA2766565A1 (en) | 2009-06-23 | 2010-12-29 | Alexion Pharmaceuticals, Inc. | Bispecific antibodies that bind to complement proteins |
| WO2011003098A1 (en) | 2009-07-02 | 2011-01-06 | Musc Foundation For Research Development | Methods of stimulating liver regeneration |
| SG182408A1 (en) | 2010-01-11 | 2012-08-30 | Alexion Pharma Inc | Biomarkers of immunomodulatory effects in humans treated with anti-cd200 antibodies |
| DK2533761T3 (da) | 2010-02-11 | 2019-06-24 | Ablynx Nv | Fremgangsmåder og sammensætninger til fremstilling af aerosoler |
| MX340696B (es) | 2010-04-30 | 2016-07-21 | Alexion Pharma Inc | Anticuerpos anti-c5a y metodos para usar los anticuerpos. |
| SG186397A1 (en) | 2010-06-22 | 2013-01-30 | Univ Colorado Regents | Antibodies to the c3d fragment of complement component 3 |
| WO2012030645A1 (en) * | 2010-08-30 | 2012-03-08 | Pulmatrix, Inc. | Respirably dry powder comprising calcium lactate, sodium chloride and leucine |
| BR112013007304B1 (pt) | 2010-09-29 | 2021-12-14 | Pulmatrix, Inc. | Pós secos de cátion de metal monovalente para inalação |
| EP3511339B1 (en) | 2012-02-20 | 2025-04-09 | IPC Research, LLC | Polypeptides binding to human complement c5 |
| TW201400499A (zh) * | 2012-03-12 | 2014-01-01 | Revo Biolog Inc | 抗凝血酶用於治療妊娠毒血症之用途 |
| US9803005B2 (en) | 2012-05-24 | 2017-10-31 | Alexion Pharmaceuticals, Inc. | Humaneered anti-factor B antibody |
| EP2879697A4 (en) | 2012-08-03 | 2016-01-20 | Lfb Usa Inc | USE OF ANTITHROMBIN IN OXYGENATION OF EXTRACORPOREAL MEMBRANE |
| EP3722320A3 (en) | 2012-10-25 | 2020-12-30 | Bioverativ USA Inc. | Anti-complement c1s antibodies and uses thereof |
| DK2914291T3 (da) | 2012-11-02 | 2022-05-16 | Bioverativ Usa Inc | Anti-komplement-c1s-antistoffer og anvendelser deraf |
| US20140170158A1 (en) * | 2012-12-17 | 2014-06-19 | The Johns Hopkins University | Compositions and methods for treating or preventing lung diseases |
| EP2978451B1 (en) | 2013-03-29 | 2019-11-27 | Alexion Pharmaceuticals, Inc. | Compositions and methods for increasing the serum half-life of a therapeutic agent targeting complement c5 |
| AU2014248455B2 (en) | 2013-04-01 | 2018-12-06 | Pulmatrix Operating Company, Inc. | Tiotropium dry powders |
| SI3011345T1 (sl) | 2013-08-07 | 2017-12-29 | Alexion Pharmaceuticals, Inc. | Biomarkerski proteini za atipični hemolitični uremični sindrom (ahus) |
| NZ631007A (en) | 2014-03-07 | 2015-10-30 | Alexion Pharma Inc | Anti-c5 antibodies having improved pharmacokinetics |
| EP3125942B8 (en) | 2014-04-03 | 2021-12-01 | CSL Behring AG | Nebulization of immunoglobulin |
| JP6532034B2 (ja) * | 2015-03-24 | 2019-06-19 | 学校法人関西医科大学 | 鼻腔抵抗の測定方法、鼻腔抵抗及び肺気道抵抗の測定方法及び該方法の実施に用いる測定装置 |
| CA2981321A1 (en) | 2015-04-06 | 2016-10-13 | True North Therapeutics, Inc. | Humanized anti-c1s antibodies and methods of use thereof |
| CA2986957A1 (en) | 2015-06-03 | 2016-12-08 | Children's Hospital Medical Center | Compositions and methods for treating neonatal biliary atresia |
| CA3024618A1 (en) | 2016-05-27 | 2017-11-30 | Alexion Pharmaceuticals, Inc. | Methods for treatment of refractory generalized myasthenia gravis |
| CN116769024A (zh) | 2016-06-14 | 2023-09-19 | 瑞泽恩制药公司 | 抗c5抗体及其用途 |
| CN110300520B (zh) | 2016-10-12 | 2022-10-04 | 美国比奥维拉迪维股份有限公司 | 抗C1s抗体及其使用方法 |
| CN111133006A (zh) | 2017-07-14 | 2020-05-08 | 西托姆克斯治疗公司 | 抗cd166抗体及其用途 |
| DK3658184T5 (da) | 2017-07-27 | 2024-08-26 | Alexion Pharma Inc | Højkoncentrerede anti-c5-antistofformuleringer |
| CN118512588A (zh) | 2017-10-26 | 2024-08-20 | 亚力兄制药公司 | 用于治疗阵发性夜间性血红蛋白尿(pnh)和非典型溶血性尿毒症综合征(ahus)的抗c5抗体的剂量和施用 |
| CA3274059A1 (en) | 2017-12-13 | 2026-03-02 | Regeneron Pharmaceuticals, Inc. | Anti-c5 antibody combinations and uses thereof |
| WO2019126536A1 (en) | 2017-12-20 | 2019-06-27 | Alexion Pharmaceuticals Inc. | Humanized anti-cd200 antibodies and uses thereof |
| EP3802593B1 (en) | 2018-05-31 | 2024-09-11 | Alexion Pharmaceuticals, Inc. | Dosage and administration of anti-c5 antibodies for treatment of paroxysmal nocturnal hemoglobinuria (pnh) in pediatric patients |
| EP3802603A1 (en) | 2018-06-04 | 2021-04-14 | Alexion Pharmaceuticals, Inc. | Dosage and administration of anti-c5 antibodies for treatment of atypical hemolytic uremic syndrome (ahus) in pediatric patients |
| US12312394B2 (en) | 2018-06-28 | 2025-05-27 | Alexion Pharmaceuticals, Inc. | Methods of producing anti-C5 antibodies |
| EP3873602B1 (en) | 2018-10-30 | 2023-12-06 | Alexion Pharmaceuticals, Inc. | Subcutaneous dosage and administration of anti-c5 antibodies for treatment of paroxysmal nocturnal hemoglobinuria (pnh) |
| US20210388070A1 (en) * | 2018-10-30 | 2021-12-16 | Alexion Pharmaceuticals, Inc. | Co-administration of a hyaluronidase and anti-c5 antibody for treatment of complement-associated conditions |
| AU2019397033B2 (en) | 2018-12-12 | 2023-06-29 | Kite Pharma, Inc. | Chimeric antigen receptors and CAR-T cells and methods of use |
| EP3773918A4 (en) | 2019-03-05 | 2022-01-05 | Nkarta, Inc. | CD19 DIRECTED CHIMERIC ANTIGEN RECEPTORS AND THEIR USES IN IMMUNOTHERAPY |
| KR20230005268A (ko) | 2020-04-24 | 2023-01-09 | 밀레니엄 파머슈티컬스 인코퍼레이티드 | 항-cd19 항체 및 이의 용도 |
| US20230277524A1 (en) | 2020-05-22 | 2023-09-07 | Trailhead Biosystems Inc. | Combination therapy for treatment of viral infections |
| AU2021286655A1 (en) | 2020-06-12 | 2023-01-05 | Nkarta, Inc. | Genetically modified natural killer cells for CD70-directed cancer immunotherapy |
| WO2022215054A1 (en) | 2021-04-09 | 2022-10-13 | Takeda Pharmaceutical Company Limited | Antibodies targeting complement factor d and uses therof |
| CA3216770A1 (en) | 2021-04-26 | 2022-11-03 | Tomoki Yoshihara | Anti-clec12a antibodies and uses thereof |
| MX2023011712A (es) | 2021-04-26 | 2023-10-12 | Millennium Pharm Inc | Anticuerpos anti receptor de adhesion acoplado a proteinas g e2 (adgre2) y usos de los mismos. |
| IL311837A (en) | 2021-10-20 | 2024-05-01 | Takeda Pharmaceuticals Co | Compositions targeting bcma and methods of use thereof |
| JP2025508050A (ja) * | 2022-03-07 | 2025-03-21 | ンカルタ・インコーポレイテッド | Ｃｄ７０指向性がん免疫療法のための多重遺伝子編集細胞 |
| EP4507720A1 (en) | 2022-04-14 | 2025-02-19 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Alpha-1-antitrypsin for treating paramyxoviridae or orthomyxoviridae infections |
| CN117100857B (zh) * | 2023-08-15 | 2024-09-10 | 福建医科大学附属协和医院 | 一种抗体金纳米笼载药系统、制备方法和用途 |
Family Cites Families (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4228795A (en) * | 1977-03-08 | 1980-10-21 | Babington Robert S | Apparatus for producing finely divided liquid spray |
| EP0530216A4 (en) * | 1990-04-19 | 1993-06-30 | Medimmune, Inc. | Administration of monoclonal antibodies against respiratory viruses |
| WO1992001473A1 (en) * | 1990-07-19 | 1992-02-06 | The United States Of America, As Represented By The Secretary, U.S. Department Of Commerce | Improved immunotherapeutic method of preventing or treating viral respiratory tract disease |
| US5871734A (en) * | 1992-01-13 | 1999-02-16 | Biogen, Inc. | Treatment for asthma with VLA-4 blocking agents |
| DE69328098T2 (de) | 1992-06-24 | 2000-08-24 | Adprotech Plc, Royston | Lösliche derivate des complement type-rezeptors (cr1) |
| US5614370A (en) * | 1994-03-18 | 1997-03-25 | Merck & Co., Inc. | Assay to identify human C5a antagonists and agonists |
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| DE69534701T2 (de) | 1994-09-23 | 2006-10-19 | Alexion Pharmaceuticals, Inc., Cheshire | Verfahren zur behandlung von entzündlichen gelenkerkrankungen |
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| EP0934341A1 (en) | 1996-10-28 | 1999-08-11 | Farmac Nederland B.V. | Inclusion complexes of beta-2-andrenergics for oral mucosal delivery |
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| CA2362338A1 (en) * | 1998-07-30 | 2000-02-10 | Human Rt. | Pharmaceutically acceptable composition comprising an aqueous solution of paclitaxel and albumin |
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| KR100919593B1 (ko) * | 2000-06-29 | 2009-09-29 | 아보트 러보러터리즈 | 이중 특이성 항체 및 이의 제조 방법 및 이를 포함하는 조성물 |
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| JP4601426B2 (ja) * | 2002-09-06 | 2010-12-22 | アレクシオン ファーマシューティカルズ， インコーポレイテッド | 補体成分ｃ５に対する抗体を使用する喘息の処置の方法 |
| US9415102B2 (en) | 2002-09-06 | 2016-08-16 | Alexion Pharmaceuticals, Inc. | High concentration formulations of anti-C5 antibodies |
| US20030124139A1 (en) * | 2002-11-20 | 2003-07-03 | Irina Esikova | Compositions and methods for stabilizing biological molecules upon lyophilization |
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| DK2236154T3 (en) * | 2003-02-10 | 2018-06-25 | Biogen Ma Inc | IMMUNOGLOBULIN INFORMATION AND METHOD OF PREPARING IT |
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| CA2638811A1 (en) * | 2006-02-03 | 2007-08-16 | Medimmune, Llc | Protein formulations |
| US20090220508A1 (en) | 2006-03-15 | 2009-09-03 | Alexion Pharmaceuticals, Inc. | Treatment Of Paroxysmal Nocturnal Hemoglobinuria Patients By An Inhibitor Of Complement |
| CA2674608A1 (en) * | 2007-01-09 | 2008-07-17 | Wyeth | Anti-il-13 antibody formulations and uses thereof |
| JP4538514B2 (ja) | 2008-07-30 | 2010-09-08 | シャープ株式会社 | 画像圧縮方法、画像圧縮装置、画像形成装置、コンピュータプログラム及び記録媒体 |
| CA2742802C (en) | 2008-11-10 | 2019-11-26 | Alexion Pharmaceuticals, Inc. | Methods and compositions for treating complement-associated disorders |
| US20100278822A1 (en) | 2009-05-04 | 2010-11-04 | Abbott Biotechnology, Ltd. | Stable high protein concentration formulations of human anti-tnf-alpha-antibodies |
-
2005
- 2005-05-11 US US11/127,438 patent/US20050271660A1/en not_active Abandoned
-
2006
- 2006-05-10 NZ NZ563509A patent/NZ563509A/en not_active IP Right Cessation
- 2006-05-10 CA CA002608195A patent/CA2608195A1/en not_active Abandoned
- 2006-05-10 NZ NZ582627A patent/NZ582627A/en unknown
- 2006-05-10 AU AU2006243994A patent/AU2006243994B2/en not_active Ceased
- 2006-05-10 WO PCT/US2006/018269 patent/WO2006122257A2/en not_active Ceased
- 2006-05-10 EP EP06759586A patent/EP1881993A2/en not_active Withdrawn
- 2006-05-10 JP JP2008511366A patent/JP2008540563A/ja not_active Withdrawn
-
2012
- 2012-09-04 JP JP2012193985A patent/JP2012233013A/ja active Pending
-
2014
- 2014-06-19 JP JP2014125985A patent/JP2014169332A/ja active Pending
-
2017
- 2017-08-11 US US15/675,074 patent/US10125191B2/en not_active Expired - Lifetime
-
2018
- 2018-10-04 US US16/152,235 patent/US10479828B2/en not_active Expired - Lifetime
-
2019
- 2019-10-09 US US16/597,040 patent/US10927166B2/en not_active Expired - Lifetime
-
2021
- 2021-01-19 US US17/152,054 patent/US20210214427A1/en not_active Abandoned
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