JP2008537675A5 - - Google Patents
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- Publication number
- JP2008537675A5 JP2008537675A5 JP2008501161A JP2008501161A JP2008537675A5 JP 2008537675 A5 JP2008537675 A5 JP 2008537675A5 JP 2008501161 A JP2008501161 A JP 2008501161A JP 2008501161 A JP2008501161 A JP 2008501161A JP 2008537675 A5 JP2008537675 A5 JP 2008537675A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- amino acids
- nucleotides
- polypeptide
- polypeptide according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 235000001014 amino acid Nutrition 0.000 claims 56
- 150000001413 amino acids Chemical class 0.000 claims 56
- 239000002773 nucleotide Substances 0.000 claims 47
- 125000003729 nucleotide group Chemical group 0.000 claims 47
- 229920001184 polypeptide Polymers 0.000 claims 32
- 102000004196 processed proteins & peptides Human genes 0.000 claims 32
- 108090000765 processed proteins & peptides Proteins 0.000 claims 32
- 108091033319 polynucleotide Proteins 0.000 claims 7
- 102000040430 polynucleotide Human genes 0.000 claims 7
- 239000002157 polynucleotide Substances 0.000 claims 7
- 238000004519 manufacturing process Methods 0.000 claims 6
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 5
- 230000000845 anti-microbial effect Effects 0.000 claims 5
- 125000003275 alpha amino acid group Chemical group 0.000 claims 4
- 108020004707 nucleic acids Proteins 0.000 claims 4
- 102000039446 nucleic acids Human genes 0.000 claims 4
- 150000007523 nucleic acids Chemical class 0.000 claims 4
- 230000000844 anti-bacterial effect Effects 0.000 claims 3
- 230000000295 complement effect Effects 0.000 claims 3
- 230000000813 microbial effect Effects 0.000 claims 3
- 239000004599 antimicrobial Substances 0.000 claims 2
- 238000012258 culturing Methods 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 230000009261 transgenic effect Effects 0.000 claims 2
- 108091026890 Coding region Proteins 0.000 claims 1
- 108020004414 DNA Proteins 0.000 claims 1
- 102000000541 Defensins Human genes 0.000 claims 1
- 108010002069 Defensins Proteins 0.000 claims 1
- 241001465754 Metazoa Species 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 125000000151 cysteine group Chemical group N[C@@H](CS)C(=O)* 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000013604 expression vector Substances 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 230000035772 mutation Effects 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 230000000069 prophylactic effect Effects 0.000 claims 1
- 238000003259 recombinant expression Methods 0.000 claims 1
- 229940124597 therapeutic agent Drugs 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
Applications Claiming Priority (21)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200500392 | 2005-03-18 | ||
| DKPA200500392 | 2005-03-18 | ||
| DKPA200501033 | 2005-07-14 | ||
| DKPA200501032 | 2005-07-14 | ||
| DKPA200501034 | 2005-07-14 | ||
| DKPA200501034 | 2005-07-14 | ||
| DKPA200501038 | 2005-07-14 | ||
| DKPA200501038 | 2005-07-14 | ||
| DKPA200501037 | 2005-07-14 | ||
| DKPA200501036 | 2005-07-14 | ||
| DKPA200501037 | 2005-07-14 | ||
| DKPA200501035 | 2005-07-14 | ||
| DKPA200501033 | 2005-07-14 | ||
| DKPA200501032 | 2005-07-14 | ||
| DKPA200501036 | 2005-07-14 | ||
| DKPA200501035 | 2005-07-14 | ||
| DKPA200501367 | 2005-09-30 | ||
| DKPA200501367 | 2005-09-30 | ||
| DKPA200501365 | 2005-09-30 | ||
| DKPA200501365 | 2005-09-30 | ||
| PCT/DK2006/000155 WO2006097110A2 (en) | 2005-03-18 | 2006-03-20 | Polypeptides having antimicrobial activity and polynucleotides encoding same |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012151360A Division JP2012191951A (ja) | 2005-03-18 | 2012-07-05 | 抗菌活性を有するポリペプチド及びそれをコードするポリヌクレオチド |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008537675A JP2008537675A (ja) | 2008-09-25 |
| JP2008537675A5 true JP2008537675A5 (enExample) | 2009-05-21 |
| JP5080440B2 JP5080440B2 (ja) | 2012-11-21 |
Family
ID=36235484
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008501161A Expired - Fee Related JP5080440B2 (ja) | 2005-03-18 | 2006-03-20 | 抗菌活性を有するポリペプチド及びそれをコードするポリヌクレオチド |
| JP2012151360A Pending JP2012191951A (ja) | 2005-03-18 | 2012-07-05 | 抗菌活性を有するポリペプチド及びそれをコードするポリヌクレオチド |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012151360A Pending JP2012191951A (ja) | 2005-03-18 | 2012-07-05 | 抗菌活性を有するポリペプチド及びそれをコードするポリヌクレオチド |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1863836B1 (enExample) |
| JP (2) | JP5080440B2 (enExample) |
| AR (1) | AR052947A1 (enExample) |
| AU (1) | AU2006224944B2 (enExample) |
| CA (1) | CA2601525A1 (enExample) |
| TW (1) | TW200700076A (enExample) |
| WO (1) | WO2006097110A2 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI1922333T1 (sl) * | 2005-08-26 | 2010-06-30 | Novozymes Adenium Biotech As | Polipeptidi z antimikrobno aktivnostjo in polinukleotidi ki kodirajo le te |
| CN101704886B (zh) * | 2009-11-17 | 2012-03-21 | 中国人民解放军第三军医大学 | 人α-防御素5抗病毒活性突变体多肽及制备方法和应用 |
| WO2011104284A1 (en) * | 2010-02-25 | 2011-09-01 | Novozymes A/S | Polypeptides having antimicrobial activity |
| US8835604B2 (en) | 2010-06-12 | 2014-09-16 | Adenium Biotech Aos | Antimicrobial peptide variants and polynucleotides encoding same |
| US10568930B2 (en) | 2014-04-24 | 2020-02-25 | Hexima Limited | Agents and methods of treatment |
| RU2597789C2 (ru) * | 2014-11-10 | 2016-09-20 | Илья Владимирович Духовлинов | Анальгетическое средство на основе плазмидной днк, кодирующей hnp-1, либо hnp-2, либо hnp-3 (варианты) |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| IL99552A0 (en) | 1990-09-28 | 1992-08-18 | Ixsys Inc | Compositions containing procaryotic cells,a kit for the preparation of vectors useful for the coexpression of two or more dna sequences and methods for the use thereof |
| US6592876B1 (en) * | 1993-04-20 | 2003-07-15 | Uab Research Foundation | Pneumococcal genes, portions thereof, expression products therefrom, and uses of such genes, portions and products |
| DE4343591A1 (de) | 1993-12-21 | 1995-06-22 | Evotec Biosystems Gmbh | Verfahren zum evolutiven Design und Synthese funktionaler Polymere auf der Basis von Formenelementen und Formencodes |
| US5605793A (en) | 1994-02-17 | 1997-02-25 | Affymax Technologies N.V. | Methods for in vitro recombination |
| IL114697A0 (en) * | 1994-07-22 | 1995-11-27 | Demeter Biotech Ltd | Polypeptides comprising ubiquitin-lytic peptide fusion protein products deriving therefrom their preparation and use |
| GB9526238D0 (en) * | 1995-12-21 | 1996-02-21 | Sandoz Ltd | Improvements in or relating to organic compounds |
| WO1998058061A1 (en) * | 1997-06-19 | 1998-12-23 | Schering Corporation | Mammalian genes; related reagents |
| US7338937B2 (en) * | 1997-11-17 | 2008-03-04 | Cornell Research Foundation, Inc. | Calcium-activated chloride channel proteins and their use in anti-metastatic therapy |
| FR2777568B1 (fr) | 1998-04-15 | 2002-10-31 | Rhone Poulenc Agrochimie | Gene codant pour l'heliomicine, proteine obtenue, vecteur le contenant, organismes transformes obtenus et procede de preparation |
| US6335318B1 (en) * | 1999-05-10 | 2002-01-01 | The Regents Of The University Of California | Antimicrobial theta defensins and methods of using same |
| JP4972264B2 (ja) * | 1999-12-06 | 2012-07-11 | ボード オブ トラスティーズ オブ ザ ユニバーシティ オブ イリノイ | 高親和性ｔｃｒタンパク質および方法 |
| GB0026002D0 (en) * | 2000-10-24 | 2000-12-13 | Smithkline Beecham Biolog | Novel compounds |
| FR2823754B1 (fr) | 2001-04-19 | 2004-02-13 | Entomed | Peptides antibacteriens, les compositions les contenant et leurs utilisations |
| NZ532962A (en) | 2001-11-20 | 2006-11-30 | Novozymes As | Antimicrobial polypeptides from pseudoplectania nigrella |
| JP2004329215A (ja) * | 2004-06-07 | 2004-11-25 | National Agriculture & Bio-Oriented Research Organization | 複合病害抵抗性を有する植物 |
-
2006
- 2006-03-20 WO PCT/DK2006/000155 patent/WO2006097110A2/en not_active Ceased
- 2006-03-20 JP JP2008501161A patent/JP5080440B2/ja not_active Expired - Fee Related
- 2006-03-20 EP EP06706125A patent/EP1863836B1/en active Active
- 2006-03-20 AR ARP060101082A patent/AR052947A1/es not_active Application Discontinuation
- 2006-03-20 AU AU2006224944A patent/AU2006224944B2/en not_active Ceased
- 2006-03-20 CA CA002601525A patent/CA2601525A1/en not_active Abandoned
- 2006-03-20 TW TW095109518A patent/TW200700076A/zh unknown
-
2012
- 2012-07-05 JP JP2012151360A patent/JP2012191951A/ja active Pending
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