JP2008519585A5 - - Google Patents

Info

Publication number

JP2008519585A5

JP2008519585A5 JP2007540495A JP2007540495A JP2008519585A5 JP 2008519585 A5 JP2008519585 A5 JP 2008519585A5 JP 2007540495 A JP2007540495 A JP 2007540495A JP 2007540495 A JP2007540495 A JP 2007540495A JP 2008519585 A5 JP2008519585 A5 JP 2008519585A5

Authority

JP

Japan

Prior art keywords

polypeptide

seq

amino acids

nucleotides

polynucleotide

Prior art date

2005-11-11

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

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• 229920001184 polypeptide Polymers 0.000 claims 30
• 102000004196 processed proteins & peptides Human genes 0.000 claims 30
• 108090000765 processed proteins & peptides Proteins 0.000 claims 30
• 150000001413 amino acids Chemical class 0.000 claims 11
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 9
• 239000002773 nucleotide Substances 0.000 claims 8
• 125000003729 nucleotide group Chemical group 0.000 claims 8
• 108091033319 polynucleotide Proteins 0.000 claims 8
• 102000040430 polynucleotide Human genes 0.000 claims 8
• 239000002157 polynucleotide Substances 0.000 claims 8
• 238000004519 manufacturing process Methods 0.000 claims 5
• 125000003275 alpha amino acid group Chemical group 0.000 claims 4
• 230000000844 anti-bacterial effect Effects 0.000 claims 4
• 230000000845 anti-microbial effect Effects 0.000 claims 3
• 230000000295 complement effect Effects 0.000 claims 3
• 239000002299 complementary DNA Substances 0.000 claims 3
• 230000000813 microbial effect Effects 0.000 claims 3
• 108020004707 nucleic acids Proteins 0.000 claims 3
• 102000039446 nucleic acids Human genes 0.000 claims 3
• 150000007523 nucleic acids Chemical class 0.000 claims 3
• 239000004599 antimicrobial Substances 0.000 claims 2
• 238000012258 culturing Methods 0.000 claims 2
• 230000037430 deletion Effects 0.000 claims 2
• 238000012217 deletion Methods 0.000 claims 2
• 239000003814 drug Substances 0.000 claims 2
• 230000037431 insertion Effects 0.000 claims 2
• 238000003780 insertion Methods 0.000 claims 2
• 238000006467 substitution reaction Methods 0.000 claims 2
• 230000009261 transgenic effect Effects 0.000 claims 2
• 238000005406 washing Methods 0.000 claims 2
• 108091026890 Coding region Proteins 0.000 claims 1
• 108020004414 DNA Proteins 0.000 claims 1
• 241001465754 Metazoa Species 0.000 claims 1
• 229940126573 antibacterial therapeutic Drugs 0.000 claims 1
• 239000003795 chemical substances by application Substances 0.000 claims 1
• 239000013604 expression vector Substances 0.000 claims 1
• 208000015181 infectious disease Diseases 0.000 claims 1
• 230000002401 inhibitory effect Effects 0.000 claims 1
• 238000000034 method Methods 0.000 claims 1
• 230000035772 mutation Effects 0.000 claims 1
• 238000002360 preparation method Methods 0.000 claims 1
• 230000002265 prevention Effects 0.000 claims 1
• 230000000069 prophylactic effect Effects 0.000 claims 1
• 238000003259 recombinant expression Methods 0.000 claims 1
• 229940124597 therapeutic agent Drugs 0.000 claims 1