JP2008534672A5 - - Google Patents
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- Publication number
- JP2008534672A5 JP2008534672A5 JP2008504870A JP2008504870A JP2008534672A5 JP 2008534672 A5 JP2008534672 A5 JP 2008534672A5 JP 2008504870 A JP2008504870 A JP 2008504870A JP 2008504870 A JP2008504870 A JP 2008504870A JP 2008534672 A5 JP2008534672 A5 JP 2008534672A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutically acceptable
- pharmaceutical composition
- compound
- acceptable salt
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 150000001875 compounds Chemical class 0.000 claims 14
- 239000008194 pharmaceutical composition Substances 0.000 claims 11
- 150000003839 salts Chemical class 0.000 claims 10
- 208000035143 Bacterial infection Diseases 0.000 claims 5
- 208000022362 bacterial infectious disease Diseases 0.000 claims 5
- 241000894006 Bacteria Species 0.000 claims 3
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 3
- 241000588621 Moraxella Species 0.000 claims 2
- 241000186367 Mycobacterium avium Species 0.000 claims 2
- 230000037396 body weight Effects 0.000 claims 2
- 125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 claims 2
- 125000004186 cyclopropylmethyl group Chemical group [H]C([H])(*)C1([H])C([H])([H])C1([H])[H] 0.000 claims 2
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 2
- 241000606125 Bacteroides Species 0.000 claims 1
- 241000606161 Chlamydia Species 0.000 claims 1
- 241001112695 Clostridiales Species 0.000 claims 1
- 208000008960 Diabetic foot Diseases 0.000 claims 1
- 206010014666 Endocarditis bacterial Diseases 0.000 claims 1
- 241000194033 Enterococcus Species 0.000 claims 1
- 241000194032 Enterococcus faecalis Species 0.000 claims 1
- 208000001860 Eye Infections Diseases 0.000 claims 1
- 241000192125 Firmicutes Species 0.000 claims 1
- 241000606790 Haemophilus Species 0.000 claims 1
- 241000606768 Haemophilus influenzae Species 0.000 claims 1
- 241000124008 Mammalia Species 0.000 claims 1
- 241000588655 Moraxella catarrhalis Species 0.000 claims 1
- 206010031252 Osteomyelitis Diseases 0.000 claims 1
- 208000005141 Otitis Diseases 0.000 claims 1
- 206010057190 Respiratory tract infections Diseases 0.000 claims 1
- 241000295644 Staphylococcaceae Species 0.000 claims 1
- 241000191940 Staphylococcus Species 0.000 claims 1
- 241000191967 Staphylococcus aureus Species 0.000 claims 1
- 241000191963 Staphylococcus epidermidis Species 0.000 claims 1
- 241000194017 Streptococcus Species 0.000 claims 1
- 241000193998 Streptococcus pneumoniae Species 0.000 claims 1
- 241000193996 Streptococcus pyogenes Species 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 208000009361 bacterial endocarditis Diseases 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 208000019258 ear infection Diseases 0.000 claims 1
- 206010014665 endocarditis Diseases 0.000 claims 1
- 208000011323 eye infectious disease Diseases 0.000 claims 1
- 229910052731 fluorine Inorganic materials 0.000 claims 1
- 125000001153 fluoro group Chemical group F* 0.000 claims 1
- 125000003784 fluoroethyl group Chemical group [H]C([H])(F)C([H])([H])* 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 201000007119 infective endocarditis Diseases 0.000 claims 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 claims 1
- 230000003902 lesion Effects 0.000 claims 1
- RYXZVPPFWXWUKQ-JTQLQIEISA-N methyl n-[[(5s)-3-(7-fluoro-1-methyl-2-oxo-3h-indol-5-yl)-2-oxo-1,3-oxazolidin-5-yl]methyl]carbamate Chemical compound O=C1O[C@@H](CNC(=O)OC)CN1C(C=C1F)=CC2=C1N(C)C(=O)C2 RYXZVPPFWXWUKQ-JTQLQIEISA-N 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 claims 1
- 230000000699 topical effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US66871505P | 2005-04-06 | 2005-04-06 | |
| US68403305P | 2005-05-24 | 2005-05-24 | |
| PCT/IB2006/000954 WO2006106427A1 (en) | 2005-04-06 | 2006-03-27 | 7-fluoro-1,3-dihydro-indol-2-one oxazolidinones as antibacterial agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008534672A JP2008534672A (ja) | 2008-08-28 |
| JP2008534672A5 true JP2008534672A5 (enExample) | 2009-05-14 |
Family
ID=36636389
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008504870A Withdrawn JP2008534672A (ja) | 2005-04-06 | 2006-03-27 | 抗菌剤としての７−フルオロ−１，３−ジヒドロ−インドール−２−オンオキサゾリジノン |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US7435751B2 (enExample) |
| EP (1) | EP1869030A1 (enExample) |
| JP (1) | JP2008534672A (enExample) |
| KR (1) | KR20070108938A (enExample) |
| AP (1) | AP2007004172A0 (enExample) |
| AR (1) | AR053839A1 (enExample) |
| AU (1) | AU2006231919A1 (enExample) |
| BR (1) | BRPI0610533A2 (enExample) |
| CA (1) | CA2603899A1 (enExample) |
| CR (1) | CR9417A (enExample) |
| DO (1) | DOP2006000080A (enExample) |
| GT (1) | GT200600133A (enExample) |
| IL (1) | IL186119A0 (enExample) |
| MX (1) | MX2007012386A (enExample) |
| NL (1) | NL1031525C2 (enExample) |
| NO (1) | NO20075505L (enExample) |
| PE (1) | PE20061301A1 (enExample) |
| TN (1) | TNSN07373A1 (enExample) |
| TW (1) | TW200716101A (enExample) |
| UY (1) | UY29452A1 (enExample) |
| WO (1) | WO2006106427A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1781643A1 (en) * | 2004-08-06 | 2007-05-09 | Pharmacia & Upjohn Company LLC | Oxindole oxazolidinones as antibacterial agents |
| KR100891485B1 (ko) | 2007-10-29 | 2009-04-02 | 주식회사 만도 | 디스크 브레이크의 주차브레이크 장치 |
| US20090124737A1 (en) * | 2007-11-12 | 2009-05-14 | Eastman Chemical Company | Acrylic plastisol viscosity reducers |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5164510A (en) | 1988-09-15 | 1992-11-17 | The Upjohn Company | 5'Indolinyl-5β-amidomethyloxazolidin-2-ones |
| ATE112773T1 (de) | 1988-09-15 | 1994-10-15 | Upjohn Co | 5-indolinyl-5-beta-amidomethyloxazolidin-2-one, 3-(substituierte kondensierte)phenyl-5-beta amidomethyloxazolidin-2-one und 3-(nitrogen- substituierte)phenyl-5-beta-amidomethyloxazolid n-2-one. |
| DE4425613A1 (de) | 1994-07-20 | 1996-01-25 | Bayer Ag | 5-gliedrige Heteroaryl-oxazolidinone |
| DE4425612A1 (de) | 1994-07-20 | 1996-04-04 | Bayer Ag | 6-gliedrige stickstoffhaltige Heteroaryl-oxazolidinone |
| US6015429A (en) * | 1994-09-08 | 2000-01-18 | Gore Enterprise Holdings, Inc. | Procedures for introducing stents and stent-grafts |
| DE19604223A1 (de) | 1996-02-06 | 1997-08-07 | Bayer Ag | Neue substituierte Oxazolidinone |
| DE19649095A1 (de) | 1996-02-06 | 1997-08-07 | Bayer Ag | Neue Heteroaryl-Oxazolidinone |
| CN1288462A (zh) | 1998-01-23 | 2001-03-21 | 法玛西雅厄普约翰美国公司 | 噁唑烷酮组合库、组合物和制备方法 |
| CN1301248A (zh) | 1998-04-14 | 2001-06-27 | 三星精密化学株式会社 | 手性(s)－2,3－二取代－1－丙胺衍生物的制备方法 |
| AU1379900A (en) | 1998-11-17 | 2000-06-05 | Bayer Aktiengesellschaft | Novel substituted phenyloxazolidone derivatives |
| AU764980B2 (en) | 1998-11-27 | 2003-09-04 | Pharmacia & Upjohn Company | Oxazolidinone antibacterial agents having a thiocarbonyl functionality |
| JP2003501351A (ja) | 1999-05-27 | 2003-01-14 | ファルマシア・アンド・アップジョン・カンパニー | 抗菌剤としての二環系オキサゾリジノン |
| ATE321024T1 (de) | 2000-10-17 | 2006-04-15 | Pharmacia & Upjohn Co Llc | Verfahren zur herstellung von oxazolidinonverbindungen |
| ES2268011T3 (es) | 2001-04-07 | 2007-03-16 | Astrazeneca Ab | Oxazolidinonas que contienen un grupo sulfonimida como antibioticos. |
| EP1380121B1 (en) | 2001-04-20 | 2007-09-26 | Pharmacia & Upjohn Company LLC | Process to prepare oxazolidinones |
| AR038536A1 (es) | 2002-02-25 | 2005-01-19 | Upjohn Co | N-aril-2-oxazolidinona-5- carboxamidas y sus derivados |
| US7012088B2 (en) * | 2003-02-24 | 2006-03-14 | Pharmacia & Upjohn Company | Indolone oxazolidinones and derivatives thereof |
| EP1781643A1 (en) * | 2004-08-06 | 2007-05-09 | Pharmacia & Upjohn Company LLC | Oxindole oxazolidinones as antibacterial agents |
-
2006
- 2006-03-26 AU AU2006231919A patent/AU2006231919A1/en not_active Abandoned
- 2006-03-27 AP AP2007004172A patent/AP2007004172A0/xx unknown
- 2006-03-27 BR BRPI0610533-5A patent/BRPI0610533A2/pt not_active Application Discontinuation
- 2006-03-27 MX MX2007012386A patent/MX2007012386A/es unknown
- 2006-03-27 CA CA002603899A patent/CA2603899A1/en not_active Abandoned
- 2006-03-27 JP JP2008504870A patent/JP2008534672A/ja not_active Withdrawn
- 2006-03-27 EP EP06727519A patent/EP1869030A1/en not_active Withdrawn
- 2006-03-27 KR KR1020077022657A patent/KR20070108938A/ko not_active Ceased
- 2006-03-27 WO PCT/IB2006/000954 patent/WO2006106427A1/en not_active Ceased
- 2006-03-30 US US11/393,961 patent/US7435751B2/en not_active Expired - Fee Related
- 2006-04-04 TW TW095112018A patent/TW200716101A/zh unknown
- 2006-04-04 PE PE2006000363A patent/PE20061301A1/es not_active Application Discontinuation
- 2006-04-04 UY UY29452A patent/UY29452A1/es not_active Application Discontinuation
- 2006-04-04 AR ARP060101328A patent/AR053839A1/es unknown
- 2006-04-05 GT GT200600133A patent/GT200600133A/es unknown
- 2006-04-05 DO DO2006000080A patent/DOP2006000080A/es unknown
- 2006-04-05 NL NL1031525A patent/NL1031525C2/nl not_active IP Right Cessation
-
2007
- 2007-09-20 IL IL186119A patent/IL186119A0/en unknown
- 2007-10-05 CR CR9417A patent/CR9417A/es unknown
- 2007-10-05 TN TNP2007000373A patent/TNSN07373A1/fr unknown
- 2007-10-31 NO NO20075505A patent/NO20075505L/no not_active Application Discontinuation
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