JP2008530242A5 - - Google Patents

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Publication number
JP2008530242A5
JP2008530242A5 JP2007556366A JP2007556366A JP2008530242A5 JP 2008530242 A5 JP2008530242 A5 JP 2008530242A5 JP 2007556366 A JP2007556366 A JP 2007556366A JP 2007556366 A JP2007556366 A JP 2007556366A JP 2008530242 A5 JP2008530242 A5 JP 2008530242A5
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JP
Japan
Prior art keywords
substituted
unsubstituted
group
alkyl
amino
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JP2007556366A
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English (en)
Japanese (ja)
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JP5134974B2 (ja
JP2008530242A (ja
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Priority claimed from US11/096,718 external-priority patent/US7521465B2/en
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Publication of JP2008530242A publication Critical patent/JP2008530242A/ja
Publication of JP2008530242A5 publication Critical patent/JP2008530242A5/ja
Application granted granted Critical
Publication of JP5134974B2 publication Critical patent/JP5134974B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2007556366A 2005-02-17 2006-02-17 血漿中のグルコースレベル、コレステロールレベル及びトリグリセリドレベルを低下させるための5−[4−(4−(2−アミノ−2−メトキシカルボニルエチル)フェノキシ)ベンジリデン]チアゾリジン−2,4−ジオン誘導体及び関連化合物 Expired - Fee Related JP5134974B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IN347DE2005 2005-02-17
IN347/DEL/2005 2005-02-17
US11/096,718 US7521465B2 (en) 2003-01-17 2005-03-31 Diphenyl ether derivatives
US11/096,718 2005-03-31
PCT/US2006/005846 WO2006089225A1 (en) 2005-02-17 2006-02-17 5- [4- (4- (2 -amino- 2 -methoxycarbonylethyl) phenoxy) benzilidene] thiazolidin-2 , 4-dion e derivatives and related compounds for reducing glucose, cholesterol and triglyceride levels in plasma

Publications (3)

Publication Number Publication Date
JP2008530242A JP2008530242A (ja) 2008-08-07
JP2008530242A5 true JP2008530242A5 (enExample) 2009-04-16
JP5134974B2 JP5134974B2 (ja) 2013-01-30

Family

ID=36570583

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007556366A Expired - Fee Related JP5134974B2 (ja) 2005-02-17 2006-02-17 血漿中のグルコースレベル、コレステロールレベル及びトリグリセリドレベルを低下させるための5−[4−(4−(2−アミノ−2−メトキシカルボニルエチル)フェノキシ)ベンジリデン]チアゾリジン−2,4−ジオン誘導体及び関連化合物

Country Status (9)

Country Link
US (1) US7521465B2 (enExample)
EP (1) EP1848700B1 (enExample)
JP (1) JP5134974B2 (enExample)
KR (1) KR20070105364A (enExample)
CA (1) CA2598087C (enExample)
ES (1) ES2566337T3 (enExample)
HU (1) HUE028882T2 (enExample)
PL (1) PL1848700T3 (enExample)
WO (1) WO2006089225A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9969980B2 (en) * 2001-09-21 2018-05-15 Garnet Biotherapeutics Cell populations which co-express CD49c and CD90
US9969977B2 (en) * 2002-09-20 2018-05-15 Garnet Biotherapeutics Cell populations which co-express CD49c and CD90
US7521465B2 (en) 2003-01-17 2009-04-21 Bexel Pharmaceuticals, Inc. Diphenyl ether derivatives
US7781464B2 (en) 2003-01-17 2010-08-24 Bexel Pharmaceuticals, Inc. Heterocyclic diphenyl ethers
US7087576B2 (en) * 2003-10-07 2006-08-08 Bexel Pharmaceuticals, Inc. Dipeptide phenyl ethers
KR100814109B1 (ko) * 2006-01-09 2008-03-14 한국생명공학연구원 로다닌 유도체, 이의 제조방법 및 이를 유효성분으로함유하는 약학적 조성물
EP2066800A2 (en) * 2006-08-04 2009-06-10 Decode Genetics EHF Aryl amino acid derivatives as inhibitors of lta4h (leukotriene a4 hydrolase) for treating inflammation
US20090069313A1 (en) * 2007-09-06 2009-03-12 Orchid Research Laboratories Ltd. Novel MAO-A inhibitors
CN102036974B (zh) 2008-05-20 2014-07-23 默沙东公司 利用甘露糖基转移酶抑制剂有效生产异源蛋白质
CA2805245A1 (en) * 2010-07-28 2012-02-02 Orchid Research Laboratories Ltd. Diphenyl ether compounds for the treatment of liver, lung disorders, diabetic complications and cardiovascular diseases
JP6014816B2 (ja) 2011-05-10 2016-10-26 国立大学法人神戸大学 Ras機能阻害作用を有するチオキソチアゾリジン誘導体
EP4029859A1 (en) * 2014-11-21 2022-07-20 Bsim Therapeutics, S.A. 2-oxothiazolidin-4-one derivatives active as transthyretin ligands and uses thereof
TW202019923A (zh) * 2018-07-16 2020-06-01 義大利商吉斯藥品公司 作為Rho-激酶抑制劑之酪胺酸醯胺衍生物

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US20020049240A1 (en) 1994-12-19 2002-04-25 Beecham Group P.1.C. Novel compounds
US5166137A (en) 1991-03-27 1992-11-24 Nobipols Forskningsstiftelse Guluronic acid polymers and use of same for inhibition of cytokine production
US5441971A (en) 1991-04-11 1995-08-15 The Upjohn Company Thiazolidinedione derivatives, production and use thereof
TW268952B (enExample) 1993-02-26 1996-01-21 Takeda Pharm Industry Co Ltd
US5527546A (en) 1994-08-10 1996-06-18 Bayer Corporation Human interleukin 6 inhibitor
ES2220929T3 (es) 1995-05-11 2004-12-16 Applied Research Systems Ars Holding N.V. Inhibidor de la actividad il-6.
TW577875B (en) 1997-01-31 2004-03-01 Shionogi & Co Pyrrolidine derivatives with inhibitory activity for phospholipase A2
US6331633B1 (en) 1998-05-08 2001-12-18 Calyx Therapeutics Inc. Heterocyclic analogs of diphenylethylene compounds
US6699896B1 (en) 1998-05-12 2004-03-02 Wyeth Oxazole-aryl-carboxylic acids useful in the treatment of insulin resistance and hyperglycemia
CN1311787A (zh) 1998-06-05 2001-09-05 阿斯特拉曾尼卡有限公司 噁唑烷酮衍生物、其制备方法以及含有它们的药物组合物
AU4713499A (en) 1998-06-27 2000-01-17 Photogenesis, Inc. Ophthalmic uses of ppargamma agonists and ppargamma antagonists
KR100613175B1 (ko) 1998-08-27 2006-08-17 오노 야꾸힝 고교 가부시키가이샤 카르복실산 유도체 및 그 유도체를 유효 성분으로서함유하는 약제
ID30498A (id) 1999-04-07 2001-12-13 Sankyo Co Senyawa-senyawa turunan amina
EP1177187B1 (en) 1999-04-28 2007-07-25 Sanofi-Aventis Deutschland GmbH Di-aryl acid derivatives as ppar receptor ligands
TWI284533B (en) 1999-05-24 2007-08-01 Sankyo Co Pharmaceutical composition for treating hyperglycemia, impaired glucose tolerance, diabetes complications and for improving insulin resistant
CN1321153A (zh) 1999-07-01 2001-11-07 杰龙公司 端粒酶抑制剂及其使用方法
KR100738245B1 (ko) 1999-08-23 2007-07-12 교린 세이야꾸 가부시키 가이샤 치환된 벤질티아졸리딘-2,4-디온 유도체
CA2383347A1 (en) 1999-08-31 2001-03-08 Maxia Pharmaceuticals, Inc. Benzylidene-thiazolidinediones and analogues and their use in the treatment of diabetes
JP2001199888A (ja) 2000-01-24 2001-07-24 Fujimoto Brothers:Kk 糖尿病治療剤
JP2001308814A (ja) 2000-04-19 2001-11-02 Hitachi Ltd フレーム構成自動識別通信装置
ES2248242T3 (es) 2000-04-21 2006-03-16 Pfizer Products Inc. Ligandos de receptores tiroideos.
US6620830B2 (en) 2000-04-21 2003-09-16 Pfizer, Inc. Thyroid receptor ligands
US6680387B2 (en) 2000-04-24 2004-01-20 Aryx Therapeutics Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
US6525202B2 (en) * 2000-07-17 2003-02-25 Wyeth Cyclic amine phenyl beta-3 adrenergic receptor agonists
HUP0401492A3 (en) 2001-09-14 2008-05-28 Novo Nordisk As Novel ligands for the hisb10 zn2+ sites of r-state insulin hexa
JP2005513026A (ja) * 2001-11-15 2005-05-12 インサイト サン ディエゴ インコーポレイテッド 高コレステロール血症、異脂肪血症および他の代謝障害;癌、および他の疾患を治療するn−置換複素環
US7521465B2 (en) 2003-01-17 2009-04-21 Bexel Pharmaceuticals, Inc. Diphenyl ether derivatives
US6794401B2 (en) 2003-01-17 2004-09-21 Bexel Pharmaceuticals, Inc. Amino acid phenoxy ethers
EP1610812A1 (en) 2003-03-11 2006-01-04 Novo Nordisk A/S Pharmaceutical preparations comprising acid-stabilised insulin
US7087576B2 (en) 2003-10-07 2006-08-08 Bexel Pharmaceuticals, Inc. Dipeptide phenyl ethers

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