JP2008523146A5 - - Google Patents
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- Publication number
- JP2008523146A5 JP2008523146A5 JP2007546799A JP2007546799A JP2008523146A5 JP 2008523146 A5 JP2008523146 A5 JP 2008523146A5 JP 2007546799 A JP2007546799 A JP 2007546799A JP 2007546799 A JP2007546799 A JP 2007546799A JP 2008523146 A5 JP2008523146 A5 JP 2008523146A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- optionally substituted
- agonist
- disorder
- disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000000203 mixture Substances 0.000 claims 14
- 239000000556 agonist Substances 0.000 claims 8
- 208000015122 neurodegenerative disease Diseases 0.000 claims 6
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 5
- 208000035475 disorder Diseases 0.000 claims 5
- 125000001072 heteroaryl group Chemical group 0.000 claims 5
- 125000003118 aryl group Chemical group 0.000 claims 4
- 150000001875 compounds Chemical class 0.000 claims 4
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 claims 3
- 125000005842 heteroatom Chemical group 0.000 claims 3
- 229910052760 oxygen Inorganic materials 0.000 claims 3
- 229910052717 sulfur Inorganic materials 0.000 claims 3
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 claims 2
- 208000024827 Alzheimer disease Diseases 0.000 claims 2
- 206010003497 Asphyxia Diseases 0.000 claims 2
- 125000003601 C2-C6 alkynyl group Chemical group 0.000 claims 2
- 206010019196 Head injury Diseases 0.000 claims 2
- 208000023105 Huntington disease Diseases 0.000 claims 2
- 208000018737 Parkinson disease Diseases 0.000 claims 2
- -1 [1,3] thiazol-5-yl Chemical group 0.000 claims 2
- 206010002026 amyotrophic lateral sclerosis Diseases 0.000 claims 2
- 125000004429 atom Chemical group 0.000 claims 2
- 125000002619 bicyclic group Chemical group 0.000 claims 2
- 125000004122 cyclic group Chemical group 0.000 claims 2
- 206010015037 epilepsy Diseases 0.000 claims 2
- 229910052736 halogen Inorganic materials 0.000 claims 2
- 150000002367 halogens Chemical class 0.000 claims 2
- 208000014674 injury Diseases 0.000 claims 2
- 229910052757 nitrogen Inorganic materials 0.000 claims 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- QZAYGJVTTNCVMB-UHFFFAOYSA-N serotonin Chemical compound C1=C(O)C=C2C(CCN)=CNC2=C1 QZAYGJVTTNCVMB-UHFFFAOYSA-N 0.000 claims 2
- 230000008733 trauma Effects 0.000 claims 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 claims 1
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 claims 1
- SFSFIDVAEMDPIP-UHFFFAOYSA-N 2-[3-(3-fluorophenyl)sulfonylpyrrolo[2,3-b]pyridin-1-yl]-n,n-dimethylethanamine Chemical compound C12=CC=CN=C2N(CCN(C)C)C=C1S(=O)(=O)C1=CC=CC(F)=C1 SFSFIDVAEMDPIP-UHFFFAOYSA-N 0.000 claims 1
- 208000030507 AIDS Diseases 0.000 claims 1
- 206010012289 Dementia Diseases 0.000 claims 1
- 208000017442 Retinal disease Diseases 0.000 claims 1
- 230000001154 acute effect Effects 0.000 claims 1
- 150000001412 amines Chemical class 0.000 claims 1
- 230000001684 chronic effect Effects 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 1
- UFBBWLWUIISIPW-UHFFFAOYSA-N imidazo[2,1-b][1,3]thiazole Chemical compound C1=CSC2=NC=CN21 UFBBWLWUIISIPW-UHFFFAOYSA-N 0.000 claims 1
- 125000004433 nitrogen atom Chemical group N* 0.000 claims 1
- 125000003170 phenylsulfonyl group Chemical group C1(=CC=CC=C1)S(=O)(=O)* 0.000 claims 1
- 125000003107 substituted aryl group Chemical group 0.000 claims 1
- 125000000472 sulfonyl group Chemical group *S(*)(=O)=O 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63576604P | 2004-12-14 | 2004-12-14 | |
| PCT/US2005/044820 WO2006065710A1 (en) | 2004-12-14 | 2005-12-12 | Use of a 5-ht6 agonist for the treatment and prevention of neurodegenerative disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008523146A JP2008523146A (ja) | 2008-07-03 |
| JP2008523146A5 true JP2008523146A5 (enExample) | 2009-01-22 |
Family
ID=36177731
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007546799A Withdrawn JP2008523146A (ja) | 2004-12-14 | 2005-12-12 | 神経変性障害の処置および予防のための５−ｈｔ６アゴニストの使用 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20060128744A1 (enExample) |
| EP (1) | EP1824464A1 (enExample) |
| JP (1) | JP2008523146A (enExample) |
| KR (1) | KR20070088770A (enExample) |
| CN (1) | CN101098683A (enExample) |
| AU (1) | AU2005316675A1 (enExample) |
| BR (1) | BRPI0519036A2 (enExample) |
| CA (1) | CA2590841A1 (enExample) |
| CR (1) | CR9200A (enExample) |
| IL (1) | IL183859A0 (enExample) |
| MX (1) | MX2007007206A (enExample) |
| NO (1) | NO20073104L (enExample) |
| RU (1) | RU2007122450A (enExample) |
| WO (1) | WO2006065710A1 (enExample) |
| ZA (1) | ZA200705083B (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200301251A (en) * | 2001-12-20 | 2003-07-01 | Wyeth Corp | Azaindolylalkylamine derivatives as 5-hydroxytryptamine-6 ligands |
| JP2005305107A (ja) * | 2004-03-25 | 2005-11-04 | Sei Matsuoka | 価値的情報値の測定装置およびこれを使用した測定方法 |
| JP5682051B2 (ja) | 2006-05-18 | 2015-03-11 | ファーマサイクリックス，インク． | 細胞内キナーゼ阻害剤 |
| EP1953153A1 (en) * | 2007-01-31 | 2008-08-06 | Laboratorios del Dr. Esteve S.A. | Heterocyclyl-substituted sulfonamides for the treatment of cognitive or food ingestion related disorders |
| US8252821B2 (en) * | 2009-04-14 | 2012-08-28 | Bristol-Myers Squibb Company | Bioavailable capsule compositions of amorphous alpha-(N-sulfonamido)acetamide compound |
| CN104276993B (zh) * | 2013-07-12 | 2019-03-15 | 广东东阳光药业有限公司 | 吲哚衍生物及其在药物上的应用 |
| CN104557664B (zh) * | 2013-10-19 | 2020-01-21 | 广东东阳光药业有限公司 | 芳杂环类衍生物及其在药物上的应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9820113D0 (en) * | 1998-09-15 | 1998-11-11 | Merck Sharp & Dohme | Therapeutic agents |
| JP4335684B2 (ja) * | 2001-12-20 | 2009-09-30 | ワイス | ５−ヒドロキシトリプタミン−６リガンドとしてのインドリルアルキルアミン誘導体 |
| UA78999C2 (en) * | 2002-06-04 | 2007-05-10 | Wyeth Corp | 1-(aminoalkyl)-3-sulfonylazaindoles as ligands of 5-hydroxytryptamine-6 |
-
2005
- 2005-12-12 CN CNA2005800464202A patent/CN101098683A/zh not_active Withdrawn
- 2005-12-12 RU RU2007122450/14A patent/RU2007122450A/ru not_active Application Discontinuation
- 2005-12-12 WO PCT/US2005/044820 patent/WO2006065710A1/en not_active Ceased
- 2005-12-12 CA CA002590841A patent/CA2590841A1/en not_active Abandoned
- 2005-12-12 JP JP2007546799A patent/JP2008523146A/ja not_active Withdrawn
- 2005-12-12 BR BRPI0519036-3A patent/BRPI0519036A2/pt not_active IP Right Cessation
- 2005-12-12 EP EP05853687A patent/EP1824464A1/en not_active Withdrawn
- 2005-12-12 AU AU2005316675A patent/AU2005316675A1/en not_active Abandoned
- 2005-12-12 MX MX2007007206A patent/MX2007007206A/es unknown
- 2005-12-12 KR KR1020077015556A patent/KR20070088770A/ko not_active Withdrawn
- 2005-12-13 US US11/301,445 patent/US20060128744A1/en not_active Abandoned
-
2007
- 2007-06-12 IL IL183859A patent/IL183859A0/en unknown
- 2007-06-13 ZA ZA200705083A patent/ZA200705083B/xx unknown
- 2007-06-18 NO NO20073104A patent/NO20073104L/no not_active Application Discontinuation
- 2007-06-20 CR CR9200A patent/CR9200A/es not_active Application Discontinuation
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