JP2010513434A5 - - Google Patents

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Publication number
JP2010513434A5
JP2010513434A5 JP2009542194A JP2009542194A JP2010513434A5 JP 2010513434 A5 JP2010513434 A5 JP 2010513434A5 JP 2009542194 A JP2009542194 A JP 2009542194A JP 2009542194 A JP2009542194 A JP 2009542194A JP 2010513434 A5 JP2010513434 A5 JP 2010513434A5
Authority
JP
Japan
Prior art keywords
oxy
azoniabicyclo
octane
alkyl
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2009542194A
Other languages
English (en)
Japanese (ja)
Other versions
JP2010513434A (ja
JP4604129B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/GB2007/004817 external-priority patent/WO2008075005A1/en
Publication of JP2010513434A publication Critical patent/JP2010513434A/ja
Publication of JP2010513434A5 publication Critical patent/JP2010513434A5/ja
Application granted granted Critical
Publication of JP4604129B2 publication Critical patent/JP4604129B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2009542194A 2006-12-19 2007-12-17 ムスカリン受容体アンタゴニストとしてのキヌクリジノール誘導体 Expired - Fee Related JP4604129B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US87063806P 2006-12-19 2006-12-19
PCT/GB2007/004817 WO2008075005A1 (en) 2006-12-19 2007-12-17 Quinuclidinol derivatives as muscarinic receptor antagonists

Publications (3)

Publication Number Publication Date
JP2010513434A JP2010513434A (ja) 2010-04-30
JP2010513434A5 true JP2010513434A5 (enExample) 2010-06-17
JP4604129B2 JP4604129B2 (ja) 2010-12-22

Family

ID=39166793

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009542194A Expired - Fee Related JP4604129B2 (ja) 2006-12-19 2007-12-17 ムスカリン受容体アンタゴニストとしてのキヌクリジノール誘導体

Country Status (22)

Country Link
US (1) US20100113510A1 (enExample)
EP (1) EP2121137B1 (enExample)
JP (1) JP4604129B2 (enExample)
KR (1) KR20090094460A (enExample)
CN (1) CN101610813A (enExample)
AR (1) AR064414A1 (enExample)
AT (1) ATE555111T1 (enExample)
AU (1) AU2007336054A1 (enExample)
BR (1) BRPI0721039A2 (enExample)
CA (1) CA2672446A1 (enExample)
CL (1) CL2007003690A1 (enExample)
CO (1) CO6180439A2 (enExample)
EC (1) ECSP099394A (enExample)
ES (1) ES2385681T3 (enExample)
IL (1) IL199015A0 (enExample)
MX (1) MX2009006018A (enExample)
NO (1) NO20092689L (enExample)
PE (1) PE20081837A1 (enExample)
RU (1) RU2009120229A (enExample)
TW (1) TW200831507A (enExample)
UY (1) UY30803A1 (enExample)
WO (1) WO2008075005A1 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200825084A (en) 2006-11-14 2008-06-16 Astrazeneca Ab New compounds 521
GB0808707D0 (en) * 2008-05-13 2008-06-18 Argenta Discovery Ltd New compounds 275
EA017627B1 (ru) 2008-05-13 2013-01-30 Астразенека Аб Хинуклидиновые производные в качестве антагонистов мускаринового м3 рецептора
WO2009153536A1 (en) * 2008-06-17 2009-12-23 Argenta Discovery Limited 1-aza-bicyclo [2.2.2] octane derivatives useful as muscarinic receptor antagonists
GB0811100D0 (en) * 2008-06-17 2008-07-23 Astrazeneca Ab New combination
GB0811099D0 (en) * 2008-06-17 2008-07-23 Astrazeneca Ab New combination 376
WO2010008341A1 (en) * 2008-07-16 2010-01-21 Astrazeneca Ab A combination of (a) glucocorticoid receptor modulator and (b) a muscarinic antagonist
EP2206712A1 (en) * 2008-12-23 2010-07-14 CHIESI FARMACEUTICI S.p.A. "Alkaloid aminoester derivatives and medicinal composition thereof"
TW201036957A (en) 2009-02-20 2010-10-16 Astrazeneca Ab Novel salt 628
WO2010144043A1 (en) * 2009-06-12 2010-12-16 Astrazeneca Ab A novel 4-methylbenzenesulphonate salt and a process for preparing a pharmaceutical composition comprising the salt
US20120220590A1 (en) 2009-07-31 2012-08-30 Thombare Pravin S Novel compounds as modulators of glucocorticoid receptors
WO2011073662A1 (en) 2009-12-17 2011-06-23 Astrazeneca Ab Combination of a benzoxazinone and a further agent for treating respiratory diseases
BR112012031967A2 (pt) 2010-06-22 2019-09-24 Chiesi Farm Spa composto, uso de um composto, combinação de um composto e composição farmacêutica
EP2585457B1 (en) * 2010-06-22 2015-07-22 Chiesi Farmaceutici S.p.A. Alkaloid aminoester derivatives and medicinal composition thereof
BR112014013179A2 (pt) 2011-12-30 2017-06-13 Chiesi Farm Spa compostos, combinação de um composto, composição farmacêutica e usos de um composto
JP6218940B2 (ja) * 2013-07-13 2017-10-25 ベイジン エフエスウェルカム テクノロジー ディベロップメント カンパニー リミテッド キニン系化合物、その光学異性体及びその製造方法と医薬用途

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8334494D0 (en) 1983-12-24 1984-02-01 Tanabe Seiyaku Co Carbostyril derivatives
GB8923590D0 (en) * 1989-10-19 1989-12-06 Pfizer Ltd Antimuscarinic bronchodilators
GR1001529B (el) 1990-09-07 1994-03-31 Elmuquimica Farm Sl Μέ?οδος για την λήψη νέων 21-εστέρων της 16-17-ακετάλης της πρ να-1,4-διενο-3,20-διόνης.
GB9624482D0 (en) 1995-12-18 1997-01-15 Zeneca Phaema S A Chemical compounds
DE69720965T2 (de) 1996-02-13 2004-02-05 Astrazeneca Ab Chinazolinderivate und deren verwendung als vegf hemmer
NZ331191A (en) 1996-03-05 2000-03-27 Zeneca Ltd 4-anilinoquinazoline derivatives and pharmaceutical compositions thereof
GB9718972D0 (en) 1996-09-25 1997-11-12 Zeneca Ltd Chemical compounds
GB9714249D0 (en) 1997-07-08 1997-09-10 Angiogene Pharm Ltd Vascular damaging agents
GB9900334D0 (en) 1999-01-07 1999-02-24 Angiogene Pharm Ltd Tricylic vascular damaging agents
GB9900752D0 (en) 1999-01-15 1999-03-03 Angiogene Pharm Ltd Benzimidazole vascular damaging agents
AU2001258628A1 (en) 2000-05-31 2001-12-11 Astrazeneca Ab Indole derivatives with vascular damaging activity
GB0015876D0 (en) 2000-06-28 2000-08-23 Novartis Ag Organic compounds
MXPA02012905A (es) 2000-07-07 2004-07-30 Angiogene Pharm Ltd Derivados de colquinol como agentes de dano vascular..
MXPA02012903A (es) 2000-07-07 2004-07-30 Angiogene Pharm Ltd Derivados de colquinol como inhibidores de angiogenesis.
ES2296923T3 (es) 2001-03-22 2008-05-01 Glaxo Group Limited Derivados formanilidas como agonistas del adrenorreceptor beta2.
KR100831534B1 (ko) 2001-04-30 2008-05-22 글락소 그룹 리미티드 17.알파 위치에 시클릭 에스테르기를 지닌 항염증성의안드로스탄의 17.베타.-카르보티오에이트 에스테르 유도체
US20030229058A1 (en) 2001-11-13 2003-12-11 Moran Edmund J. Aryl aniline beta2 adrenergic receptor agonists
TWI249515B (en) 2001-11-13 2006-02-21 Theravance Inc Aryl aniline beta2 adrenergic receptor agonists
ES2302938T3 (es) 2002-10-11 2008-08-01 Pfizer Inc. Derivados de indol como agonistas beta-2.
US7056916B2 (en) 2002-11-15 2006-06-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Medicaments for the treatment of chronic obstructive pulmonary disease
AR044134A1 (es) * 2003-05-02 2005-08-24 Novartis Ag Derivados de quinuclidina, metodo de preparacion y composiciones farmaceuticas.
CN100445281C (zh) * 2003-05-02 2008-12-24 诺瓦提斯公司 与毒蕈碱性m3受体结合的奎宁环衍生物
US20090246281A1 (en) 2003-11-03 2009-10-01 Norton Healthcare Ltd. Soft steroid compositions for use in dry powder inhalers
US20090093485A1 (en) 2004-10-29 2009-04-09 Astrazeneca Ab Novel Sulphonamide Derivatives as Glucocorticoid Receptor Modulators for the Treatment of Inflammatory Diseases
GB0424284D0 (en) * 2004-11-02 2004-12-01 Novartis Ag Organic compounds
TW200722418A (en) * 2005-04-20 2007-06-16 Astrazeneca Ab Novel compounds

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