JP2008511669A5 - - Google Patents

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Publication number
JP2008511669A5
JP2008511669A5 JP2007530353A JP2007530353A JP2008511669A5 JP 2008511669 A5 JP2008511669 A5 JP 2008511669A5 JP 2007530353 A JP2007530353 A JP 2007530353A JP 2007530353 A JP2007530353 A JP 2007530353A JP 2008511669 A5 JP2008511669 A5 JP 2008511669A5
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JP
Japan
Prior art keywords
methyl
het
cycloalkyl
alkyl
independently
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2007530353A
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English (en)
Japanese (ja)
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JP2008511669A (ja
JP2008511669A6 (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2005/031099 external-priority patent/WO2006026703A2/en
Publication of JP2008511669A publication Critical patent/JP2008511669A/ja
Publication of JP2008511669A6 publication Critical patent/JP2008511669A6/ja
Publication of JP2008511669A5 publication Critical patent/JP2008511669A5/ja
Pending legal-status Critical Current

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JP2007530353A 2004-09-02 2005-08-28 化合物 Pending JP2008511669A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US60674204P 2004-09-02 2004-09-02
US60/606,742 2004-09-02
US61076504P 2004-09-17 2004-09-17
US60/610,765 2004-09-17
PCT/US2005/031099 WO2006026703A2 (en) 2004-09-02 2005-08-28 Chemical compounds

Publications (3)

Publication Number Publication Date
JP2008511669A JP2008511669A (ja) 2008-04-17
JP2008511669A6 JP2008511669A6 (ja) 2008-07-31
JP2008511669A5 true JP2008511669A5 (enExample) 2008-10-16

Family

ID=36000724

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2007530353A Pending JP2008511669A (ja) 2004-09-02 2005-08-28 化合物
JP2007530352A Pending JP2008511668A (ja) 2004-09-02 2005-08-31 化合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2007530352A Pending JP2008511668A (ja) 2004-09-02 2005-08-31 化合物

Country Status (16)

Country Link
US (2) US20070232615A1 (enExample)
EP (2) EP1799671A4 (enExample)
JP (2) JP2008511669A (enExample)
KR (2) KR20070053313A (enExample)
AR (2) AR050302A1 (enExample)
AU (2) AU2005282753A1 (enExample)
BR (1) BRPI0514881A (enExample)
CA (2) CA2579059A1 (enExample)
IL (1) IL181419A0 (enExample)
MA (1) MA28872B1 (enExample)
MX (2) MX2007002679A (enExample)
NO (2) NO20071366L (enExample)
PE (2) PE20060656A1 (enExample)
RU (2) RU2352567C2 (enExample)
TW (2) TW200612921A (enExample)
WO (2) WO2006026703A2 (enExample)

Families Citing this family (28)

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Publication number Priority date Publication date Assignee Title
MX2007002679A (es) * 2004-09-02 2007-05-16 Smithkline Beecham Corp Compuestos quimicos.
PE20070946A1 (es) * 2006-01-25 2007-10-16 Smithkline Beecham Corp COMPUESTOS DERIVADOS DE IMIDAZO[1,2-a]PIRIDINA COMO MODULADORES DEL RECEPTOR DE QUIMIOQUINA (CXCR4)
US8618122B2 (en) 2006-05-16 2013-12-31 Ono Pharmaceutical Co., Ltd. Compound having acidic group which may be protected, and use thereof
WO2008016006A1 (fr) 2006-07-31 2008-02-07 Ono Pharmaceutical Co., Ltd. Composé auquel un groupe cyclique est lié par une liaison spiro et son utilisation
US7767826B2 (en) * 2007-10-05 2010-08-03 Pharmatech International, Inc. Process for the synthesis of L-(+)-ergothioneine
CA2704645A1 (en) * 2007-11-09 2009-05-14 The Salk Institute For Biological Studies Non-nucleoside reverse transcriptase inhibitors
CN102675305B (zh) * 2011-03-08 2014-11-12 中国科学院上海药物研究所 一类咪唑并吡啶类化合物及其制备方法和用途
CN103570683B (zh) * 2012-07-30 2018-04-17 中国科学院上海药物研究所 多取代胺类化合物及其制备方法和用途
TWI720451B (zh) 2014-02-13 2021-03-01 美商英塞特控股公司 作為lsd1抑制劑之環丙胺
US9670210B2 (en) 2014-02-13 2017-06-06 Incyte Corporation Cyclopropylamines as LSD1 inhibitors
WO2016007722A1 (en) 2014-07-10 2016-01-14 Incyte Corporation Triazolopyridines and triazolopyrazines as lsd1 inhibitors
MX373154B (es) * 2015-04-03 2020-04-22 Incyte Holdings Corp Compuestos heterocíclicos como inhibidores de demetilasa 1 específica de lisina (lsd1).
LT3334709T (lt) 2015-08-12 2025-03-10 Incyte Holdings Corporation Lsd1 inhibitoriaus druskos
JP6864296B2 (ja) 2015-12-14 2021-04-28 エックス4 ファーマシューティカルズ, インコーポレイテッド がんを処置する方法
WO2017106332A1 (en) 2015-12-14 2017-06-22 X4 Pharmaceuticals, Inc. Methods for treating cancer
JP6856648B2 (ja) * 2015-12-15 2021-04-07 ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company Cxcr4受容体アンタゴニスト
PL3393468T3 (pl) 2015-12-22 2023-01-23 X4 Pharmaceuticals, Inc. Metody leczenia niedoboru odporności
CA3019394A1 (en) 2016-04-08 2017-10-12 X4 Pharmaceuticals, Inc. Methods for treating cancer
JP6994767B2 (ja) * 2016-06-21 2022-01-14 エックス4 ファーマシューティカルズ, インコーポレイテッド Cxcr4阻害剤およびその使用
JP7084624B2 (ja) 2016-06-21 2022-06-15 エックス4 ファーマシューティカルズ, インコーポレイテッド Cxcr4阻害剤およびその使用
ES2870920T3 (es) 2016-06-21 2021-10-28 X4 Pharmaceuticals Inc Inhibidores de CXCR4 y usos de los mismos
IL309069A (en) 2017-02-21 2024-02-01 Univ Emory CXCR4 cytokine receptor modulators and related uses
JP7282786B2 (ja) * 2017-09-25 2023-05-29 シージーンテック (スーチョウ, チャイナ) カンパニー リミテッド Cxcr4阻害剤としてのヘテロアリール化合物、それを用いた組成物及び方法
KR102678977B1 (ko) * 2017-09-25 2024-06-28 씨젠테크 (쑤저우, 차이나) 컴퍼니 리미티드 Cxcr4 저해제로서 헤테로아릴 화합물, 그 조성물 및 이용 방법
EP3768256A4 (en) 2018-03-19 2021-11-24 Emory University PANTROPIC ENTRY INHIBITORS
US10548889B1 (en) 2018-08-31 2020-02-04 X4 Pharmaceuticals, Inc. Compositions of CXCR4 inhibitors and methods of preparation and use
US10968200B2 (en) 2018-08-31 2021-04-06 Incyte Corporation Salts of an LSD1 inhibitor and processes for preparing the same
CA3171250A1 (en) 2020-03-10 2021-09-16 E. Lynne KELLEY Methods for treating neutropenia

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ225152A (en) * 1987-07-17 1990-04-26 Janssen Pharmaceutica Nv Heterocyclically substituted piperidinyl benzamides as pharmaceuticals
JP2004512336A (ja) * 2000-09-15 2004-04-22 アノーメッド インコーポレイティド ケモカインレセプター結合複素環式化合物
KR20030034184A (ko) * 2000-09-15 2003-05-01 아노르메드 인코포레이티드 케모킨 수용체 결합 헤테로사이클릭 화합물
IL154227A0 (en) * 2000-09-15 2003-07-31 Anormed Inc Chemokine receptor binding heterocyclic compounds
AU9355101A (en) * 2000-09-15 2002-03-26 Anormed Inc Chemokine receptor binding heterocyclic compounds
RU2325387C2 (ru) * 2001-12-21 2008-05-27 Анормед Инк. Гетероциклические соединения с повышенной эффективностью, связывающиеся с рецептором хемокина
CA2520259A1 (en) * 2003-04-11 2004-10-28 Anormed Inc. Cxcr4 chemokine receptor binding compounds
MX2007002679A (es) * 2004-09-02 2007-05-16 Smithkline Beecham Corp Compuestos quimicos.
WO2006036816A2 (en) * 2004-09-24 2006-04-06 Smithkline Beecham Corporation Chemical compounds
EP1919872A4 (en) * 2005-08-31 2009-08-05 Smithkline Beecham Corp CHEMICAL COMPOUNDS

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