JP2008511669A5 - - Google Patents

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Publication number
JP2008511669A5
JP2008511669A5 JP2007530353A JP2007530353A JP2008511669A5 JP 2008511669 A5 JP2008511669 A5 JP 2008511669A5 JP 2007530353 A JP2007530353 A JP 2007530353A JP 2007530353 A JP2007530353 A JP 2007530353A JP 2008511669 A5 JP2008511669 A5 JP 2008511669A5
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JP
Japan
Prior art keywords
methyl
het
cycloalkyl
alkyl
independently
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2007530353A
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English (en)
Japanese (ja)
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JP2008511669A6 (ja
JP2008511669A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2005/031099 external-priority patent/WO2006026703A2/en
Publication of JP2008511669A publication Critical patent/JP2008511669A/ja
Publication of JP2008511669A6 publication Critical patent/JP2008511669A6/ja
Publication of JP2008511669A5 publication Critical patent/JP2008511669A5/ja
Pending legal-status Critical Current

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JP2007530353A 2004-09-02 2005-08-28 化合物 Pending JP2008511669A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US60674204P 2004-09-02 2004-09-02
US60/606,742 2004-09-02
US61076504P 2004-09-17 2004-09-17
US60/610,765 2004-09-17
PCT/US2005/031099 WO2006026703A2 (en) 2004-09-02 2005-08-28 Chemical compounds

Publications (3)

Publication Number Publication Date
JP2008511669A JP2008511669A (ja) 2008-04-17
JP2008511669A6 JP2008511669A6 (ja) 2008-07-31
JP2008511669A5 true JP2008511669A5 (enExample) 2008-10-16

Family

ID=36000724

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2007530353A Pending JP2008511669A (ja) 2004-09-02 2005-08-28 化合物
JP2007530352A Pending JP2008511668A (ja) 2004-09-02 2005-08-31 化合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2007530352A Pending JP2008511668A (ja) 2004-09-02 2005-08-31 化合物

Country Status (16)

Country Link
US (2) US20070232615A1 (enExample)
EP (2) EP1799671A4 (enExample)
JP (2) JP2008511669A (enExample)
KR (2) KR20070049682A (enExample)
AR (2) AR050302A1 (enExample)
AU (2) AU2005279835A1 (enExample)
BR (1) BRPI0514881A (enExample)
CA (2) CA2579059A1 (enExample)
IL (1) IL181419A0 (enExample)
MA (1) MA28872B1 (enExample)
MX (2) MX2007002679A (enExample)
NO (2) NO20071366L (enExample)
PE (2) PE20060712A1 (enExample)
RU (2) RU2352567C2 (enExample)
TW (2) TW200621754A (enExample)
WO (2) WO2006026703A2 (enExample)

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Publication number Priority date Publication date Assignee Title
EP1799671A4 (en) * 2004-09-02 2009-06-10 Smithkline Beecham Corp CHEMICAL COMPOUNDS
AR059197A1 (es) * 2006-01-25 2008-03-19 Smithkline Beecham Corp Derivados de indazolo piridina para el tratamiento de hiv
US8618122B2 (en) 2006-05-16 2013-12-31 Ono Pharmaceutical Co., Ltd. Compound having acidic group which may be protected, and use thereof
WO2008016006A1 (fr) 2006-07-31 2008-02-07 Ono Pharmaceutical Co., Ltd. Composé auquel un groupe cyclique est lié par une liaison spiro et son utilisation
US7767826B2 (en) * 2007-10-05 2010-08-03 Pharmatech International, Inc. Process for the synthesis of L-(+)-ergothioneine
CA2704645A1 (en) * 2007-11-09 2009-05-14 The Salk Institute For Biological Studies Non-nucleoside reverse transcriptase inhibitors
CN102675305B (zh) * 2011-03-08 2014-11-12 中国科学院上海药物研究所 一类咪唑并吡啶类化合物及其制备方法和用途
CN103570683B (zh) * 2012-07-30 2018-04-17 中国科学院上海药物研究所 多取代胺类化合物及其制备方法和用途
WO2015123424A1 (en) 2014-02-13 2015-08-20 Incyte Corporation Cyclopropylamines as lsd1 inhibitors
LT3105218T (lt) 2014-02-13 2019-12-10 Incyte Corp Ciklopropilaminai kaip lsd1 inhibitoriai
WO2016007722A1 (en) 2014-07-10 2016-01-14 Incyte Corporation Triazolopyridines and triazolopyrazines as lsd1 inhibitors
EA201792205A1 (ru) 2015-04-03 2018-02-28 Инсайт Корпорейшн Гетероциклические соединения как ингибиторы lsd1
DK3334709T3 (da) 2015-08-12 2025-02-03 Incyte Holdings Corp Salte af en lsd1-hæmmer
CN109069426B (zh) 2015-12-14 2021-10-29 X4 制药有限公司 治疗癌症的方法
CN109069486A (zh) 2015-12-14 2018-12-21 X4 制药有限公司 治疗癌症的方法
US10450318B2 (en) * 2015-12-15 2019-10-22 Bristol-Myers Squibb Company CXCR4 receptor antagonists
US10610527B2 (en) 2015-12-22 2020-04-07 X4 Pharmaceuticals, Inc. Methods for treating immunodeficiency disease
US11337969B2 (en) 2016-04-08 2022-05-24 X4 Pharmaceuticals, Inc. Methods for treating cancer
EP3808748B1 (en) 2016-06-21 2026-05-20 X4 Pharmaceuticals, Inc. Substituted piperidines as cxcr4-inhibitors
JP6994767B2 (ja) * 2016-06-21 2022-01-14 エックス４ ファーマシューティカルズ， インコーポレイテッド Ｃｘｃｒ４阻害剤およびその使用
US10988465B2 (en) 2016-06-21 2021-04-27 X4 Pharmaceuticals, Inc. CXCR4 inhibitors and uses thereof
US11497744B2 (en) 2017-02-21 2022-11-15 Emory University Chemokine CXCR4 receptor modulators and uses related thereto
KR102678977B1 (ko) * 2017-09-25 2024-06-28 씨젠테크 (쑤저우, 차이나) 컴퍼니 리미티드 Cxcr4 저해제로서 헤테로아릴 화합물, 그 조성물 및 이용 방법
US11396501B2 (en) * 2017-09-25 2022-07-26 Cgenetech (Suzhou, China) Co., Ltd. Heteroaryl compounds as CXCR4 inhibitors, composition and method using the same
EP3768256A4 (en) 2018-03-19 2021-11-24 Emory University PAN-TROPICAL ENTRANCE INHIBITORS
US10968200B2 (en) 2018-08-31 2021-04-06 Incyte Corporation Salts of an LSD1 inhibitor and processes for preparing the same
US10548889B1 (en) 2018-08-31 2020-02-04 X4 Pharmaceuticals, Inc. Compositions of CXCR4 inhibitors and methods of preparation and use
CN115515585A (zh) 2020-03-10 2022-12-23 X4 制药有限公司 用于治疗中性粒细胞减少症的方法
WO2023003862A1 (en) 2021-07-19 2023-01-26 Emory University Cxcr4 modulators and uses related thereto

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ225152A (en) * 1987-07-17 1990-04-26 Janssen Pharmaceutica Nv Heterocyclically substituted piperidinyl benzamides as pharmaceuticals
NZ524421A (en) * 2000-09-15 2005-02-25 Anormed Inc Chemokine receptor binding heterocyclic compounds
JP2004512336A (ja) * 2000-09-15 2004-04-22 アノーメッド　インコーポレイティド ケモカインレセプター結合複素環式化合物
RU2289581C2 (ru) * 2000-09-15 2006-12-20 Анормед, Инк. Гетероциклические соединения, содержащая их фармацевтическая композиция и их применение
KR20030034184A (ko) * 2000-09-15 2003-05-01 아노르메드 인코포레이티드 케모킨 수용체 결합 헤테로사이클릭 화합물
CA2467718C (en) * 2001-12-21 2011-04-26 Anormed Inc. Chemokine receptor binding heterocyclic compounds with enhanced efficacy
CA2520259A1 (en) * 2003-04-11 2004-10-28 Anormed Inc. Cxcr4 chemokine receptor binding compounds
EP1799671A4 (en) * 2004-09-02 2009-06-10 Smithkline Beecham Corp CHEMICAL COMPOUNDS
WO2006036816A2 (en) * 2004-09-24 2006-04-06 Smithkline Beecham Corporation Chemical compounds
US20080234318A1 (en) * 2005-08-31 2008-09-25 Kristjan Gudmundsson Chemical Compounds

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