JP2008510789A5 - - Google Patents
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- Publication number
- JP2008510789A5 JP2008510789A5 JP2007529032A JP2007529032A JP2008510789A5 JP 2008510789 A5 JP2008510789 A5 JP 2008510789A5 JP 2007529032 A JP2007529032 A JP 2007529032A JP 2007529032 A JP2007529032 A JP 2007529032A JP 2008510789 A5 JP2008510789 A5 JP 2008510789A5
- Authority
- JP
- Japan
- Prior art keywords
- compound according
- ring
- dysmenorrhea
- primary
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 150000001875 compounds Chemical class 0.000 claims 8
- 208000005171 Dysmenorrhea Diseases 0.000 claims 4
- 206010013935 Dysmenorrhoea Diseases 0.000 claims 4
- 239000003814 drug Substances 0.000 claims 3
- 206010002383 Angina Pectoris Diseases 0.000 claims 2
- 208000019901 Anxiety disease Diseases 0.000 claims 2
- 201000001320 Atherosclerosis Diseases 0.000 claims 2
- 208000024172 Cardiovascular disease Diseases 0.000 claims 2
- 201000009273 Endometriosis Diseases 0.000 claims 2
- 208000001362 Fetal Growth Retardation Diseases 0.000 claims 2
- 206010070531 Foetal growth restriction Diseases 0.000 claims 2
- 206010019280 Heart failures Diseases 0.000 claims 2
- 208000029422 Hypernatremia Diseases 0.000 claims 2
- 206010020772 Hypertension Diseases 0.000 claims 2
- 206010061218 Inflammation Diseases 0.000 claims 2
- 206010030113 Oedema Diseases 0.000 claims 2
- 208000002193 Pain Diseases 0.000 claims 2
- 208000003782 Raynaud disease Diseases 0.000 claims 2
- 208000012322 Raynaud phenomenon Diseases 0.000 claims 2
- 206010047700 Vomiting Diseases 0.000 claims 2
- 125000000217 alkyl group Chemical group 0.000 claims 2
- 230000036506 anxiety Effects 0.000 claims 2
- 208000030941 fetal growth restriction Diseases 0.000 claims 2
- 230000004054 inflammatory process Effects 0.000 claims 2
- 208000037805 labour Diseases 0.000 claims 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 2
- 201000003152 motion sickness Diseases 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 2
- 201000011461 pre-eclampsia Diseases 0.000 claims 2
- 206010036596 premature ejaculation Diseases 0.000 claims 2
- 125000004076 pyridyl group Chemical group 0.000 claims 2
- 206010039073 rheumatoid arthritis Diseases 0.000 claims 2
- 230000008673 vomiting Effects 0.000 claims 2
- 208000005107 Premature Birth Diseases 0.000 claims 1
- 208000006399 Premature Obstetric Labor Diseases 0.000 claims 1
- 206010036590 Premature baby Diseases 0.000 claims 1
- 206010036600 Premature labour Diseases 0.000 claims 1
- 150000001408 amides Chemical class 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 150000002148 esters Chemical class 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 208000026440 premature labor Diseases 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 239000012453 solvate Substances 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0418980A GB0418980D0 (en) | 2004-08-25 | 2004-08-25 | Triazole compounds useful in therapy |
| US61660104P | 2004-10-05 | 2004-10-05 | |
| PCT/IB2005/002711 WO2006021882A1 (en) | 2004-08-25 | 2005-08-12 | Triazolobenzodiazepines and their use as vasopressin antagonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008510789A JP2008510789A (ja) | 2008-04-10 |
| JP2008510789A5 true JP2008510789A5 (https=) | 2008-07-24 |
Family
ID=35355092
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007529032A Withdrawn JP2008510789A (ja) | 2004-08-25 | 2005-08-12 | トリアゾロベンゾジアゼピン及びバゾプレシンアンタゴニストとしてのそれらの使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7456170B2 (https=) |
| EP (1) | EP1784408A1 (https=) |
| JP (1) | JP2008510789A (https=) |
| BR (1) | BRPI0514458A (https=) |
| CA (1) | CA2578370A1 (https=) |
| MX (1) | MX2007002248A (https=) |
| WO (1) | WO2006021882A1 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT2356123E (pt) * | 2008-11-13 | 2012-10-31 | Hoffmann La Roche | Espiro-5,6-di-hidro-4h-2,3,5,10b-tetra-azabenzo[ e]azulenos |
| RU2510397C2 (ru) | 2008-11-18 | 2014-03-27 | Ф. Хоффманн-Ля Рош Аг | Алкилциклогексиловые эфиры дигидротетраазабензоазуленов |
| BRPI0922303B1 (pt) | 2008-11-28 | 2019-11-12 | Hoffmann La Roche | arilciclo-hexiléteres de di-hidrotetra-azabenzoazulenos, seu processo de preparação, composição farmacêutica que os compreende e uso |
| US8420633B2 (en) * | 2010-03-31 | 2013-04-16 | Hoffmann-La Roche Inc. | Aryl-cyclohexyl-tetraazabenzo[e]azulenes |
| US8461151B2 (en) * | 2010-04-13 | 2013-06-11 | Hoffmann-La Roche Inc. | Aryl-/heteroaryl-cyclohexenyl-tetraazabenzo[e]azulenes |
| US8492376B2 (en) * | 2010-04-21 | 2013-07-23 | Hoffmann-La Roche Inc. | Heteroaryl-cyclohexyl-tetraazabenzo[e]azulenes |
| US8481528B2 (en) * | 2010-04-26 | 2013-07-09 | Hoffmann-La Roche Inc. | Heterobiaryl-cyclohexyl-tetraazabenzo[e]azulenes |
| US8513238B2 (en) * | 2010-05-10 | 2013-08-20 | Hoffmann-La Roche Inc. | Heteroaryl-cyclohexyl-tetraazabenzo[E]azulenes |
| US8828989B2 (en) * | 2011-09-26 | 2014-09-09 | Hoffmann-La Roche Inc. | Oxy-cyclohexyl-4H,6H-5-oxa-2,3,10b-triaza-benzo[E]azulenes as V1A antagonists |
| DK2822953T5 (en) | 2012-03-06 | 2017-09-11 | Pfizer | Macrocyclic derivatives for the treatment of proliferative diseases |
| PE20160203A1 (es) * | 2013-08-19 | 2016-04-20 | Hoffmann La Roche | Antagonistas de via para tratar trastornos del sueno por cambio de fase |
| JP6454707B2 (ja) | 2013-12-05 | 2019-01-16 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | ｔｒａｎｓ−８−クロロ−５−メチル−１−［４−（ピリジン−２−イルオキシ）−シクロヘキシル］−５，６−ジヒドロ−４Ｈ−２，３，５，１０ｂ−テトラアザ−ベンゾ［ｅ］アズレン及びその結晶形態の合成 |
| TW201938171A (zh) | 2017-12-15 | 2019-10-01 | 匈牙利商羅特格登公司 | 作為血管升壓素Ｖ１ａ受體拮抗劑之三環化合物 |
| HU231206B1 (hu) | 2017-12-15 | 2021-10-28 | Richter Gedeon Nyrt. | Triazolobenzazepinek |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR9811585A (pt) | 1997-07-30 | 2000-09-26 | American Home Prod | Agonistas de vasopressinas tricìclicas |
| HRP20040767A2 (en) * | 2002-02-19 | 2004-12-31 | Teva Pharma | Desolvating solvates of atorvastatin hemi-calcium |
| GB0303852D0 (en) | 2003-02-19 | 2003-03-26 | Pfizer Ltd | Triazole compounds useful in therapy |
| US7119088B2 (en) * | 2003-02-19 | 2006-10-10 | Pfizer Inc. | Triazole compounds useful in therapy |
-
2005
- 2005-08-12 CA CA002578370A patent/CA2578370A1/en not_active Abandoned
- 2005-08-12 EP EP05781153A patent/EP1784408A1/en not_active Withdrawn
- 2005-08-12 JP JP2007529032A patent/JP2008510789A/ja not_active Withdrawn
- 2005-08-12 BR BRPI0514458-2A patent/BRPI0514458A/pt not_active IP Right Cessation
- 2005-08-12 MX MX2007002248A patent/MX2007002248A/es unknown
- 2005-08-12 WO PCT/IB2005/002711 patent/WO2006021882A1/en not_active Ceased
- 2005-08-12 US US11/570,694 patent/US7456170B2/en not_active Expired - Fee Related
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