JP2008510719A5 - - Google Patents
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- Publication number
- JP2008510719A5 JP2008510719A5 JP2007528037A JP2007528037A JP2008510719A5 JP 2008510719 A5 JP2008510719 A5 JP 2008510719A5 JP 2007528037 A JP2007528037 A JP 2007528037A JP 2007528037 A JP2007528037 A JP 2007528037A JP 2008510719 A5 JP2008510719 A5 JP 2008510719A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- piperidin
- methyl
- pharmaceutically acceptable
- ylmethoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US60296804P | 2004-08-19 | 2004-08-19 | |
| PCT/US2005/029518 WO2006021002A2 (en) | 2004-08-19 | 2005-08-18 | Compounds useful for inhibiting chk1 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008510719A JP2008510719A (ja) | 2008-04-10 |
| JP2008510719A5 true JP2008510719A5 (enExample) | 2008-10-02 |
Family
ID=35744692
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007528037A Pending JP2008510719A (ja) | 2004-08-19 | 2005-08-18 | Ｃｈｋ１の阻害に有用な化合物 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20080318974A1 (enExample) |
| EP (1) | EP1778648A2 (enExample) |
| JP (1) | JP2008510719A (enExample) |
| KR (1) | KR20070054205A (enExample) |
| CN (1) | CN101115727A (enExample) |
| AU (1) | AU2005272586A1 (enExample) |
| BR (1) | BRPI0514466A (enExample) |
| CA (1) | CA2577880A1 (enExample) |
| MX (1) | MX2007002040A (enExample) |
| WO (1) | WO2006021002A2 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201008005D0 (en) | 2010-05-13 | 2010-06-30 | Sentinel Oncology Ltd | Pharmaceutical compounds |
| GB201119799D0 (en) | 2011-11-16 | 2011-12-28 | Sentinel Oncology Ltd | Pharmaceutical compounds |
| GB201402277D0 (en) | 2014-02-10 | 2014-03-26 | Sentinel Oncology Ltd | Pharmaceutical compounds |
| PE20170268A1 (es) | 2014-06-19 | 2017-04-21 | Ariad Pharma Inc | Compuestos de heteroarilo para la inhibicion de cinasa |
| CN104628659A (zh) * | 2015-01-27 | 2015-05-20 | 广西师范大学 | 具有抗肿瘤作用的吡嗪-芳基脲衍生物及其制备方法与应用 |
| ES2997263T3 (en) | 2016-01-11 | 2025-02-14 | Celator Pharmaceuticals Inc | Inhibiting ataxia telangiectasia and rad3-related protein (atr) |
| DK3411036T3 (da) | 2016-02-04 | 2022-01-17 | Pharmaengine Inc | 3,5-disubstituerede pyrazoler, der er nyttige som checkpoint-kinase 1 (chk1)-hæmmere, samt fremstilling og anvendelse deraf |
| AU2018243667A1 (en) | 2017-03-31 | 2019-10-17 | Seagen Inc. | Combinations of Chk1- and Wee1 - inhibitors |
| KR20200144579A (ko) | 2018-05-14 | 2020-12-29 | 어리어드 파마슈티칼스, 인코포레이티드 | 피리미딘 유도체의 약학 염 및 장애의 치료 방법 |
| CN112457306A (zh) | 2019-09-06 | 2021-03-09 | 上海瑛派药业有限公司 | 3,5-二取代吡唑化合物作为激酶抑制剂及其应用 |
| ES3014705T3 (en) * | 2019-11-29 | 2025-04-24 | Novaonco Js Therapeutics Co Ltd | Diazaindole derivative and use thereof as chk1 inhibitor |
| WO2021119236A1 (en) | 2019-12-10 | 2021-06-17 | Seagen Inc. | Preparation of a chk1 inhibitor compound |
| GB202107932D0 (en) | 2021-06-03 | 2021-07-21 | Sentinel Oncology Ltd | Preparation of a CHK1 Inhibitor Compound |
| GB202107924D0 (en) | 2021-06-03 | 2021-07-21 | Sentinel Oncology Ltd | A pharmaceutical salt |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL254871A (enExample) * | 1959-08-14 | |||
| CH493480A (de) * | 1969-01-31 | 1970-07-15 | Agripat Sa | Verfahren zur Herstellung von neuen O,N-Diphenyl-carbaminsäureestern |
| US4071524A (en) * | 1976-11-08 | 1978-01-31 | Riker Laboratories, Inc. | Derivatives of urea |
| EP1449834A3 (en) * | 1997-12-22 | 2004-12-22 | Bayer Corporation | Inhibition of raf kinase using symmetrical and unsymmetrical substituted diphenyl ureas |
| UA76977C2 (en) * | 2001-03-02 | 2006-10-16 | Icos Corp | Aryl- and heteroaryl substituted chk1 inhibitors and their use as radiosensitizers and chemosensitizers |
| JP4901102B2 (ja) * | 2002-05-03 | 2012-03-21 | エクセリクシス， インク． | プロテインキナーゼモジュレーターおよびその使用方法 |
| CA2539320A1 (en) * | 2003-09-17 | 2005-03-31 | Icos Corporation | Use of chk1 inhibitors to control cell proliferation |
| BRPI0512593A (pt) * | 2004-06-25 | 2008-03-25 | Icos Corp | composto ou um sal ou pró-droga ou solvato farmaceuticamente aceitável do mesmo, composição, e, métodos de inibir a quinase 1 de ponto de verificação em uma célula, de sensibilizar células em um indivìduo e de inibir a proliferação de célula aberrante |
| CN101010316A (zh) * | 2004-07-02 | 2007-08-01 | 艾科斯有限公司 | 用于抑制chk1的化合物 |
-
2005
- 2005-08-18 CN CNA2005800353820A patent/CN101115727A/zh active Pending
- 2005-08-18 JP JP2007528037A patent/JP2008510719A/ja active Pending
- 2005-08-18 CA CA002577880A patent/CA2577880A1/en not_active Abandoned
- 2005-08-18 BR BRPI0514466-3A patent/BRPI0514466A/pt not_active IP Right Cessation
- 2005-08-18 US US11/659,389 patent/US20080318974A1/en not_active Abandoned
- 2005-08-18 WO PCT/US2005/029518 patent/WO2006021002A2/en not_active Ceased
- 2005-08-18 AU AU2005272586A patent/AU2005272586A1/en not_active Abandoned
- 2005-08-18 MX MX2007002040A patent/MX2007002040A/es not_active Application Discontinuation
- 2005-08-18 KR KR1020077006216A patent/KR20070054205A/ko not_active Withdrawn
- 2005-08-18 EP EP05810303A patent/EP1778648A2/en not_active Withdrawn