|
ES2281252B1
(es)
*
|
2005-07-27 |
2009-02-16 |
Consejo Superior De Investigaciones Cientificas |
Vectores recombinantes basados en el virus modificado de ankara (mva) como vacunas preventivas y terapeuticas contra el sida.
|
|
SMT202000101T1
(it)
|
2008-10-10 |
2020-03-13 |
Childrens Medical Center |
Vaccino con trimero di env di hiv-1 stabilizzato biochimicamente
|
|
GB0823497D0
(en)
|
2008-12-24 |
2009-01-28 |
Isis Innovation |
Immunogenic composition and use thereof
|
|
WO2010096561A1
(en)
|
2009-02-18 |
2010-08-26 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Synthetic hiv/siv gag proteins and uses thereof
|
|
US20110177115A1
(en)
*
|
2009-10-02 |
2011-07-21 |
Tomas Hanke |
Vaccination regimen
|
|
US20110200573A1
(en)
*
|
2010-02-04 |
2011-08-18 |
Derya Unutmaz |
Methods of inhibiting retrovirus replication and infectivity
|
|
WO2011116351A2
(en)
|
2010-03-19 |
2011-09-22 |
University Of South Alabama |
Methods and compositions for the treatment of cancer
|
|
WO2012021730A2
(en)
*
|
2010-08-11 |
2012-02-16 |
Genvec, Inc. |
Respiratory syncytial virus (rsv) vaccine
|
|
US9458456B2
(en)
|
2011-04-01 |
2016-10-04 |
University Of South Alabama |
Methods and compositions for the diagnosis, classification, and treatment of cancer
|
|
WO2013103401A1
(en)
|
2012-01-06 |
2013-07-11 |
University Of South Alabama |
Methods and compositions for the treatment of cancer
|
|
EP2931899A1
(en)
|
2012-12-12 |
2015-10-21 |
The Broad Institute, Inc. |
Functional genomics using crispr-cas systems, compositions, methods, knock out libraries and applications thereof
|
|
EP2932421A1
(en)
|
2012-12-12 |
2015-10-21 |
The Broad Institute, Inc. |
Methods, systems, and apparatus for identifying target sequences for cas enzymes or crispr-cas systems for target sequences and conveying results thereof
|
|
KR20150105956A
(ko)
|
2012-12-12 |
2015-09-18 |
더 브로드 인스티튜트, 인코퍼레이티드 |
서열 조작 및 치료적 적용을 위한 시스템, 방법 및 조성물의 전달, 유전자 조작 및 최적화
|
|
ES2576126T3
(es)
|
2012-12-12 |
2016-07-05 |
The Broad Institute, Inc. |
Modificación por tecnología genética y optimización de sistemas, métodos y composiciones enzimáticas mejorados para la manipulación de secuencias
|
|
CN105263506B
(zh)
|
2013-01-07 |
2018-03-09 |
贝丝以色列女执事医疗中心 |
稳定的人免疫缺陷病毒(HIV)包膜(EnV)三聚体疫苗及其使用方法
|
|
CN107995927B
(zh)
|
2013-06-17 |
2021-07-30 |
布罗德研究所有限公司 |
用于肝靶向和治疗的crispr-cas系统、载体和组合物的递送与用途
|
|
CN105492611A
(zh)
|
2013-06-17 |
2016-04-13 |
布罗德研究所有限公司 |
用于序列操纵的优化的crispr-cas双切口酶系统、方法以及组合物
|
|
JP6738729B2
(ja)
|
2013-06-17 |
2020-08-12 |
ザ・ブロード・インスティテュート・インコーポレイテッド |
分裂終了細胞の疾患および障害をターゲティングおよびモデリングするための系、方法および組成物の送達、エンジニアリングおよび最適化
|
|
CA2915795C
(en)
|
2013-06-17 |
2021-07-13 |
The Broad Institute, Inc. |
Delivery, use and therapeutic applications of the crispr-cas systems and compositions for targeting disorders and diseases using viral components
|
|
EP3674411A1
(en)
|
2013-06-17 |
2020-07-01 |
The Broad Institute, Inc. |
Delivery, engineering and optimization of tandem guide systems, methods and compositions for sequence manipulation
|
|
WO2015009946A1
(en)
*
|
2013-07-17 |
2015-01-22 |
Emory University |
Method of increasing immune response to hiv antigens
|
|
WO2015077717A1
(en)
|
2013-11-25 |
2015-05-28 |
The Broad Institute Inc. |
Compositions and methods for diagnosing, evaluating and treating cancer by means of the dna methylation status
|
|
US11725237B2
(en)
|
2013-12-05 |
2023-08-15 |
The Broad Institute Inc. |
Polymorphic gene typing and somatic change detection using sequencing data
|
|
EP3079726B1
(en)
|
2013-12-12 |
2018-12-05 |
The Broad Institute, Inc. |
Delivery, use and therapeutic applications of the crispr-cas systems and compositions for targeting disorders and diseases using particle delivery components
|
|
EP3540051B1
(en)
|
2013-12-12 |
2022-08-17 |
The Broad Institute, Inc. |
Delivery, use and therapeutic applications of the crispr-cas systems and compositions for hsv and viral diseases and disorders.
|
|
SG10201804973TA
(en)
|
2013-12-12 |
2018-07-30 |
Broad Inst Inc |
Compositions and Methods of Use of Crispr-Cas Systems in Nucleotide Repeat Disorders
|
|
EP3080271B1
(en)
|
2013-12-12 |
2020-02-12 |
The Broad Institute, Inc. |
Systems, methods and compositions for sequence manipulation with optimized functional crispr-cas systems
|
|
BR112016013201B1
(pt)
|
2013-12-12 |
2023-01-31 |
The Broad Institute, Inc. |
Uso de uma composição compreendendo um sistema crispr-cas no tratamento de uma doença genética ocular
|
|
EP3080259B1
(en)
|
2013-12-12 |
2023-02-01 |
The Broad Institute, Inc. |
Engineering of systems, methods and optimized guide compositions with new architectures for sequence manipulation
|
|
EP3082853A2
(en)
|
2013-12-20 |
2016-10-26 |
The Broad Institute, Inc. |
Combination therapy with neoantigen vaccine
|
|
DK4023249T3
(da)
|
2014-04-23 |
2025-01-13 |
Modernatx Inc |
Nukleinsyrevacciner
|
|
EP3180426B1
(en)
|
2014-08-17 |
2019-12-25 |
The Broad Institute, Inc. |
Genome editing using cas9 nickases
|
|
WO2016049024A2
(en)
|
2014-09-24 |
2016-03-31 |
The Broad Institute Inc. |
Delivery, use and therapeutic applications of the crispr-cas systems and compositions for modeling competition of multiple cancer mutations in vivo
|
|
WO2016049163A2
(en)
|
2014-09-24 |
2016-03-31 |
The Broad Institute Inc. |
Use and production of chd8+/- transgenic animals with behavioral phenotypes characteristic of autism spectrum disorder
|
|
WO2016049251A1
(en)
|
2014-09-24 |
2016-03-31 |
The Broad Institute Inc. |
Delivery, use and therapeutic applications of the crispr-cas systems and compositions for modeling mutations in leukocytes
|
|
WO2016049258A2
(en)
|
2014-09-25 |
2016-03-31 |
The Broad Institute Inc. |
Functional screening with optimized functional crispr-cas systems
|
|
CA2961024A1
(en)
|
2014-09-26 |
2016-03-31 |
Beth Israel Deaconess Medical Center, Inc. |
Methods and compositions for inducing protective immunity against human immunodeficiency virus infection
|
|
EP3212788A2
(en)
|
2014-10-27 |
2017-09-06 |
The Broad Institute, Inc. |
Compositions, methods and use of synthetic lethal screening
|
|
WO2016094874A1
(en)
|
2014-12-12 |
2016-06-16 |
The Broad Institute Inc. |
Escorted and functionalized guides for crispr-cas systems
|
|
WO2016094880A1
(en)
|
2014-12-12 |
2016-06-16 |
The Broad Institute Inc. |
Delivery, use and therapeutic applications of crispr systems and compositions for genome editing as to hematopoietic stem cells (hscs)
|
|
EP3889260A1
(en)
|
2014-12-12 |
2021-10-06 |
The Broad Institute, Inc. |
Protected guide rnas (pgrnas)
|
|
WO2016094872A1
(en)
|
2014-12-12 |
2016-06-16 |
The Broad Institute Inc. |
Dead guides for crispr transcription factors
|
|
WO2016100975A1
(en)
|
2014-12-19 |
2016-06-23 |
Massachsetts Institute Ot Technology |
Molecular biomarkers for cancer immunotherapy
|
|
EP3234192B1
(en)
|
2014-12-19 |
2021-07-14 |
The Broad Institute, Inc. |
Unbiased identification of double-strand breaks and genomic rearrangement by genome-wide insert capture sequencing
|
|
WO2016100977A1
(en)
|
2014-12-19 |
2016-06-23 |
The Broad Institute Inc. |
Methods for profiling the t-cel- receptor repertoire
|
|
WO2016106236A1
(en)
|
2014-12-23 |
2016-06-30 |
The Broad Institute Inc. |
Rna-targeting system
|
|
EP3237615B2
(en)
|
2014-12-24 |
2023-07-26 |
The Broad Institute, Inc. |
Crispr having or associated with destabilization domains
|
|
CR20200476A
(es)
|
2015-05-20 |
2020-12-02 |
Dana Farber Cancer Inst Inc |
ANTÍGENOS COMPARTIDOS (Divisional 2017-0584)
|
|
EP3307781B8
(en)
|
2015-06-10 |
2020-12-02 |
The Broad Institute, Inc. |
Antibodies, compounds and screens for identifying and treating cachexia or pre-cachexia
|
|
US9790490B2
(en)
|
2015-06-18 |
2017-10-17 |
The Broad Institute Inc. |
CRISPR enzymes and systems
|
|
WO2016205745A2
(en)
*
|
2015-06-18 |
2016-12-22 |
The Broad Institute Inc. |
Cell sorting
|
|
CA3012631A1
(en)
|
2015-06-18 |
2016-12-22 |
The Broad Institute Inc. |
Novel crispr enzymes and systems
|
|
AU2016279062A1
(en)
|
2015-06-18 |
2019-03-28 |
Omar O. Abudayyeh |
Novel CRISPR enzymes and systems
|
|
CN109536474A
(zh)
|
2015-06-18 |
2019-03-29 |
布罗德研究所有限公司 |
降低脱靶效应的crispr酶突变
|
|
US11214800B2
(en)
|
2015-08-18 |
2022-01-04 |
The Broad Institute, Inc. |
Methods and compositions for altering function and structure of chromatin loops and/or domains
|
|
WO2017069958A2
(en)
|
2015-10-09 |
2017-04-27 |
The Brigham And Women's Hospital, Inc. |
Modulation of novel immune checkpoint targets
|
|
KR102761827B1
(ko)
|
2015-10-22 |
2025-02-03 |
더 브로드 인스티튜트, 인코퍼레이티드 |
타입 vi-b crispr 효소 및 시스템
|
|
EP3368687B1
(en)
|
2015-10-27 |
2021-09-29 |
The Broad Institute, Inc. |
Compositions and methods for targeting cancer-specific sequence variations
|
|
WO2017075465A1
(en)
|
2015-10-28 |
2017-05-04 |
The Broad Institute Inc. |
Compositions and methods for evaluating and modulating immune responses by detecting and targeting gata3
|
|
WO2017075451A1
(en)
|
2015-10-28 |
2017-05-04 |
The Broad Institute Inc. |
Compositions and methods for evaluating and modulating immune responses by detecting and targeting pou2af1
|
|
EP3368689B1
(en)
|
2015-10-28 |
2020-06-17 |
The Broad Institute, Inc. |
Composition for modulating immune responses by use of immune cell gene signature
|
|
CA3008542C
(en)
*
|
2015-12-15 |
2020-06-02 |
Janssen Vaccines & Prevention B.V. |
Human immunodeficiency virus antigens, vectors, compositions, and methods of use thereof
|
|
US12110490B2
(en)
|
2015-12-18 |
2024-10-08 |
The Broad Institute, Inc. |
CRISPR enzymes and systems
|
|
EP3446119A1
(en)
|
2016-04-18 |
2019-02-27 |
The Broad Institute Inc. |
Improved hla epitope prediction
|
|
WO2017189308A1
(en)
|
2016-04-19 |
2017-11-02 |
The Broad Institute Inc. |
Novel crispr enzymes and systems
|
|
US11286478B2
(en)
|
2016-04-19 |
2022-03-29 |
The Broad Institute, Inc. |
Cpf1 complexes with reduced indel activity
|
|
KR102424476B1
(ko)
|
2016-04-19 |
2022-07-25 |
더 브로드 인스티튜트, 인코퍼레이티드 |
신규한 crispr 효소 및 시스템
|
|
EP3463290A4
(en)
*
|
2016-06-03 |
2019-10-30 |
Temple University - Of The Commonwealth System of Higher Education |
REGULATION OF THE NEGATIVE RECONSTITUTION OF HIV-1 BY GENETIZATION STRATEGY
|
|
JP6595132B2
(ja)
|
2016-06-16 |
2019-10-23 |
ヤンセン ファッシンズ アンド プリベンション ベーフェー |
Hivワクチン製剤
|
|
JP7267013B2
(ja)
|
2016-06-17 |
2023-05-01 |
ザ・ブロード・インスティテュート・インコーポレイテッド |
Vi型crisprオルソログ及び系
|
|
US20210222164A1
(en)
|
2016-06-29 |
2021-07-22 |
The Broad Institute, Inc. |
Crispr-cas systems having destabilization domain
|
|
WO2018035387A1
(en)
|
2016-08-17 |
2018-02-22 |
The Broad Institute, Inc. |
Novel crispr enzymes and systems
|
|
US11352647B2
(en)
|
2016-08-17 |
2022-06-07 |
The Broad Institute, Inc. |
Crispr enzymes and systems
|
|
CN110494159A
(zh)
|
2016-09-02 |
2019-11-22 |
扬森疫苗与预防公司 |
在接受抗逆转录病毒治疗的对象中诱导针对人类免疫缺陷病毒感染的免疫应答的方法
|
|
WO2018049025A2
(en)
|
2016-09-07 |
2018-03-15 |
The Broad Institute Inc. |
Compositions and methods for evaluating and modulating immune responses
|
|
SG10202001956UA
(en)
|
2016-09-15 |
2020-04-29 |
Janssen Vaccines & Prevention Bv |
Trimer stabilizing hiv envelope protein mutations
|
|
US12447213B2
(en)
|
2016-10-07 |
2025-10-21 |
The Broad Institute, Inc. |
Modulation of novel immune checkpoint targets
|
|
WO2018140391A1
(en)
|
2017-01-24 |
2018-08-02 |
The Broad Institute, Inc. |
Compositions and methods for detecting a mutant variant of a polynucleotide
|
|
EP4361261A3
(en)
|
2017-03-15 |
2024-07-10 |
The Broad Institute Inc. |
Novel cas13b orthologues crispr enzymes and systems
|
|
CN110799645B
(zh)
|
2017-04-12 |
2024-08-02 |
博德研究所 |
新型vi型crispr直系同源物和系统
|
|
WO2018191750A2
(en)
|
2017-04-14 |
2018-10-18 |
The Broad Institute Inc. |
Novel delivery of large payloads
|
|
WO2018204777A2
(en)
|
2017-05-05 |
2018-11-08 |
The Broad Institute, Inc. |
Methods for identification and modification of lncrna associated with target genotypes and phenotypes
|
|
WO2018208910A1
(en)
|
2017-05-09 |
2018-11-15 |
The Broad Institute Inc. |
Gut microbiome function predicts response to anti-integrin biologic therapy in inflammatory bowel diseases
|
|
US12297436B2
(en)
|
2017-05-18 |
2025-05-13 |
The Broad Institute, Inc. |
Systems, methods, and compositions for targeted nucleic acid editing
|
|
EP3638302B1
(en)
|
2017-06-15 |
2024-03-13 |
Janssen Vaccines & Prevention B.V. |
Poxvirus vectors encoding hiv antigens, and methods of use thereof
|
|
JP7454494B2
(ja)
|
2017-06-26 |
2024-03-22 |
ザ・ブロード・インスティテュート・インコーポレイテッド |
標的化された核酸編集のためのcrispr/cas-アデニンデアミナーゼ系の組成物、系及び方法
|
|
US10392616B2
(en)
|
2017-06-30 |
2019-08-27 |
Arbor Biotechnologies, Inc. |
CRISPR RNA targeting enzymes and systems and uses thereof
|
|
MY200554A
(en)
|
2017-07-19 |
2024-01-03 |
Janssen Vaccines & Prevention Bv |
Trimer stabilizing hiv envelope protein mutations
|
|
KR102338449B1
(ko)
|
2017-09-21 |
2021-12-10 |
더 브로드 인스티튜트, 인코퍼레이티드 |
표적화된 핵산 편집을 위한 시스템, 방법, 및 조성물
|
|
WO2019071054A1
(en)
|
2017-10-04 |
2019-04-11 |
The Broad Institute, Inc. |
METHODS AND COMPOSITIONS FOR MODIFYING THE FUNCTION AND STRUCTURE OF BUCKLES AND / OR CHROMATIN DOMAINS
|
|
WO2019135816A2
(en)
|
2017-10-23 |
2019-07-11 |
The Broad Institute, Inc. |
Novel nucleic acid modifiers
|
|
WO2019089803A1
(en)
|
2017-10-31 |
2019-05-09 |
The Broad Institute, Inc. |
Methods and compositions for studying cell evolution
|
|
WO2019090174A1
(en)
|
2017-11-02 |
2019-05-09 |
Arbor Biotechnologies, Inc. |
Novel crispr-associated transposon systems and components
|
|
WO2019094984A1
(en)
|
2017-11-13 |
2019-05-16 |
The Broad Institute, Inc. |
Methods for determining spatial and temporal gene expression dynamics during adult neurogenesis in single cells
|
|
WO2019094983A1
(en)
|
2017-11-13 |
2019-05-16 |
The Broad Institute, Inc. |
Methods and compositions for treating cancer by targeting the clec2d-klrb1 pathway
|
|
US20230193242A1
(en)
|
2017-12-22 |
2023-06-22 |
The Broad Institute, Inc. |
Cas12b systems, methods, and compositions for targeted dna base editing
|
|
ES2952978T3
(es)
|
2018-03-14 |
2023-11-07 |
Arbor Biotechnologies Inc |
Sistemas y enzimas novedosos de direccionamiento a ADN de CRISPR
|
|
EP4253551A3
(en)
|
2018-03-14 |
2024-01-24 |
Arbor Biotechnologies, Inc. |
Novel crispr dna and rna targeting enzymes and systems
|
|
US10968257B2
(en)
|
2018-04-03 |
2021-04-06 |
The Broad Institute, Inc. |
Target recognition motifs and uses thereof
|
|
KR20250133482A
(ko)
|
2018-05-11 |
2025-09-05 |
빔 테라퓨틱스, 인크. |
프로그래밍가능한 염기 편집기 시스템을 이용하여 단일 뉴클레오티드 다형성을 편집하는 방법
|
|
US20210198664A1
(en)
|
2018-05-16 |
2021-07-01 |
Arbor Biotechnologies, Inc. |
Novel crispr-associated systems and components
|
|
WO2020018142A1
(en)
|
2018-07-16 |
2020-01-23 |
Arbor Biotechnologies, Inc. |
Novel crispr dna targeting enzymes and systems
|
|
EP3830263A4
(en)
|
2018-08-03 |
2022-05-04 |
Beam Therapeutics, Inc. |
Multi-effector nucleobase editors and methods of using same to modify a nucleic acid target sequence
|
|
EP3833761A1
(en)
|
2018-08-07 |
2021-06-16 |
The Broad Institute, Inc. |
Novel cas12b enzymes and systems
|
|
WO2020041380A1
(en)
|
2018-08-20 |
2020-02-27 |
The Broad Institute, Inc. |
Methods and compositions for optochemical control of crispr-cas9
|
|
US20210382068A1
(en)
|
2018-10-02 |
2021-12-09 |
Dana-Farber Cancer Institute, Inc. |
Hla single allele lines
|
|
US20220062394A1
(en)
|
2018-12-17 |
2022-03-03 |
The Broad Institute, Inc. |
Methods for identifying neoantigens
|
|
WO2020131862A1
(en)
|
2018-12-17 |
2020-06-25 |
The Broad Institute, Inc. |
Crispr-associated transposase systems and methods of use thereof
|
|
WO2020127990A1
(en)
|
2018-12-20 |
2020-06-25 |
Biomedrex Ab |
System for production of crispr-based pharmaceutical compositions
|
|
CA3127527A1
(en)
|
2019-02-12 |
2020-08-20 |
Universita Degli Studi Di Trento |
Cas12a guide rna molecules and uses thereof
|
|
WO2020169705A1
(en)
|
2019-02-20 |
2020-08-27 |
Biomedrex Ab |
Virus therapy
|
|
US12215382B2
(en)
|
2019-03-01 |
2025-02-04 |
The General Hospital Corporation |
Liver protective MARC variants and uses thereof
|
|
US12419915B2
(en)
|
2019-03-13 |
2025-09-23 |
The Broad Institute, Inc. |
Microglial progenitors for regeneration of functional microglia in the central nervous system and therapeutics uses thereof
|
|
MA55321A
(fr)
*
|
2019-03-15 |
2022-01-19 |
Modernatx Inc |
Vaccins à base d'arn contre le vih
|
|
WO2020191102A1
(en)
|
2019-03-18 |
2020-09-24 |
The Broad Institute, Inc. |
Type vii crispr proteins and systems
|
|
US20220249701A1
(en)
|
2019-05-14 |
2022-08-11 |
The Broad Institute, Inc. |
Compositions and methods for targeting multinucleated cells
|
|
US20220235340A1
(en)
|
2019-05-20 |
2022-07-28 |
The Broad Institute, Inc. |
Novel crispr-cas systems and uses thereof
|
|
EP3999642A1
(en)
|
2019-07-19 |
2022-05-25 |
Flagship Pioneering Innovations VI, LLC |
Recombinase compositions and methods of use
|
|
WO2021041922A1
(en)
|
2019-08-30 |
2021-03-04 |
The Broad Institute, Inc. |
Crispr-associated mu transposase systems
|
|
EP4028514A1
(en)
|
2019-09-09 |
2022-07-20 |
Beam Therapeutics Inc. |
Novel crispr enzymes, methods, systems and uses thereof
|
|
CA3150454A1
(en)
|
2019-09-09 |
2021-03-18 |
Arbor Biotechnologies, Inc. |
Novel crispr dna targeting enzymes and systems
|
|
AU2020347276A1
(en)
|
2019-09-12 |
2022-03-17 |
Massachusetts Institute Of Technology |
Engineered adeno-associated virus capsids
|
|
US12297426B2
(en)
|
2019-10-01 |
2025-05-13 |
The Broad Institute, Inc. |
DNA damage response signature guided rational design of CRISPR-based systems and therapies
|
|
US12394502B2
(en)
|
2019-10-02 |
2025-08-19 |
The General Hospital Corporation |
Method for predicting HLA-binding peptides using protein structural features
|
|
CA3153902A1
(en)
|
2019-10-16 |
2021-04-22 |
Pardis SABETI |
Engineered muscle targeting compositions
|
|
EP4069838A1
(en)
|
2019-12-03 |
2022-10-12 |
Beam Therapeutics Inc. |
Synthetic guide rna, compositions, methods, and uses thereof
|
|
WO2021152181A1
(en)
|
2020-01-30 |
2021-08-05 |
Biomedrex Ab |
Virus therapy
|
|
AU2021230546A1
(en)
|
2020-03-04 |
2022-10-13 |
Flagship Pioneering Innovations Vi, Llc |
Methods and compositions for modulating a genome
|
|
AU2021280261A1
(en)
|
2020-05-26 |
2023-01-19 |
Dionis Therapeutics, Inc. |
Nucleic acid artificial mini-proteome libraries
|
|
US12419948B2
(en)
|
2020-08-31 |
2025-09-23 |
The Broad Institute, Inc. |
Immunogenic compositions and use thereof
|
|
WO2022188039A1
(en)
|
2021-03-09 |
2022-09-15 |
Huigene Therapeutics Co., Ltd. |
Engineered crispr/cas13 system and uses thereof
|
|
WO2022068912A1
(en)
|
2020-09-30 |
2022-04-07 |
Huigene Therapeutics Co., Ltd. |
Engineered crispr/cas13 system and uses thereof
|
|
EP4305157A1
(en)
|
2021-03-09 |
2024-01-17 |
Huidagene Therapeutics (Singapore) Pte. Ltd. |
Engineered crispr/cas13 system and uses thereof
|
|
KR20230158531A
(ko)
|
2021-03-23 |
2023-11-20 |
빔 테라퓨틱스, 인크. |
신규 crispr 효소, 방법, 시스템 및 그 용도
|
|
JP2024514649A
(ja)
|
2021-04-16 |
2024-04-02 |
ビーム セラピューティクス インク. |
肝細胞の遺伝子修飾
|
|
JP2024522112A
(ja)
|
2021-05-27 |
2024-06-11 |
中国科学院動物研究所 |
エンジニアリングされたCas12iヌクレアーゼ、エフェクタータンパク質及びその用途
|
|
CA3221008A1
(en)
|
2021-06-02 |
2022-12-08 |
Brian CAFFERTY |
Circular guide rnas for crispr/cas editing systems
|
|
CA3225121A1
(en)
|
2021-07-20 |
2023-01-26 |
Benjamin DEVERMAN |
Engineered targeting compositions for endothelial cells of the central nervous system vasculature and methods of use thereof
|
|
CA3226664A1
(en)
|
2021-07-23 |
2023-01-26 |
Brian CAFFERTY |
Guide rnas for crispr/cas editing systems
|
|
CA3231677A1
(en)
|
2021-09-08 |
2023-03-16 |
Flagship Pioneering Innovations Vi, Llc |
Methods and compositions for modulating a genome
|
|
EP4426828A1
(en)
|
2021-11-01 |
2024-09-11 |
Tome Biosciences, Inc. |
Single construct platform for simultaneous delivery of gene editing machinery and nucleic acid cargo
|
|
EP4437092A1
(en)
|
2021-11-26 |
2024-10-02 |
Epigenic Therapeutics Inc. |
Method of modulating pcsk9 and uses thereof
|
|
KR20240116827A
(ko)
|
2021-12-17 |
2024-07-30 |
빔 테라퓨틱스, 인크. |
신규한 crispr 효소, 방법, 시스템 및 이의 용도
|
|
CA3244180A1
(en)
|
2021-12-22 |
2023-06-29 |
Tome Biosciences Inc |
CO-ADMINISTRATION OF A GENE EDITOR CONSTRUCTION AND A PATTERN DONOR
|
|
WO2023196772A1
(en)
|
2022-04-04 |
2023-10-12 |
Beam Therapeutics Inc. |
Novel rna base editing compositions, systems, methods and uses thereof
|
|
WO2023205744A1
(en)
|
2022-04-20 |
2023-10-26 |
Tome Biosciences, Inc. |
Programmable gene insertion compositions
|
|
WO2023215831A1
(en)
|
2022-05-04 |
2023-11-09 |
Tome Biosciences, Inc. |
Guide rna compositions for programmable gene insertion
|
|
EP4526324A1
(en)
|
2022-05-18 |
2025-03-26 |
The Broad Institute, Inc. |
Engineered viral capsids with increased stability and methods of use thereof
|
|
WO2023225670A2
(en)
|
2022-05-20 |
2023-11-23 |
Tome Biosciences, Inc. |
Ex vivo programmable gene insertion
|
|
WO2024015892A1
(en)
|
2022-07-13 |
2024-01-18 |
The Broad Institute, Inc. |
Hla-ii immunopeptidome methods and systems for antigen discovery
|
|
WO2024016003A2
(en)
|
2022-07-14 |
2024-01-18 |
The Broad Institute, Inc. |
Aav capsids that enable cns-wide gene delivery through interactions with the transferrin receptor
|
|
WO2024020587A2
(en)
|
2022-07-22 |
2024-01-25 |
Tome Biosciences, Inc. |
Pleiopluripotent stem cell programmable gene insertion
|
|
EP4587560A1
(en)
|
2022-09-16 |
2025-07-23 |
Beam Therapeutics Inc. |
Large serine recombinases, systems and uses thereof
|
|
WO2024138194A1
(en)
|
2022-12-22 |
2024-06-27 |
Tome Biosciences, Inc. |
Platforms, compositions, and methods for in vivo programmable gene insertion
|
|
WO2024163842A2
(en)
|
2023-02-03 |
2024-08-08 |
The Broad Institute, Inc. |
Delivering genes to the brain endothelium to treat lysosomal storage disorder-derived neuropathology
|
|
WO2024168253A1
(en)
|
2023-02-10 |
2024-08-15 |
Possible Medicines Llc |
Delivery of an rna guided recombination system
|
|
WO2024168265A1
(en)
|
2023-02-10 |
2024-08-15 |
Possible Medicines Llc |
Aav delivery of rna guided recombination system
|
|
WO2024234006A1
(en)
|
2023-05-11 |
2024-11-14 |
Tome Biosciences, Inc. |
Systems, compositions, and methods for targeting liver sinusodial endothelial cells (lsecs)
|
|
WO2025050069A1
(en)
|
2023-09-01 |
2025-03-06 |
Tome Biosciences, Inc. |
Programmable gene insertion using engineered integration enzymes
|
|
WO2025059533A1
(en)
|
2023-09-13 |
2025-03-20 |
The Broad Institute, Inc. |
Crispr enzymes and systems
|
|
WO2025097055A2
(en)
|
2023-11-02 |
2025-05-08 |
The Broad Institute, Inc. |
Compositions and methods of use of t cells in immunotherapy
|
|
WO2025106663A1
(en)
|
2023-11-15 |
2025-05-22 |
Slate Bio, Inc. |
Interleukin-33 variants, compositions and uses thereof
|
|
WO2025106677A1
(en)
|
2023-11-15 |
2025-05-22 |
Slate Bio, Inc. |
Bifunctional il-2 and il-33 proteins for treating autoimmune disease
|
|
WO2025106685A1
(en)
|
2023-11-15 |
2025-05-22 |
Slate Bio, Inc. |
Interleukin-2 superkine and interleukin-33, compositions and uses thereof
|
|
WO2025117544A1
(en)
|
2023-11-29 |
2025-06-05 |
The Broad Institute, Inc. |
Engineered omega guide molecule and iscb compositions, systems, and methods of use thereof
|
|
WO2025155923A1
(en)
|
2024-01-17 |
2025-07-24 |
The Broad Institute, Inc. |
Aav capsid modifications that enable improved cns-wide gene delivery through interactions with the transferrin receptor
|
|
WO2025160155A1
(en)
|
2024-01-22 |
2025-07-31 |
The Broad Institute, Inc. |
Epigenetic targeting of prion diseases
|
|
WO2025188687A1
(en)
|
2024-03-04 |
2025-09-12 |
Beam Therapeutics Inc. |
Stable rna compositions with stem loop, and methods thereof
|
|
WO2025217163A2
(en)
|
2024-04-08 |
2025-10-16 |
The Broad Institute, Inc. |
Novel aav capsids binding to human cd59
|
|
WO2025217174A1
(en)
|
2024-04-08 |
2025-10-16 |
The Broad Institute, Inc. |
Aav capsid modifications that enable improved cns-wide gene delivery through interactions with carbonic anhydrase iv
|
|
WO2025224107A1
(en)
|
2024-04-22 |
2025-10-30 |
Basecamp Research Ltd |
Method and compositions for detecting off-target editing
|
|
WO2025224182A2
(en)
|
2024-04-23 |
2025-10-30 |
Basecamp Research Ltd |
Single construct platform for simultaneous delivery of gene editing machinery and nucleic acid cargo
|