JP2008507719A - 共焦点蛍光顕微鏡法及び装置 - Google Patents
共焦点蛍光顕微鏡法及び装置 Download PDFInfo
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- JP2008507719A JP2008507719A JP2007522050A JP2007522050A JP2008507719A JP 2008507719 A JP2008507719 A JP 2008507719A JP 2007522050 A JP2007522050 A JP 2007522050A JP 2007522050 A JP2007522050 A JP 2007522050A JP 2008507719 A JP2008507719 A JP 2008507719A
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- 238000001218 confocal laser scanning microscopy Methods 0.000 title abstract description 5
- 230000003287 optical effect Effects 0.000 claims description 60
- 230000005284 excitation Effects 0.000 claims description 42
- 238000003384 imaging method Methods 0.000 claims description 36
- 238000000034 method Methods 0.000 claims description 30
- 238000005096 rolling process Methods 0.000 claims description 18
- 238000001514 detection method Methods 0.000 claims description 17
- 238000005286 illumination Methods 0.000 claims description 16
- 238000007493 shaping process Methods 0.000 claims description 9
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- 238000010226 confocal imaging Methods 0.000 abstract description 8
- 238000005516 engineering process Methods 0.000 abstract description 3
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- 239000000835 fiber Substances 0.000 description 2
- 238000002073 fluorescence micrograph Methods 0.000 description 2
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- 238000003556 assay Methods 0.000 description 1
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- 238000004624 confocal microscopy Methods 0.000 description 1
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- 238000000799 fluorescence microscopy Methods 0.000 description 1
- 239000007850 fluorescent dye Substances 0.000 description 1
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- 238000010191 image analysis Methods 0.000 description 1
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Classifications
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
- G02B21/002—Scanning microscopes
- G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
- G02B21/0052—Optical details of the image generation
- G02B21/0076—Optical details of the image generation arrangements using fluorescence or luminescence
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
- G02B21/002—Scanning microscopes
- G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
- G02B21/0036—Scanning details, e.g. scanning stages
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
- G02B21/002—Scanning microscopes
- G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
- G02B21/0052—Optical details of the image generation
- G02B21/0064—Optical details of the image generation multi-spectral or wavelength-selective arrangements, e.g. wavelength fan-out, chromatic profiling
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
- G02B21/002—Scanning microscopes
- G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
- G02B21/008—Details of detection or image processing, including general computer control
- G02B21/0084—Details of detection or image processing, including general computer control time-scale detection, e.g. strobed, ultra-fast, heterodyne detection
Landscapes
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Engineering & Computer Science (AREA)
- Computer Vision & Pattern Recognition (AREA)
- General Engineering & Computer Science (AREA)
- Microscoopes, Condenser (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US59081504P | 2004-07-23 | 2004-07-23 | |
| PCT/IB2005/002067 WO2006008637A1 (en) | 2004-07-23 | 2005-07-19 | Method and apparatus for fluorescent confocal microscopy |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012129410A Division JP2012212155A (ja) | 2004-07-23 | 2012-06-07 | 共焦点蛍光顕微鏡法及び装置 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008507719A true JP2008507719A (ja) | 2008-03-13 |
| JP2008507719A5 JP2008507719A5 (enExample) | 2008-09-04 |
Family
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007522050A Pending JP2008507719A (ja) | 2004-07-23 | 2005-07-19 | 共焦点蛍光顕微鏡法及び装置 |
| JP2012129410A Pending JP2012212155A (ja) | 2004-07-23 | 2012-06-07 | 共焦点蛍光顕微鏡法及び装置 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012129410A Pending JP2012212155A (ja) | 2004-07-23 | 2012-06-07 | 共焦点蛍光顕微鏡法及び装置 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7335898B2 (enExample) |
| EP (1) | EP1787157B1 (enExample) |
| JP (2) | JP2008507719A (enExample) |
| CN (1) | CN101031837B (enExample) |
| AU (1) | AU2005264061B2 (enExample) |
| CA (1) | CA2574343C (enExample) |
| WO (1) | WO2006008637A1 (enExample) |
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| JP2011526001A (ja) * | 2008-06-27 | 2011-09-29 | エコール ポリテクニック | 組織化された材料のナノ構造を探索するための焦点容量の変調を伴うコヒーレント非線形顕微鏡法システム及び方法 |
| JP2013531819A (ja) * | 2010-06-30 | 2013-08-08 | ジーイー・ヘルスケア・バイオサイエンス・コーポレイション | ライン走査式顕微鏡における同期用システム |
| JP2013545989A (ja) * | 2010-12-07 | 2013-12-26 | エコール ポリテクニーク | 試料の化学、生物学または生化学分析に用いる複合技術による結像のシステムおよび方法 |
| JP2014507017A (ja) * | 2011-03-01 | 2014-03-20 | アプライド プレシジョン インコーポレイテッド | レーザビーム選択器 |
| WO2014119451A1 (ja) * | 2013-02-01 | 2014-08-07 | 浜松ホトニクス株式会社 | 画像取得装置及び撮像装置 |
| WO2014175219A1 (ja) * | 2013-04-26 | 2014-10-30 | 浜松ホトニクス株式会社 | 画像取得装置、試料の合焦点情報を取得する方法及びシステム |
| JP2014532197A (ja) * | 2011-09-29 | 2014-12-04 | エフ・イ−・アイ・カンパニー | 顕微鏡デバイス |
| JP2014240888A (ja) * | 2013-06-11 | 2014-12-25 | 浜松ホトニクス株式会社 | 画像取得装置及び画像取得装置のフォーカス方法 |
| JP2014240887A (ja) * | 2013-06-11 | 2014-12-25 | 浜松ホトニクス株式会社 | 画像取得装置及び画像取得装置のフォーカス方法 |
| JP2015087723A (ja) * | 2013-11-01 | 2015-05-07 | 浜松ホトニクス株式会社 | 画像取得装置及び画像取得装置の画像取得方法 |
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| JP2015219521A (ja) * | 2014-05-16 | 2015-12-07 | チャム エンジニアリング カンパニー リミテッド | 観察器およびこれを備えるレーザー処理装置 |
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| JP2018136156A (ja) * | 2017-02-20 | 2018-08-30 | パナソニックＩｐマネジメント株式会社 | 蛍光検出器及びその制御方法 |
| JP2019053036A (ja) * | 2017-07-06 | 2019-04-04 | セントレ ナショナル デテュッド スパティアレＣｅｎｔｒｅ Ｎａｔｉｏｎａｌ Ｄ‘Ｅｔｕｄｅｓ Ｓｐａｔｉａｌｅｓ | 広帯域ハイパースペクトル分光光度計 |
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Also Published As
| Publication number | Publication date |
|---|---|
| CA2574343A1 (en) | 2006-01-26 |
| WO2006008637A1 (en) | 2006-01-26 |
| CN101031837A (zh) | 2007-09-05 |
| CA2574343C (en) | 2012-05-01 |
| EP1787157A1 (en) | 2007-05-23 |
| AU2005264061B2 (en) | 2009-05-21 |
| US20060017001A1 (en) | 2006-01-26 |
| CN101031837B (zh) | 2011-06-15 |
| US7335898B2 (en) | 2008-02-26 |
| AU2005264061A1 (en) | 2006-01-26 |
| JP2012212155A (ja) | 2012-11-01 |
| EP1787157B1 (en) | 2014-09-24 |
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