JP2008505626A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2008505626A5 JP2008505626A5 JP2007519805A JP2007519805A JP2008505626A5 JP 2008505626 A5 JP2008505626 A5 JP 2008505626A5 JP 2007519805 A JP2007519805 A JP 2007519805A JP 2007519805 A JP2007519805 A JP 2007519805A JP 2008505626 A5 JP2008505626 A5 JP 2008505626A5
- Authority
- JP
- Japan
- Prior art keywords
- sequence
- nucleic acid
- repressor activity
- interest
- fragment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 101710197208 Regulatory protein cro Proteins 0.000 claims 26
- 230000000694 effects Effects 0.000 claims 24
- 150000007523 nucleic acids Chemical class 0.000 claims 20
- 108090000623 proteins and genes Proteins 0.000 claims 17
- 239000012634 fragment Substances 0.000 claims 15
- 108020004707 nucleic acids Proteins 0.000 claims 14
- 102000039446 nucleic acids Human genes 0.000 claims 14
- 238000000034 method Methods 0.000 claims 13
- 210000004027 cell Anatomy 0.000 claims 11
- 102000004169 proteins and genes Human genes 0.000 claims 10
- 229920001184 polypeptide Polymers 0.000 claims 7
- 102000004196 processed proteins & peptides Human genes 0.000 claims 7
- 108090000765 processed proteins & peptides Proteins 0.000 claims 7
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 6
- 230000000295 complement effect Effects 0.000 claims 6
- 239000002773 nucleotide Substances 0.000 claims 6
- 125000003729 nucleotide group Chemical group 0.000 claims 6
- 239000003550 marker Substances 0.000 claims 5
- 210000004978 chinese hamster ovary cell Anatomy 0.000 claims 2
- 238000012258 culturing Methods 0.000 claims 2
- 210000004962 mammalian cell Anatomy 0.000 claims 2
- 238000011144 upstream manufacturing Methods 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58700704P | 2004-07-08 | 2004-07-08 | |
| US60/587,007 | 2004-07-08 | ||
| EP2004051405 | 2004-07-08 | ||
| EPPCT/EP2004/051405 | 2004-07-08 | ||
| PCT/EP2005/053251 WO2006005718A2 (en) | 2004-07-08 | 2005-07-07 | Novel sequence for improving expression of nucleic acid |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008505626A JP2008505626A (ja) | 2008-02-28 |
| JP2008505626A5 true JP2008505626A5 (OSRAM) | 2008-07-24 |
| JP4805262B2 JP4805262B2 (ja) | 2011-11-02 |
Family
ID=34971366
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007519805A Expired - Fee Related JP4805262B2 (ja) | 2004-07-08 | 2005-07-07 | 核酸の発現を改善するための新規配列 |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US7825232B2 (OSRAM) |
| JP (1) | JP4805262B2 (OSRAM) |
| KR (1) | KR101188013B1 (OSRAM) |
| CN (1) | CN1981057B (OSRAM) |
| AT (1) | ATE378426T1 (OSRAM) |
| AU (1) | AU2005261699B2 (OSRAM) |
| BR (1) | BRPI0512798A (OSRAM) |
| CA (1) | CA2573022C (OSRAM) |
| DE (1) | DE602005003369T2 (OSRAM) |
| DK (1) | DK1763586T3 (OSRAM) |
| EA (1) | EA011747B1 (OSRAM) |
| ES (1) | ES2296201T3 (OSRAM) |
| IL (1) | IL180531A (OSRAM) |
| MX (1) | MXPA06014553A (OSRAM) |
| NO (1) | NO341862B1 (OSRAM) |
| NZ (1) | NZ551510A (OSRAM) |
| PT (1) | PT1763586E (OSRAM) |
| WO (1) | WO2006005718A2 (OSRAM) |
| ZA (1) | ZA200610470B (OSRAM) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003290453A1 (en) | 2002-12-20 | 2004-07-14 | Chromagenics B.V. | Means and methods for producing a protein through chromatin openers that are capable of rendering chromatin more accessible to transcription factors |
| US20060195935A1 (en) | 2004-11-08 | 2006-08-31 | Chromagenics B.V. | Selection of host cells expressing protein at high levels |
| US8039230B2 (en) | 2004-11-08 | 2011-10-18 | Chromagenics B.V. | Selection of host cells expressing protein at high levels |
| US20100136616A1 (en) * | 2004-11-08 | 2010-06-03 | Chromagenics B.V. | Selection of Host Cells Expressing Protein at High Levels |
| ES2384391T3 (es) | 2004-11-08 | 2012-07-04 | Chromagenics B.V. | Selección de células hospedantes que expresan proteína a altos niveles |
| EA010863B1 (ru) * | 2004-11-08 | 2008-12-30 | Хромагеникс Б.В. | Отбор клеток-хозяев, экспрессирующих белок на высоких уровнях |
| US8999667B2 (en) * | 2004-11-08 | 2015-04-07 | Chromagenics B.V. | Selection of host cells expressing protein at high levels |
| DK2443239T3 (en) | 2009-06-15 | 2016-02-15 | Cellagenics B V | New stringent selection markers |
| WO2011159157A1 (en) | 2010-06-15 | 2011-12-22 | Cellagenics B.V. | Novel intergenic elements for enhancing gene expression |
| DK2611915T3 (da) | 2010-09-01 | 2015-06-22 | Cellagenics B V | Nukleinsyrefragmenter fra en ribosomal proteinpromoter til forstærkning af genekspression |
| CN110484563B (zh) * | 2019-07-25 | 2023-04-07 | 新乡医学院 | 哺乳动物细胞组合表达载体、表达系统、制备方法和应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4500044B2 (ja) * | 2001-07-04 | 2010-07-14 | クロマジェニックス ビー．ブイ． | 遺伝子転写を調節する特性を含むｄｎａ配列及びそのようなｄｎａ配列を検出し且つ使用するための方法 |
| WO2003106684A2 (en) * | 2002-06-14 | 2003-12-24 | Chromagenics B.V. | A method for simultaneous production of multiple proteins; vectors and cells for use therein |
| AU2003290453A1 (en) * | 2002-12-20 | 2004-07-14 | Chromagenics B.V. | Means and methods for producing a protein through chromatin openers that are capable of rendering chromatin more accessible to transcription factors |
-
2005
- 2005-07-07 BR BRPI0512798-0A patent/BRPI0512798A/pt not_active Application Discontinuation
- 2005-07-07 KR KR1020067027165A patent/KR101188013B1/ko not_active Expired - Fee Related
- 2005-07-07 MX MXPA06014553A patent/MXPA06014553A/es active IP Right Grant
- 2005-07-07 US US11/632,012 patent/US7825232B2/en not_active Expired - Fee Related
- 2005-07-07 WO PCT/EP2005/053251 patent/WO2006005718A2/en not_active Ceased
- 2005-07-07 DE DE602005003369T patent/DE602005003369T2/de not_active Expired - Lifetime
- 2005-07-07 PT PT05756870T patent/PT1763586E/pt unknown
- 2005-07-07 DK DK05756870T patent/DK1763586T3/da active
- 2005-07-07 CA CA2573022A patent/CA2573022C/en not_active Expired - Fee Related
- 2005-07-07 AU AU2005261699A patent/AU2005261699B2/en not_active Ceased
- 2005-07-07 ES ES05756870T patent/ES2296201T3/es not_active Expired - Lifetime
- 2005-07-07 NZ NZ551510A patent/NZ551510A/en not_active IP Right Cessation
- 2005-07-07 JP JP2007519805A patent/JP4805262B2/ja not_active Expired - Fee Related
- 2005-07-07 AT AT05756870T patent/ATE378426T1/de active
- 2005-07-07 EA EA200700233A patent/EA011747B1/ru not_active IP Right Cessation
- 2005-07-07 CN CN2005800229700A patent/CN1981057B/zh not_active Expired - Fee Related
-
2006
- 2006-12-13 ZA ZA200610470A patent/ZA200610470B/xx unknown
-
2007
- 2007-01-03 IL IL180531A patent/IL180531A/en active IP Right Grant
- 2007-02-08 NO NO20070757A patent/NO341862B1/no not_active IP Right Cessation
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2020524490A5 (OSRAM) | ||
| JP2019514358A5 (OSRAM) | ||
| JP2011224002A5 (OSRAM) | ||
| JP2005529610A5 (OSRAM) | ||
| JP2009148257A5 (OSRAM) | ||
| JP2019515666A5 (OSRAM) | ||
| JP2008505626A5 (OSRAM) | ||
| JP2010501170A (ja) | 転写を増大させるためのマトリックス付着領域（ｍａｒ）およびその使用 | |
| CN104087610A (zh) | 穿梭质粒载体及其构建方法和应用 | |
| CN102787125A (zh) | 一种构建tale重复序列的方法 | |
| JP2005509420A5 (OSRAM) | ||
| CN112899252B (zh) | 一种高活性转座酶及其应用 | |
| CN102703424A (zh) | 一种重组工程介导的大肠杆菌基因组点突变的方法 | |
| CN110684755A (zh) | 基于进化信息构建嵌合SaCas9用于增强和扩展PAM位点的识别 | |
| JP2008545436A5 (OSRAM) | ||
| CN115850414B (zh) | 小麦抗白粉病基因PmD479及其应用 | |
| RU2377248C2 (ru) | Устойчивые к грибкам растения и их использование | |
| RU2007124369A (ru) | Производство белков | |
| JP4768155B2 (ja) | 鋳型ｄｎａの製造方法及びそれを用いた無細胞タンパク質合成系によるタンパク質の製造方法 | |
| CA2573022A1 (en) | Novel sequence for improving expression of nucleic acid | |
| CN112899238A (zh) | 基于RNA-m6A修饰水平的化合物筛选细胞模型及其构建与应用 | |
| JP2007508012A5 (OSRAM) | ||
| US9803207B2 (en) | Expression vector for production of recombinant proteins in prokaryotic host cells | |
| JP2014516548A5 (OSRAM) | ||
| Zhou et al. | Isoform sequencing provides insight into natural genetic diversity in maize |