JP2008500991A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2008500991A5 JP2008500991A5 JP2007513846A JP2007513846A JP2008500991A5 JP 2008500991 A5 JP2008500991 A5 JP 2008500991A5 JP 2007513846 A JP2007513846 A JP 2007513846A JP 2007513846 A JP2007513846 A JP 2007513846A JP 2008500991 A5 JP2008500991 A5 JP 2008500991A5
- Authority
- JP
- Japan
- Prior art keywords
- bromo
- phenoxy
- carbonyl
- pyrazole
- acetic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0412198A GB0412198D0 (en) | 2004-05-29 | 2004-05-29 | Medicinal use of receptor ligands |
| GB0414196A GB0414196D0 (en) | 2004-06-24 | 2004-06-24 | Medicinal use of receptor ligands |
| GB0424018A GB0424018D0 (en) | 2004-10-29 | 2004-10-29 | Medicinal use of receptor ligands |
| PCT/EP2005/005884 WO2005115382A1 (en) | 2004-05-29 | 2005-05-30 | Crth2 receptor ligands for medicinal uses |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008500991A JP2008500991A (ja) | 2008-01-17 |
| JP2008500991A5 true JP2008500991A5 (https=) | 2008-07-17 |
Family
ID=34993084
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007513846A Ceased JP2008500991A (ja) | 2004-05-29 | 2005-05-30 | 医学的使用のためのcrth2レセプターリガンド |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US8022063B2 (https=) |
| EP (2) | EP1758579A1 (https=) |
| JP (1) | JP2008500991A (https=) |
| KR (1) | KR20070045153A (https=) |
| AU (1) | AU2005247110B2 (https=) |
| BR (1) | BRPI0511676A (https=) |
| CA (1) | CA2568766A1 (https=) |
| CR (1) | CR8838A (https=) |
| EA (1) | EA014729B1 (https=) |
| IL (1) | IL179694A (https=) |
| MX (1) | MXPA06013912A (https=) |
| NO (1) | NO20066048L (https=) |
| NZ (1) | NZ551810A (https=) |
| WO (1) | WO2005115382A1 (https=) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0301010D0 (sv) | 2003-04-07 | 2003-04-07 | Astrazeneca Ab | Novel compounds |
| SA04250253B1 (ar) | 2003-08-21 | 2009-11-10 | استرازينيكا ايه بي | احماض فينوكسي اسيتيك مستبدلة باعتبارها مركبات صيدلانية لعلاج الامراض التنفسية مثل الربو ومرض الانسداد الرئوي المزمن |
| GB0415320D0 (en) | 2004-07-08 | 2004-08-11 | Astrazeneca Ab | Novel compounds |
| GB0418830D0 (en) | 2004-08-24 | 2004-09-22 | Astrazeneca Ab | Novel compounds |
| GB0422057D0 (en) * | 2004-10-05 | 2004-11-03 | Astrazeneca Ab | Novel compounds |
| UY29223A1 (es) * | 2004-11-23 | 2006-06-30 | Astrazeneca Ab | Ácidos fenoxiacéticos sustituidos, composiciones farmacéuticas que los contienen y procesos para su preparación |
| DK1928457T3 (da) * | 2005-09-30 | 2013-02-04 | Pulmagen Therapeutics Asthma Ltd | Quinoliner og deres terapeutiske anvendelse |
| EP1937632A1 (en) | 2005-10-06 | 2008-07-02 | Astra Zeneca AB | Novel compounds |
| TW200745003A (en) | 2005-10-06 | 2007-12-16 | Astrazeneca Ab | Novel compounds |
| WO2007062678A1 (en) * | 2005-11-29 | 2007-06-07 | 7Tm Pharma A/S | Phenoxyacetic acid derivatives as crth2 receptor ligands |
| GB0524428D0 (en) * | 2005-11-30 | 2006-01-11 | 7Tm Pharma As | Medicinal use of receptor ligands |
| PT2069336E (pt) | 2006-09-07 | 2013-03-07 | Actelion Pharmaceuticals Ltd | Derivados de piridin-4-ilo como agentes imunomoduladores |
| PL2069335T3 (pl) | 2006-09-08 | 2013-05-31 | Actelion Pharmaceuticals Ltd | Pochodne pirydyn-3-ylu jako środki immunomodulujące |
| ES2393412T3 (es) | 2006-09-21 | 2012-12-21 | Actelion Pharmaceuticals Ltd. | Derivados de fenilo y su uso como inmunomoduladores |
| WO2008049864A1 (en) * | 2006-10-25 | 2008-05-02 | Neurosearch A/S | Oxadiazole and thiadiazole compounds and their use as nicotinic acetylcholine receptor modulators |
| TW200848036A (en) * | 2006-12-14 | 2008-12-16 | Astellas Pharma Inc | Novel oxycarbonyl compound |
| BRPI0808789A2 (pt) | 2007-03-16 | 2014-08-12 | Actelion Pharmaceuticals Ltd | Compostos e composição farmacêutica de derivados aminopiridina e uso destes |
| UA100983C2 (ru) | 2007-07-05 | 2013-02-25 | Астразенека Аб | Бифенилоксипропановая кислота как модулятор crth2 и интермедиаты |
| PT2195311E (pt) | 2007-08-17 | 2011-05-25 | Actelion Pharmaceuticals Ltd | Derivados de piridina como moduladores do receptor s1p1/edg1 |
| CN104478821B (zh) | 2007-10-04 | 2016-09-28 | 默克雪兰诺有限公司 | 噁二唑二芳基化合物 |
| MX2010003612A (es) | 2007-10-04 | 2010-04-30 | Merck Serono Sa | Derivados de oxadiazol. |
| KR20100092473A (ko) | 2007-11-01 | 2010-08-20 | 액테리온 파마슈티칼 리미티드 | 신규한 피리미딘 유도체 |
| DK2229358T3 (da) | 2007-12-14 | 2011-07-04 | Pulmagen Therapeutics Asthma Ltd | Indoler og deres terapeutiske anvendelse |
| WO2009082398A1 (en) * | 2007-12-21 | 2009-07-02 | University Of Notre Dame Du Lac | Antibacterial compounds and methods of using same |
| CA2715317A1 (en) | 2008-03-07 | 2009-09-11 | Actelion Pharmaceuticals Ltd | Novel aminomethyl benzene derivatives |
| EP2280278A4 (en) | 2008-05-09 | 2015-04-08 | Sysmex Corp | Blood analyzer, blood analysis method and hemolysis |
| US8138208B2 (en) * | 2008-07-15 | 2012-03-20 | Hoffmann-La Roche Inc. | Aminotetrahydroindazoloacetic acids |
| EP2307382B1 (en) * | 2008-07-15 | 2011-12-21 | F. Hoffmann-La Roche AG | Aminotetrahydroindazoloacetic acids |
| WO2010025553A1 (en) * | 2008-09-08 | 2010-03-11 | Merck Frosst Canada Ltd. | Heteroaromatic compounds as inhibitors of stearoyl-coenzyme a delta-9 desaturase |
| SG172383A1 (en) * | 2008-12-25 | 2011-07-28 | Taisho Pharmaceutical Co Ltd | Isoquinoline derivative |
| CA2751260A1 (en) | 2009-02-12 | 2010-08-19 | Stefano Crosignani | Phenoxy acetic acid derivatives |
| CA2767585C (en) | 2009-07-16 | 2017-09-26 | Actelion Pharmaceuticals Ltd | Pyridin-4-yl derivatives |
| JP5731538B2 (ja) * | 2009-12-23 | 2015-06-10 | アイアンウッド ファーマシューティカルズ インコーポレイテッド | Crth2モジュレーター |
| MX2012014667A (es) | 2010-06-23 | 2013-02-15 | Taisho Pharma Co Ltd | Derivado de isoquinolina. |
| CN102958914B (zh) | 2010-07-05 | 2015-05-27 | 埃科特莱茵药品有限公司 | 1-苯基取代的杂环衍生物及其作为前列腺素d2受体调节剂的用途 |
| EP2457900A1 (en) | 2010-11-25 | 2012-05-30 | Almirall, S.A. | New pyrazole derivatives having CRTh2 antagonistic behaviour |
| MA34910B1 (fr) | 2011-01-19 | 2014-02-01 | Actelion Pharmaceuticals Ltd | Dérivés de 2-methoxy-pyridin-4-yl |
| HUE044867T2 (hu) * | 2011-05-12 | 2019-11-28 | Proteostasis Therapeutics Inc | Proteosztázis szabályzók |
| MX336268B (es) | 2011-07-29 | 2016-01-13 | Toyama Chemical Co Ltd | Compuesto de amidina o sal del mismo. |
| SG11201402796SA (en) | 2011-12-16 | 2014-06-27 | Atopix Therapeutics Ltd | Combination of crth2 antagonist and a proton pump inhibitor for the treatment of eosinophilic esophagitis |
| TW201331179A (zh) | 2011-12-21 | 2013-08-01 | Actelion Pharmaceuticals Ltd | 雜環衍生物及其作為前列腺素d2受體調節劑之用途 |
| CA2876808A1 (en) | 2012-07-05 | 2014-01-09 | Actelion Pharmaceuticals Ltd | 1-phenyl-substituted heterocyclyl derivatives and their use as prostaglandin d2 receptor modulators |
| TWI695831B (zh) | 2014-09-13 | 2020-06-11 | 香港商南北兄弟藥業投資有限公司 | Crth2拮抗劑化合物及其用途 |
| AU2015319834A1 (en) | 2014-09-25 | 2017-04-20 | University Of Notre Dame Du Lac | Non-beta lactam antibiotics |
| PH12017502097B1 (en) | 2015-05-20 | 2023-05-05 | Idorsia Pharmaceuticals Ltd | Crystalline form of the compound (s)-3-{4-[5-(2-cyclopentyl-6-methoxy-pyridin-4-yl)-[1,2,4]oxadiazol-3-yl]-2-ethyl-6-methyl-phenoxy}-propane-1,2-diol |
| WO2018049404A1 (en) | 2016-09-12 | 2018-03-15 | University Of Notre Dame Du Lac | Compounds for the treatment of clostridium difficile infection |
| TWI805601B (zh) | 2017-08-11 | 2023-06-21 | 南韓商愛茉莉太平洋股份有限公司 | 醫藥組成物及抑制其形成結晶的方法 |
| AU2018346597B2 (en) | 2017-10-06 | 2023-07-13 | Forma Therapeutics, Inc. | Inhibiting Ubiquitin Specific Peptidase 30 |
| EP3765459A1 (en) | 2018-03-13 | 2021-01-20 | Shire Human Genetic Therapies, Inc. | Substituted imidazopyridines as inhibitors of plasma kallikrein and uses thereof |
| KR102518632B1 (ko) | 2018-04-18 | 2023-04-06 | (주)아모레퍼시픽 | (r)-n-[1-(3,5-다이플루오로-4-메테인설폰일아미노-페닐)-에틸]-3-(2-프로필-6-트라이플루오로메틸-피리딘-3-일)-아크릴아마이드를 함유하는 약학 조성물 |
| JP7449242B2 (ja) | 2018-05-17 | 2024-03-13 | フォーマ セラピューティクス,インコーポレイテッド | ユビキチン特異的ペプチダーゼ30(usp30)阻害剤として有用な縮合二環化合物 |
| JP7530889B2 (ja) | 2018-10-05 | 2024-08-08 | フォーマ セラピューティクス,インコーポレイテッド | ユビキチン特異的プロテアーゼ30(usp30)阻害剤として作用する縮合ピロリン |
| EP4031245A1 (en) | 2019-09-18 | 2022-07-27 | Takeda Pharmaceutical Company Limited | Heteroaryl plasma kallikrein inhibitors |
| DK4031547T3 (da) | 2019-09-18 | 2024-09-09 | Takeda Pharmaceuticals Co | Plasmakallikreininhibitorer og anvendelser deraf |
| JPWO2022138700A1 (https=) * | 2020-12-23 | 2022-06-30 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2104932A1 (en) * | 1970-09-08 | 1972-04-28 | Ferlux | O-hydroxyphenyl pyrazoles - hypocholesterolemics anti inflammatories analgesics etc |
| CZ284157B6 (cs) * | 1992-12-17 | 1998-08-12 | Pfizer Inc. | Pyrazolové a pyrazolopyrimidinové sloučeniny jako takové a pro léčbu chorob a farmaceutické prostředky na jejich bázi |
| AU9002798A (en) | 1997-09-19 | 1999-04-12 | Ono Pharmaceutical Co. Ltd. | Fused or nonfused benzene compounds |
| US6291514B1 (en) * | 1998-02-09 | 2001-09-18 | 3-Dimensional Pharmaceuticals, Inc. | Heteroaryl amidines, methylamidines and guanidines, preparation thereof, and use thereof as protease inhibitors |
| HRP20000724A2 (en) * | 1998-05-05 | 2001-06-30 | Hoffmann La Roche | Pyrazole derivatives as p-38 map kinase inhibitors |
| US6376527B1 (en) * | 1998-05-05 | 2002-04-23 | Syntex (U.S.A.) Llc | Pyrazole derivatives-p38 map kinase inhibitors |
| US6316466B1 (en) * | 1998-05-05 | 2001-11-13 | Syntex (U.S.A.) Llc | Pyrazole derivatives P-38 MAP kinase inhibitors |
| CA2413878A1 (en) * | 2000-06-20 | 2001-12-27 | Atherogenics, Inc. | 1,3-bis-(substituted-phenyl)-2-propen-1-ones and their use to treat vcam-1 mediated disorders |
| AU7705601A (en) * | 2000-07-25 | 2002-02-05 | Merck & Co Inc | N-substituted indoles useful in the treatment of diabetes |
| ATE397925T1 (de) * | 2001-12-18 | 2008-07-15 | Hoffmann La Roche | Cis-imidazoline als mdm2-hemmer |
| SE0200411D0 (sv) | 2002-02-05 | 2002-02-05 | Astrazeneca Ab | Novel use |
| SE0200356D0 (sv) | 2002-02-05 | 2002-02-05 | Astrazeneca Ab | Novel use |
| WO2003097042A1 (en) | 2002-05-16 | 2003-11-27 | Shionogi & Co., Ltd. | Pgd2 receptor antagonist |
| AU2003231509A1 (en) | 2002-05-16 | 2003-12-02 | Shionogi And Co., Ltd. | Compound exhibiting pgd 2 receptor antagonism |
| GB2388540A (en) | 2002-05-17 | 2003-11-19 | Bayer Ag | New use of Ramatroban |
| TW200307542A (en) | 2002-05-30 | 2003-12-16 | Astrazeneca Ab | Novel compounds |
| SE0201635D0 (sv) | 2002-05-30 | 2002-05-30 | Astrazeneca Ab | Novel compounds |
| CN100457730C (zh) * | 2002-08-29 | 2009-02-04 | 默克公司 | 具有抗糖尿病活性的吲哚化合物 |
| SE0301010D0 (sv) * | 2003-04-07 | 2003-04-07 | Astrazeneca Ab | Novel compounds |
| SA04250253B1 (ar) | 2003-08-21 | 2009-11-10 | استرازينيكا ايه بي | احماض فينوكسي اسيتيك مستبدلة باعتبارها مركبات صيدلانية لعلاج الامراض التنفسية مثل الربو ومرض الانسداد الرئوي المزمن |
| WO2007062678A1 (en) * | 2005-11-29 | 2007-06-07 | 7Tm Pharma A/S | Phenoxyacetic acid derivatives as crth2 receptor ligands |
-
2005
- 2005-05-30 EP EP05770220A patent/EP1758579A1/en not_active Withdrawn
- 2005-05-30 AU AU2005247110A patent/AU2005247110B2/en not_active Ceased
- 2005-05-30 NZ NZ551810A patent/NZ551810A/en unknown
- 2005-05-30 BR BRPI0511676-7A patent/BRPI0511676A/pt not_active IP Right Cessation
- 2005-05-30 EP EP10177122A patent/EP2336113A1/en not_active Withdrawn
- 2005-05-30 JP JP2007513846A patent/JP2008500991A/ja not_active Ceased
- 2005-05-30 EA EA200602290A patent/EA014729B1/ru not_active IP Right Cessation
- 2005-05-30 MX MXPA06013912A patent/MXPA06013912A/es not_active Application Discontinuation
- 2005-05-30 KR KR1020067027504A patent/KR20070045153A/ko not_active Ceased
- 2005-05-30 CA CA002568766A patent/CA2568766A1/en not_active Abandoned
- 2005-05-30 WO PCT/EP2005/005884 patent/WO2005115382A1/en not_active Ceased
- 2005-05-30 US US11/597,873 patent/US8022063B2/en not_active Expired - Fee Related
-
2006
- 2006-11-29 IL IL179694A patent/IL179694A/en not_active IP Right Cessation
- 2006-12-22 CR CR8838A patent/CR8838A/es not_active Application Discontinuation
- 2006-12-28 NO NO20066048A patent/NO20066048L/no not_active Application Discontinuation
-
2011
- 2011-06-02 US US13/151,317 patent/US20110269763A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2008500991A5 (https=) | ||
| US4098888A (en) | Thiazolylacetamido cephalosporin type compounds | |
| US4203899A (en) | Thiazolylacetamido compounds | |
| NZ597381A (en) | Thiazolidinedione analogues for the treatment of diabetes and inflammatory diseases | |
| JP2009517417A5 (https=) | ||
| JP2008500991A (ja) | 医学的使用のためのcrth2レセプターリガンド | |
| WO2005040167A1 (en) | Novel diazaspiroalkanes and their use for treatment of ccr8 mediated diseases | |
| JP5734532B2 (ja) | アゾールベンゼン誘導体 | |
| JP2017512779A5 (https=) | ||
| CA2587800A1 (en) | Fused aminopiperidines as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes | |
| CA2522024A1 (en) | Cgrp receptor antagonists | |
| JP2015502387A5 (https=) | ||
| JP2008503447A5 (https=) | ||
| US8399451B2 (en) | Heterocyclic compounds | |
| US4298606A (en) | Thiazolylacetamido compounds | |
| JP2022519239A5 (https=) | ||
| AU2015339091A1 (en) | Amide substituted thiazoles as modulators of RORyT | |
| JP2008516968A5 (https=) | ||
| JP6134072B2 (ja) | キサンチンオキシダーゼ阻害薬 | |
| JP2014503599A5 (https=) | ||
| BRPI0817824B1 (pt) | derivados de (r)-4-(heteroaril) feniletila, composições farmacêuticas e processo para preparação dos mesmos | |
| JPS6133189A (ja) | セファロスポリン誘導体及びその製法 | |
| JP2020502213A5 (https=) | ||
| JP2009007348A5 (https=) | ||
| US4668783A (en) | Thiazolylacetamido cephalosporin compounds |