JP2014503599A5 - - Google Patents
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- Publication number
- JP2014503599A5 JP2014503599A5 JP2013551904A JP2013551904A JP2014503599A5 JP 2014503599 A5 JP2014503599 A5 JP 2014503599A5 JP 2013551904 A JP2013551904 A JP 2013551904A JP 2013551904 A JP2013551904 A JP 2013551904A JP 2014503599 A5 JP2014503599 A5 JP 2014503599A5
- Authority
- JP
- Japan
- Prior art keywords
- octane
- azabicyclo
- oxo
- pyridinecarboxamide
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20110008960 | 2011-01-28 | ||
| KR10-2011-0008960 | 2011-01-28 | ||
| PCT/KR2012/000648 WO2012102580A1 (en) | 2011-01-28 | 2012-01-30 | Pharmaceutical composition comprising pyridone derivatives |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014503599A JP2014503599A (ja) | 2014-02-13 |
| JP2014503599A5 true JP2014503599A5 (https=) | 2014-12-25 |
| JP5921576B2 JP5921576B2 (ja) | 2016-05-24 |
Family
ID=46581019
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013551904A Expired - Fee Related JP5921576B2 (ja) | 2011-01-28 | 2012-01-30 | ピリドン誘導体を含む医薬組成物 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US8716309B2 (https=) |
| EP (1) | EP2668186B1 (https=) |
| JP (1) | JP5921576B2 (https=) |
| KR (1) | KR101925971B1 (https=) |
| CN (1) | CN103328477B (https=) |
| CA (1) | CA2824467C (https=) |
| ES (1) | ES2634204T3 (https=) |
| WO (1) | WO2012102580A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101928505B1 (ko) | 2011-01-28 | 2018-12-12 | 에스케이바이오팜 주식회사 | 피리돈 유도체 및 이를 포함하는 약학적 조성물 |
| AR092742A1 (es) | 2012-10-02 | 2015-04-29 | Intermune Inc | Piridinonas antifibroticas |
| MX382781B (es) | 2014-04-02 | 2025-03-13 | Intermune Inc | Piridinonas anti-fibroticas. |
| WO2016132343A1 (en) * | 2015-02-17 | 2016-08-25 | Mapi Pharma Ltd. | Process and intermediates for the preparation of perampanel |
| UA120571C2 (uk) | 2016-03-22 | 2019-12-26 | Мерк Шарп Енд Дохме Корп. | Алостеричні модулятори нікотинових ацетилхолінових рецепторів |
| US12365651B2 (en) | 2017-07-31 | 2025-07-22 | Washington University | Use of pirfenidone and derivatives for modulation of B lymphocyte activity and organ protection from acute tissue damage |
| MA52482B1 (fr) | 2018-05-01 | 2024-12-31 | Merck Sharp & Dohme Llc | Dérivés de spiropipéridine en tant que modulateurs allostériques des récepteurs nicotiniques de l'acétylcholine |
| CN109293507B (zh) * | 2018-10-12 | 2020-12-18 | 河北科技大学 | 4-甲氧基甲烯基-2-烯戊二酸二甲酯的合成方法及其应用 |
| US12534458B2 (en) | 2019-11-05 | 2026-01-27 | Merck Sharp & Dohme Llc | Spiropiperidine allosteric modulators of nicotinic acetylcholine receptors |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4404138A (en) * | 1982-06-22 | 1983-09-13 | Warner-Lambert Company | 3-[2-(Azabicyclo) ethyl]-1,2,3,4-tetrahydro-5H-[1]benzopyrano[3,4-c]pyridin-5-ones |
| ES2305373T3 (es) * | 1999-01-29 | 2008-11-01 | Abbott Laboratories | Derivados diazabiciclicos como ligandos del receptor nicotinico de la acetilcolina. |
| SE0000540D0 (sv) * | 2000-02-18 | 2000-02-18 | Astrazeneca Ab | New compounds |
| US6569865B2 (en) | 2001-06-01 | 2003-05-27 | Astrazeneca Ab | Spiro 1-azabicyclo[2.2.2]octane-3,2′(3′h)-furo[2,3-b]pyridine |
| JP2005510482A (ja) * | 2001-10-16 | 2005-04-21 | アストラゼネカ・アクチエボラーグ | 線維筋痛症候群の治療方法 |
| FR2834511B1 (fr) | 2002-01-07 | 2004-02-13 | Sanofi Synthelabo | Derives de 5-(pyridin-3-yl)-1-azabicyclo[3.2.1]octane, leur preparation et leur application en therapeutique |
| EP2344636B1 (en) * | 2008-10-09 | 2017-12-06 | Howard Hughes Medical Institute | Novel chimeric ligand-gated ion channels and methods of use thereof |
| US20110262407A1 (en) * | 2008-11-11 | 2011-10-27 | Targacept, Inc. | Treatment with alpha7 selective ligands |
| KR101928505B1 (ko) * | 2011-01-28 | 2018-12-12 | 에스케이바이오팜 주식회사 | 피리돈 유도체 및 이를 포함하는 약학적 조성물 |
-
2012
- 2012-01-27 KR KR1020120008536A patent/KR101925971B1/ko active Active
- 2012-01-30 JP JP2013551904A patent/JP5921576B2/ja not_active Expired - Fee Related
- 2012-01-30 ES ES12740018.2T patent/ES2634204T3/es active Active
- 2012-01-30 EP EP12740018.2A patent/EP2668186B1/en active Active
- 2012-01-30 WO PCT/KR2012/000648 patent/WO2012102580A1/en not_active Ceased
- 2012-01-30 CN CN201280006741.XA patent/CN103328477B/zh active Active
- 2012-01-30 CA CA2824467A patent/CA2824467C/en active Active
- 2012-01-30 US US13/980,819 patent/US8716309B2/en active Active
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