JP2008500366A5 - - Google Patents
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- Publication number
- JP2008500366A5 JP2008500366A5 JP2007515355A JP2007515355A JP2008500366A5 JP 2008500366 A5 JP2008500366 A5 JP 2008500366A5 JP 2007515355 A JP2007515355 A JP 2007515355A JP 2007515355 A JP2007515355 A JP 2007515355A JP 2008500366 A5 JP2008500366 A5 JP 2008500366A5
- Authority
- JP
- Japan
- Prior art keywords
- moiety
- aryl
- heteroaryl
- heterocyclic
- alicyclic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 CC(*)(*C(*)C(C(*)C(C(*)C(C12)O)*(C=CC3)=C)*=C)C(*)C(**)*C13[C@]2N Chemical compound CC(*)(*C(*)C(C(*)C(C(*)C(C12)O)*(C=CC3)=C)*=C)C(*)C(**)*C13[C@]2N 0.000 description 7
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57411404P | 2004-05-25 | 2004-05-25 | |
| US60/574,114 | 2004-05-25 | ||
| PCT/US2005/018603 WO2006001967A2 (en) | 2004-05-25 | 2005-05-25 | Migrastatin analogs in the treatment of cancer |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008136097A Division JP2008273981A (ja) | 2004-05-25 | 2008-05-23 | 癌の処置におけるマイグラスタチンアナログ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008500366A JP2008500366A (ja) | 2008-01-10 |
| JP2008500366A5 true JP2008500366A5 (https=) | 2008-07-10 |
| JP5149001B2 JP5149001B2 (ja) | 2013-02-20 |
Family
ID=35355865
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007515355A Expired - Fee Related JP5149001B2 (ja) | 2004-05-25 | 2005-05-25 | 癌の処置におけるマイグラスタチンアナログ |
| JP2008136097A Pending JP2008273981A (ja) | 2004-05-25 | 2008-05-23 | 癌の処置におけるマイグラスタチンアナログ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008136097A Pending JP2008273981A (ja) | 2004-05-25 | 2008-05-23 | 癌の処置におけるマイグラスタチンアナログ |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US8957056B2 (https=) |
| JP (2) | JP5149001B2 (https=) |
| WO (1) | WO2006001967A2 (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7943800B2 (en) | 2003-03-28 | 2011-05-17 | Sloan-Kettering Institute For Cancer Research | Migrastatin analogs and uses thereof |
| JP5149001B2 (ja) | 2004-05-25 | 2013-02-20 | スローン−ケッタリング・インスティテュート・フォー・キャンサー・リサーチ | 癌の処置におけるマイグラスタチンアナログ |
| US8188141B2 (en) * | 2004-09-23 | 2012-05-29 | Sloan-Kettering Institute For Cancer Research | Isomigrastatin analogs in the treatment of cancer |
| US20100040574A1 (en) * | 2006-05-22 | 2010-02-18 | Xbiotech Inc. | TREATMENT OF CANCER WITH ANTI-IL-1alpha ANTIBODIES |
| US20080312317A1 (en) * | 2007-04-12 | 2008-12-18 | Eisai R&D Management Co., Ltd. | 12 membered-ring macrolactam derivatives |
| CA2707009A1 (en) * | 2007-11-21 | 2009-06-04 | Cornell University | Methods for inhibiting fascin |
| EP2285409B1 (en) | 2008-05-30 | 2016-04-20 | XBiotech, Inc | Il-1 alpha antibodies |
| US20110306563A1 (en) * | 2008-12-17 | 2011-12-15 | Sanofi | Macrolactone derivatives, method for the production thereof and use thereof for the treatment of cancer |
| US9420770B2 (en) | 2009-12-01 | 2016-08-23 | Indiana University Research & Technology Corporation | Methods of modulating thrombocytopenia and modified transgenic pigs |
| EP2582391B1 (en) | 2010-06-18 | 2018-10-03 | XBiotech, Inc | Arthritis treatment |
| KR101910760B1 (ko) | 2010-08-23 | 2018-10-22 | 엑스바이오테크, 인크. | 종양성 질병들에 대한 치료 |
| DK2694107T3 (en) | 2011-04-01 | 2018-12-10 | Xbiotech Inc | TREATMENT OF DERMATOLOGICAL DISORDERS |
| US9724409B2 (en) | 2011-04-01 | 2017-08-08 | Xbiotech, Inc. | Treatment of inflammatory skin disease |
| CA2832439C (en) * | 2011-04-07 | 2017-08-29 | Sloan-Kettering Institute For Cancer Research | Migrastatins and uses thereof |
| WO2013013240A2 (en) * | 2011-07-21 | 2013-01-24 | Theracrine, Inc. | Macrocyclic compounds and related compositons and methods of use |
| CN108404127B (zh) | 2011-09-23 | 2025-12-12 | 埃克斯生物科技公司 | 恶病质治疗 |
| US9545441B2 (en) | 2012-09-18 | 2017-01-17 | Xbiotech, Inc. | Treatment of diabetes |
| SG11201608303QA (en) | 2014-04-04 | 2016-11-29 | Del Mar Pharmaceuticals | Use of dianhydrogalactitol and analogs or derivatives thereof to treat non-small-cell carcinoma of the lung and ovarian cancer |
| EP3582813A4 (en) | 2017-02-16 | 2020-12-30 | XBiotech, Inc | TREATMENT OF SUPPURATIVE HIDRADENITIS |
| CA3095740A1 (en) | 2020-10-07 | 2022-04-07 | Xbiotech Inc. | True human antibody specific for interleukin alpha (il-1a) |
| CA3095679A1 (en) | 2020-10-07 | 2022-04-07 | Xbiotech Inc. | True human antibody specific for interleuken 1 alpha (il-1a) |
| CA3095676A1 (en) | 2020-10-07 | 2022-04-07 | Xbiotech Inc. | True human antibody specific for interleukin 1 alpha (il-1a) |
| CA3095675A1 (en) | 2020-10-07 | 2022-04-07 | Xbiotech Inc. | True human antibody specific for interleukin 1 alpha (il-1a) |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL66434C (https=) | 1946-12-06 | |||
| FR1264032A (fr) | 1960-05-06 | 1961-06-19 | Rhone Poulenc Sa | Acide cycloundecanecarboxylique |
| GB1036084A (en) | 1962-02-23 | 1966-07-13 | Upjohn Co | Oxygenated cycloalkanes and the preparation thereof |
| NL302921A (https=) | 1963-01-21 | |||
| DE2934678A1 (de) | 1979-08-28 | 1981-03-12 | Haarmann & Reimer Gmbh, 3450 Holzminden | Cyclopentadecen-8-on-1, verfahren zu seiner herstellung und seine verwendung als riechstoff |
| DE2934683A1 (de) | 1979-08-28 | 1981-03-12 | Haarmann & Reimer Gmbh, 3450 Holzminden | 3-methyl-cyclohexadecen-5-on-1, verfahren zu seiner herstellung und seine verwendung als riechstoff. |
| US4472435A (en) | 1980-07-31 | 1984-09-18 | Hoffman-La Roche Inc. | Benzophenone derivatives useful in treating heart failure |
| JPS6156146A (ja) | 1984-08-28 | 1986-03-20 | Nippon Mining Co Ltd | 大環状ケトンの製造方法 |
| US4938949A (en) | 1988-09-12 | 1990-07-03 | University Of New York | Treatment of damaged bone marrow and dosage units therefor |
| EP0374445A1 (fr) | 1988-12-23 | 1990-06-27 | Firmenich Sa | Nouveaux composés cycliques oxygénés, leur utilisation à titre d'ingrédients parfumants, procédé pour leur préparation |
| JPH07138257A (ja) | 1993-11-16 | 1995-05-30 | Taisho Pharmaceut Co Ltd | 骨吸収抑制物質br−040及びbr−042 |
| AR043071A1 (es) | 1997-10-31 | 2005-07-20 | Abbott Lab | Uso de macrolidos para el tratamiento del cancer y degeneracion macular y una composicion farmaceutica |
| EP0976714A1 (en) | 1998-07-06 | 2000-02-02 | Quest International B.V. | Addition of ketones to alkenes |
| SG80643A1 (en) | 1998-09-03 | 2001-05-22 | Givaudan Roure Int | Methylcyclotetradec-5-en-1-ones |
| JP2000247949A (ja) * | 1999-02-26 | 2000-09-12 | Eisai Co Ltd | スルホンアミド含有インドール化合物 |
| JP2001078793A (ja) | 1999-09-10 | 2001-03-27 | Nippon Kayaku Co Ltd | 新規生理活性物質の醗酵法による製造法 |
| JP2001081088A (ja) | 1999-09-10 | 2001-03-27 | Nippon Kayaku Co Ltd | 新規生理活性物質nk30424類縁体とそれらの製造法および用途 |
| AU2401401A (en) | 1999-12-22 | 2001-07-03 | Zaidan Hojin Biseibutsu Kagaku Kenkyukai | Migrastatin, process for producing the same and medicinal compositions |
| US6750047B2 (en) | 2000-08-21 | 2004-06-15 | Kosan Biosciences, Inc. | Fermentation and purification of migrastatin and analog |
| US6660306B2 (en) | 2000-10-12 | 2003-12-09 | Mickey L. Peshoff | Wound healing compound |
| TWI312681B (en) | 2001-02-01 | 2009-08-01 | Novel physiologically active substance | |
| JP2004535175A (ja) | 2001-04-26 | 2004-11-25 | エコピア バイオサイエンシーズ インク | ポリケチド生合成用遺伝子及びタンパク質 |
| DE60216362T2 (de) | 2001-06-08 | 2007-09-20 | Takasago International Corp. | Inhibitoren der Melaninherstellung und solche Inhibitoren enthaltende Hautpflegemittel |
| JP2003104967A (ja) * | 2001-09-28 | 2003-04-09 | Takuma Sasaki | ウロキナーゼ産生阻害剤、血管新生阻害剤、癌転移抑制剤および抗腫瘍剤 |
| JP3973889B2 (ja) | 2001-12-04 | 2007-09-12 | 株式会社ジャパンエナジー | 大環状ケトン化合物の製造方法 |
| CN100391753C (zh) | 2002-07-23 | 2008-06-04 | 米其林技术公司 | 具有非直线固定加强件的轮胎 |
| CA2506432A1 (en) | 2002-12-09 | 2004-06-24 | Robert A. Kirken | Methods for selectively inhibiting janus tyrosine kinase 3 (jak3) |
| JP4337815B2 (ja) | 2003-03-19 | 2009-09-30 | 宇部興産株式会社 | ω−シアノアルデヒド化合物の製造法 |
| US20070037783A1 (en) | 2003-03-28 | 2007-02-15 | Xin-Yun Huang | Migrastatin analogs and uses thereof |
| US7943800B2 (en) | 2003-03-28 | 2011-05-17 | Sloan-Kettering Institute For Cancer Research | Migrastatin analogs and uses thereof |
| WO2005019181A1 (en) | 2003-08-19 | 2005-03-03 | Cornell Research Foundation, Inc. | Migrastatin analog cell migration inhibitors |
| JP5149001B2 (ja) | 2004-05-25 | 2013-02-20 | スローン−ケッタリング・インスティテュート・フォー・キャンサー・リサーチ | 癌の処置におけるマイグラスタチンアナログ |
| US8188141B2 (en) | 2004-09-23 | 2012-05-29 | Sloan-Kettering Institute For Cancer Research | Isomigrastatin analogs in the treatment of cancer |
| CA2707009A1 (en) | 2007-11-21 | 2009-06-04 | Cornell University | Methods for inhibiting fascin |
-
2005
- 2005-05-25 JP JP2007515355A patent/JP5149001B2/ja not_active Expired - Fee Related
- 2005-05-25 WO PCT/US2005/018603 patent/WO2006001967A2/en not_active Ceased
- 2005-05-25 US US11/597,678 patent/US8957056B2/en not_active Expired - Fee Related
-
2008
- 2008-05-23 JP JP2008136097A patent/JP2008273981A/ja active Pending
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