JP2007536252A5 - - Google Patents
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- Publication number
- JP2007536252A5 JP2007536252A5 JP2007511571A JP2007511571A JP2007536252A5 JP 2007536252 A5 JP2007536252 A5 JP 2007536252A5 JP 2007511571 A JP2007511571 A JP 2007511571A JP 2007511571 A JP2007511571 A JP 2007511571A JP 2007536252 A5 JP2007536252 A5 JP 2007536252A5
- Authority
- JP
- Japan
- Prior art keywords
- carbonyl
- cyclopropyl
- spiro
- pyrrolidin
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 *C(*)(*)C(N1CC(*)(*)CC1)=O Chemical compound *C(*)(*)C(N1CC(*)(*)CC1)=O 0.000 description 2
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US56927304P | 2004-05-07 | 2004-05-07 | |
| US60/569,273 | 2004-05-07 | ||
| US60205104P | 2004-08-17 | 2004-08-17 | |
| US60/602,051 | 2004-08-17 | ||
| US60279104P | 2004-08-19 | 2004-08-19 | |
| US60/602,791 | 2004-08-19 | ||
| US63880304P | 2004-12-22 | 2004-12-22 | |
| US60/638,803 | 2004-12-22 | ||
| PCT/US2005/015559 WO2005110992A1 (en) | 2004-05-07 | 2005-05-04 | Amido compounds and their use as pharmaceuticals |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013044576A Division JP2013151519A (ja) | 2004-05-07 | 2013-03-06 | アミド化合物およびその医薬としての使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007536252A JP2007536252A (ja) | 2007-12-13 |
| JP2007536252A5 true JP2007536252A5 (https=) | 2008-06-26 |
| JP5265913B2 JP5265913B2 (ja) | 2013-08-14 |
Family
ID=35394113
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007511571A Expired - Lifetime JP5265913B2 (ja) | 2004-05-07 | 2005-05-04 | アミド化合物およびその医薬としての使用 |
| JP2013044576A Pending JP2013151519A (ja) | 2004-05-07 | 2013-03-06 | アミド化合物およびその医薬としての使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013044576A Pending JP2013151519A (ja) | 2004-05-07 | 2013-03-06 | アミド化合物およびその医薬としての使用 |
Country Status (29)
| Country | Link |
|---|---|
| US (7) | US7304081B2 (https=) |
| EP (2) | EP1756063B1 (https=) |
| JP (2) | JP5265913B2 (https=) |
| KR (1) | KR101252227B1 (https=) |
| AU (1) | AU2005243222C1 (https=) |
| BR (1) | BRPI0510736B1 (https=) |
| CA (1) | CA2565238C (https=) |
| CR (1) | CR8702A (https=) |
| CY (1) | CY1116779T1 (https=) |
| DK (1) | DK1756063T3 (https=) |
| EA (1) | EA025359B1 (https=) |
| EC (1) | ECSP066978A (https=) |
| ES (1) | ES2550006T3 (https=) |
| GE (1) | GEP201706611B (https=) |
| HK (1) | HK1218545A1 (https=) |
| HR (1) | HRP20151064T1 (https=) |
| HU (1) | HUE025521T2 (https=) |
| IL (1) | IL179042A (https=) |
| ME (1) | ME02231B (https=) |
| MX (1) | MX340538B (https=) |
| NO (1) | NO340031B1 (https=) |
| NZ (1) | NZ550775A (https=) |
| PL (1) | PL1756063T3 (https=) |
| PT (1) | PT1756063E (https=) |
| RS (1) | RS54236B1 (https=) |
| SG (1) | SG151329A1 (https=) |
| SI (1) | SI1756063T1 (https=) |
| TW (1) | TWI350168B (https=) |
| WO (1) | WO2005110992A1 (https=) |
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| TWI350168B (en) * | 2004-05-07 | 2011-10-11 | Incyte Corp | Amido compounds and their use as pharmaceuticals |
| MXPA06014573A (es) * | 2004-06-24 | 2007-03-12 | Incyte Corp | Compuestos amido y su uso como farmaceuticos. |
| US20050288338A1 (en) * | 2004-06-24 | 2005-12-29 | Wenqing Yao | Amido compounds and their use as pharmaceuticals |
| US20060009491A1 (en) * | 2004-06-24 | 2006-01-12 | Incyte Corporation | Amido compounds and their use as pharmaceuticals |
| US8071624B2 (en) | 2004-06-24 | 2011-12-06 | Incyte Corporation | N-substituted piperidines and their use as pharmaceuticals |
| US7687665B2 (en) * | 2004-06-24 | 2010-03-30 | Incyte Corporation | 2-methylprop anamides and their use as pharmaceuticals |
| SG163518A1 (en) * | 2004-06-24 | 2010-08-30 | Incyte Corp | Amido compounds and their use as pharmaceuticals |
| EP1841738A4 (en) * | 2004-07-29 | 2010-06-02 | Athersys Inc | TRICYCLIC INDENOPYRROLE DERIVATIVES AS MODULATORS OF SEROTONIN RECEPTORS |
| US20060122197A1 (en) * | 2004-08-10 | 2006-06-08 | Wenqing Yao | Amido compounds and their use as pharmaceuticals |
| US8110581B2 (en) | 2004-11-10 | 2012-02-07 | Incyte Corporation | Lactam compounds and their use as pharmaceuticals |
| CA2585797C (en) * | 2004-11-10 | 2015-01-06 | Incyte Corporation | Lactam compounds and their use as pharmaceuticals |
| JP2008520700A (ja) * | 2004-11-18 | 2008-06-19 | インサイト・コーポレイション | 11−βヒドロキシルステロイドデヒドロゲナーゼタイプIの阻害剤およびその使用方法 |
| SG176463A1 (en) | 2005-02-22 | 2011-12-29 | Univ Michigan | Small molecule inhibitors of mdm2 and uses thereof |
| EP1866298A2 (en) * | 2005-03-31 | 2007-12-19 | Takeda San Diego, Inc. | Hydroxysteroid dehydrogenase inhibitors |
| MY144968A (en) | 2005-04-11 | 2011-11-30 | Xenon Pharmaceuticals Inc | Spiro-oxindole compounds and their uses as therapeutic agents |
| MY145694A (en) | 2005-04-11 | 2012-03-30 | Xenon Pharmaceuticals Inc | Spiroheterocyclic compounds and their uses as therapeutic agents |
| DE102005044813A1 (de) | 2005-05-19 | 2007-10-04 | Grünenthal GmbH | Substituierte Spiro-Verbindungen und deren Verwendung zur Herstellung von Arzneimitteln |
| EP1893562A4 (en) * | 2005-06-14 | 2010-04-28 | Merck Frosst Canada Ltd | REVERSIBLE INHIBITORS OF MONOAMINE OXIDASE-A AND -B |
| WO2007038138A2 (en) * | 2005-09-21 | 2007-04-05 | Incyte Corporation | Amido compounds and their use as pharmaceuticals |
| BRPI0616463A2 (pt) | 2005-09-29 | 2011-06-21 | Merck & Co Inc | composto, composição farmacêutica, e, uso de um composto |
| EP1957494A2 (en) | 2005-12-05 | 2008-08-20 | Incyte Corporation | Lactam compounds and methods of using the same |
| WO2007084314A2 (en) * | 2006-01-12 | 2007-07-26 | Incyte Corporation | MODULATORS OF 11-ß HYDROXYL STEROID DEHYDROGENASE TYPE 1, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME |
| BRPI0710479A2 (pt) | 2006-01-18 | 2012-08-14 | Hoffmann La Roche | composto, processo para sua preparaÇço, composiÇço farmacÊutica, uso de um composto e mÉtodo de tratamento de doenÇa ou desosrdem metabàlica. |
| BRPI0707408A2 (pt) * | 2006-01-31 | 2011-05-03 | Incyte Corp | compostos de amido e seu uso como produtos farmacêuticos |
| WO2007092435A2 (en) | 2006-02-07 | 2007-08-16 | Wyeth | 11-beta hsd1 inhibitors |
| WO2007101270A1 (en) * | 2006-03-02 | 2007-09-07 | Incyte Corporation | MODULATORS OF 11-β HYDROXYL STEROID DEHYDROGENASE TYPE 1, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME |
| WO2007103719A2 (en) * | 2006-03-03 | 2007-09-13 | Incyte Corporation | MODULATORS OF 11-β HYDROXYL STEROID DEHYDROGENASE TYPE 1, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME |
| US7834050B2 (en) | 2006-03-29 | 2010-11-16 | Duke University | Small molecule insulin mimetics absent quinones |
| WO2007130898A1 (en) * | 2006-05-01 | 2007-11-15 | Incyte Corporation | TETRASUBSTITUTED UREAS AS MODULATORS OF 11-β HYDROXYL STEROID DEHYDROGENASE TYPE 1 |
| PE20110235A1 (es) | 2006-05-04 | 2011-04-14 | Boehringer Ingelheim Int | Combinaciones farmaceuticas que comprenden linagliptina y metmorfina |
| JP2009537564A (ja) | 2006-05-17 | 2009-10-29 | インサイト・コーポレイション | 11−βヒドロキシルステロイドデヒドロゲナーゼタイプIの複素環阻害剤およびそれを用いる方法 |
| US8222288B2 (en) | 2006-08-30 | 2012-07-17 | The Regents Of The University Of Michigan | Small molecule inhibitors of MDM2 and the uses thereof |
| US7737174B2 (en) | 2006-08-30 | 2010-06-15 | The Regents Of The University Of Michigan | Indole inhibitors of MDM2 and the uses thereof |
| CN101541805A (zh) | 2006-09-15 | 2009-09-23 | 先灵公司 | 用于治疗疼痛和脂代射紊乱的氮杂环丁烷和氮杂环丁酮衍生物 |
| AR062790A1 (es) * | 2006-09-15 | 2008-12-03 | Schering Corp | Derivados de azetidina utiles en el tratamiento del dolor, diabetes y trastornos del metabolismo de los lipidos |
| AU2007294763A1 (en) * | 2006-09-15 | 2008-03-20 | Schering Corporation | Treating pain, diabetes, and lipid metabolism disorders |
| AR063280A1 (es) | 2006-10-12 | 2009-01-21 | Xenon Pharmaceuticals Inc | Uso de compuestos de espiro-oxindol como agentes terapeuticos |
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| US8236789B2 (en) | 2008-08-29 | 2012-08-07 | Kowa Company, Ltd. | 1-adamantyl azetidin-2-one derivatives and drugs containing same |
| CN105218565A (zh) | 2008-10-17 | 2016-01-06 | 泽农医药公司 | 螺羟吲哚化合物及其作为治疗剂的用途 |
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