JP2007534725A5 - - Google Patents
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- JP2007534725A5 JP2007534725A5 JP2007510038A JP2007510038A JP2007534725A5 JP 2007534725 A5 JP2007534725 A5 JP 2007534725A5 JP 2007510038 A JP2007510038 A JP 2007510038A JP 2007510038 A JP2007510038 A JP 2007510038A JP 2007534725 A5 JP2007534725 A5 JP 2007534725A5
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- JP
- Japan
- Prior art keywords
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- agent
- seq
- polypeptide
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- Prior art date
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EPPCT/EP2004/004522 | 2004-04-27 | ||
| EP2004004522 | 2004-04-27 | ||
| PCT/EP2005/051914 WO2005103716A2 (en) | 2004-04-27 | 2005-04-27 | Methods, agents, and compound screening assays for inducing differentiation of undifferentiated mammalian cells into osteoblasts |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007534725A JP2007534725A (ja) | 2007-11-29 |
| JP2007534725A5 true JP2007534725A5 (https=) | 2008-06-05 |
| JP5128273B2 JP5128273B2 (ja) | 2013-01-23 |
Family
ID=34981963
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007510038A Expired - Fee Related JP5128273B2 (ja) | 2004-04-27 | 2005-04-27 | 未分化哺乳動物細胞の分化を骨芽細胞へと誘導するための方法、作用物質、及び化合物スクリーニングアッセイ |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US7615626B2 (https=) |
| EP (3) | EP2214018B1 (https=) |
| JP (1) | JP5128273B2 (https=) |
| CA (1) | CA2562833A1 (https=) |
| ES (1) | ES2427177T3 (https=) |
| MX (1) | MXPA06012162A (https=) |
| WO (1) | WO2005103716A2 (https=) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080193500A1 (en) * | 2007-02-14 | 2008-08-14 | Mckay William F | Effect of LMP-1 overexpression on large and small proteoglycans of the disc |
| WO2008109369A2 (en) * | 2007-03-02 | 2008-09-12 | Mdrna, Inc. | Nucleic acid compounds for inhibiting tnf gene expression and uses thereof |
| WO2008155397A2 (en) * | 2007-06-20 | 2008-12-24 | Galapagos N.V. | Molecular targets and compounds, and methods to identify the same, useful in the treatment of bone and joint degenerative diseases |
| EP2170374A2 (en) * | 2007-07-03 | 2010-04-07 | Andreas Reichert | Method for treating diseases related to mitochondrial dysfunction |
| US8759535B2 (en) | 2010-02-18 | 2014-06-24 | High Point Pharmaceuticals, Llc | Substituted fused imidazole derivatives, pharmaceutical compositions, and methods of use thereof |
| DK2536285T3 (en) | 2010-02-18 | 2018-07-16 | Vtv Therapeutics Llc | Substituted fused imidazole derivatives, pharmaceutical compositions and methods for their use |
| TWI622402B (zh) | 2010-02-24 | 2018-05-01 | 免疫遺傳股份有限公司 | 葉酸受體1抗體類和免疫共軛物類及彼等之用途 |
| BR112013025415B1 (pt) | 2011-04-01 | 2021-03-16 | Immunogen, Inc | uso de um imunoconjugado antirreceptor de folato 1 (folr1) |
| US9200073B2 (en) | 2012-08-31 | 2015-12-01 | Immunogen, Inc. | Diagnostic assays and kits for detection of folate receptor 1 |
| WO2014129550A1 (ja) * | 2013-02-21 | 2014-08-28 | 国立大学法人熊本大学 | 骨分化誘導方法及び骨化促進・抑制分子のスクリーニング方法 |
| JP6247472B2 (ja) * | 2013-08-06 | 2017-12-13 | 日本メナード化粧品株式会社 | 幹細胞の未分化状態維持剤及び増殖促進剤 |
| CN113150145B (zh) | 2013-08-30 | 2025-02-14 | 伊缪诺金公司 | 用于检测叶酸受体1的抗体和测定 |
| JP6411778B2 (ja) * | 2014-06-06 | 2018-10-24 | 日本メナード化粧品株式会社 | 幹細胞の未分化状態維持剤及び増殖促進剤 |
| CN116440279B (zh) | 2015-09-17 | 2026-02-24 | 伊缪诺金公司 | 包含抗folr1免疫缀合物的治疗组合 |
| JP6615589B2 (ja) * | 2015-11-13 | 2019-12-04 | 日本メナード化粧品株式会社 | 幹細胞の未分化状態維持剤及び増殖促進剤 |
| KR20190123256A (ko) * | 2016-07-29 | 2019-10-31 | 로저 엘. 카스파 | 액취증 치료 방법 |
| US11993590B2 (en) | 2016-12-04 | 2024-05-28 | 712 North Inc. | Pyranone compounds useful to modulate OMA1 protease |
| EP3548039B1 (en) | 2016-12-04 | 2023-07-19 | Alavi Khorassani Moghadam, Marcel Victor | Ribavirin for use in the treatment of a mitochondrial disease |
| WO2018138709A1 (en) * | 2017-01-30 | 2018-08-02 | National Research Council Of Canada | Blood-brain barrier transmigrating compounds and uses thereof |
| WO2020117886A1 (en) * | 2018-12-07 | 2020-06-11 | Vtv Therapeutics Llc | Methods of inhibiting osteoclastogenesis and osteoclast activity |
| US20220267781A1 (en) * | 2019-07-26 | 2022-08-25 | Ludwig Institute For Cancer Research Ltd | Immune cells with enhanced cytotoxicity and methods of use thereof |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| US5354844A (en) | 1989-03-16 | 1994-10-11 | Boehringer Ingelheim International Gmbh | Protein-polycation conjugates |
| US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
| US5693622A (en) | 1989-03-21 | 1997-12-02 | Vical Incorporated | Expression of exogenous polynucleotide sequences cardiac muscle of a mammal |
| JPH04365487A (ja) * | 1990-04-11 | 1992-12-17 | Consortium Elektrochem Ind Gmbh | 組換dna−構造体、組換ベクター、トランスゲン動物の乳からの蛋白質の取得法、トランスゲン動物の製法及びトランスゲン動物の乳 |
| US5264618A (en) | 1990-04-19 | 1993-11-23 | Vical, Inc. | Cationic lipids for intracellular delivery of biologically active molecules |
| EP0786522A2 (en) | 1992-07-17 | 1997-07-30 | Ribozyme Pharmaceuticals, Inc. | Enzymatic RNA molecules for treatment of stenotic conditions |
| FR2714830B1 (fr) | 1994-01-10 | 1996-03-22 | Rhone Poulenc Rorer Sa | Composition contenant des acides nucléiques, préparation et utilisations. |
| FR2715847B1 (fr) | 1994-02-08 | 1996-04-12 | Rhone Poulenc Rorer Sa | Composition contenant des acides nucléiques, préparation et utilisations. |
| FR2727679B1 (fr) | 1994-12-05 | 1997-01-03 | Rhone Poulenc Rorer Sa | Nouveaux agents de transfection et leurs applications pharmaceutiques |
| FR2730637B1 (fr) | 1995-02-17 | 1997-03-28 | Rhone Poulenc Rorer Sa | Composition pharmaceutique contenant des acides nucleiques, et ses utilisations |
| JPH11335398A (ja) * | 1998-05-22 | 1999-12-07 | Hoechst Marion Roussel Kk | 新規な骨誘導活性を有する単量体蛋白質およびそれらからなる軟骨・骨疾患の予防および治療薬 |
| US20020192209A1 (en) * | 1997-09-17 | 2002-12-19 | Genentech, Inc. | Methods and compositions for inhibiting neoplastic cell growth |
| US6056559A (en) * | 1997-10-01 | 2000-05-02 | Berg Technology, Inc. | Punched sheet coax header |
| US6506559B1 (en) * | 1997-12-23 | 2003-01-14 | Carnegie Institute Of Washington | Genetic inhibition by double-stranded RNA |
| EP0967284A1 (en) * | 1998-05-28 | 1999-12-29 | Pfizer Limited | Phosphodiesterases |
| AU2400401A (en) * | 1999-12-22 | 2001-07-03 | Tanabe Seiyaku Co., Ltd. | Novel phosphodiesterases and genes thereof |
| US20030108926A1 (en) * | 2000-03-15 | 2003-06-12 | Eos Biotechnology, Inc. | Novel methods of diagnosing colorectal cancer, compositions, and methods of screening for colorectal cancer modulators |
| EP1211313A3 (en) * | 2000-11-01 | 2003-04-23 | Pfizer Limited | Modulation of PDE11A activity |
| US20060121550A1 (en) * | 2000-11-01 | 2006-06-08 | Burslem Martyn F | Modulation of PDE11A activity |
| GB0204227D0 (en) * | 2002-02-22 | 2002-04-10 | Pfizer Ltd | Modulation of pde11a activity |
| US6828473B2 (en) * | 2000-11-01 | 2004-12-07 | Pfizer Inc. | Modulation of PDE11A activity |
| US20030104410A1 (en) * | 2001-03-16 | 2003-06-05 | Affymetrix, Inc. | Human microarray |
| WO2002092000A2 (en) * | 2001-05-11 | 2002-11-21 | Genome Therapeutics Corporation | Hbm variants that modulate bone mass and lipid levels |
| AU2002330714A1 (en) * | 2001-05-30 | 2003-01-02 | Biomedical Center | In silico screening for phenotype-associated expressed sequences |
| CA2456199A1 (en) * | 2001-08-03 | 2003-02-13 | Gene Logic, Inc. | Gene associated with bone disorders |
| US20030198627A1 (en) | 2001-09-01 | 2003-10-23 | Gert-Jan Arts | siRNA knockout assay method and constructs |
| WO2003025176A2 (fr) * | 2001-09-17 | 2003-03-27 | Molecular Engines Laboratories | Sequences impliquees dans les phenomenes de suppression tumorale, reversion tumorale, apoptose et/ou resistance aux virus et leur utilisation comme medicaments |
| EP1546727A2 (en) * | 2002-09-24 | 2005-06-29 | Bayer HealthCare AG | Diagnostics and therapeutics for diseases associated with human phosphodiesterase 11a (pde11a) |
| AU2003295600A1 (en) * | 2002-11-14 | 2004-06-15 | Dharmacon, Inc. | Functional and hyperfunctional sirna |
| WO2004070062A2 (en) * | 2003-02-04 | 2004-08-19 | Wyeth | Compositions and methods for diagnosing and treating cancers |
| WO2004094636A1 (en) | 2003-04-24 | 2004-11-04 | Galapagos Genomics N.V. | Effective sirna knock-down constructs |
| US20060216286A1 (en) * | 2003-04-25 | 2006-09-28 | Yasuaki Ito | Novel screening method |
| WO2004099782A2 (en) * | 2003-05-05 | 2004-11-18 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with g-protein-coupled receptor gpr39 (gpr39) |
| AU2005224614A1 (en) * | 2004-03-12 | 2005-09-29 | Exelixis, Inc. | PDES as modifiers of the IGFR pathway and methods of use |
-
2005
- 2005-04-27 WO PCT/EP2005/051914 patent/WO2005103716A2/en not_active Ceased
- 2005-04-27 EP EP10158238.5A patent/EP2214018B1/en not_active Expired - Lifetime
- 2005-04-27 JP JP2007510038A patent/JP5128273B2/ja not_active Expired - Fee Related
- 2005-04-27 ES ES10158238T patent/ES2427177T3/es not_active Expired - Lifetime
- 2005-04-27 MX MXPA06012162A patent/MXPA06012162A/es active IP Right Grant
- 2005-04-27 CA CA002562833A patent/CA2562833A1/en not_active Abandoned
- 2005-04-27 EP EP10174527A patent/EP2259063B1/en not_active Expired - Lifetime
- 2005-04-27 EP EP05747396A patent/EP1747462A2/en not_active Withdrawn
-
2006
- 2006-10-23 US US11/551,744 patent/US7615626B2/en not_active Expired - Fee Related
-
2009
- 2009-10-30 US US12/609,335 patent/US8318137B2/en not_active Expired - Fee Related
-
2012
- 2012-10-30 US US13/664,027 patent/US8883425B2/en not_active Expired - Fee Related
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