JP2007534725A5 - - Google Patents
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- JP2007534725A5 JP2007534725A5 JP2007510038A JP2007510038A JP2007534725A5 JP 2007534725 A5 JP2007534725 A5 JP 2007534725A5 JP 2007510038 A JP2007510038 A JP 2007510038A JP 2007510038 A JP2007510038 A JP 2007510038A JP 2007534725 A5 JP2007534725 A5 JP 2007534725A5
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- JP
- Japan
- Prior art keywords
- group
- agent
- seq
- polypeptide
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP2004004522 | 2004-04-27 | ||
| EPPCT/EP2004/004522 | 2004-04-27 | ||
| PCT/EP2005/051914 WO2005103716A2 (en) | 2004-04-27 | 2005-04-27 | Methods, agents, and compound screening assays for inducing differentiation of undifferentiated mammalian cells into osteoblasts |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007534725A JP2007534725A (ja) | 2007-11-29 |
| JP2007534725A5 true JP2007534725A5 (https=) | 2008-06-05 |
| JP5128273B2 JP5128273B2 (ja) | 2013-01-23 |
Family
ID=34981963
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007510038A Expired - Fee Related JP5128273B2 (ja) | 2004-04-27 | 2005-04-27 | 未分化哺乳動物細胞の分化を骨芽細胞へと誘導するための方法、作用物質、及び化合物スクリーニングアッセイ |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US7615626B2 (https=) |
| EP (3) | EP2259063B1 (https=) |
| JP (1) | JP5128273B2 (https=) |
| CA (1) | CA2562833A1 (https=) |
| ES (1) | ES2427177T3 (https=) |
| MX (1) | MXPA06012162A (https=) |
| WO (1) | WO2005103716A2 (https=) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080193500A1 (en) * | 2007-02-14 | 2008-08-14 | Mckay William F | Effect of LMP-1 overexpression on large and small proteoglycans of the disc |
| WO2008109369A2 (en) * | 2007-03-02 | 2008-09-12 | Mdrna, Inc. | Nucleic acid compounds for inhibiting tnf gene expression and uses thereof |
| EP2565649B1 (en) * | 2007-06-20 | 2015-04-15 | Galapagos N.V. | Molecular targets and compounds, and methods to identify the same, useful in the treatment of bone and joint degenerative diseases |
| US20100209436A1 (en) * | 2007-07-03 | 2010-08-19 | Andreas Reichert | Method for treating diseases related to mitochondrial dysfunction |
| US8759535B2 (en) | 2010-02-18 | 2014-06-24 | High Point Pharmaceuticals, Llc | Substituted fused imidazole derivatives, pharmaceutical compositions, and methods of use thereof |
| WO2011103018A1 (en) | 2010-02-18 | 2011-08-25 | High Point Pharmaceuticals, Llc | Substituted fused imidazole derivatives, pharmaceutical compositions, and methods of use thereof |
| CN103037900B (zh) | 2010-02-24 | 2016-04-06 | 伊缪诺金公司 | 叶酸受体1抗体与免疫缀合物以及其用途 |
| IL281714B2 (en) | 2011-04-01 | 2023-11-01 | Immunogen Inc | Methods for increasing the effectiveness of FOLR1 cancer therapy |
| HUE049693T2 (hu) | 2012-08-31 | 2020-10-28 | Immunogen Inc | Diagnosztikai ASSAY-k és készletek a folát receptor 1 kimutatására |
| JP6464529B2 (ja) * | 2013-02-21 | 2019-02-06 | 国立大学法人 熊本大学 | 骨分化誘導方法及び骨化促進・抑制分子のスクリーニング方法 |
| JP6247472B2 (ja) * | 2013-08-06 | 2017-12-13 | 日本メナード化粧品株式会社 | 幹細胞の未分化状態維持剤及び増殖促進剤 |
| AU2014312086B2 (en) | 2013-08-30 | 2020-03-12 | Immunogen, Inc. | Antibodies and assays for detection of folate receptor 1 |
| JP6411778B2 (ja) * | 2014-06-06 | 2018-10-24 | 日本メナード化粧品株式会社 | 幹細胞の未分化状態維持剤及び増殖促進剤 |
| AU2016323968B2 (en) | 2015-09-17 | 2023-07-06 | Immunogen, Inc. | Therapeutic combinations comprising anti-FOLR1 immunoconjugates |
| JP6615589B2 (ja) * | 2015-11-13 | 2019-12-04 | 日本メナード化粧品株式会社 | 幹細胞の未分化状態維持剤及び増殖促進剤 |
| US20210301289A1 (en) * | 2016-07-29 | 2021-09-30 | Roger L. Kaspar | Methods of treating osmidrosis |
| US11993590B2 (en) | 2016-12-04 | 2024-05-28 | 712 North Inc. | Pyranone compounds useful to modulate OMA1 protease |
| WO2018102672A1 (en) | 2016-12-04 | 2018-06-07 | Alavi Khorassani Moghadam Marcel Victor | Methods for treating diseases related to mitochondrial stress |
| KR20240095466A (ko) * | 2017-01-30 | 2024-06-25 | 내션얼 리서치 카운슬 오브 캐나다 | 혈액-뇌 장벽을 관통이동하는 화합물 및 이의 용도 |
| WO2020117886A1 (en) * | 2018-12-07 | 2020-06-11 | Vtv Therapeutics Llc | Methods of inhibiting osteoclastogenesis and osteoclast activity |
| WO2021021631A1 (en) * | 2019-07-26 | 2021-02-04 | Ludwig Institute For Cancer Research Ltd | Immune cells with enhanced cytotoxicity and methods of use thereof |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| US5354844A (en) | 1989-03-16 | 1994-10-11 | Boehringer Ingelheim International Gmbh | Protein-polycation conjugates |
| US5693622A (en) | 1989-03-21 | 1997-12-02 | Vical Incorporated | Expression of exogenous polynucleotide sequences cardiac muscle of a mammal |
| US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
| JPH04365487A (ja) * | 1990-04-11 | 1992-12-17 | Consortium Elektrochem Ind Gmbh | 組換ｄｎａ−構造体、組換ベクター、トランスゲン動物の乳からの蛋白質の取得法、トランスゲン動物の製法及びトランスゲン動物の乳 |
| US5264618A (en) | 1990-04-19 | 1993-11-23 | Vical, Inc. | Cationic lipids for intracellular delivery of biologically active molecules |
| WO1994002595A1 (en) | 1992-07-17 | 1994-02-03 | Ribozyme Pharmaceuticals, Inc. | Method and reagent for treatment of animal diseases |
| FR2714830B1 (fr) | 1994-01-10 | 1996-03-22 | Rhone Poulenc Rorer Sa | Composition contenant des acides nucléiques, préparation et utilisations. |
| FR2715847B1 (fr) | 1994-02-08 | 1996-04-12 | Rhone Poulenc Rorer Sa | Composition contenant des acides nucléiques, préparation et utilisations. |
| FR2727679B1 (fr) | 1994-12-05 | 1997-01-03 | Rhone Poulenc Rorer Sa | Nouveaux agents de transfection et leurs applications pharmaceutiques |
| FR2730637B1 (fr) | 1995-02-17 | 1997-03-28 | Rhone Poulenc Rorer Sa | Composition pharmaceutique contenant des acides nucleiques, et ses utilisations |
| JPH11335398A (ja) * | 1998-05-22 | 1999-12-07 | Hoechst Marion Roussel Kk | 新規な骨誘導活性を有する単量体蛋白質およびそれらからなる軟骨・骨疾患の予防および治療薬 |
| US20020192209A1 (en) * | 1997-09-17 | 2002-12-19 | Genentech, Inc. | Methods and compositions for inhibiting neoplastic cell growth |
| US6056559A (en) * | 1997-10-01 | 2000-05-02 | Berg Technology, Inc. | Punched sheet coax header |
| US6506559B1 (en) * | 1997-12-23 | 2003-01-14 | Carnegie Institute Of Washington | Genetic inhibition by double-stranded RNA |
| EP0967284A1 (en) * | 1998-05-28 | 1999-12-29 | Pfizer Limited | Phosphodiesterases |
| WO2001046436A1 (fr) * | 1999-12-22 | 2001-06-28 | Tanabe Seiyaku Co., Ltd. | Nouvelles phosphodiesterases et leurs genes |
| US20030108926A1 (en) * | 2000-03-15 | 2003-06-12 | Eos Biotechnology, Inc. | Novel methods of diagnosing colorectal cancer, compositions, and methods of screening for colorectal cancer modulators |
| EP1211313A3 (en) * | 2000-11-01 | 2003-04-23 | Pfizer Limited | Modulation of PDE11A activity |
| US20060121550A1 (en) * | 2000-11-01 | 2006-06-08 | Burslem Martyn F | Modulation of PDE11A activity |
| US6828473B2 (en) * | 2000-11-01 | 2004-12-07 | Pfizer Inc. | Modulation of PDE11A activity |
| GB0204227D0 (en) * | 2002-02-22 | 2002-04-10 | Pfizer Ltd | Modulation of pde11a activity |
| US20030104410A1 (en) * | 2001-03-16 | 2003-06-05 | Affymetrix, Inc. | Human microarray |
| JP2004537289A (ja) * | 2001-05-11 | 2004-12-16 | ゲノム セラピューティックス コーポレーション | 骨量および脂質レベルを調整するｈｂｍ変異型 |
| AU2002330714A1 (en) * | 2001-05-30 | 2003-01-02 | Biomedical Center | In silico screening for phenotype-associated expressed sequences |
| WO2003012070A2 (en) * | 2001-08-03 | 2003-02-13 | Gene Logic, Inc. | Gene associated with bone disorders |
| US20030198627A1 (en) | 2001-09-01 | 2003-10-23 | Gert-Jan Arts | siRNA knockout assay method and constructs |
| WO2003025176A2 (fr) * | 2001-09-17 | 2003-03-27 | Molecular Engines Laboratories | Sequences impliquees dans les phenomenes de suppression tumorale, reversion tumorale, apoptose et/ou resistance aux virus et leur utilisation comme medicaments |
| EP1546727A2 (en) * | 2002-09-24 | 2005-06-29 | Bayer HealthCare AG | Diagnostics and therapeutics for diseases associated with human phosphodiesterase 11a (pde11a) |
| EP2305812A3 (en) * | 2002-11-14 | 2012-06-06 | Dharmacon, Inc. | Fuctional and hyperfunctional sirna |
| WO2004070062A2 (en) * | 2003-02-04 | 2004-08-19 | Wyeth | Compositions and methods for diagnosing and treating cancers |
| WO2004094636A1 (en) * | 2003-04-24 | 2004-11-04 | Galapagos Genomics N.V. | Effective sirna knock-down constructs |
| WO2004097411A1 (ja) * | 2003-04-25 | 2004-11-11 | Takeda Pharmaceutical Company Limited | 新規スクリーニング方法 |
| EP1623230A2 (en) * | 2003-05-05 | 2006-02-08 | Bayer HealthCare AG | Diagnostics and therapeutics for diseases associated with g-protein-coupled receptor gpr39 (gpr39) |
| JP2007528734A (ja) * | 2004-03-12 | 2007-10-18 | エクセリクシス， インク． | Ｉｇｆｒ経路のモディファイヤーとしてのｐｄｅ及び使用方法 |
-
2005
- 2005-04-27 CA CA002562833A patent/CA2562833A1/en not_active Abandoned
- 2005-04-27 WO PCT/EP2005/051914 patent/WO2005103716A2/en not_active Ceased
- 2005-04-27 EP EP10174527A patent/EP2259063B1/en not_active Expired - Lifetime
- 2005-04-27 MX MXPA06012162A patent/MXPA06012162A/es active IP Right Grant
- 2005-04-27 EP EP10158238.5A patent/EP2214018B1/en not_active Expired - Lifetime
- 2005-04-27 JP JP2007510038A patent/JP5128273B2/ja not_active Expired - Fee Related
- 2005-04-27 EP EP05747396A patent/EP1747462A2/en not_active Withdrawn
- 2005-04-27 ES ES10158238T patent/ES2427177T3/es not_active Expired - Lifetime
-
2006
- 2006-10-23 US US11/551,744 patent/US7615626B2/en not_active Expired - Fee Related
-
2009
- 2009-10-30 US US12/609,335 patent/US8318137B2/en not_active Expired - Fee Related
-
2012
- 2012-10-30 US US13/664,027 patent/US8883425B2/en not_active Expired - Fee Related
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