JP2008502355A5 - - Google Patents

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Publication number
JP2008502355A5
JP2008502355A5 JP2007526437A JP2007526437A JP2008502355A5 JP 2008502355 A5 JP2008502355 A5 JP 2008502355A5 JP 2007526437 A JP2007526437 A JP 2007526437A JP 2007526437 A JP2007526437 A JP 2007526437A JP 2008502355 A5 JP2008502355 A5 JP 2008502355A5
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JP
Japan
Prior art keywords
agent
group
polypeptide
ecm
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2007526437A
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English (en)
Japanese (ja)
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JP2008502355A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/EP2005/052754 external-priority patent/WO2005121778A2/en
Publication of JP2008502355A publication Critical patent/JP2008502355A/ja
Publication of JP2008502355A5 publication Critical patent/JP2008502355A5/ja
Pending legal-status Critical Current

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JP2007526437A 2004-06-14 2005-06-14 変性性及び炎症性疾患の治療に役立つ同定方法及び化合物 Pending JP2008502355A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57930704P 2004-06-14 2004-06-14
PCT/EP2005/052754 WO2005121778A2 (en) 2004-06-14 2005-06-14 Methods for identification, and compounds useful for the treatment of degenerative & inflammatory diseases

Publications (2)

Publication Number Publication Date
JP2008502355A JP2008502355A (ja) 2008-01-31
JP2008502355A5 true JP2008502355A5 (https=) 2009-04-30

Family

ID=35503767

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007526437A Pending JP2008502355A (ja) 2004-06-14 2005-06-14 変性性及び炎症性疾患の治療に役立つ同定方法及び化合物

Country Status (7)

Country Link
US (3) US7306923B2 (https=)
EP (4) EP2256198A1 (https=)
JP (1) JP2008502355A (https=)
AT (1) ATE534736T1 (https=)
CA (1) CA2569511A1 (https=)
MX (1) MXPA06014577A (https=)
WO (1) WO2005121778A2 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7485468B2 (en) * 2004-10-15 2009-02-03 Galapagos Bv Molecular targets and compounds, and methods to identify the same, useful in the treatment of joint degenerative and inflammatory diseases
CN103173401A (zh) * 2005-12-22 2013-06-26 简·恩尼斯 来自冷冻的脐带组织的活细胞
EP2565649B1 (en) 2007-06-20 2015-04-15 Galapagos N.V. Molecular targets and compounds, and methods to identify the same, useful in the treatment of bone and joint degenerative diseases
KR20100065190A (ko) 2007-09-14 2010-06-15 닛토덴코 가부시키가이샤 약물 담체
US8450397B2 (en) * 2007-09-25 2013-05-28 Dunlop Sports Co. Ltd. Golf ball
DE102007059839A1 (de) 2007-12-11 2009-06-25 Harald Dipl.-Ing. Feuerherm Schlauchförmiger Vorformling und Herstellung blasgeformter Teile und Verfahren sowie Vorrichtung zur Herstellung des Vorformlings
KR101594202B1 (ko) * 2008-09-24 2016-02-15 텔 하쇼머 메디컬 리서치 인프라스트럭쳐 앤드 서비시스 리미티드. 세포 유착 방지를 위한 펩티드와 조성물 및 그것의 사용 방법
US11174299B2 (en) 2008-12-29 2021-11-16 Dispersebio Ltd. Peptides and compositions for prevention of cell adhesion and methods of using same
EP2376528B1 (en) * 2008-12-29 2014-11-26 Tel Hashomer Medical Research, Infrastructure And Services Ltd. Peptides and compositions for prevention of cell adhesion and methods of using same
AU2015224504B2 (en) * 2008-12-29 2018-02-22 Tel Hashomer Medical Research, Infrastructure And Services Ltd Peptides and compositions for prevention of cell adhesion and methods of using same
US8663930B2 (en) * 2009-04-01 2014-03-04 Galapagos Nv Methods and means for treatment of osteoarthritis
EP2812028A4 (en) 2012-02-07 2016-01-06 Jolla Inst Allergy Immunolog EPITOPES OF ALLERGENIC PROTEINS AND METHOD AND USE TO IMMUNE REACTION MODULATION
WO2014153118A1 (en) * 2013-03-14 2014-09-25 The Board Of Trustees Of The Leland Stanford Junior University Treatment of diseases and conditions associated with dysregulation of mammalian target of rapamycin complex 1 (mtorc1)
CA3073406A1 (en) * 2017-09-13 2019-03-21 Alexera Ab Methods for identifying therapeutic agents which interact with stk24
JP2023511280A (ja) * 2020-01-14 2023-03-17 ザ・トラスティーズ・オブ・コロンビア・ユニバーシティ・イン・ザ・シティ・オブ・ニューヨーク 内因性の脱ユビキチン化酵素をリダイレクトすることによる標的化されたタンパク質の安定化のための組成物及び方法

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
US5354844A (en) 1989-03-16 1994-10-11 Boehringer Ingelheim International Gmbh Protein-polycation conjugates
US5703055A (en) 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
US5693622A (en) 1989-03-21 1997-12-02 Vical Incorporated Expression of exogenous polynucleotide sequences cardiac muscle of a mammal
US5264618A (en) 1990-04-19 1993-11-23 Vical, Inc. Cationic lipids for intracellular delivery of biologically active molecules
WO1994002595A1 (en) 1992-07-17 1994-02-03 Ribozyme Pharmaceuticals, Inc. Method and reagent for treatment of animal diseases
FR2714830B1 (fr) 1994-01-10 1996-03-22 Rhone Poulenc Rorer Sa Composition contenant des acides nucléiques, préparation et utilisations.
FR2715847B1 (fr) 1994-02-08 1996-04-12 Rhone Poulenc Rorer Sa Composition contenant des acides nucléiques, préparation et utilisations.
FR2727679B1 (fr) 1994-12-05 1997-01-03 Rhone Poulenc Rorer Sa Nouveaux agents de transfection et leurs applications pharmaceutiques
FR2730637B1 (fr) 1995-02-17 1997-03-28 Rhone Poulenc Rorer Sa Composition pharmaceutique contenant des acides nucleiques, et ses utilisations
WO2000014250A1 (en) 1998-09-09 2000-03-16 The Board Of Regents Of The University Of Oklahoma Tyrosylprotein sulfotransferase polypeptides and polynucleotides
AU2475899A (en) 1998-01-29 1999-08-16 Board Of Regents Of The University Of Oklahoma, The Tyrosylprotein sulfotransferase polypeptides and polynucleotides
ATE346147T1 (de) * 1998-02-13 2006-12-15 Wistar Inst Zusammensetzungen und methoden zur wundheilung
US6413776B1 (en) 1998-06-12 2002-07-02 Galapagos Geonomics N.V. High throughput screening of gene function using adenoviral libraries for functional genomics applications
US20020151681A1 (en) * 1999-03-12 2002-10-17 Rosen Craig A. Nucleic acids, proteins and antibodies
US20050112118A1 (en) * 1999-12-02 2005-05-26 Myriad Genetics, Incorporated Compositions and methods for treating inflammatory disorders
US7332337B2 (en) 2000-05-16 2008-02-19 Galapagos Nv Viral vectors having tissue tropism for T-lymphocytes, B- and mast cells
DE60138403D1 (de) 2000-09-26 2009-05-28 Crucell Holland Bv Adenovirale vektoren für die übertragung von genen in zellen der skelettmuskulatur oder myoblasten
US20020132823A1 (en) 2001-01-17 2002-09-19 Jiahuai Han Assay method
AU2002253104A1 (en) 2001-03-07 2002-09-19 Galapagos Genomics B.V. Adenoviral library assay for e2f regulatory genes and methods and compositions for screening compounds
US6537780B2 (en) 2001-03-28 2003-03-25 Applera Corporation Isolated nucleic acid molecules encoding transferase enzymes
US6426221B1 (en) * 2001-08-01 2002-07-30 Isis Pharmaceuticals, Inc. Antisense modulation of RIP2 expression
US20030198627A1 (en) 2001-09-01 2003-10-23 Gert-Jan Arts siRNA knockout assay method and constructs
US20030157082A1 (en) * 2002-01-31 2003-08-21 Millennium Pharmaceuticals, Inc. Methods and compositions for treating cancer using 140, 1470, 1686, 2089, 2427, 3702, 5891, 6428, 7181, 7660, 25641, 69583, 49863, 8897, 1682, 17667, 9235, 3703, 14171, 10359, 1660, 1450, 18894, 2088, 32427, 2160, 9252, 9389, 1642, 85269, 10297, 1584, 9525, 14124, 4469, 8990, 2100, 9288, 64698, 10480,20893, 33230,1586, 9943, 16334, 68862, 9011, 14031, 6178, 21225, 1420, 32236, 2099, 2150, 26583, 2784, 8941, 9811, 27444, 50566 or 66428 molecules
WO2004024097A2 (en) * 2002-09-16 2004-03-25 Genentech, Inc. Compositions and methods for the treatment of immune related diseases
AU2003286711A1 (en) 2002-10-25 2004-05-13 Vertex Pharmaceuticals Incorporated Indazolinone compositions useful as kinase inhibitors
CA2503390A1 (en) * 2002-11-01 2004-05-21 Genentech, Inc. Compositions and methods for the treatment of immune related diseases
JP2006518590A (ja) * 2003-01-23 2006-08-17 アイルクス セラピューティクス リミテッド アポトーシスに関与するキナーゼおよびgpcr
JP2006524497A (ja) * 2003-04-18 2006-11-02 ノバルティス アクチエンゲゼルシャフト 骨関節炎のための高処理量機能的ゲノムスクリーニング法
WO2004094636A1 (en) 2003-04-24 2004-11-04 Galapagos Genomics N.V. Effective sirna knock-down constructs
DE10328033A1 (de) 2003-06-19 2005-01-05 Bläß, Stefan, Dr. Verfahren und ArthritisChip zur Diagnostik, Verlaufskontrolle sowie zur Charakterisierung der rheumatoiden Arthritis und der Osteoarthrose
CA2533803A1 (en) * 2003-07-29 2005-02-10 Bristol-Myers Squibb Company Biomarkers of cyclin-dependent kinase modulation
US7485468B2 (en) * 2004-10-15 2009-02-03 Galapagos Bv Molecular targets and compounds, and methods to identify the same, useful in the treatment of joint degenerative and inflammatory diseases

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