JP2007530624A - 月見草(OenotheraBiennis)の天然油(=OleumOenotherae)および極限環境微生物から生じるオスモライトを含有する、皮膚に使用するための局所製剤 - Google Patents
月見草(OenotheraBiennis)の天然油(=OleumOenotherae)および極限環境微生物から生じるオスモライトを含有する、皮膚に使用するための局所製剤 Download PDFInfo
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- JP2007530624A JP2007530624A JP2007505492A JP2007505492A JP2007530624A JP 2007530624 A JP2007530624 A JP 2007530624A JP 2007505492 A JP2007505492 A JP 2007505492A JP 2007505492 A JP2007505492 A JP 2007505492A JP 2007530624 A JP2007530624 A JP 2007530624A
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- A—HUMAN NECESSITIES
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- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/007—Preparations for dry skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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Abstract
Description
Lippert,K.,Galinski,E.A.(1994),Appl.Microbiol.Biotech.37,61-65 Louis, P., Truper, H.G., Galinski, E.A.(1994), Appl. Microbiol. Biotech. 41, 684-688 Ramos, Raven, Sharp, Bartolucci, Rossi, Cannio, Lebbink, v.d. Oost, de Vos, Santos(1997), Appl.Environm.Microbiol.63,4020-4025 Da Costa,Santos,Galinski(1998),Adv.In Biochemical Engineering Biotechnology,61,117-153
高温(室温、25℃)での月見草の油の安定性は、Y-リノレン酸含量および月見草の油の純度に大きく依存する。グリセロールリン酸の0.1%(重量パーセント)を月見草の油の製剤に加えた後、ジグリセロールリン酸を含有しないチェック製剤と比較して、5日間の改善された月見草の油の保存安定性が見られた。製剤の安定性は、月見草の油の悪臭の最初の発生に基づいて評価した。
1時間以内に70℃まで温度を上げ、月見草の油を、ヒドロペルオキシド形成により素早く不安定化/変性させる。この高反応性の分子は、次にポリマー(樹脂化、乾燥)および悪臭を生じる低分子残留物質を形成しうる。5重量%濃度のオスモライトマンノシルグリセレートおよびマンノシルグリセラミドの50:50混合物は、24時間のタイムスパンにより70℃の温度で酸化的変化に対する月見草の油の耐性を強める。50%マンノシルグリセレート−マンノシルグリセラミド混合物の存在下で、悪臭は、70℃で24時間のインキュベート後に気付かれるのみである。したがって、マンノシルグリセレート−マンノシルグリセラミド混合物の使用により、例えば、月見草の油および月見草の油を含有する産物の処理および保存特性が著しく改良できる。
Claims (19)
- 極限環境微生物(extremophilic microorganism)から生じるオスモライト(osmolyte)および不飽和脂肪酸を含有する天然油および脂肪を含む製剤であって、前記製剤が、該製剤の全重量に基づいて少なくとも1種類のオスモライトを0.01-50重量%含有することを特徴とする製剤。
- 前記製剤が、0.05-10重量%のオスモライトを含有することを特徴とする請求項1記載の製剤。
- 前記製剤が、0.01-50重量%の天然油および脂肪を含有することを特徴とする請求項1または2記載の製剤。
- 前記製剤が、0.05-10重量%の天然油および脂肪を含有することを特徴とする請求項3記載の製剤。
- 前記製剤が、月見草の油(Oleum Oenotherae)を含有することを特徴とする請求項1から4いずれか1項記載の製剤。
- エクトイン(ectoine)、ヒドロキシエクトイン、cDPG、DGP、フィロイン(firoin)、フィロインAおよび/またはジイノシトールリン酸がオスモライトとして使用されることを特徴とする請求項1から5いずれか1項記載の製剤。
- 皮膚への化粧用途のための請求項1から6いずれか1項記載の製剤。
- 前記製剤が、溶液、懸濁液、エマルジョン、ペースト、軟膏、ゲル、クリーム、ローション、パウダー、石鹸、界面活性剤含有洗浄剤、オイル、リップスティック、マスカラ、アイライナー、アイシャドウ、口紅、粉末、エマルジョンおよびワックス化粧品、日焼け止め剤、日焼け前および後の処理剤、ヘアートニック、絆創膏、包帯またはスプレーの形態で供給されることを特徴とする請求項7記載の化粧品製剤。
- 不飽和脂肪酸の安定化および/または保存のための、極限環境微生物から生じるオスモライトの使用方法。
- 前記利用されるオスモライトが、製剤全体に対して0.01-50重量%の量で存在することを特徴とする請求項9記載の方法。
- 前記製剤が、0.05-10重量%のオスモライトを含有することを特徴とする請求項9または10記載の方法。
- エクトイン、ヒドロキシエクトイン、cDPG、DGP、フィロイン、フィロインAおよび/またはジイノシトールリン酸がオスモライトとして使用されることを特徴とする請求項9から11いずれか1項記載の方法。
- 月見草の油(Oleum Oenotherae)の安定化のための、請求項9から12いずれか1項記載の方法。
- 化粧および皮膚の分野での局所使用のための製剤を産生するための、極限環境微生物から生じるオスモライトの使用方法。
- 非常に乾燥し、炎症を起こし、鱗状の、問題のある皮膚の手入れおよびケアのため、アトピー性皮膚炎、乾癬および他の炎症性の皮膚病の場合の炎症を起こした皮膚の手入れおよびケアのため、物理的、化学的および生物学的影響、特にUVおよびIR放射および変性物質に対するヒトの皮膚細胞の保護および安定化のため、皮膚のミクロフローラ(microflora)の保護のため、天然の皮膚バリアの安定化のため、およびフリーラジカルスカベンジャー(scavenger)および/または酸化防止剤としての、化粧品製剤を産生するための請求項14記載の方法。
- アトピー性皮膚炎、乾癬および他の炎症性の皮膚病並びに湿疹の手入れ、ケア、予防または治療のための医薬品および/または薬剤を産生するための請求項14記載の方法。
- 前記オスモライトがエクトインまたはヒドロキシエクトインであることを特徴とする請求項14から16いずれか1項記載の方法。
- 前記製剤が、溶液、懸濁液、エマルジョン、ペースト、軟膏、ゲル、クリーム、ローション、パウダー、石鹸、界面活性剤含有洗浄剤、オイル、リップスティック、マスカラ、アイライナー、アイシャドウ、口紅、粉末、エマルジョンおよびワックス化粧品、日焼け止め剤、日焼け前および後の処理剤、ヘアートニック、絆創膏、包帯またはスプレーの形態で供給されることを特徴とする請求項14から17いずれか1項記載の化粧品製剤。
- 前記製剤がさらに、少なくとも1つのUVフィルター、酵素、ビタミン、ビタミン誘導体および/またはタンパク質を含有することを特徴とする請求項18記載の方法。
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DE102004016045 | 2004-03-30 | ||
DE102004049062A DE102004049062A1 (de) | 2004-03-30 | 2004-10-08 | Topische Zubereitung zur Anwendung auf der Haut enthaltend natürliches Öl der Nachtkerze (Oenothera biennis) (=Oleum Oenothera) und Osmolyte aus extremophilen Mikroorganismen |
PCT/EP2005/003342 WO2005094771A1 (de) | 2004-03-30 | 2005-03-30 | Topische zubereitung zur anwendung auf der haut enthaltend natürliches öl der nachtkerze (oenothera biennis) (=oleum oenotherae) und osmolyte aus extremophilen mikroorganismen |
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US (1) | US20080014153A1 (ja) |
EP (1) | EP1732651A1 (ja) |
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JP2013515778A (ja) * | 2009-12-30 | 2013-05-09 | ザ プロクター アンド ギャンブル カンパニー | ω−6脂肪酸を含むローション組成物を含む拭き取り用物品 |
JP2016528164A (ja) * | 2013-04-10 | 2016-09-15 | ユーエックスエヌ シーオー.,エルティーディー. | ゴールドビーズを含有した石鹸組成物または化粧品組成物、およびこれを用いた石鹸の製造方法または化粧品の製造方法 |
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US9089568B2 (en) * | 2005-03-12 | 2015-07-28 | Bitop Ag | Method of using compatible solutes containing ectoine and/or hydroxyectoine |
DE102006056766A1 (de) * | 2006-12-01 | 2008-06-05 | Bitop Ag | Verwendung von kompatiblen Soluten |
DE102007013857A1 (de) * | 2007-03-20 | 2008-09-25 | Maria Clementine Martin Klosterfrau Vertriebsgesellschaft Mbh | Neue Zusammensetzungen, insbesondere für die topische Behandlung von Hauterkrankungen |
FR2916977A1 (fr) * | 2007-06-06 | 2008-12-12 | Engelhard Lyon Sa | STIMULATION DE LA SYNTHESE DES RECPTEURS MCR1, MCR2 ET µ OPIOIDE. |
DE102007040615A1 (de) * | 2007-08-27 | 2009-03-05 | Bitop Ag | Osmolyte zur Behandlung von allergisch oder viral bedingten Atemwegserkrankungen |
DE102007052380A1 (de) † | 2007-10-31 | 2009-05-07 | Bitop Ag | Osmolythaltige Zubereitungen zur Anwendung bei trockenen Schleimhäuten |
DE102008039231A1 (de) * | 2008-08-22 | 2010-02-25 | Bitop Ag | Verwendung von Glucosylglycerol |
EP2184052B1 (en) * | 2008-11-11 | 2017-09-20 | Kao Germany GmbH | Composition for hair |
KR101275351B1 (ko) * | 2010-06-29 | 2013-06-17 | (주)아모레퍼시픽 | 노화방지용 화장료 조성물 |
WO2012075093A2 (en) * | 2010-12-01 | 2012-06-07 | Nostrum Laboratories, Inc. | Topical formulations for administration of omega-3 fatty acids |
CN102274229A (zh) * | 2011-09-01 | 2011-12-14 | 朱道辰 | 一种治疗皮炎的外用药物及其制法 |
US11576853B2 (en) | 2015-04-29 | 2023-02-14 | CSI: Create.Solve. Innovate. LLC | Antioxidant compositions and methods of protecting skin, hair and nails against high energy blue-violet light |
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JP2016528164A (ja) * | 2013-04-10 | 2016-09-15 | ユーエックスエヌ シーオー.,エルティーディー. | ゴールドビーズを含有した石鹸組成物または化粧品組成物、およびこれを用いた石鹸の製造方法または化粧品の製造方法 |
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WO2005094771A1 (de) | 2005-10-13 |
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EP1732651A1 (de) | 2006-12-20 |
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