JP2007526094A5 - - Google Patents
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- Publication number
- JP2007526094A5 JP2007526094A5 JP2007502011A JP2007502011A JP2007526094A5 JP 2007526094 A5 JP2007526094 A5 JP 2007526094A5 JP 2007502011 A JP2007502011 A JP 2007502011A JP 2007502011 A JP2007502011 A JP 2007502011A JP 2007526094 A5 JP2007526094 A5 JP 2007526094A5
- Authority
- JP
- Japan
- Prior art keywords
- gum
- ions
- polymer
- polysaccharide
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000463 material Substances 0.000 claims 11
- 150000004676 glycans Chemical class 0.000 claims 7
- 229920001282 polysaccharide Polymers 0.000 claims 7
- 239000005017 polysaccharide Substances 0.000 claims 7
- -1 borate ester Chemical class 0.000 claims 5
- 150000003839 salts Chemical class 0.000 claims 5
- 229920006318 anionic polymer Polymers 0.000 claims 4
- 238000004519 manufacturing process Methods 0.000 claims 4
- 229910052751 metal Inorganic materials 0.000 claims 4
- 239000002184 metal Substances 0.000 claims 4
- 229920000642 polymer Polymers 0.000 claims 4
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims 3
- 230000000903 blocking effect Effects 0.000 claims 3
- 239000001768 carboxy methyl cellulose Substances 0.000 claims 3
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims 3
- 125000002057 carboxymethyl group Chemical group [H]OC(=O)C([H])([H])[*] 0.000 claims 3
- 239000008112 carboxymethyl-cellulose Substances 0.000 claims 3
- 239000012530 fluid Substances 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- 239000002861 polymer material Substances 0.000 claims 3
- 239000000243 solution Substances 0.000 claims 3
- 239000000126 substance Substances 0.000 claims 3
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 claims 2
- GJCOSYZMQJWQCA-UHFFFAOYSA-N 9H-xanthene Chemical compound C1=CC=C2CC3=CC=CC=C3OC2=C1 GJCOSYZMQJWQCA-UHFFFAOYSA-N 0.000 claims 2
- 244000215068 Acacia senegal Species 0.000 claims 2
- 229920002148 Gellan gum Polymers 0.000 claims 2
- 229920000084 Gum arabic Polymers 0.000 claims 2
- 229920000569 Gum karaya Polymers 0.000 claims 2
- 235000010451 Plantago psyllium Nutrition 0.000 claims 2
- 244000090599 Plantago psyllium Species 0.000 claims 2
- 241001494501 Prosopis <angiosperm> Species 0.000 claims 2
- 235000001560 Prosopis chilensis Nutrition 0.000 claims 2
- 235000014460 Prosopis juliflora var juliflora Nutrition 0.000 claims 2
- 241000083513 Punctum Species 0.000 claims 2
- 241000934878 Sterculia Species 0.000 claims 2
- 229920002310 Welan gum Polymers 0.000 claims 2
- 235000010489 acacia gum Nutrition 0.000 claims 2
- 239000000205 acacia gum Substances 0.000 claims 2
- 229940072056 alginate Drugs 0.000 claims 2
- 235000010443 alginic acid Nutrition 0.000 claims 2
- 229920000615 alginic acid Polymers 0.000 claims 2
- 239000003242 anti bacterial agent Substances 0.000 claims 2
- 230000002421 anti-septic effect Effects 0.000 claims 2
- 235000010418 carrageenan Nutrition 0.000 claims 2
- 239000000679 carrageenan Substances 0.000 claims 2
- 229920001525 carrageenan Polymers 0.000 claims 2
- 229940113118 carrageenan Drugs 0.000 claims 2
- 150000001768 cations Chemical class 0.000 claims 2
- 239000000017 hydrogel Substances 0.000 claims 2
- 150000002500 ions Chemical class 0.000 claims 2
- 235000010494 karaya gum Nutrition 0.000 claims 2
- 239000000231 karaya gum Substances 0.000 claims 2
- 229940039371 karaya gum Drugs 0.000 claims 2
- 239000001814 pectin Substances 0.000 claims 2
- 235000010987 pectin Nutrition 0.000 claims 2
- 229920001277 pectin Polymers 0.000 claims 2
- 239000002504 physiological saline solution Substances 0.000 claims 2
- 229910052709 silver Inorganic materials 0.000 claims 2
- 239000004332 silver Substances 0.000 claims 2
- 229910001428 transition metal ion Inorganic materials 0.000 claims 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 2
- 229920001285 xanthan gum Polymers 0.000 claims 2
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 claims 2
- DJHGAFSJWGLOIV-UHFFFAOYSA-K Arsenate3- Chemical compound [O-][As]([O-])([O-])=O DJHGAFSJWGLOIV-UHFFFAOYSA-K 0.000 claims 1
- BTBUEUYNUDRHOZ-UHFFFAOYSA-N Borate Chemical compound [O-]B([O-])[O-] BTBUEUYNUDRHOZ-UHFFFAOYSA-N 0.000 claims 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims 1
- 229920001661 Chitosan Polymers 0.000 claims 1
- 229920002785 Croscarmellose sodium Polymers 0.000 claims 1
- JPVYNHNXODAKFH-UHFFFAOYSA-N Cu2+ Chemical compound [Cu+2] JPVYNHNXODAKFH-UHFFFAOYSA-N 0.000 claims 1
- 229920002558 Curdlan Polymers 0.000 claims 1
- 239000001879 Curdlan Substances 0.000 claims 1
- 244000303965 Cyamopsis psoralioides Species 0.000 claims 1
- 229920002907 Guar gum Polymers 0.000 claims 1
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 claims 1
- BPQQTUXANYXVAA-UHFFFAOYSA-N Orthosilicate Chemical compound [O-][Si]([O-])([O-])[O-] BPQQTUXANYXVAA-UHFFFAOYSA-N 0.000 claims 1
- 229910019142 PO4 Inorganic materials 0.000 claims 1
- 229920002125 Sokalan® Polymers 0.000 claims 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 claims 1
- UCKMPCXJQFINFW-UHFFFAOYSA-N Sulphide Chemical compound [S-2] UCKMPCXJQFINFW-UHFFFAOYSA-N 0.000 claims 1
- VJHCJDRQFCCTHL-UHFFFAOYSA-N acetic acid 2,3,4,5,6-pentahydroxyhexanal Chemical compound CC(O)=O.OCC(O)C(O)C(O)C(O)C=O VJHCJDRQFCCTHL-UHFFFAOYSA-N 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 229940000489 arsenate Drugs 0.000 claims 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 claims 1
- 239000013060 biological fluid Substances 0.000 claims 1
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 claims 1
- 239000004327 boric acid Substances 0.000 claims 1
- 229940105329 carboxymethylcellulose Drugs 0.000 claims 1
- 238000006243 chemical reaction Methods 0.000 claims 1
- 239000007795 chemical reaction product Substances 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- ZCDOYSPFYFSLEW-UHFFFAOYSA-N chromate(2-) Chemical compound [O-][Cr]([O-])(=O)=O ZCDOYSPFYFSLEW-UHFFFAOYSA-N 0.000 claims 1
- 239000002131 composite material Substances 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 229910001431 copper ion Inorganic materials 0.000 claims 1
- 229960005168 croscarmellose Drugs 0.000 claims 1
- 239000001767 crosslinked sodium carboxy methyl cellulose Substances 0.000 claims 1
- 235000019316 curdlan Nutrition 0.000 claims 1
- 229940078035 curdlan Drugs 0.000 claims 1
- 238000007598 dipping method Methods 0.000 claims 1
- 238000004090 dissolution Methods 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000000665 guar gum Substances 0.000 claims 1
- 235000010417 guar gum Nutrition 0.000 claims 1
- 229960002154 guar gum Drugs 0.000 claims 1
- 150000004820 halides Chemical class 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical compound [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 claims 1
- 239000001863 hydroxypropyl cellulose Substances 0.000 claims 1
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 claims 1
- 239000000819 hypertonic solution Substances 0.000 claims 1
- 229940021223 hypertonic solution Drugs 0.000 claims 1
- 229910052500 inorganic mineral Inorganic materials 0.000 claims 1
- XEEYBQQBJWHFJM-UHFFFAOYSA-N iron Substances [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims 1
- 229910052742 iron Inorganic materials 0.000 claims 1
- 239000004973 liquid crystal related substance Substances 0.000 claims 1
- 239000011707 mineral Substances 0.000 claims 1
- MEFBJEMVZONFCJ-UHFFFAOYSA-N molybdate Chemical compound [O-][Mo]([O-])(=O)=O MEFBJEMVZONFCJ-UHFFFAOYSA-N 0.000 claims 1
- 150000007524 organic acids Chemical class 0.000 claims 1
- 239000003960 organic solvent Substances 0.000 claims 1
- 230000003204 osmotic effect Effects 0.000 claims 1
- 239000007800 oxidant agent Substances 0.000 claims 1
- 238000010525 oxidative degradation reaction Methods 0.000 claims 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims 1
- 239000010452 phosphate Substances 0.000 claims 1
- 230000004962 physiological condition Effects 0.000 claims 1
- 239000000047 product Substances 0.000 claims 1
- GGCZERPQGJTIQP-UHFFFAOYSA-N sodium;9,10-dioxoanthracene-2-sulfonic acid Chemical compound [Na+].C1=CC=C2C(=O)C3=CC(S(=O)(=O)O)=CC=C3C(=O)C2=C1 GGCZERPQGJTIQP-UHFFFAOYSA-N 0.000 claims 1
- 239000007921 spray Substances 0.000 claims 1
- 229940124597 therapeutic agent Drugs 0.000 claims 1
- PBYZMCDFOULPGH-UHFFFAOYSA-N tungstate Chemical compound [O-][W]([O-])(=O)=O PBYZMCDFOULPGH-UHFFFAOYSA-N 0.000 claims 1
- LSGOVYNHVSXFFJ-UHFFFAOYSA-N vanadate(3-) Chemical compound [O-][V]([O-])([O-])=O LSGOVYNHVSXFFJ-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US55013204P | 2004-03-04 | 2004-03-04 | |
| US55736804P | 2004-03-29 | 2004-03-29 | |
| US56485804P | 2004-04-23 | 2004-04-23 | |
| US63756904P | 2004-12-20 | 2004-12-20 | |
| US11/071,866 US20050220882A1 (en) | 2004-03-04 | 2005-03-03 | Materials for medical implants and occlusive devices |
| PCT/US2005/007095 WO2005086694A2 (en) | 2004-03-04 | 2005-03-04 | Occlusive biomedical devices, punctum plugs, and methods of use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007526094A JP2007526094A (ja) | 2007-09-13 |
| JP2007526094A5 true JP2007526094A5 (https=) | 2009-04-16 |
Family
ID=34976091
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007502011A Pending JP2007526094A (ja) | 2004-03-04 | 2005-03-04 | 生物医学的閉塞デバイス、涙点プラグ、及びそれらの使用方法 |
| JP2007502012A Pending JP2007526095A (ja) | 2004-03-04 | 2005-03-04 | 医療インプラント、及び閉塞性デバイスの材料 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007502012A Pending JP2007526095A (ja) | 2004-03-04 | 2005-03-04 | 医療インプラント、及び閉塞性デバイスの材料 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20050220882A1 (https=) |
| EP (1) | EP1744765A2 (https=) |
| JP (2) | JP2007526094A (https=) |
| AU (1) | AU2005220764A1 (https=) |
| CA (1) | CA2560176A1 (https=) |
| WO (2) | WO2005086697A2 (https=) |
Families Citing this family (86)
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- 2005-03-04 JP JP2007502011A patent/JP2007526094A/ja active Pending
- 2005-03-04 WO PCT/US2005/007099 patent/WO2005086697A2/en not_active Ceased
- 2005-03-04 EP EP05730783A patent/EP1744765A2/en not_active Withdrawn
- 2005-03-04 AU AU2005220764A patent/AU2005220764A1/en not_active Abandoned
- 2005-03-04 CA CA002560176A patent/CA2560176A1/en not_active Abandoned
- 2005-03-04 JP JP2007502012A patent/JP2007526095A/ja active Pending
- 2005-03-04 WO PCT/US2005/007095 patent/WO2005086694A2/en not_active Ceased
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2007
- 2007-03-16 US US11/724,923 patent/US20070160647A1/en not_active Abandoned
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