JP2007520494A5 - - Google Patents
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- JP2007520494A5 JP2007520494A5 JP2006551599A JP2006551599A JP2007520494A5 JP 2007520494 A5 JP2007520494 A5 JP 2007520494A5 JP 2006551599 A JP2006551599 A JP 2006551599A JP 2006551599 A JP2006551599 A JP 2006551599A JP 2007520494 A5 JP2007520494 A5 JP 2007520494A5
- Authority
- JP
- Japan
- Prior art keywords
- subject
- composition
- molecule
- red blood
- type iii
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/771,552 US20050169921A1 (en) | 2004-02-03 | 2004-02-03 | Method of treating hemolytic disease |
| PCT/US2005/003225 WO2005074607A2 (en) | 2004-02-03 | 2005-02-03 | Method of treating hemolytic disease |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011065075A Division JP2011126917A (ja) | 2004-02-03 | 2011-03-23 | 溶血性疾患の処置方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007520494A JP2007520494A (ja) | 2007-07-26 |
| JP2007520494A5 true JP2007520494A5 (enExample) | 2008-03-27 |
Family
ID=34808492
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006551599A Withdrawn JP2007520494A (ja) | 2004-02-03 | 2005-02-03 | 溶血性疾患の処置方法 |
| JP2011065075A Withdrawn JP2011126917A (ja) | 2004-02-03 | 2011-03-23 | 溶血性疾患の処置方法 |
| JP2013145341A Expired - Lifetime JP5873047B2 (ja) | 2004-02-03 | 2013-07-11 | 溶血性疾患の処置方法 |
| JP2015015028A Withdrawn JP2015083611A (ja) | 2004-02-03 | 2015-01-29 | 溶血性疾患の処置方法 |
| JP2017000897A Pending JP2017057234A (ja) | 2004-02-03 | 2017-01-06 | 溶血性疾患の処置方法 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011065075A Withdrawn JP2011126917A (ja) | 2004-02-03 | 2011-03-23 | 溶血性疾患の処置方法 |
| JP2013145341A Expired - Lifetime JP5873047B2 (ja) | 2004-02-03 | 2013-07-11 | 溶血性疾患の処置方法 |
| JP2015015028A Withdrawn JP2015083611A (ja) | 2004-02-03 | 2015-01-29 | 溶血性疾患の処置方法 |
| JP2017000897A Pending JP2017057234A (ja) | 2004-02-03 | 2017-01-06 | 溶血性疾患の処置方法 |
Country Status (16)
| Country | Link |
|---|---|
| US (5) | US20050169921A1 (enExample) |
| EP (7) | EP2910253A1 (enExample) |
| JP (5) | JP2007520494A (enExample) |
| KR (1) | KR101197799B1 (enExample) |
| CN (4) | CN103977403A (enExample) |
| AU (1) | AU2005209854B2 (enExample) |
| CA (1) | CA2554632A1 (enExample) |
| CY (1) | CY1113190T1 (enExample) |
| DK (1) | DK1720571T3 (enExample) |
| ES (1) | ES2389093T3 (enExample) |
| IL (2) | IL177003A0 (enExample) |
| NZ (1) | NZ549328A (enExample) |
| PL (1) | PL1720571T3 (enExample) |
| PT (1) | PT1720571E (enExample) |
| SI (1) | SI1720571T1 (enExample) |
| WO (1) | WO2005074607A2 (enExample) |
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6969601B2 (en) | 1997-04-03 | 2005-11-29 | Jensenius Jens Chr | MASP-2, a complement-fixing enzyme, and uses for it |
| AU2003270330B2 (en) * | 2002-09-06 | 2009-07-30 | Alexion Pharmaceuticals, Inc. | Method of treatment of asthma using antibodies to complement component C5 |
| US9415102B2 (en) | 2002-09-06 | 2016-08-16 | Alexion Pharmaceuticals, Inc. | High concentration formulations of anti-C5 antibodies |
| US20050271660A1 (en) | 2002-09-06 | 2005-12-08 | Alexion Pharmaceuticals, Inc. | Nebulization of monoclonal antibodies for treating pulmonary diseases |
| US20070116710A1 (en) * | 2004-02-03 | 2007-05-24 | Leonard Bell | Methods of treating hemolytic anemia |
| US20050169921A1 (en) * | 2004-02-03 | 2005-08-04 | Leonard Bell | Method of treating hemolytic disease |
| DK1755674T3 (en) * | 2004-05-14 | 2015-02-09 | Alexion Pharma Inc | PROLONGED SURVIVAL OF A allograft by inhibiting complement activity |
| US8951522B2 (en) * | 2011-04-08 | 2015-02-10 | University Of Leicester | Methods for treating conditions associated with MASP-2 dependent complement activation |
| US8840893B2 (en) | 2004-06-10 | 2014-09-23 | Omeros Corporation | Methods for treating conditions associated with MASP-2 dependent complement activation |
| US7919094B2 (en) * | 2004-06-10 | 2011-04-05 | Omeros Corporation | Methods for treating conditions associated with MASP-2 dependent complement activation |
| WO2006107708A1 (en) * | 2005-04-04 | 2006-10-12 | Alexion Pharmaceuticals, Inc. | Treatment of disease caused by excess free hemoglobin |
| HUE026423T2 (en) * | 2005-11-04 | 2016-05-30 | Genentech Inc | Use of complement biosynthetic pathway inhibitors for treating eye diseases |
| CA2644020C (en) * | 2006-03-02 | 2016-05-10 | Alexion Pharmaceuticals, Inc. | Prolongation of survival of an allograft by inhibiting complement activity |
| SI2359834T1 (sl) * | 2006-03-15 | 2017-02-28 | Alexion Pharmaceuticals, Inc. | Zdravljenje pacientov,ki imajo paroksizmalno nočno hemoglobinurijo, z zaviralcem komplementa |
| IN2014DN10515A (enExample) | 2006-03-31 | 2015-08-21 | Chugai Pharmaceutical Co Ltd | |
| NZ576195A (en) | 2006-10-10 | 2012-04-27 | Az Univ Amsterdam | Complement inhibition for improved nerve regeneration |
| SI2097455T1 (sl) * | 2006-11-02 | 2015-03-31 | Genentech, Inc. | Humanizirana protitelesa proti faktorju tipa d |
| MX336725B (es) | 2007-09-26 | 2016-01-28 | Chugai Pharmaceutical Co Ltd | Metodo de modificacion del punto isoelectrico de anticuerpos medinate la sustitucion de aminoacidos en region de determinacion de complementariedad (cdr). |
| TWI700293B (zh) | 2008-04-11 | 2020-08-01 | 日商中外製藥股份有限公司 | 重複結合複數個抗原的抗體 |
| CR20170001A (es) | 2008-04-28 | 2017-08-10 | Genentech Inc | Anticuerpos anti factor d humanizados |
| PY09026846A (es) * | 2008-08-05 | 2015-09-01 | Novartis Ag | Composiciones y métodos para anticuerpos que se dirigen a la proteína de complemento c5 |
| HUE061548T2 (hu) * | 2008-11-10 | 2023-07-28 | Alexion Pharma Inc | Komplementtel összefüggõ rendellenességek kezelésére szolgáló eljárások és készítmények |
| AU2010306581B2 (en) * | 2009-10-16 | 2015-03-19 | Omeros Corporation | Methods for treating disseminated intravascular coagulation by inhibiting MASP-2 dependent complement activation |
| US20110124019A1 (en) * | 2009-11-25 | 2011-05-26 | The Charlotte-Mecklenburg Hospital Authority | Method of using carbonic anhydrase to detect hemolysis |
| US9420770B2 (en) | 2009-12-01 | 2016-08-23 | Indiana University Research & Technology Corporation | Methods of modulating thrombocytopenia and modified transgenic pigs |
| EP2545079A2 (en) * | 2010-03-11 | 2013-01-16 | Rinat Neuroscience Corporation | ANTIBODIES WITH pH DEPENDENT ANTIGEN BINDING |
| KR102568454B1 (ko) | 2010-11-30 | 2023-08-18 | 추가이 세이야쿠 가부시키가이샤 | 복수 분자의 항원에 반복해서 결합하는 항원 결합 분자 |
| AU2015230852B2 (en) * | 2011-03-08 | 2017-09-14 | Alexion Pharmaceuticals, Inc. | High concentration antibody formulations |
| US9644035B2 (en) | 2011-04-08 | 2017-05-09 | Omeros Corporation | Methods for treating conditions associated with MASP-2 dependent complement activation |
| PE20150159A1 (es) | 2011-12-21 | 2015-02-08 | Novartis Ag | Composiciones y metodos para anticuerpos que actuan sobre el factor p |
| HK1204693A1 (en) * | 2012-03-16 | 2015-11-27 | Alexion Pharmaceuticals, Inc. | Methods of distributing complement-inhibiting drugs to patients receiving a complement inhibitor |
| EP2833907B1 (en) * | 2012-04-06 | 2018-02-28 | Omeros Corporation | Compositions and methods of inhibting masp-1 and/or masp-3 for the treatment of paroxysmal nocturnal hemoglobinuria |
| US9579360B2 (en) * | 2012-06-20 | 2017-02-28 | The Trustees Of The University Of Pennsylvania | Methods of treating or preventing periodontitis and diseases associated with periodontitis |
| US20160051673A1 (en) * | 2013-03-29 | 2016-02-25 | Alexion Pharmaceuticals, Inc. | Compositions and methods for increasing the serum half-life of a therapeutic agent targeting complement c5 |
| KR101834469B1 (ko) | 2013-08-07 | 2018-03-06 | 알렉시온 파마슈티칼스, 인코포레이티드 | 비정형적 용혈성 요독증후군 (ahus) 바이오마커 단백질 |
| CA2920666A1 (en) | 2013-08-12 | 2015-02-19 | Genentech, Inc. | Compositions and method for treating complement-associated conditions |
| LT3057993T (lt) | 2013-10-17 | 2020-11-25 | Omeros Corporation | Gydymo būdai būklių, susijusių su nuo masp-2 priklausomu komplemento aktyvinimu |
| CR20160561A (es) | 2014-05-01 | 2017-05-03 | Genentech Inc | Variantes del anticuerpo anti-factor d y sus usos |
| TWI656133B (zh) | 2014-12-19 | 2019-04-11 | 日商中外製藥股份有限公司 | 抗肌抑素之抗體、含變異Fc區域之多胜肽及使用方法 |
| KR101838645B1 (ko) | 2014-12-19 | 2018-03-14 | 추가이 세이야쿠 가부시키가이샤 | 항-c5 항체 및 그의 사용 방법 |
| JP2018511557A (ja) | 2015-01-22 | 2018-04-26 | 中外製薬株式会社 | 2種以上の抗c5抗体の組み合わせおよび使用方法 |
| JP6944375B2 (ja) * | 2015-03-31 | 2021-10-06 | アレクシオン ファーマシューティカルズ, インコーポレイテッド | 発作性夜間血色素尿症(pnh)患者の亜集団の同定および処置 |
| US10654932B2 (en) | 2015-10-30 | 2020-05-19 | Genentech, Inc. | Anti-factor D antibody variant conjugates and uses thereof |
| US10407510B2 (en) | 2015-10-30 | 2019-09-10 | Genentech, Inc. | Anti-factor D antibodies and conjugates |
| KR102667023B1 (ko) | 2016-06-14 | 2024-05-21 | 리제너론 파아마슈티컬스, 인크. | 항-c5 항체 및 이의 용도 |
| CN109689099B (zh) | 2016-08-05 | 2023-02-28 | 中外制药株式会社 | 用于预防或治疗il-8相关疾病的组合物 |
| IT201600121482A1 (it) * | 2016-11-30 | 2018-05-30 | Univ Degli Studi Di Verona | Fattore H per l’uso nel trattamento e/o prevenzione della formazione di eterotrombi in pazienti affetti da anemia falciforme |
| PL3577135T3 (pl) | 2017-01-31 | 2023-12-04 | Chugai Seiyaku Kabushiki Kaisha | Kompozycja farmaceutyczna do stosowania do leczenia lub zapobiegania chorobom związanym z c5 |
| CN120571008A (zh) | 2017-12-13 | 2025-09-02 | 瑞泽恩制药公司 | 抗c5抗体组合及其用途 |
| GB201800620D0 (en) | 2018-01-15 | 2018-02-28 | Univ Manchester | C3b Binding Polypeptide |
| US20190247560A1 (en) | 2018-02-13 | 2019-08-15 | Gambro Lundia Ab | Extracorporeal devices and methods of treating complement factor related diseases |
| CR20210103A (es) | 2018-08-01 | 2021-03-22 | Chugai Pharmaceutical Co Ltd | Composición farmacéutica para usarse en el tratamiento o prevención de una enfermedad relacionada con c5 y método para tratar o prevenir una enfermedad relacionada con c5 |
| EP4003408A1 (en) | 2019-07-31 | 2022-06-01 | F. Hoffmann-La Roche AG | Dosage and administration regimen for the treatment or prevention of c5-related diseases by the use of the anti-c5 antibody crovalimab |
| WO2021019036A1 (en) | 2019-07-31 | 2021-02-04 | F. Hoffmann-La Roche Ag | Dosage and administration regimen for the treatment or prevention of c5-related diseases by the use of the anti-c5 antibody crovalimab |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4686100A (en) * | 1985-04-02 | 1987-08-11 | The Board Of Trustees Of The Leland Stanford Junior University | Method for the treatment of adult respiratory distress syndrome |
| US5135916A (en) * | 1989-06-12 | 1992-08-04 | Oklahoma Medical Research Foundation | Inhibition of complement mediated inflammatory response |
| DE3924924A1 (de) | 1989-07-27 | 1991-02-07 | Goetze Otto | Verfahren zum nachweis und/oder der quantitativen bestimmung von komplementpeptid c5a und/oder c5adesarg |
| US6074642A (en) * | 1994-05-02 | 2000-06-13 | Alexion Pharmaceuticals, Inc. | Use of antibodies specific to human complement component C5 for the treatment of glomerulonephritis |
| US5650825A (en) * | 1995-03-31 | 1997-07-22 | Matsushita Electric Corporation Of America | Method and apparatus for sending private data instead of stuffing bits in an MPEG bit stream |
| DE19826743A1 (de) * | 1998-06-16 | 1999-12-23 | Bayer Ag | Verfahren zur Herstellung von geträgerten Polymerisationskatalysatorsystemen und Verwendung dieser zur Homo- und Copolymerisation ungesättigter Monomere |
| CA2436671C (en) * | 2000-12-05 | 2015-02-03 | Alexion Pharmaceuticals, Inc. | Rationally designed antibodies |
| WO2003081206A2 (en) * | 2002-03-18 | 2003-10-02 | Alexion Pharmaceuticals, Inc. | Stratification of patient populations having or suspected of having rheumatoid arthritis |
| US7361339B2 (en) * | 2003-01-09 | 2008-04-22 | Alexion Pharmaceuticals, Inc. | Methods for reducing morality associated with acute myocardial infarction |
| US20050169921A1 (en) * | 2004-02-03 | 2005-08-04 | Leonard Bell | Method of treating hemolytic disease |
-
2004
- 2004-02-03 US US10/771,552 patent/US20050169921A1/en not_active Abandoned
-
2005
- 2005-02-03 CN CN201410147935.2A patent/CN103977403A/zh active Pending
- 2005-02-03 DK DK05712607.0T patent/DK1720571T3/da active
- 2005-02-03 KR KR1020067017880A patent/KR101197799B1/ko not_active Ceased
- 2005-02-03 US US11/050,543 patent/US20050191298A1/en not_active Abandoned
- 2005-02-03 ES ES05712607T patent/ES2389093T3/es not_active Expired - Lifetime
- 2005-02-03 EP EP15150658.1A patent/EP2910253A1/en not_active Withdrawn
- 2005-02-03 WO PCT/US2005/003225 patent/WO2005074607A2/en not_active Ceased
- 2005-02-03 PL PL05712607T patent/PL1720571T3/pl unknown
- 2005-02-03 SI SI200531579T patent/SI1720571T1/sl unknown
- 2005-02-03 AU AU2005209854A patent/AU2005209854B2/en not_active Expired
- 2005-02-03 PT PT05712607T patent/PT1720571E/pt unknown
- 2005-02-03 EP EP05712607A patent/EP1720571B9/en not_active Revoked
- 2005-02-03 EP EP12169513A patent/EP2522362A1/en not_active Withdrawn
- 2005-02-03 NZ NZ549328A patent/NZ549328A/en not_active IP Right Cessation
- 2005-02-03 JP JP2006551599A patent/JP2007520494A/ja not_active Withdrawn
- 2005-02-03 CA CA002554632A patent/CA2554632A1/en not_active Abandoned
- 2005-02-03 EP EP12169508A patent/EP2520311A3/en not_active Withdrawn
- 2005-02-03 EP EP12169343A patent/EP2522361A1/en not_active Withdrawn
- 2005-02-03 EP EP12169526A patent/EP2522364A1/en not_active Withdrawn
- 2005-02-03 CN CNA2005800106310A patent/CN1938047A/zh active Pending
- 2005-02-03 CN CN2013103817575A patent/CN103446584A/zh active Pending
- 2005-02-03 EP EP12169519A patent/EP2522363A1/en not_active Withdrawn
- 2005-02-03 CN CN201410147793.XA patent/CN103977402A/zh active Pending
-
2006
- 2006-07-20 IL IL177003A patent/IL177003A0/en unknown
-
2009
- 2009-11-19 US US12/621,792 patent/US20100068202A1/en not_active Abandoned
-
2010
- 2010-10-12 US US12/902,617 patent/US20110086040A1/en not_active Abandoned
-
2011
- 2011-03-23 JP JP2011065075A patent/JP2011126917A/ja not_active Withdrawn
- 2011-12-22 US US13/335,518 patent/US20120308559A1/en not_active Abandoned
-
2012
- 2012-08-30 CY CY20121100783T patent/CY1113190T1/el unknown
-
2013
- 2013-07-11 JP JP2013145341A patent/JP5873047B2/ja not_active Expired - Lifetime
-
2015
- 2015-01-29 JP JP2015015028A patent/JP2015083611A/ja not_active Withdrawn
- 2015-08-06 IL IL240410A patent/IL240410A0/en unknown
-
2017
- 2017-01-06 JP JP2017000897A patent/JP2017057234A/ja active Pending
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